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Volumn 76, Issue 6, 1998, Pages 542-549

IL-6, IFN-γ and TNF-α production by liver-associated T cells and acute liver injury in rats administered concanavalin A

Author keywords

Concanavalin A; IFN ; IL 6; Liver associated lymphocytes; TNF

Indexed keywords

ALANINE AMINOTRANSFERASE; CD4 ANTIGEN; CD8 ANTIGEN; CONCANAVALIN A; GAMMA INTERFERON; INTERLEUKIN 2 RECEPTOR; INTERLEUKIN 6; TUMOR NECROSIS FACTOR ALPHA;

EID: 0032437014     PISSN: 08189641     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1440-1711.1998.00779.x     Document Type: Article
Times cited : (71)

References (21)
  • 1
    • 0028934983 scopus 로고
    • Molecular biological aspects of alcohol-induced liver disease
    • Arnon R, Esposti SD, Zern MA. Molecular biological aspects of alcohol-induced liver disease. Alcohol. Clin. Exp. Res. 1995; 19: 247-56.
    • (1995) Alcohol. Clin. Exp. Res. , vol.19 , pp. 247-256
    • Arnon, R.1    Esposti, S.D.2    Zern, M.A.3
  • 2
    • 0028795171 scopus 로고
    • Concanavalin A-induced T-cell-mediated hepatic injury in mice: The role of tumor necrosis factor
    • Gantner F, Leist M, Lohse AW, Germann PG, Tiegs G. Concanavalin A-induced T-cell-mediated hepatic injury in mice: The role of tumor necrosis factor. Hepatology 1995; 21: 190-6.
    • (1995) Hepatology , vol.21 , pp. 190-196
    • Gantner, F.1    Leist, M.2    Lohse, A.W.3    Germann, P.G.4    Tiegs, G.5
  • 4
    • 0026643743 scopus 로고
    • A T cell-dependent experimental liver injury in mice inducible by Concanavalin A
    • Tiegs G, Hentschel J, Wendel A. A T cell-dependent experimental liver injury in mice inducible by Concanavalin A. J. Clin. Invest. 1992; 90: 196-203.
    • (1992) J. Clin. Invest. , vol.90 , pp. 196-203
    • Tiegs, G.1    Hentschel, J.2    Wendel, A.3
  • 5
    • 0030983660 scopus 로고    scopus 로고
    • Ethanol feeding enhances inflammatory cytokine expression in lipopolysaccharide-induced hepatitis
    • Pennington HL, Hall P. Wilce PA, Worrall S. Ethanol feeding enhances inflammatory cytokine expression in lipopolysaccharide-induced hepatitis. J. Gastroenterol. Hepatol. 1997; 12: 305-13.
    • (1997) J. Gastroenterol. Hepatol. , vol.12 , pp. 305-313
    • Pennington, H.L.1    Hall, P.2    Wilce, P.A.3    Worrall, S.4
  • 6
    • 0029121402 scopus 로고
    • Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease
    • Kamimura S, Tsukamoto H. Cytokine gene expression by Kupffer cells in experimental alcoholic liver disease. Hepatology 1995; 21: 1304-9.
    • (1995) Hepatology , vol.21 , pp. 1304-1309
    • Kamimura, S.1    Tsukamoto, H.2
  • 7
    • 0029936091 scopus 로고    scopus 로고
    • Hepatic sinusoidal endothelial cell in alcoholemia and endotoxemia
    • Deaciuc IV, Spitzer JJ. Hepatic sinusoidal endothelial cell in alcoholemia and endotoxemia. Alcohol. Clin. Exp. Res. 1996; 20: 607-14.
    • (1996) Alcohol. Clin. Exp. Res. , vol.20 , pp. 607-614
    • Deaciuc, I.V.1    Spitzer, J.J.2
  • 9
    • 0025977602 scopus 로고
    • Kinetics of TNF, IL-6 and IL-8 gene expression in LPS-stimulated human whole blood
    • DeForge LE, Remick DG. Kinetics of TNF, IL-6 and IL-8 gene expression in LPS-stimulated human whole blood. Biochem. Biophys. Res. Commun. 1991; 174: 18-24.
    • (1991) Biochem. Biophys. Res. Commun. , vol.174 , pp. 18-24
    • DeForge, L.E.1    Remick, D.G.2
  • 10
    • 0031887544 scopus 로고    scopus 로고
    • Decreased tumour necrosis factor-α and interleukin-1α production from intrahepatic mononuclear cells in chronic ethanol consumption and upregulation by endotoxin
    • Batey R, Cao Q, Madsen G, Pang G, Russell A, Clancy R. Decreased tumour necrosis factor-α and interleukin-1α production from intrahepatic mononuclear cells in chronic ethanol consumption and upregulation by endotoxin. Alcohol. Clin. Exp. Res. 1998; 22: 150-6.
    • (1998) Alcohol. Clin. Exp. Res. , vol.22 , pp. 150-156
    • Batey, R.1    Cao, Q.2    Madsen, G.3    Pang, G.4    Russell, A.5    Clancy, R.6
  • 11
    • 0030017301 scopus 로고    scopus 로고
    • Interferon gamma plays a critical role in T-cell-dependent liver injury in mice initiated by Concanavalin A
    • Kusters S, Gnatner F, Kunstle G, Tiegs G. Interferon gamma plays a critical role in T-cell-dependent liver injury in mice initiated by Concanavalin A. Gastroenterology 1996; 111: 462-71.
    • (1996) Gastroenterology , vol.111 , pp. 462-471
    • Kusters, S.1    Gnatner, F.2    Kunstle, G.3    Tiegs, G.4
  • 12
    • 15844425587 scopus 로고    scopus 로고
    • Critical involvement of interferon gamma in the pathogenesis of T-cell activation-associated hepatitis and regulatory mechanisms of interleukin-6 for the manifestations of hepatitis
    • Mizuhara H, Uno M, Seki N et al. Critical involvement of interferon gamma in the pathogenesis of T-cell activation-associated hepatitis and regulatory mechanisms of interleukin-6 for the manifestations of hepatitis. Hepatology 1996; 23: 1608-15.
    • (1996) Hepatology , vol.23 , pp. 1608-1615
    • Mizuhara, H.1    Uno, M.2    Seki, N.3
  • 13
    • 0028300351 scopus 로고
    • T cell activation associated hepatic injury: Mediation by tumor necrosis factors and protection by Interleukin-6
    • Mizuhara H, O'Neill E, Seki N et al. T cell activation associated hepatic injury: Mediation by tumor necrosis factors and protection by Interleukin-6. J. Exp. Med. 1994; 179: 1529-37.
    • (1994) J. Exp. Med. , vol.179 , pp. 1529-1537
    • Mizuhara, H.1    O'Neill, E.2    Seki, N.3
  • 15
    • 0023739278 scopus 로고
    • Functional discrimination between interleukin-6 and interleukin 1
    • Helle M, Boeije L, Aarden LA. Functional discrimination between interleukin-6 and interleukin 1. Eur. J. Immunol. 1988; 18: 1535-40.
    • (1988) Eur. J. Immunol. , vol.18 , pp. 1535-1540
    • Helle, M.1    Boeije, L.2    Aarden, L.A.3
  • 17
    • 0027176368 scopus 로고
    • Functional characterization of liver-associated lymphocytes in patients with metis
    • Winnock M, Garcia Barcina M, Huet S et al. Functional characterization of liver-associated lymphocytes in patients with metis. Gastroenterology 1991; 105: 1152-8.
    • (1991) Gastroenterology , vol.105 , pp. 1152-1158
    • Winnock, M.1    Garcia Barcina, M.2    Huet, S.3
  • 18
    • 0026161883 scopus 로고
    • Liver sinusoidal cytotoxic cells are recruited from blood and divide locally
    • Lukomska B, Pienkowska B, Andrzejewski W, Olszewski WL. Liver sinusoidal cytotoxic cells are recruited from blood and divide locally. J. Hepatol. 1991; 12: 332-5.
    • (1991) J. Hepatol. , vol.12 , pp. 332-335
    • Lukomska, B.1    Pienkowska, B.2    Andrzejewski, W.3    Olszewski, W.L.4
  • 19
    • 0032522802 scopus 로고    scopus 로고
    • Disparate roles for TNF-α and Fas ligand in Concanavalin-A-induced hepatitis
    • Riade K, Colagiovanni DB, Joselphs MD et al. Disparate roles for TNF-α and Fas ligand in Concanavalin-A-induced hepatitis. J. Immunol. 1998; 160: 4082-9.
    • (1998) J. Immunol. , vol.160 , pp. 4082-4089
    • Riade, K.1    Colagiovanni, D.B.2    Joselphs, M.D.3
  • 20
    • 0031201023 scopus 로고    scopus 로고
    • Suppression of Concanavalin A-induced hepatitis in IFNγ mice, but not TNF-α mice. Role for IFN-γ in activating apoptosis of hepatocytes
    • Tagawa Y, Sekikawa K, Iwakura Y. Suppression of Concanavalin A-induced hepatitis in IFNγ mice, but not TNF-α mice. Role for IFN-γ in activating apoptosis of hepatocytes. J. Immunol. 1997; 159: 1418-28.
    • (1997) J. Immunol. , vol.159 , pp. 1418-1428
    • Tagawa, Y.1    Sekikawa, K.2    Iwakura, Y.3
  • 21
    • 0031572443 scopus 로고    scopus 로고
    • IL-18 accounts for both TNF-α and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice
    • Tsutsui H, Matsui K, Kawada N et al. IL-18 accounts for both TNF-α and Fas ligand-mediated hepatotoxic pathways in endotoxin-induced liver injury in mice. J. Immunol. 1997; 159: 3961-7.
    • (1997) J. Immunol. , vol.159 , pp. 3961-3967
    • Tsutsui, H.1    Matsui, K.2    Kawada, N.3


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