The high dielectric constant of staphylococcal nuclease is encoded in its structural architecture

Journal of the American Chemical Society

Volumn 133, Issue 50, 2011, Pages 20072-20075

  Goh, Garrett B ^a   García Moreno E , Bertrand ^b   Brooks, Charles L ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APPARENT DIELECTRIC CONSTANT; ELECTROSTATIC CALCULATIONS; FIRST-PRINCIPLES; HIGH DIELECTRIC CONSTANTS; MICROENVIRONMENTS; MUTATION SITES; SPATIAL DEPENDENCE; STAPHYLOCOCCAL NUCLEASE; STRUCTURAL ARCHITECTURE; STRUCTURAL REORGANIZATION;

CHEMISTRY; SYNTHESIS (CHEMICAL);

ELECTROSTATICS;

ASPARTIC ACID; BACTERIAL ENZYME; GLUTAMIC ACID; LYSINE; NUCLEASE;

ARTICLE; CRYSTAL STRUCTURE; DIELECTRIC CONSTANT; ENZYME STRUCTURE; GENE MUTATION; IONIZATION; MICROENVIRONMENT; NONHUMAN; PKA; STAPHYLOCOCCUS; STATIC ELECTRICITY; WILD TYPE;

CRYSTALLOGRAPHY, X-RAY; ELECTRICITY; MICROCOCCAL NUCLEASE; PROTEIN CONFORMATION;

EID: 83755168879     PISSN: 00027863     EISSN: 15205126     Source Type: Journal    
DOI: 10.1021/ja2084866     Document Type: Article

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