Exploiting the acylating nature of the imide-ugi intermediate: A straightforward synthesis of tetrahydro-1,4-benzodiazepin-2-ones

Journal of Organic Chemistry

Volumn 76, Issue 24, 2011, Pages 10258-10262

  Mossetti, Riccardo ^a   Saggiorato, Dèsirèe ^a   Tron, Gian Cesare ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

MULTI-COMPONENT REACTIONS; STAUDINGER REDUCTION;

CHEMISTRY; ORGANIC COMPOUNDS;

SYNTHESIS (CHEMICAL);

3,4 DIBENZYL 7 BROMO 4,5 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 2 (3H) 1; 4 (4 CHLOROBENZYL) 3 ISOPROPYL 4,5 DIHYDRO 1H NAPHTHO[2,3 E][1,4]DIAZEPIN 2 (3H) 1; 4 BENZYL 3 (4 CHLOROPHENYL) 4,5 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 2 (3H) 1; 4 BENZYL 3 (4 FLUOROPHENYL) 4,5 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 2 (3H) 1; 4 BENZYL 3 (4 METHOXYPHENYL) 4,5 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 2 (3H) 1; 4 BENZYL 3 CYCLOHEXYL 4,5 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 2 (3H) 1; 4 BENZYL 3 HEXYL 4,5 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 2 (3H) 1; 4 BENZYL 3 ISOPROPYL 4,5 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 2 (3H) 1; 4 BENZYL 3 PHENYL 4,5 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 2 (3H) 1; 4 BENZYL 7 BROMO 3 HEXYL 4,5 DIHYDRO 1H BENZO[E][1,4] DIAZEPIN 2 (3H) 1; 4 BUTYL 7,8 DIMETHOXY 3 (THIOPHEN 2 YL) 4,5 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 2 (3H) 1; 4 CYCLOPROPYL 3 HEXYL 4,5 DIHYDRO 1H BENZO[E][1,4]DIAZEPIN 2(3H) 1; BENZODIAZEPIN 2 ONE DERIVATIVE; IMIDE; UNCLASSIFIED DRUG;

ACYLATION; ARTICLE; DRUG SYNTHESIS; REDUCTION; STAUDINGER REACTION;

ACYLATION; ANTI-HIV AGENTS; ANTINEOPLASTIC AGENTS; BENZODIAZEPINONES; CHEMISTRY TECHNIQUES, SYNTHETIC; HUMANS; IMIDES; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE;

EID: 84055193785     PISSN: 00223263     EISSN: 15206904     Source Type: Journal    
DOI: 10.1021/jo2015054     Document Type: Article

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