메뉴 건너뛰기




Volumn 75, Issue 1, 2012, Pages 24-29

STAT3 expression in activating EGFR-driven adenocarcinoma of the lung

Author keywords

Adenocarcinoma; Bronchioloalveolar carcinoma; EGFR; JAK2; Non small cell lung cancer; STAT3

Indexed keywords

MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE B; STAT3 PROTEIN; VASCULOTROPIN RECEPTOR;

EID: 83555174457     PISSN: 01695002     EISSN: 18728332     Source Type: Journal    
DOI: 10.1016/j.lungcan.2011.05.015     Document Type: Article
Times cited : (16)

References (28)
  • 1
    • 57349182464 scopus 로고    scopus 로고
    • Annual report to the nation on the status of cancer, 1975-2005, featuring trends in lung cancer, tobacco use, and tobacco control
    • Jemal A., Thun M.J., Ries L.A., Howe H.L., Weir H.K., Center M.M., et al. Annual report to the nation on the status of cancer, 1975-2005, featuring trends in lung cancer, tobacco use, and tobacco control. J Natl Cancer Inst 2008, 100:1672-1694.
    • (2008) J Natl Cancer Inst , vol.100 , pp. 1672-1694
    • Jemal, A.1    Thun, M.J.2    Ries, L.A.3    Howe, H.L.4    Weir, H.K.5    Center, M.M.6
  • 2
    • 70049112736 scopus 로고    scopus 로고
    • Revisiting stage IIIB and IV non-small cell lung cancer: analysis of the surveillance, epidemiology, and end results data
    • William W.N., Lin H.Y., Lee J.J., Lippman S.M., Roth J.A., Kim E.S. Revisiting stage IIIB and IV non-small cell lung cancer: analysis of the surveillance, epidemiology, and end results data. Chest 2009.
    • (2009) Chest
    • William, W.N.1    Lin, H.Y.2    Lee, J.J.3    Lippman, S.M.4    Roth, J.A.5    Kim, E.S.6
  • 3
    • 0028724152 scopus 로고
    • Atypical alveolar hyperplasia: relationship with pulmonary adenocarcinoma, p53, and c-erbB-2 expression
    • Kerr K.M., Carey F.A., King G., Lamb D. Atypical alveolar hyperplasia: relationship with pulmonary adenocarcinoma, p53, and c-erbB-2 expression. J Pathol 1994, 174:249-256.
    • (1994) J Pathol , vol.174 , pp. 249-256
    • Kerr, K.M.1    Carey, F.A.2    King, G.3    Lamb, D.4
  • 4
    • 1542314217 scopus 로고    scopus 로고
    • Correlation between computed tomographic findings, bronchioloalveolar carcinoma component, and biologic behavior of small-sized lung adenocarcinomas
    • Okada M., Nishio W., Sakamoto T., Uchino K., Hanioka K., Ohbayashi C., et al. Correlation between computed tomographic findings, bronchioloalveolar carcinoma component, and biologic behavior of small-sized lung adenocarcinomas. J Thorac Cardiovasc Surg 2004, 127:857-861.
    • (2004) J Thorac Cardiovasc Surg , vol.127 , pp. 857-861
    • Okada, M.1    Nishio, W.2    Sakamoto, T.3    Uchino, K.4    Hanioka, K.5    Ohbayashi, C.6
  • 5
    • 0029063625 scopus 로고
    • Small adenocarcinoma of the lung. Histologic characteristics and prognosis
    • Noguchi M., Morikawa A., Kawasaki M., Matsuno Y., Yamada T., Hirohashi S., et al. Small adenocarcinoma of the lung. Histologic characteristics and prognosis. Cancer 1995, 75:2844-2852.
    • (1995) Cancer , vol.75 , pp. 2844-2852
    • Noguchi, M.1    Morikawa, A.2    Kawasaki, M.3    Matsuno, Y.4    Yamada, T.5    Hirohashi, S.6
  • 7
    • 21144474588 scopus 로고    scopus 로고
    • Evolving concepts in the pathology and computed tomography imaging of lung adenocarcinoma and bronchioloalveolar carcinoma
    • Travis W.D., Garg K., Franklin W.A., Wistuba I.I., Sabloff B., Noguchi M., et al. Evolving concepts in the pathology and computed tomography imaging of lung adenocarcinoma and bronchioloalveolar carcinoma. J Clin Oncol 2005, 23:3279-3287.
    • (2005) J Clin Oncol , vol.23 , pp. 3279-3287
    • Travis, W.D.1    Garg, K.2    Franklin, W.A.3    Wistuba, I.I.4    Sabloff, B.5    Noguchi, M.6
  • 8
    • 35548962203 scopus 로고    scopus 로고
    • Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer
    • Mitsudomi T., Yatabe Y. Mutations of the epidermal growth factor receptor gene and related genes as determinants of epidermal growth factor receptor tyrosine kinase inhibitors sensitivity in lung cancer. Cancer Sci 2007, 98:1817-1824.
    • (2007) Cancer Sci , vol.98 , pp. 1817-1824
    • Mitsudomi, T.1    Yatabe, Y.2
  • 9
    • 33744814638 scopus 로고    scopus 로고
    • Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors
    • Politi K., Zakowski M.F., Fan P.D., Schonfeld E.A., Pao W., Varmus H.E. Lung adenocarcinomas induced in mice by mutant EGF receptors found in human lung cancers respond to a tyrosine kinase inhibitor or to down-regulation of the receptors. Genes Dev 2006, 20:1496-1510.
    • (2006) Genes Dev , vol.20 , pp. 1496-1510
    • Politi, K.1    Zakowski, M.F.2    Fan, P.D.3    Schonfeld, E.A.4    Pao, W.5    Varmus, H.E.6
  • 10
    • 33744788136 scopus 로고    scopus 로고
    • The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies
    • Ji H., Li D., Chen L., Shimamura T., Kobayashi S., McNamara K., et al. The impact of human EGFR kinase domain mutations on lung tumorigenesis and in vivo sensitivity to EGFR-targeted therapies. Cancer Cell 2006, 9:485-495.
    • (2006) Cancer Cell , vol.9 , pp. 485-495
    • Ji, H.1    Li, D.2    Chen, L.3    Shimamura, T.4    Kobayashi, S.5    McNamara, K.6
  • 11
    • 50149108795 scopus 로고    scopus 로고
    • Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter
    • Ohashi K., Rai K., Fujiwara Y., Osawa M., Hirano S., Takata K., et al. Induction of lung adenocarcinoma in transgenic mice expressing activated EGFR driven by the SP-C promoter. Cancer Sci 2008, 99:1747-1753.
    • (2008) Cancer Sci , vol.99 , pp. 1747-1753
    • Ohashi, K.1    Rai, K.2    Fujiwara, Y.3    Osawa, M.4    Hirano, S.5    Takata, K.6
  • 12
    • 34548509720 scopus 로고    scopus 로고
    • Mutation of the epidermal growth factor receptor gene in the development of adenocarcinoma of the lung
    • Kozuki T., Hisamoto A., Tabata M., Takigawa N., Kiura K., Segawa Y., et al. Mutation of the epidermal growth factor receptor gene in the development of adenocarcinoma of the lung. Lung Cancer 2007, 58:30-35.
    • (2007) Lung Cancer , vol.58 , pp. 30-35
    • Kozuki, T.1    Hisamoto, A.2    Tabata, M.3    Takigawa, N.4    Kiura, K.5    Segawa, Y.6
  • 13
    • 0037192781 scopus 로고    scopus 로고
    • Transcriptional stimulation of the surfactant protein B gene by STAT3 in respiratory epithelial cells
    • Yan C., Naltner A., Martin M., Naltner M., Fangman J.M., Gurel O. Transcriptional stimulation of the surfactant protein B gene by STAT3 in respiratory epithelial cells. J Biol Chem 2002, 277:10967-10972.
    • (2002) J Biol Chem , vol.277 , pp. 10967-10972
    • Yan, C.1    Naltner, A.2    Martin, M.3    Naltner, M.4    Fangman, J.M.5    Gurel, O.6
  • 15
    • 33645506849 scopus 로고    scopus 로고
    • Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor
    • Alvarez J.V., Greulich H., Sellers W.R., Meyerson M., Frank D.A. Signal transducer and activator of transcription 3 is required for the oncogenic effects of non-small-cell lung cancer-associated mutations of the epidermal growth factor receptor. Cancer Res 2006, 66:3162-3168.
    • (2006) Cancer Res , vol.66 , pp. 3162-3168
    • Alvarez, J.V.1    Greulich, H.2    Sellers, W.R.3    Meyerson, M.4    Frank, D.A.5
  • 16
    • 0037444373 scopus 로고    scopus 로고
    • Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice
    • Blaskovich M.A., Sun J., Cantor A., Turkson J., Jove R., Sebti S.M. Discovery of JSI-124 (cucurbitacin I), a selective Janus kinase/signal transducer and activator of transcription 3 signaling pathway inhibitor with potent antitumor activity against human and murine cancer cells in mice. Cancer Res 2003, 63:1270-1279.
    • (2003) Cancer Res , vol.63 , pp. 1270-1279
    • Blaskovich, M.A.1    Sun, J.2    Cantor, A.3    Turkson, J.4    Jove, R.5    Sebti, S.M.6
  • 17
    • 4444332925 scopus 로고    scopus 로고
    • Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer
    • Cappuzzo F., Magrini E., Ceresoli G.L., Bartolini S., Rossi E., Ludovini V., et al. Akt phosphorylation and gefitinib efficacy in patients with advanced non-small-cell lung cancer. J Natl Cancer Inst 2004, 96:1133-1141.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 1133-1141
    • Cappuzzo, F.1    Magrini, E.2    Ceresoli, G.L.3    Bartolini, S.4    Rossi, E.5    Ludovini, V.6
  • 18
    • 31544459265 scopus 로고    scopus 로고
    • Detection of EGFR gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay
    • Asano H., Toyooka S., Tokumo M., Ichimura K., Aoe K., Ito S., et al. Detection of EGFR gene mutation in lung cancer by mutant-enriched polymerase chain reaction assay. Clin Cancer Res 2006, 12:43-48.
    • (2006) Clin Cancer Res , vol.12 , pp. 43-48
    • Asano, H.1    Toyooka, S.2    Tokumo, M.3    Ichimura, K.4    Aoe, K.5    Ito, S.6
  • 19
    • 0021061819 scopus 로고
    • Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays
    • Mosmann T. Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays. J Immunol Methods 1983, 65:55-63.
    • (1983) J Immunol Methods , vol.65 , pp. 55-63
    • Mosmann, T.1
  • 20
    • 28544438023 scopus 로고    scopus 로고
    • Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer
    • Haura E.B., Zheng Z., Song L., Cantor A., Bepler G. Activated epidermal growth factor receptor-Stat-3 signaling promotes tumor survival in vivo in non-small cell lung cancer. Clin Cancer Res 2005, 11:8288-8294.
    • (2005) Clin Cancer Res , vol.11 , pp. 8288-8294
    • Haura, E.B.1    Zheng, Z.2    Song, L.3    Cantor, A.4    Bepler, G.5
  • 21
    • 36849012237 scopus 로고    scopus 로고
    • Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas
    • Gao S.P., Mark K.G., Leslie K., Pao W., Motoi N., Gerald W.L., et al. Mutations in the EGFR kinase domain mediate STAT3 activation via IL-6 production in human lung adenocarcinomas. J Clin Invest 2007, 117:3846-3856.
    • (2007) J Clin Invest , vol.117 , pp. 3846-3856
    • Gao, S.P.1    Mark, K.G.2    Leslie, K.3    Pao, W.4    Motoi, N.5    Gerald, W.L.6
  • 22
    • 34548785120 scopus 로고    scopus 로고
    • Activation of the signal transducers and activators of the transcription 3 pathway in alveolar epithelial cells induces inflammation and adenocarcinomas in mouse lung
    • Li Y., Du H., Qin Y., Roberts J., Cummings O.W., Yan C. Activation of the signal transducers and activators of the transcription 3 pathway in alveolar epithelial cells induces inflammation and adenocarcinomas in mouse lung. Cancer Res 2007, 67:8494-8503.
    • (2007) Cancer Res , vol.67 , pp. 8494-8503
    • Li, Y.1    Du, H.2    Qin, Y.3    Roberts, J.4    Cummings, O.W.5    Yan, C.6
  • 23
    • 34548710844 scopus 로고    scopus 로고
    • Expression of activated and latent signal transducer and activator of transcription 3 in 303 non-small cell lung carcinomas and 44 malignant mesotheliomas: possible role for chemotherapeutic intervention
    • Achcar Rde O., Cagle P.T., Jagirdar J. Expression of activated and latent signal transducer and activator of transcription 3 in 303 non-small cell lung carcinomas and 44 malignant mesotheliomas: possible role for chemotherapeutic intervention. Arch Pathol Lab Med 2007, 131:1350-1360.
    • (2007) Arch Pathol Lab Med , vol.131 , pp. 1350-1360
    • Achcar Rde, O.1    Cagle, P.T.2    Jagirdar, J.3
  • 24
    • 0037699512 scopus 로고    scopus 로고
    • Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells
    • Song L., Turkson J., Karras J.G., Jove R., Haura E.B. Activation of Stat3 by receptor tyrosine kinases and cytokines regulates survival in human non-small cell carcinoma cells. Oncogene 2003, 22:4150-4165.
    • (2003) Oncogene , vol.22 , pp. 4150-4165
    • Song, L.1    Turkson, J.2    Karras, J.G.3    Jove, R.4    Haura, E.B.5
  • 25
    • 63549094156 scopus 로고    scopus 로고
    • Epidermal growth factor receptor mutations in non-small cell lung cancer influence downstream Akt, MAPK and Stat3 signaling
    • Zimmer S., Kahl P., Buhl T.M., Steiner S., Wardelmann E., Merkelbach-Bruse S., et al. Epidermal growth factor receptor mutations in non-small cell lung cancer influence downstream Akt, MAPK and Stat3 signaling. J Cancer Res Clin Oncol 2009, 135:723-730.
    • (2009) J Cancer Res Clin Oncol , vol.135 , pp. 723-730
    • Zimmer, S.1    Kahl, P.2    Buhl, T.M.3    Steiner, S.4    Wardelmann, E.5    Merkelbach-Bruse, S.6
  • 26
    • 60549106882 scopus 로고    scopus 로고
    • Whole genome comparison of allelic imbalance between noninvasive and invasive small-sized lung adenocarcinomas
    • Nakanishi H., Matsumoto S., Iwakawa R., Kohno T., Suzuki K., Tsuta K., et al. Whole genome comparison of allelic imbalance between noninvasive and invasive small-sized lung adenocarcinomas. Cancer Res 2009, 69:1615-1623.
    • (2009) Cancer Res , vol.69 , pp. 1615-1623
    • Nakanishi, H.1    Matsumoto, S.2    Iwakawa, R.3    Kohno, T.4    Suzuki, K.5    Tsuta, K.6
  • 27
    • 67650828139 scopus 로고    scopus 로고
    • JAK2 inhibitors: not the next imatinib but researchers see other possibilities
    • Garber K. JAK2 inhibitors: not the next imatinib but researchers see other possibilities. J Natl Cancer Inst 2009, 101:980-982.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 980-982
    • Garber, K.1
  • 28
    • 62449283132 scopus 로고    scopus 로고
    • Sustained Src inhibition results in signal transducer and activator of transcription 3 (STAT3) activation and cancer cell survival via altered Janus-activated kinase-STAT3 binding
    • Sen B., Saigal B., Parikh N., Gallick G., Johnson F.M. Sustained Src inhibition results in signal transducer and activator of transcription 3 (STAT3) activation and cancer cell survival via altered Janus-activated kinase-STAT3 binding. Cancer Res 2009, 69:1958-1965.
    • (2009) Cancer Res , vol.69 , pp. 1958-1965
    • Sen, B.1    Saigal, B.2    Parikh, N.3    Gallick, G.4    Johnson, F.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.