Pleiotropic opioid regulation of spinal endomorphin 2 release and its adaptations to opioid withdrawal are sexually dimorphic

Journal of Pharmacology and Experimental Therapeutics

Volumn 340, Issue 1, 2012, Pages 56-63

  Chakrabarti, Sumita ^a   Liu, Nai Jiang ^a   Zadina, James E ^b   Sharma, Tarak ^a   Gintzler, Alan R ^a  

^a Downstate Health Sciences University   (United States)

^b TULANE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CHOLERA TOXIN; ENDOMORPHIN 2; G PROTEIN COUPLED RECEPTOR; MORPHINE; MU OPIATE RECEPTOR; OPIATE; PERTUSSIS TOXIN; PHOSPHOPROTEIN PHOSPHATASE 2A; PLACEBO; SUFENTANIL;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CHRONIC DRUG ADMINISTRATION; CONTROLLED STUDY; DRUG DOSE ESCALATION; DRUG WITHDRAWAL; ENZYME INHIBITION; FACILITATION; FEMALE; MALE; NONHUMAN; OPIOID WITHDRAWAL; PLEIOTROPY; PRIORITY JOURNAL; PROTEIN SECRETION; RAT; REGULATORY MECHANISM; SEX DIFFERENCE; SPINAL CORD;

ADAPTATION, PHYSIOLOGICAL; ANALGESICS, OPIOID; ANIMALS; BLOTTING, WESTERN; CHOLERA TOXIN; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDORPHINS; FEMALE; IMMUNOPRECIPITATION; MALE; MORPHINE; NARCOTIC ANTAGONISTS; OLIGOPEPTIDES; PERFUSION; PERTUSSIS TOXIN; PROTEIN PHOSPHATASE 2; RADIOIMMUNOASSAY; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, OPIOID, DELTA; RECEPTORS, OPIOID, KAPPA; RECEPTORS, OPIOID, MU; SEX CHARACTERISTICS; SPINE; SUBSTANCE WITHDRAWAL SYNDROME; SUFENTANIL;

EID: 84055177963     PISSN: 00223565     EISSN: 15210103     Source Type: Journal    
DOI: 10.1124/jpet.111.186874     Document Type: Article

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