EBV-positive diffuse large B-cell lymphoma of the elderly with dual genotype and aberrant TIA-1 expression: A case report and review of literature

Journal of Hematopathology

Volumn 3, Issue 2, 2010, Pages 83-89

  Pongpruttipan, Tawatchai ^a   Treetipsatit, Jitsupa ^a   Amornpichetkul, Kanchana ^a   Kummalue, Tanawan ^a   Chuphrom, Anchalee ^a   Khuhapinant, Archrob ^a   Siritanaratkul, Noppadol ^a   Sukpanichnant, Sanya ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

Cytotoxic protein; Diffuse large B cell lymphoma; EBV; Immunoglobulin heavy chain gene; T cell receptor gene; TIA 1

Indexed keywords

EID: 83855163402     PISSN: None     EISSN: 18655785     Source Type: Journal    
DOI: 10.1007/s12308-010-0064-6     Document Type: Article

References (28)

1. Swerdlow HS, Campo E, Harris NL, Jaffe ES, Pileri SA, Stien H et al (2008) World Health Organization Classification of Tumours. Pathology and Genetics of Tumours of Haematopoietic and Lymphoid Tissues. IARC Press, Lyon, France.
2. Intragumtornchai T, Wannakrairoj P, Chaimongkol B, Bhoopat L, Lekhakula A, Thamprasit T et al (1996) Non-Hodgkin's lymphomas in Thailand. A retrospective pathologic and clinical analysis of 1391 cases. Cancer 78(8): 1813-1819.
3. Sukpanichnant S (2004) Analysis of 1983 cases of malignant lymphoma in Thailand according to the World Health Organization classification. Hum Pathol 35(2): 224-230.
4. Anderson P, Nagler-Anderson C, O'Brien C, Levine H, Watkins S, Slayter HS et al (1990) A monoclonal antibody reactive with a 15-kDa cytoplasmic granule-associated protein defines a subpopulation of CD8+ T lymphocytes. J Immunol 144(2): 574-582.
5. Forch P, Valcarcel J (2001) Molecular mechanisms of gene expression regulation by the apoptosis-promoting protein TIA-1. Apoptosis 6(6): 463-468.
6. Boulland ML, Kanavaros P, Wechsler J, Casiraghi O, Gaulard P (1997) Cytotoxic protein expression in natural killer cell lymphomas and in alpha beta and gamma delta peripheral T-cell lymphomas. J Pathol 183(4): 432-439.
7. Theriault C, Galoin S, Valmary S, Selves J, Lamant L, Roda D et al (2000) PCR analysis of immunoglobulin heavy chain (IgH) and TcR-gamma chain gene rearrangements in the diagnosis of lymphoproliferative disorders: results of a study of 525 cases. Mod Pathol 13(12): 1269-1279.
8. Garcia MJ, Martinez-Delgado B, Granizo JJ, Benitez J, Rivas C (2001) IgH, TCR-gamma, and TCR-beta gene rearrangement in 80 B- and T-cell non-Hodgkin's lymphomas: study of the association between proliferation and the so-called aberrant patterns. Diagn Mol Pathol 10(2): 69-77.
9. Svachova M, Tichy M (2008) PCR analysis of immunoglobulin heavy chain and TCR gene rearrangements in diagnosis of lymphoproliferative disorders on formalin-fixed, paraffin-embedded tissues. Neoplasma 55(1): 36-41.
10. Vergier B, Dubus P, Kutschmar A, Parrens M, Ferrer J, de Mascarel A et al (2002) Combined analysis of T cell receptor gamma and immunoglobulin heavy chain gene rearrangements at the single-cell level in lymphomas with dual genotype. J Pathol 198(2): 171-180.
11. van Dongen JJ, Langerak AW, Bruggemann M, Evans PA, Hummel M, Lavender FL et al (2003) Design and standardization of PCR primers and protocols for detection of clonal immunoglobulin and T-cell receptor gene recombinations in suspect lymphoproliferations: report of the BIOMED-2 Concerted Action BMH4-CT98-3936. Leukemia 17(12): 2257-2317.
12. Asano N, Yamamoto K, Tamaru J, Oyama T, Ishida F, Ohshima K et al (2009) Age-related Epstein-Barr virus (EBV)-associated B-cell lymphoproliferative disorders: comparison with EBV-positive classic Hodgkin lymphoma in elderly patients. Blood 113(12): 2629-2636.
13. Iuchi K, Aozasa K, Yamamoto S, Mori T, Tajima K, Minato K et al (1989) Non-Hodgkin's lymphoma of the pleural cavity developing from long-standing pyothorax. Summary of clinical and pathological findings in thirty-seven cases. Jpn J Clin Oncol 19(3): 249-257.
14. Cheuk W, Chan AC, Chan JK, Lau GT, Chan VN, Yiu HH (2005) Metallic implant-associated lymphoma: a distinct subgroup of large B-cell lymphoma related to pyothorax-associated lymphoma? Am J Surg Pathol 29(6): 832-836.
15. Mori N, Murakami YI, Shimada S, Iwamizu-Watanabe S, Yamashita Y, Hasegawa Y et al (2004) TIA-1 expression in hairy cell leukemia. Mod Pathol 17(7): 840-846.
16. Felgar RE, Macon WR, Kinney MC, Roberts S, Pasha T, Salhany KE (1997) TIA-1 expression in lymphoid neoplasms. Identification of subsets with cytotoxic T lymphocyte or natural killer cell differentiation. Am J Pathol 150(6): 1893-1900.
17. Kanavaros P, Vlychou M, Stefanaki K, Rontogianni D, Gaulard P, Pantelidaki E et al (1999) Cytotoxic protein expression in non-Hodgkin's lymphomas and Hodgkin's disease. Anticancer Res 19(2A): 1209-1216.
18. Nakamichi I, Takakuwa T, Tanio Y, Iuchi K, Aozasa K (2005) Pyothorax-associated lymphoma: an unusual case with both T- and B-cell genotypes. Virchows Arch 447(5): 888-891.
19. Griffiths GM, Mueller C (1991) Expression of perforin and granzymes in vivo: potential diagnostic markers for activated cytotoxic cells. Immunol Today 12(11): 415-419.
20. Salcedo TW, Azzoni L, Wolf SF, Perussia B (1993) Modulation of perforin and granzyme messenger RNA expression in human natural killer cells. J Immunol 151(5): 2511-2520.
21. Trapani JA, Smyth MJ (2002) Functional significance of the perforin/granzyme cell death pathway. Nat Rev Immunol 2(10): 735-747.
22. Pardo J, Aguilo JI, Anel A, Martin P, Joeckel L, Borner C et al (2009) The biology of cytotoxic cell granule exocytosis pathway: granzymes have evolved to induce cell death and inflammation. Microbes Infect 11(4): 452-459.
23. Chavez-Galan L, Arenas-Del Angel MC, Zenteno E, Chavez R, Lascurain R (2009) Cell death mechanisms induced by cytotoxic lymphocytes. Cell Mol Immunol 6(1): 15-25.
24. Medley QG, Kedersha N, O'Brien S, Tian Q, Schlossman SF, Streuli M et al (1996) Characterization of GMP-17, a granule membrane protein that moves to the plasma membrane of natural killer cells following target cell recognition. Proc Natl Acad Sci USA 93(2): 685-689.
25. Beaubier NT, Hart AP, Bartolo C, Willman CL, Viswanatha DS (2000) Comparison of capillary electrophoresis and polyacrylamide gel electrophoresis for the evaluation of T and B cell clonality by polymerase chain reaction. Diagn Mol Pathol 9(3): 121-131.
26. Vega F, Medeiros LJ, Jones D, Abruzzo LV, Lai R, Manning J et al (2001) A novel four-color PCR assay to assess T-cell receptor gamma gene rearrangements in lymphoproliferative lesions. Am J Clin Pathol 116(1): 17-24.
27. Tang MB, Chong TK, Tan ES, Sun YJ, Tan SH (2008) A comparative study of polymerase chain reaction detection of clonal T-cell receptor gamma chain gene rearrangements using polyacrylamide gel electrophoresis versus fluorescence capillary electrophoresis. Ann Acad Med Singapore 37(1): 27-31.
28. Hollingsworth HC, Stetler-Stevenson M, Gagneten D, Kingma DW, Raffeld M, Jaffe ES (1994) Immunodeficiency-associated malignant lymphoma. Three cases showing genotypic evidence of both T- and B-cell lineages. Am J Surg Pathol 18(11): 1092-1101.