Delayed enteral feeding impairs intestinal carbohydrate absorption in critically ill Patients

Critical Care Medicine

Volumn 40, Issue 1, 2012, Pages 50-54

  Nguyen, Nam Q ^a,b   Besanko, Laura K ^a   Burgstad, Carly ^a   Bellon, Max ^a   Holloway, Richard H ^a,b   Chapman, Marianne ^a,b   Horowitz, Michael ^b   Fraser, Robert J L ^a,b  

^a ROYAL ADELAIDE HOSPITAL   (Australia)

^b UNIVERSITY OF ADELAIDE   (Australia)

Author keywords

Critical illness; Delayed feeding; Enteral nutrition; Intestinal absorption

Indexed keywords

3 METHYLGLUCOSE; ENSURE; TECHNETIUM SULFUR COLLOID TC 99M;

ADOLESCENT; ADULT; AGED; ARTICLE; ARTIFICIAL VENTILATION; CARBOHYDRATE ABSORPTION; CLINICAL ARTICLE; CONTROLLED STUDY; CRITICALLY ILL PATIENT; ENTERIC FEEDING; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; INTENSIVE CARE UNIT; LENGTH OF STAY; MALE; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SMALL INTESTINE ABSORPTION; STOMACH EMPTYING; STOMACH SCINTISCANNING; THERAPY DELAY; VENTILATOR ASSOCIATED PNEUMONIA;

3-O-METHYLGLUCOSE; CARBOHYDRATE METABOLISM; CRITICAL ILLNESS; ENTERAL NUTRITION; FEMALE; HUMANS; INTESTINAL ABSORPTION; MALE; MIDDLE AGED; TIME FACTORS;

EID: 84055161210     PISSN: 00903493     EISSN: 15300293     Source Type: Journal    
DOI: 10.1097/CCM.0b013e31822d71a6     Document Type: Article

References (29)

1. Krishnan JA, Parce PB, Martinez A, et al: Caloric intake in medical ICU patients: Consistency of care with guidelines and relationship to clinical outcomes. Chest 2003; 124: 297-305
2. McClave SA, Sexton LK, Spain DA, et al: Enteral tube feeding in the intensive care unit: Factors impeding adequate delivery. Crit Care Med 1999; 27:1252-1256
3. De Beaux I, Chapman M, Fraser R, et al: Enteral nutrition in the critically ill: A prospective survey in an Australian intensive care unit. Anaesth Intensive Care 2001; 29: 619-622
4. De Jonghe B, Appere-De-Vechi C, Fournier M, et al: A prospective survey of nutritional support practices in intensive care unit patients: What is prescribed? What is delivered? Crit Care Med 2001; 29:8-12
5. Adam S, Batson S: A study of problems associated with the delivery of enteral feed in critically ill patients in five ICUs in the UK. Intensive Care Med 1997; 23:261-266
6. Chapman MJ, Besanko LK, Burgstad CM, et al Gastric emptying of a liquid nutrient meal in the critically ill: Relationship between scintigraphic and carbon breath test measurement. Gut 2011; Apr 17 [Epub ahead of print].
7. Corvilain B, Abramowicz M, Féry F, et al: Effect of short-term starvation on gastric emptying in humans: relationship to oral glucose tolerance. Am J Physiol 1995; 269: G512-G517
8. Nguyen NQ, Fraser RJ, Bryant LK, et al: The impact of delaying enteral feeding on gastric emptying, plasma cholecystokinin, and peptide YY concentrations in critically ill patients. Crit Care Med 2008; 36:1469-1474
9. Heyland DK, Dhaliwal R, Drover JW, et al: Canadian clinical practice guidelines for nutrition support in mechanically ventilated, critically ill adult patients. JPEN 2003; 27: 355-373
10. Artinian V, Krayem H, DiGiovine B: Effects of early enteral feeding on the outcome of critically ill mechanically ventilated medical patients. Chest 2006; 129:960-967
11. Levin RJ: Digestion and absorption of carbohydrates-from molecules and membranes to humans. Am J Clin Nutr 1994; 59:690S-698S.
12. Caspary WF: Physiology and pathophysiology of intestinal absorption. Am J Clin Nutr 1992; 55:299S-308S.
13. Alpers DH: Enteral feeding and gut atrophy. Cur Op Clin Nutr Metab Care 2002; 5:679-683
14. DeWitt RC, Kudsk KA: The gut's role in metabolism, mucosal barrier function, and gut immunology. Infect Dis Clin North Am 1999; 13:465-481
15. Stechmiller JK, Treloar D, Allen N: Gut dysfunction in critically ill patients: A review of the literature. Am J Crit Care 1997; 6:204-209
16. Mutlu GM, Mutlu EA, Factor P: GI complications in patients receiving mechanical ventilation. Chest 2001; 119:1222-1241
17. Buchman AL, Mestecky J, Moukarzel A, et al: Intestinal immune function is unaffected by parenteral nutrition in man. J Am Coll Nutr 1995; 14:656-661
18. Buchman AL, Moukarzel AA, Bhuta S, et al: Parenteral nutrition is associated with intestinal morphologic and functional changes in humans. JPEN 1995; 19:453-460
19. Hadfield RJ, Sinclair DG, Houldsworth PE, et al: Effects of enteral and parenteral nutrition on gut mucosal permeability in the critically ill. Am J Respir Crit Care Med 1995; 152: 1545-1548
20. Boullata J, Williams J, Cottrell F, et al: Accurate determination of energy needs in hospitalized patients. J Am Diet Assoc 2007; 107: 393-401
21. Deane AM, Nguyen NQ, Stevens JE, et al Endogenous glucagon-like peptide-1 slows gastric emptying in healthy subjects, attenuating postprandial glycemia. J Clin Endocrinol Metab 1995; 215-221
22. The Acute Respiratory Distress Syndrome Network: Ventilation with lower tidal volumes as compared with traditional tidal volumes for acute lung injury and the acute respiratory distress syndrome. N Engl J Med 2000; 342:1301-1308
23. Boza JJ, Möennoz D, Vuichoud J, et al: Food deprivation and refeeding influence growth, nutrient retention and functional recovery of rats. J Nutr 1999; 129:1340-1346
24. Hartke JL, Monaco MH, Wheeler MB, et al: Effect of a short-term fast on intestinal disaccharidase activity and villus morphology of piglets suckling insulin-like growth factor-I transgenic sows. J Anim Sci 2005; 83:2404-2413
25. Dworkin LD, Levine GM, Farber NJ, et al: Small intestinal mass of the rat is partially determined by indirect effects of intraluminal nutrition. Gastroenterology 1976; 71:626-630
26. Love AH: Metabolic response to malnutrition: Its relevance to enteral feeding. Gut 1986; 27:9-13
27. Grant JP: Anatomy and physiology of the luminal gut: Enteral access implications. JPEN 2006; 30:S41-S46
28. Chapman MJ, Fraser RJ, Matthews G, et al: Glucose absorption and gastric emptying in critical illness. Crit Care 2009; 13:R140
29. Meier-Hellmann A, Specht M, Hannemann L, et al: Splanchnic blood flow is greater in septic shock treated with norepinephrine than in severe sepsis. Intensive Care Med 1996; 22:1354-1359