Overexpression of interleukin-6 and -8, cell growth inhibition and morphological changes in 2-hydroxyethyl methacrylate-treated human dental pulp mesenchymal stem cells

International Endodontic Journal

Volumn 45, Issue 1, 2012, Pages 19-25

  Trubiani, O ^a   Cataldi, A ^a   De Angelis, F ^a   D'Arcangelo, C ^a   Caputi, S ^a  

^a UNIVERSITY OF CHIETI   (Italy)

Author keywords

2 hydroxyethyl methacrylate; Dental pulp mesenchymal stem cells; Interleukin 6; Interleukin 8

Indexed keywords

2 HYDROXYETHYL METHACRYLATE; BIOMEDICAL AND DENTAL MATERIALS; COLORING AGENT; DIAGNOSTIC AGENT; IL6 PROTEIN, HUMAN; IL8 PROTEIN, HUMAN; INTERLEUKIN 6; INTERLEUKIN 8; METHACRYLIC ACID DERIVATIVE; TETRAZOLIUM; THIAZOLE DERIVATIVE; THIAZOLYL BLUE; TRYPAN BLUE;

ADOLESCENT; ARTICLE; CELL GRANULE; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; CULTURE TECHNIQUE; CYTOLOGY; DOSE RESPONSE; DRUG EFFECT; GENE EXPRESSION REGULATION; HUMAN; MESENCHYMAL STEM CELL; SECRETION; TIME; TOOTH PULP;

ADOLESCENT; CELL CULTURE TECHNIQUES; CELL PROLIFERATION; CELL SHAPE; CELL SURVIVAL; COLORING AGENTS; CYTOPLASMIC GRANULES; DENTAL MATERIALS; DENTAL PULP; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; HUMANS; INTERLEUKIN-6; INTERLEUKIN-8; MESENCHYMAL STEM CELLS; METHACRYLATES; TETRAZOLIUM SALTS; THIAZOLES; TIME FACTORS; TRYPAN BLUE;

EID: 83555164786     PISSN: 01432885     EISSN: 13652591     Source Type: Journal    
DOI: 10.1111/j.1365-2591.2011.01942.x     Document Type: Article

References (24)

1. Abebe W, Maddux WF, Schuster GS, Lewis JB (2003) Vascular responsiveness to dimethylaminoethyl methacrylate and its degradation products. Journal of Biomedical Materials Research. Part A 66, 155-61.
2. About I, Bottero MJ, de Denato P, Camps J, Franquin JC, Mitsiadis TA (2000) Human dentin production in vitro. Experimental Cell Research 258, 33-41.
3. Becher R, Kopperud HM, Al RH et al. (2006) Pattern of cell death after in vitro exposure to GDMA, TEGDMA, HEMA and two compomer extracts. Dental Materials 22, 630-40.
4. Cehreli ZC, Turgut M, Olmez S, Dagdeviren A, Atilla P (2000) Short-term human primary pulpal response after direct pulp capping with fourth-generation dentin adhesives. Journal of Clinical Pediatric Dentistry 25, 65-71.
5. Chang HH, Guo MK, Kasten FH et al. (2005) Stimulation of glutathione depletion, ROS production and cell cycle arrest of dental pulp cells and gingival epithelial cells by HEMA. Biomaterials 26, 745-53.
6. Couble ML, Farges JC, Bleicher F, Perrat-Mabillon B, Boudeulle M, Magloire H. (2000) Odontoblast differentiation of human dental pulp cells in explant cultures. Calcified Tissue International 66, 129-38.
7. Dominici M, Le Blanc K, Mueller I et al. (2006) Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. Cytotherapy 8, 315-7.
8. Geurtsen W, Spahl W, Leyhausen G. (1998) Residual monomer/additive release and variability in cytotoxicity of light-curing glass-ionomer cements and compomers. Journal of Dental Research 77, 2012-9.
9. Geurtsen W, Spahl W, Müller K, Leyhausen G. (1999) Aqueous extracts from dentin adhesives contain cytotoxic chemicals. Journal of Biomedical Materials Research 48, 772-7.
10. Goldberg M (2008) In vitro and in vivo studies on the toxicity of dental resin components: a review. Clinical Oral Investigations 12, 1-8.
11. Hanks CT, Strawn SE, Wataha JC, Craig RG (1991) Cytotoxic effects of resin components on cultured mammalian fibroblasts. Journal of Dental Research 70, 1450-5.
12. Heinrich PC, Behrmann I, Haan S, Hermanns HM, Müller-Newen G, Schaper F. (2003) Principles of interleukin (IL)-6-type cytokine signalling and its regulation. Biochemical Journal 374, 1-20.
13. Kitasako Y, Inokoshi S, Tagami J (1999) Effects of direct resin capping techniques on short term mechanically exposed pulps. Journal of Dentistry 27, 257-63.
14. Kleinsasser NH, Schmid K, Sassen AW et al. (2006) Cytotoxic and genotoxic effects of resin monomers in human salivary gland tissue and lymphocytes as assessed by the single cell microgel electrophoresis (Comet) assay. Biomaterials 27, 1762-70.
15. Lee DH, Kim NR, Lim BS, Lee YK, Yang HC. (2009) Effects of TEGDMA and HEMA on the expression of COX-2 and iNOS in cultured murine macrophage cells. Dental Materials 25, 240-6.
16. Nasser MW, Raghuwanshi SK, Grant DJ, Jala VR, Rajarathnam K, Richardson RM (2009) Differential activation and regulation of CXCR1 and CXCR2 by CXCL8 monomer and dimer. The Journal of Immunology 183, 3425-32.
17. Nicholson JW, Czarnecka B (2008) The biocompatibility of resin-modified glass-ionomer cements for dentistry. Dental Materials 24, 1702-8.
18. Souza NJ, Justo GZ, Oliveira CR, Haun M, Bincoletto C (2006) Cytotoxicity of materials used in perforation repair tested using the V79 fibroblast cell line and the granulocyte-macrophage progenitor cells. International Endodontic Journal 39, 40-7.
19. Trubiani O, D'Arcangelo C, Di Iorio D, Di Nardo Di Maio F, Caputi S (2007) Dental pulp stem cells bioadhesivity: evaluation on mineral-trioxide-aggregate. International Journal of Immunopathology and Pharmacology 20(Suppl 1), 81-6.
20. Trubiani O, Isgro A, Zini N et al. (2008) Functional interleukin-7/interleukin-7Ralpha, and SDF-1alpha/CXCR4 are expressed by human periodontal ligament derived mesenchymal stem cells. Journal of Cellular Physiology 214, 706-13.
21. Trubiani O, Caputi S, Di Iorio D et al. (2010) The cytotoxic effects of resin-based sealers on dental pulp stem cells. International Endodontic Journal 43, 646-53.
22. Tsukamoto H, Nagasawa K, Ueda Y et al. (1992) Effects of cell differentiation on the synthesis of the third and fourth component of complement (C3, C4) by the human monocytic cell line U937. Immunology 77, 621-3.
23. Vane JR, Bakhle YS, Botting RM. (1998) Cyclooxygenases 1 and 2. Annual Review of Pharmacology and Toxicology 38, 97-120.
24. Zuk PA, Zhu M, Mizuno H et al. (2001) Multilineage cells from human adipose tissue: implications for cell-based therapies. Tissue Engineering 7, 211-28.