Inhibition of glutathione S-Transferase M1 by new gabosine analogues is essential for overcoming cisplatin resistance in lung cancer cells

Journal of Medicinal Chemistry

Volumn 54, Issue 24, 2011, Pages 8574-8581

  Wang, Chie Hong ^a   Wu, Ho T ^b   Cheng, Hau M ^b   Yen, Tien Jui ^a   Lu, I Hsuan ^a   Chang, Hui Chuan ^a   Jao, Shu Chuan ^c   Shing, Tony K M ^a,b   Li, Wen Shan ^a,d  

^a INSTITUTE OF CHEMISTRY   (Taiwan)

^b CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^c INSTITUTE OF BIOLOGICAL CHEMISTRY   (Taiwan)

^d NATIONAL SUN YAT SEN UNIVERSITY   (Taiwan)

Author keywords

[No Author keywords available]

Indexed keywords

4 EPI GABOSINE; 4 O DECYL GABOSINE D; ANTINEOPLASTIC AGENT; CISPLATIN; DOXORUBICIN; GABOSINE D; GABOSINE DERIVATIVE; GABOSINE G; GLUTATHIONE TRANSFERASE M1; OXALIPLATIN; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER RESISTANCE; CELL LINE; DRUG POTENTIATION; DRUG SYNTHESIS; ENZYME INHIBITION; EPITHELIUM CELL; GENE SILENCING; HUMAN; HUMAN CELL; LUNG ADENOCARCINOMA; LUNG ALVEOLUS EPITHELIUM;

ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL SURVIVAL; CISPLATIN; CYCLOHEXANONES; DRUG RESISTANCE, NEOPLASM; DRUG SCREENING ASSAYS, ANTITUMOR; DRUG SYNERGISM; GLUTATHIONE TRANSFERASE; HUMANS; ISOENZYMES; LUNG NEOPLASMS; RNA, SMALL INTERFERING; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84055221800     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/jm201131n     Document Type: Article

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