The gut's role in metabolism, mucosal barrier function, and gut immunology

Infectious Disease Clinics of North America

Volumn 13, Issue 2, 1999, Pages 465-481

  DeWitt, R C ^a   Kudsk, K A ^a  

^a UNIVERSITY OF TENNESSEE HEALTH SCIENCE CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HUMORAL ANTIBODY;

B LYMPHOCYTE ACTIVATION; CRITICAL ILLNESS; ENTERIC FEEDING; GASTROINTESTINAL TRACT; GLYCOCALYX; HOST RESISTANCE; HUMAN; IMMUNE SYSTEM; INTESTINE ABSORPTION; INTESTINE ATRESIA; INTESTINE FLORA; INTESTINE MUCOSA; INTESTINE MUCOSA PERMEABILITY; LYMPHOID TISSUE; METABOLISM; NONHUMAN; NUTRIENT; PARENTERAL NUTRITION; REVIEW; SEPSIS; STRESS; T LYMPHOCYTE ACTIVATION;

EID: 0033037943     PISSN: 08915520     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5520(05)70086-6     Document Type: Article

References (156)

1. A.A. Adjei K. Yamauchi Y. Nakasone Arginine-supplemented diets inhibit endotoxin-induced bacterial translocation in mice Nutrition 11 1995 371
2. J.W. Alexander B.G. Macmillan J.D. Stinnett Beneficial effects of aggressive protein feeding in severely burned children Ann Surg 192 1980 505
3. J.C. Alverdy E. Aoys G.S. Moss Total parenteral nutrition promotes bacterial translocation from the gut Surgery 104 1988 185
4. J.A. Alverdy E. Aoys P. Weiss-Carrington The effect of glutamine-enriched TPN on gut immune cellularity J Surg Res 52 1992 34
5. J.W. Baker E.A. Deitch R.D. Berg Hemorrhagic shock induces bacterial translocation from the gut J Trauma 28 1988 896
6. J.G. Banwell R. Howard D. Cooper Intestinal microbial flora after feeding phytohemagglutinin lectins (Phaseolus vulgaris) to rats Appl Environ Microbiol 50 1985 68
7. A. Barbul S.A. Lazarou D.T. Efron Arginine enhances wound healing and lymphocyte immune responses in humans Surgery 108 1990 331
8. A. Barbul D.A. Sisto H.L. Wasserkrug Arginine stimulates lymphocyte immune response in healthy humans Surgery 90 1981 244
9. A. Barbul H.L. Wassserkrug E. Seifter Immunostimulatory effects of arginine in normal and injured rats J Surg Res 29 1980 228
10. R.G. Barton Nutrition support in critical illness Nutrition in Clinical Practice 9 1994 127
11. R.D. Berg Promotion of the translocation of enteric bacteria from the gastrointestinal tracts of mice by oral treatment with penicillin, clindamycin, or metronidazole Infect Immun 33 1981 854
12. P.Q. Bessey J.M. Watters T.T. Aoki Combined hormonal infusion simulates the metabolic response to injury Ann Surg 200 1984 264
13. T.R. Billiar P.E. Bankey B.A. Svingen Fatty acid intake and Kupffer cell function: Fish oil alters eicosanoid and monokine production to endotoxin stimulation Surgery 104 1988 343
14. S.B. Bittiner I. Cartwright W.F.G. Tucker A double-blind, randomized, placebo-controlled trial of fish oil in psoriasis Lancet 378 1988
15. G.L. Blackburn Nutrition and inflammatory events: Highly unsaturated fatty acids (ω-3 vs. ω-6) in surgical injury Proc Soc Exp Biol Med 200 1992 183
16. W. Bloom D.W. Fawcett Intestine Bloom W. Fawcett D.W. A Textbook of Histology ed 12 1994 WB Saunders Co. Philadelphia 616 651
17. R.H. Bower F.B. Cerra B. Bershadsky Early enteral administration of a formula (Impact®) supplemented with arginine, nucleotides, and fish oil in intensive care unit patients: Results of a multicenter, prospective, randomized, clinical trial Crit Care Med 23 1995 436
18. B. Boyer J.P. Thiery Epithelial cell adhesion mechanisms J Membr Biol 112 1989 97
19. P. Brandtzaeg T.S. Halstensen K. Kett Immunobiology and immunopathology of human gut mucosa: Humoral immunity and intraepithelial lymphocytes Gastroenterology 97 1989 1562
20. P. Brandtzaeg D.E. Nilssen T.O. Rognum Ontogeny of the mucosal immune system and IgA deficiency Gastroenterol Clin North Am 20 1991 397
21. O.G. Brooke A. Ashworth The influence of malnutrition on the postprandial metabolic rate and respiratory quotient Br J Nutr 27 1972 407
22. W.R. Brugge C.A. Burke Lactoferrin secretion in alcoholic pancreatic disease Dig Dis Sci 33 1988 178
23. A.L. Buchman A.A. Moukarzel S. Bhuta Parenteral nutrition is associated with intestinal morphologic and functional changes in humans JPEN J Parenter Enteral Nutr 19 1995 453
24. D.J. Burke J.A. Alverdy E. Aoys Glutamine-supplemented total parenteral nutrition improves gut immune function Arch Surg 124 1989 2396
25. E.A. Carter R.G. Tompkins J.G. Burke Cutaneous thermal injury alters macromolecular permeability of rat small intestine Surgery 107 1990 335
26. J.D. Carver W.I. Cax L.A. Barness Dietary nucleotides effects upon murine natural killer cell activity and macrophage activation JPEN J Parenter Enteral Nutr 14 1990 18
27. F.B. Cerra Hypermetabolism, organ failure, and metabolic support Surgery 92 1987 1
28. A. Chearelli G. Enzi A. Casadei Very early nutrition supplementation in burned patients Am J Clin Nutr 51 1990 1035
29. D.M. Chipman N. Sharon Mechanism of lysozyme action. Lysozyme is the first enzyme for which the relation between structure and function has become clear Science 165 1969 16
30. T.C.P. Curi M.P. Melo R.B. Azevedo Glutamine utilization by rat neutrophils Biochem Soc Trans 25 1997 249S
31. J.M. Daly M.D. Lieberman J. Goldfine Enteral nutrition with supplemental arginine, RNA, and omega-3 fatty acids in patients after operation: Immunologic, metabolic, and clinical outcome Surgery 112 1992 56
32. J.M. Daly F.N. Wintraub J. Shou Enteral nutrition during multimodality therapy in upper gastrointestinal cancer patients Ann Surg 221 1995 327
33. E.A. Deitch Intestinal permeability is increased in burn patients shortly after injury Surgery 107 1990 411
34. Dobbins W.O. III Human intestinal intraepithelial lymphocytes Gut 27 1986 972
35. R.G. Douglas J.H.F. Shaw Metabolic response to sepsis and trauma Br J Surg 76 1989 115
36. M.E.R. Dugan M.I. McBurney Luminal glutamine perfusion alters endotoxin-related changes in ileal permeability of the piglet JPEN J Parenter Enteral Nutr 19 1995 83
37. R.T. Ellison T.J. Giehl Killing of gram-negative bacteria by lactoferrin and lysozyme Journal of Clinical Investigation 88 1991 1080
38. W.C. Fanslow A.D. Kulkarni Van Buren C.T. Effect of nucleotide restriction and supplementation on resistance to experimental murine candidiasis JPEN J Parenter Enteral Nutr 12 1988 49
39. A. Ferguson Intraepithelial lymphocytes of the small intestine Gut 18 1977 921
40. S. Freier M. Eran J. Faber Effect of cholecystokinin and of its antagonist, of atropine, and of food on the release of immunoglobulin A and immunoglobulin G specific antibodies in the rat intestine Gastroenterology 93 1987 1242
41. T. Fujita K. Sakurai Efficacy of glutamine-enriched enteral nutrition in an experimental model of mucosal ulcerative colitis Br J Surg 82 1995 749
42. P. Fürst New parenteral substrates in clinical nutrition: Part 1. Introduction: New substrates in protein nutrition J Clin Nutr 48 1994 607
43. T. Ganz M.E. Selsted D. Szklarek Defensins. Natural peptide antibiotic of human neutophils J Clin Invest 76 1985 1427
44. A.J. Garber I.E. Karl D.M. Kipnis Alanine and glutamine synthesis and release from skeletal muscle. I: Glycolysis and amino acid release J Biol Chem 251 1976 826
45. L. Gianotti J.W. Alexander R. Gennan Oral glutamine decreases bacterial translocation, and improves survival in experimental gut-origin sepsis JPEN J Parenter Enteral Nutr 19 1995 69
46. L. Gianotti J.W. Alexander T. Pyles Arginine-supplemented diets improve survival in gut-derived sepsis and peritonitis by modulating bacterial clearance: The role of nitric oxide Ann Surg 217 1993 644
47. R.A. Gibbons Mucus of the mammalian genital tract Br Med Bull 34 1981 34
48. M.M. Gottschlich Selection of optimal lipid sources in enteral and parenteral nutrition Nutr Clin Pract 7 1992 152
49. M. Gottschlich M. Jenkins G. Warden Differential effects of three enteral dietary regimens on selected outcome variables in burn patients JPEN J Parenter Enteral Nutr 14 1990 225
50. B. Gumbiner The structure, biochemistry, and assembly of epithelial TJs Am J Physiol 253 1987 C749
51. 2 J Clin Invest 95 1995 603
52. J. Hegnhoj O.B. Muckadell An enzyme linked immunosorbent assay for measurements of lactoferrin in duodenal aspirates and other biological fluids Scand J Clin Lab Invest 45 1985 489
53. T.W. Hensle J. Askanazi Metabolism and nutrition in the perioperative period J Urol 139 1988 229
54. M.J. Heslin L. Latkany D. Leung A prospective, randomized trial of early enteral feeding after resection of upper gastrointestinal malignancy Ann Surg 226 1997 567 577
55. 3H into intestinal mucosal protein of protein-deprived rats J Clin Invest 48 1969 1224
56. S. Iijima T. Tsujinaka Y. Kido Intravenous administration of nucleosides and a nucleotide mixture diminishes intestinal mucosal atrophy induced by total parenteral nutrition JPEN J Parenter Enteral Nutr 17 1993 265
57. D.E. Jackson E.T. Lally M.D. Nakamura Migration of IgA-bearing lymphocytes into salivary glands Cell Immunol 63 1981 203
58. P.G. Janu K.A. Kudsk L. Jian Effects of bombesin on impairment of upper respiratory tract immunity induced by total parenteral nutrition Arch Surg 132 1997 89
59. G.L. Jensen E.A. Mascioli D.L. Seidner Parenteral infusion of long- and medium-chain triglycerides and reticuloendothelial system function in man JPEN J Parenter Enteral Nutr 14 1990 467
60. L.R. Johnson E.M. Copeland S.J. Dudrick Structural and hormonal alterations in the gastrointestinal tract of parenterally fed rats Gastroenterology 68 1975 1177
61. P. Jolles J. Jolles What's new in lysozyme research? Always a model system, today as yesterday Mol Cell Biochem 63 1984 165
62. D. Kaflkewitz A. Bendich Enzyme-induced asparagine and glutamine depletion and immune system function Am J Clin Nutr 37 1983 1025
63. J.R. Kalmar R.R. Arnold Killing of Actinobacillus actinomycetem commitans by human lactoferrin Infect Immun 56 1988 2552
64. T.D. Kane J.W. Alexander J.A. Johannigman The detection of microbial DNA in the blood: A sensitive method for diagnosing bacteremia and/or bacterial translocation in surgical patients Ann Surg 227 1998 1
65. T.D. Kane S.R. Johnson J.W. Alexander Detection of intestinal bacterial translocation using PCR J Surg Res 63 1996 59
66. M. Katayama X. Dazhong R.D. Specian Role of bacterial adherence and the mucus barrier on bacterial translocation: Effects of protein malnutrition and endotoxin in rats Ann Surg 225 1997 317
67. C.J. Kelly A. Cheung H. Gallagher Corticosterone and prostaglandin E2 inhibit perioperative natural killer cell cytotoxicity Surg Forum 44 1993 482
68. A.S. Kenler W.S. Swails D.R. Driscoll Early feeding in postsurgical cancer patients: Fish oil structured lipid-based polymeric formula vs a standard polymeric formula Ann Surg 223 1996 316
69. King BK, Kudsk KA, Li J, et al: Route and type of nutrition influence mucosal immunity to bacterial pneumonia. Ann Surg, in press
70. K.A. Kudsk G. Minard M.A. Croce A randomized trial of isonitrogenous enteral diets after severe trauma: An immune-enhancing diet reduces septic complications Ann Surg 224 1996 531
71. K.A. Kudsk M.A. Croce T.C. Fabian Enteral vs parenteral feeding: Effects on septic morbidity following blunt and penetrating trauma Ann Surg 215 1992 503 512
72. K.A. Kudsk J.M. Stone G. Carpenter Enteral and parenteral feeding influences morality after hemoglobin E. coli peritonitis in normal rats J Trauma 23 1983 605
73. A.D. Kulkarni W.C. Fanslow F.B. Rudolph Effect of dietary nucleotides on responses to bacterial infections JPEN J Parenter Enteral Nutr 10 1986 169
74. B. Langkamp-Henken T.B. Donovan L.M. Pate Increased intestinal permeability following blunt and penetrating trauma Crit Care Med 23 1995 660
75. B. Langkamp-Henken J. Glezer K.A. Kudsk Immunology of the gastrointestinal tract Nutrition in Clinical Practice 7 1992 100
76. A. Lee E. Gemmell Changes in the mouse intestinal microflora during weaning: Role of volatile fatty acids Infect Immun 5 1972 1
77. T.H. Lee R.L. Hoover J.D. Williams Effect of dietary enrichment with eicosapentaenoic and docosahexaenoic acids on in vitro neutrophil and monocyte leukotriene generation and neutrophil function N Engl J Med 312 1985 1217
78. G.J. Leitch A.D. Dickey I.A. Udezuler Entamoeba histolytica trophozoites in the lumen and mucus blanket of rat colons studied in vivo Infect Immun 47 1985 68
79. G.M. Levine J.J. Deren E. Steiger Role of oral intake in maintenance of gut mass and disaccharide activity Gastroenterology 67 1974 975
80. J. Li K.A. Kudsk B. Gocinski Effects of parenteral and enteral nutrition on gut-associated lymphoid tissue J Trauma 39 1995 44
81. J. Li K.A. Kudsk M. Hamidian Bombesin affects mucosal immunity and gut-associated lymphoid tissue in intravenously fed mice Arch Surg 130 1995 1164
82. J. Li K.A. Kudsk P. Janu Effect of glutamine-enriched total parenteral nutrition on small intestinal gut-associated lymphoid tissue and upper respiratory tract immunity Surgery 121 1996 542
83. C.L. Long J.M. Kinney J.W. Geiger Nonsuppressibility of gluconeogenesis by glucose in the septic patient Metabolism 25 1976 193
84. A.H.G. Love Metabolic response to malnutrition: Its relevance to enteral feeding Gut 27 suppl 1 1986 9
85. K.E. Magnusson I. Stjernstrom Mucosal barrier mechanisms. Interplay between secretory IgA (SigA), IgG and mucins on the surface properties and association of salmonellae with intestine and granulocytes Immunology 45 1982 239
86. J.C. Marshall J.C. Marshall N.V. Christou The gastrointestinal tract: The “undrained abscess” of multiple organ failure Ann Surg 218 3 1993 111
87. M.I. McHugh R. Wilkinson R.W. Elliott Immunosuppression with polyunsaturated fatty acids in renal transplantation Transplantation 24 1977 263
88. M.A. McNurlan P.J. Garlick Protein and amino acids in nutritional support Crit Care Clin 11 1995 635
89. S.N. Meydani Modulation of cytokine production by dietary polyunsaturated fatty acids Proc Soc Exp Biol Med 200 1992 189
90. S.N. Meydani S. Endres M.M. Woods Oral (n-3) fatty acid supplementation suppress cytokine production and lymphocyte proliferation: Comparison between young and older women J Nutr 121 1991 547
91. H. Mochizuki O. Trocki J.W. Alexander Mechanism of prevention of postburn hypermetabolism and catabolism by early enteral feeding Ann Surg 200 1984 297
92. F.A. Moore E.E. Moore K.A. Kudsk Clinical benefits of an immune-enhancing diet for early postinjury enteral feeding J Trauma 37 1994 607
93. F.A. Moore E.E. Moore T.N. Jones TEN vs TPN following major abdominal trauma: Reduced septic morbidity J Trauma 29 1989 916
94. F.A. Moore E.E. Moore T.N. Jones Benefits of immediate jejunostomy feeding after major abdominal trauma: A prospective, randomized study J Trauma 26 1986 874
95. F.D. Moore Energy and the maintenance of the body cell mass JPEN J Parenter Enteral Nutr 4 1980 228
96. G.A. Moore E.E. Moore R. Poggetti Gut bacterial translocation via the portal vein: A clinical perspective with major torso trauma J Trauma 31 1991 629
97. E.A. Newsholme D.P. Newsholme D. Phil A role for muscle in the immune system and its importance in surgery, trauma, sepsis, and burns Nutrition 4 1988 261
98. P. Newsholme R. Curi E.A. Newsholme Metabolism of glucose, glutamine, long-chain fatty acids and ketone bodies by murine macrophages Biochem J 239 1986 121
99. C.J. O'Boyle J. MacFie C.J. Mitchell Microbiology of bacterial translocation in humans Gut 42 1998 29
100. C.K. Ogle X. Guo Hasselgren P.-O. The gut as a source of inflammatory cytokines after stimulation with endotoxin Eur J Surg 163 1997 45
101. J.D. Oram B. Reiter Exhibition of bacteria by lactoferrin and other iron-chelating agents Biochim Biophys Acta 170 1968 351
102. C.A. Ottaway Neuroimmunomodulation in the intestinal mucosa Gastroenterol Clin North Am 20 1991 511
103. R.L. Owen Sequential uptake of horseradish peroxidase by lymphoid follicle epithelium of Peyer's patches in the normal unobstructed mouse intestine: An ultrastructural study Gastroenterology 72 1977 440
104. A. Panja L. Mayer Diversity and Function of Antigen-Presenting Cells in Mucosal Tissue Ogra P.L. Lamm M.E. McGhee J.R. Handbook of Mucosal Immunology 1994 Academic Press Inc. San Diego, CA 177
105. S.M. Pastores V. Kvetan D.P. Katz Immunomodulatory effects and therapeutic potential of glutamine in the critically ill surgical patient Nutrition 10 1994 385
106. M.D. Peck C.K. Ogle J.W. Alexander Composition of fat in enteral diets can influence outcome in experimental peritonitis Ann Surg 214 1990 74
107. T. Peeters G. Vantrappen The paneth cell: A source of intestinal lysozyme Gut 16 1975 553
108. D.A. Plumley W.W. Souba R.D. Hautamaki Accelerated lung amino acid release in hyperdynamic septic surgical patients Arch Surg 125 1990 57
109. H.A. Poret K.A. Kudsk M.A. Croce The effect of enteral feeding on catecholamine response following trauma Surg Forum 42 1991 11
110. E.M. Porter L. Liu A. Oren Localization of human intestinal defensin 5 in paneth cell granules Infect Immun 65 1997 2389
111. D. Powell Barrier function of epithelia Am J Physiol 241 1981 G275
112. G. Pulverer L. Ko J. Beuth Microflora-associated defense stimulation factors Scand J Gastroenterol 32 222 1997 107
113. S. Purandare K. Offenbartl B. Westrom Increased gut permeability to fluorescin isothiocyanate-dextran after total parenteral nutrition in the rat Scand J Gastroenterol 24 1989 678
114. Renegar K.B. Small P.A. Jr IgA mediation of murine nasal anti-influenza immunity J Virol 65 1991 2146
115. J.V. Reynolds S.M. Zhang A.K. Thom Arginine as an immunomodulator Surg Forum 38 1987 415
116. G.V. Richieri A.M. Kleinfeld Free fatty acids inhibit cytotoxic T lymphocyte-mediated lysis of allogeneic target cells J Immunol 145 1990 1074
117. C.B. Rodning I.D. Wilson S.L. Erlandsen Immunoglobulins within human small-intestinal paneth cells Lancet 1 1976 984
118. D. Rothman M.C. Latham W.A. Walker Transport of macromolecules in malnourished animals Nutr Res 2 1982 467
119. M.E. Rouz M. McWilliams J.M. Phillips-Quagliate Origin of IgA-secreting plasma cells in the mammary gland J Exp Med 146 1977 1311
120. K.R. Rozee D. Cooper K. Lam Microbial flora of the mouse ileum mucus layer and epithelial surface Appl Environ Microbiol 43 1982 1451
121. R. Rudzik R.L. Clancy D.Y.E. Perey Repopulation with IgA-containing cells of bronchial and intestinal lamina propria after transfer of homologous Peyer's patch and bronchial lymphocytes J Immunol 114 1975 1599
122. M. Salleh M. Ardawi E.A. Newsholme Glutamine metabolism in lymphocytes of the rat Biochem J 212 1983 835
123. M. Salmi S. Jalkanen Regulation of lymphocyte traffic to mucosal associated lymphatic tissue Gastroenterol Clin North Am 20 1991 495
124. D.L. Seidner E.A. Mascioli N.W. Istfan Effects of long-chain triglyceride emulsions on reticuloendothelial system function in humans JPEN J Parenter Enteral Nutr 13 1989 614
125. M.E. Shils Importance of Nutrition for Critically Ill Patients Zaloga G.P. Nutrition in Critical Care ed 1 1994 Mosby St Louis 3
126. E. Sonoda Y. Hitoshi N. Yamaguchi Differential regulation of IgA production by TGF-β and IL-5: TGF-β induces surface IgA-positive cells bearing IL-5 receptor, whereas IL-5 promotes their survival and maturation into IgA-secreting cells Cell Immunol 140 1992 158
127. W.W. Souba Glutamine: A key substrate for the splanchnic bed Annu Rev Nutr 11 1991 285
128. W.W. Souba K. Herskowitz V.S. Klimberg The effects of sepsis and endotoxemia on gut glutamine metabolism Ann Surg 211 1990 543
129. W.W. Souba R.J. Smith D.W. Wilmore Effect of glucocorticoids on glutamine metabolism in visceral organs Metabolism 34 1985 450
130. W.W. Souba D.W. Wilmore Postoperative alterations of arteriovenous exchange of amino acids across the gastrointestinal tract Surgery 94 1983 342
131. T. Soukka M. Lumikari T. Tenovuo Combined bactericidal effect of human lactoferrin and lysozyme against Streptococcus mutans serotype C Microbiol Ecol Health Dis 4 1991 259
132. Stanisz AM, Befus D, Bienenstock J: Differential effects of vasoactive intestinal peptide, substance P, and somatostatin on immunoglobulin synthesis and proliferations by lymphocytes from Peyer's patches, mesenteric lymph nodes, and spleen. J Immunol 136:152
133. M. Steiner H.R. Bouges L.S. Freeman Effect of starvation on tissue composition of the small intestine in the rat Am J Physiol 215 1968 75
134. T. Strasser S. Fischer P.C. Weber Leukotriene B5 is formed in human neutrophils after dietary supplementation with icosapentaenoic acid Proc Natl Acad Sci U S A 82 1985 1540
135. A. Strocchi M.D. Levitt A reappraisal of the magnitude and implications of the intestinal unstirred layer Gastroenterology 101 1991 843
136. C. Svanborg Bacterial adherence and mucosal immunity Ogra P.L. Lamm M.E. McGhee J.R. Handbook of Mucosal Immunology 1994 Academic Press San Diego, CA 71
137. C. Svanborg A.M. Svennerholm Secretory immunoglobulin A and G antibodies prevent adhesion of Escherichia coli to human urinary tract epithelial cells Infect Immun 22 3 1978 790
138. Van Buren C. A.D. Kulkarni W.C. Fanslow Dietary nucleotides, a requirement for helper/inducer T lymphocytes Transplantation 40 1985 694
139. van der Hulst R.R.W.J. von Meyenfeldt M.F. van Kreel B.K. Glutamine and the perservation of gut integrity Lancet 341 1993 1363
140. Van der Heijden P.J. W. Stok T.J. Bianchi Contribution of immunoglobulin-secreting cells in the murine small intestine to the `background' immunoglobulin production Immunology 62 1987 551
141. van der Waaij D. J.M. Berhuis-deVries Lekkerkerk-van der Wees J.E.C. Colonization resistance of the digestive tract in conventional and antibiotic treated mice J Hyg (Camb) 69 1971 405
142. van der Waaij D. J.M. Berhuis-deVries Lekkerkerk-van der Wees J.E.C. Colonization resistance of the digestive tract and the spread of bacteria to the lymphatic organs in mice J Hyg (Camb) 70 1972 335
143. van der Waaij D. J.M. Berhuis-deVries Lekkerkerk-van der Wees J.E.C. Colonization resistance of the digestive tract of mice during systemic antibiotic treatment J Hyg (Camb) 70 1972 605
144. P. Wachtler R. Axel W. Konig Influence of a preoperative enteral supplementation on functional activities of peripheral leukocytes from patients with major surgery Clin Nutr 14 1995 275
145. J.M.F. Wan M.P. Haw G.L. Blackburn Symposium of the interaction between nutrition and inflammation Proc Nutr Soc 48 1989 315
146. Wang Y.-B. H.U. Kloer Purification of human lysozyme from milk and pancreatic juice Anal Biochem 139 1985 224
147. D.W. Wilmore L.H. Aulick Systemic responses to injury and the healing wound JPEN J Parenter Enteral Nutr 4 1980 147
148. R.C. Williams R.J. Gibbons Inhibition of streptococcal attachment of receptors on human buccal epithelial cells by antigenically similar salivary glycoproteins Infect Immun 11 1975 711
149. H.G. Windmueller A.G. Spaeth Uptake and metabolism of plasma glutamine by the small intestine J Biol Chem 249 1974 5070
150. Winner L. III J. Mack R. Weltzin New model for analysis of mucosal immunity: Intestinal secretion of specific monoclonal immunoglobulin A from hybridoma tumors protects against Vibrio cholerae infection Infect Immun 59 1991 977
151. J.L. Wolf D.H. Rubin R. Finberg Intestinal M cells: A pathway for entry of reovirus into the host Science 212 1981 471
152. Y. Yao S. Bahrami G. Leichtfried Pathogenesis of hemorrhage-induced bacteria/endotoxin translocation in rats. Effects of recombinant bactericidal permeability-increasing protein Ann Surg 221 1995 398
153. S. Yoshida T. Yunoki K. Aoyagi Effect of glutamine supplement and hepatectomy on DNA and protein synthesis in the remnant liver J Surg Res 59 1995 475
154. C. Zhao I. Wang R.I. Lehrer Widespread expression of beta-defensin hBD-1 in human secretory glands and epithelial cells FEBS Lett 396 1996 319
155. V.A. Ziboh K.A. Cohen C.N. Ellis Effects of dietary supplementation of fish oil on neutrophil and epidermal fatty acids Arch Dermatol 122 1986 1277
156. T.R. Ziegler L.S. Young K. Benfell Clinical and metabolic efficacy of glutamine-supplemented parenteral nutrition after bone marrow transplantation: A randomized, double-blind, controlled study Ann Intern Med 116 1992 821