IL-33 - A cytokine which balances on a knife's edge?

Journal of Hepatology

Volumn 56, Issue 1, 2012, Pages 7-10

  Erhardt, Annette ^a   Tiegs, Gisa ^a  

^a UNIVERSITY MEDICAL CENTER HAMBURG EPPENDORF   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 12; INTERLEUKIN 13; INTERLEUKIN 33; INTERLEUKIN 4; INTERLEUKIN 5; TOXIN; TRANSCRIPTION FACTOR FOXP3; TRANSFORMING GROWTH FACTOR; TUMOR NECROSIS FACTOR ALPHA;

ACUTE LIVER FAILURE; ALCOHOL ABUSE; AUTOIMMUNE HEPATITIS; CD4+ T LYMPHOCYTE; CELL DEATH; EXPERIMENTAL MODEL; FIBROSIS; HEPATITIS; HUMAN; IMMUNE RESPONSE; IMMUNOCOMPETENT CELL; INFLAMMATION; ISCHEMIA; KUPFFER CELL; LIVER; LIVER CELL; LIVER CELL CARCINOMA; LIVER CIRRHOSIS; LIVER INJURY; MACROPHAGE; MORTALITY; NONALCOHOLIC FATTY LIVER; NONHUMAN; PATHOPHYSIOLOGY; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW; TH1 CELL; VIRUS INFECTION;

EID: 83555160887     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2011.05.007     Document Type: Editorial

References (25)

1. W. Bernal, G. Auzinger, A. Dhawan, and J. Wendon Acute liver failure Lancet 376 2010 190 201
2. I.N. Hines, and M.D. Wheeler Recent advances in alcoholic liver disease III. Role of the innate immune response in alcoholic hepatitis Am J Physiol Gastrointest Liver Physiol 287 2004 G310 G314
3. K. Shimamura, H. Kawamura, T. Nagura, T. Kato, T. Naito, and H. Kameyama Association of NKT cells and granulocytes with liver injury after reperfusion of the portal vein Cell Immunol 234 2005 31 38 (Pubitemid 41140389)
4. G. Tiegs, J. Hentschel, and A. Wendel A T-cell dependent experimental liver injury in mice inducible by concanavalin A J Clin Invest 90 1992 196 203
5. Q. Cao, R. Batey, G. Pang, A. Russell, and R. Clancy IL-6, IFN-gamma and TNF-alpha production by liver-associated T cells and acute liver injury in rats administered concanavalin A Immunol Cell Biol 76 1998 542 549 (Pubitemid 29003057)
6. A. Erhardt, and G. Tiegs Tolerance induction in response to liver inflammation Dig Dis 28 2010 86 92
7. S. Küsters, F. Gantner, G. Künstle, and G. Tiegs Interferon-γ plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A Gastroenterology 111 1996 462 471 (Pubitemid 26256736)
8. J. Schümann, D. Wolf, A. Pahl, K. Brune, T. Papadopoulos, and N. van Rooijen Importance of Kupffer cells for T cell-dependent liver injury in mice Am J Pathol 157 2000 1671 1683
9. F. Nicoletti, R. Di Marco, P. Zaccone, A. Salvaggio, G. Magro, and K. Bendtzen Murine concanavalin A-induced hepatitis is prevented by interleukin 12 (IL-12) antibody and exacerbated by exogenous IL-12 through an interferon-γ-dependent mechanism Hepatology 32 2000 728 733
10. R. Faggioni, J. Jones-Carson, D.A. Reed, C.A. Dinarello, K.R. Feingold, and C. Grunfeld Leptin-deficient (ob/ob) mice are protected from T cell-mediated hepatotoxicity: role of tumor necrosis factor alpha and IL-18 Proc Natl Acad Sci USA 97 2000 2367 2372 (Pubitemid 30134075)
11. H. Louis, O. Moine, M.O. Peny, E. Quertinmont, D. Fokan, and M. Goldman Production and role of interleukin-10 in concanavalin A-induced hepatitis in mice Hepatology 25 1997 1382 1389 (Pubitemid 27250758)
12. H. Louis, A. Le Moine, E. Quertinmont, M.O. Peny, A. Geerts, and M. Goldman Repeated concanavalin A challenge in mice induces an interleukin 10-producing phenotype and liver fibrosis Hepatology 31 2000 381 390 (Pubitemid 30078603)
13. K. Takeda, Y. Hayakawa, L. Van Kaer, H. Matsuda, H. Yagita, and K. Okumura Critical contribution of liver natural killer T cells to a murine model of hepatitis Proc Natl Acad Sci USA 97 2000 5498 5503 (Pubitemid 30313747)
14. Y. Kaneko, M. Harada, T. Kawano, M. Yamashita, Y. Shibata, and F. Gejyo Augmentation of Vα14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitis J Exp Med 191 2000 105 114 (Pubitemid 30043652)
15. J. Schmitz, A. Owyang, E. Oldham, Y. Song, E. Murphy, and T.K. McClanahan IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines Immunity 23 2005 479 490 (Pubitemid 41587888)
16. F.Y. Liew, N.I. Pitman, and I.B. McInnes Disease-associated functions of IL-33: the new kid in the IL-1 family Nat Rev Immunol 10 2010 103 110
17. A. Erhardt, M. Biburger, T. Papadopoulos, and G. Tiegs IL-10, regulatory T cells, and Kupffer cells mediate tolerance in concanavalin A-induced liver injury in mice Hepatology 45 2007 475 485 (Pubitemid 46374604)
18. A. Erhardt, C. Wegscheid, B. Claass, A. Carambia, J. Herkel, and H.W. Mittrucker CXCR3 deficiency exacerbates liver disease and abrogates tolerance in a mouse model of immune-mediated hepatitis J Immunol 186 2011 5284 5293
19. + regulatory T cells protect against T cell-mediated fulminant hepatitis in a TGF-beta-dependent manner in mice J Immunol 181 2008 7221 7229
20. G.A. Roth, M. Zimmermann, B.A. Lubsczyk, J. Pilz, P. Faybik, and H. Hetz Up-regulation of interleukin 33 and soluble ST2 serum levels in liver failure J Surg Res 163 2010 e79 e83
21. P. Marvie, M. Lisbonne, A. L'Helgoualc'h, M. Rauch, B. Turlin, and L. Preisser Interleukin-33 overexpression is associated with liver fibrosis in mice and humans J Cell Mol Med 14 2010 1726 1739
22. A. Amatucci, T. Novobrantseva, K. Gilbride, M. Brickelmaier, P. Hochman, and A. Ibraghimov Recombinant ST2 boosts hepatic Th2 response in vivo J Leukoc Biol 82 2007 124 132 (Pubitemid 47026424)
23. C. Moussion, N. Ortega, and J.P. Girard The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel 'alarmin'? PLoS One 3 2008 e3331
24. P.A. Knolle, G. Gerken, E. Loser, H.P. Dienes, F. Gantner, and G. Tiegs Role of sinusoidal endothelial cells of the liver in concanavalin A-induced hepatic injury in mice Hepatology 24 1996 824 829 (Pubitemid 26334281)
25. K. Oboki, T. Ohno, N. Kajiwara, K. Arae, H. Morita, and A. Ishii IL-33 is a crucial amplifier of innate rather than acquired immunity Proc Natl Acad Sci USA 107 2010 18581 18586