Octreotide-modified and pH-triggering polymeric micelles loaded with doxorubicin for tumor targeting delivery

European Journal of Pharmaceutical Sciences

Volumn 45, Issue 1-2, 2012, Pages 216-226

  Niu, Jiangxiu ^a,b   Su, Zhigui ^a   Xiao, Yanyu ^a   Huang, Aiwen ^a,c   Li, Hongying ^a   Bao, Xiao ^a   Li, Sai ^a   Chen, Yinan ^a   Sun, Mingjie ^a   Ping, Qineng ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b HUANGSHAN UNIVERSITY   (China)

^c FUZHOU GENERAL HOSPITAL   (China)

Author keywords

Long circulation; Micelles; Octreotide mediated endocytosis; pH sensitivity; Targeting delivery

Indexed keywords

AMPHOPHILE; CARBOXYL GROUP; CHITOSAN; DOXORUBICIN; MACROGOL STEARATE; OCTREOTIDE; OCTREOTIDE POLYETHYLENE GLYCOL MONOSTEARATE; PLASMA PROTEIN; POLYMER; SOMATOSTATIN RECEPTOR; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ARTICLE; CRITICAL MICELLE CONCENTRATION; DRUG TARGETING; ENCAPSULATION; ENDOCYTOSIS; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MICELLE; NONHUMAN; PARTICLE SIZE; PH; PRIORITY JOURNAL; PROTON TRANSPORT; RAT; ZETA POTENTIAL;

ANIMALS; ANTIBIOTICS, ANTINEOPLASTIC; ANTINEOPLASTIC AGENTS, HORMONAL; CELL LINE, TUMOR; CHITOSAN; DOXORUBICIN; DRUG CARRIERS; DRUG COMPOUNDING; DRUG STABILITY; HYDROGEN-ION CONCENTRATION; HYDROPHOBIC AND HYDROPHILIC INTERACTIONS; MALE; MICELLES; NEOPLASMS; OCTREOTIDE; PHYSICOCHEMICAL PHENOMENA; POLYETHYLENE GLYCOLS; POLYMERS; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SPECIFIC PATHOGEN-FREE ORGANISMS;

EID: 83655167397     PISSN: 09280987     EISSN: 18790720     Source Type: Journal    
DOI: 10.1016/j.ejps.2011.11.013     Document Type: Article

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