Gender association of the angiotensin-converting enzyme gene with ischaemic stroke

JRAAS - Journal of the Renin-Angiotensin-Aldosterone System

Volumn 12, Issue 4, 2011, Pages 510-515

  Markoula, Sofia ^a   Giannopoulos, Sotirios ^a   Kostoulas, Charilaos ^b   Tatsioni, Athina ^c   Bouba, Ioanna ^b   Maranis, Sotirios ^a   Georgiou, Ioannis ^b   Kyritsis, Athanassios P ^a  

^a UNIVERSITY OF IOANNINA   (Greece)

^b UNIVERSITY HOSPITAL OF IOANNINA   (Greece)

^c TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

ACE; gender dimorphism; genes; ID polymorphism; stroke

Indexed keywords

DIPEPTIDYL CARBOXYPEPTIDASE;

ARTERY OCCLUSION; ARTICLE; BRAIN ATHEROSCLEROSIS; BRAIN ISCHEMIA; CARDIOVASCULAR RISK; CLINICAL ASSESSMENT; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED STUDY; ELECTROCARDIOGRAM; FEMALE; GENE FREQUENCY; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENETIC SUSCEPTIBILITY; GENOTYPE; HOMOZYGOSITY; HUMAN; HYPERCHOLESTEROLEMIA; HYPERTENSION; INDEL MUTATION; MAJOR CLINICAL STUDY; MALE; POLYMERASE CHAIN REACTION; RENIN ANGIOTENSIN ALDOSTERONE SYSTEM; RISK ASSESSMENT; SEX DIFFERENCE; TRANSESOPHAGEAL ECHOCARDIOGRAPHY; TRANSTHORACIC ECHOCARDIOGRAPHY;

ATHEROSCLEROSIS; CASE-CONTROL STUDIES; FEMALE; GENE FREQUENCY; GENETIC PREDISPOSITION TO DISEASE; HUMANS; HYPERTENSION; MALE; MIDDLE AGED; MYOCARDIAL ISCHEMIA; PEPTIDYL-DIPEPTIDASE A; SEX CHARACTERISTICS; STROKE;

EID: 83455225623     PISSN: 14703203     EISSN: 17528976     Source Type: Journal    
DOI: 10.1177/1470320310391333     Document Type: Article

References (32)

1. Sharma P. Genes for ischemic stroke: strategies for their detection. J Hypertens. 1996 ; 14: 277-285 (Pubitemid 26137622)
2. Graffagnino C, Gasecki AP, Doig GS, Hachinski VC. The importance of family history in cerebrovascular disease. Stroke. 1994 ; 25: 1599-1604 (Pubitemid 24233965)
3. Jiang X, Sheng H, Li J, Xun P, Cheng Y, Huang J, et al. Association between renin-angiotensin system gene polymorphism and essential hypertension: a community-based study. J Hum Hypertens. 2009 ; 23: 176-181
4. Morishita R, Gibbons GH, Ellison KE, Lee W, Zhang L, Yu H, et al. Evidence for direct local angiotensin in vascular hypertrophy: in vivo gene transfer of angiotensin converting enzyme. J Clin Invest. 1994 ; 94: 978-984
5. Sharma P. Meta-analysis of the ACE gene in ischemic stroke. J Neurol Neurosurg Psychiatry. 1998 ; 64: 227-230 (Pubitemid 28159806)
6. Doi Y, Yoshinari M, Yoshizumi H, Ibayashi S, Wakisaka M, Fujishima M. Polymorphism of the angiotensin-converting enzyme (ACE) gene in patients with thrombotic brain infarction. Atherosclerosis. 1997 ; 132: 145-150 (Pubitemid 27311005)
7. Juo SH. Genetics of carotid atherosclerosis. Front Biosci. 2009 ; 14: 4525-4534
8. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin-1 converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest. 1990 ; 86: 1343-1346 (Pubitemid 20370444)
9. Paternoster L, Chen W, Sudlow CL. Genetic determinants of white matter hyperintensities on brain scans: a systematic assessment of 19 candidate gene polymorphisms in 46 studies in 19,000 subjects. Stroke. 2009 ; 40: 2020-2026
10. Zee RY, Ridker PM, Stampfer MJ, Hennekens CH, Lindpaintner K. Prospective evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of stroke. Circulation. 1999 ; 99: 340-343 (Pubitemid 29051257)
11. Takami S, Imai Y, Katsuya T, Ohkubo T, Tsuji I, Nagai K, et al. Gene polymorphisms of the renin-angiotensin system associates with risk for lacunar infarction-the Ohasama Study. Am J Hypertens. 2000 ; 13: 121-127 (Pubitemid 30125633)
12. Sayed-Tabatabaei FA, Houwing-Duistermaat JJ, van Duijn CM, Witteman JC. Angiotensin-converting enzyme gene polymorphisms and carotid artery wall thickness: a meta-analysis. Stroke. 2003 ; 34: 1634-1639 (Pubitemid 36842616)
13. Szolnoki Z, Melegh B. Gene-gene and gene-environment interplay represent specific susceptibility for different types of ischaemic stroke and leukoaraiosis. Curr Med Chem. 2006 ; 13: 1627-1634 (Pubitemid 43821696)
14. Adams HP, Bendixen BH, Kappelle LJ, Biller J, Love BB, Gordon DL, et al. Classification of subtype of acute ischemic stroke: definitions for use in a multicenter clinical trial. Stroke. 1993 ; 24: 35-41 (Pubitemid 23014379)
15. Rigat B, Hubert C, Alhenc-Gelas F, Cambien F, Corvol P, Soubrier F. An insertion/deletion polymorphism in the angiotensin I-converting enzyme gene accounting for half the variance of serum enzyme levels. J Clin Invest. 1990 ; 86: 1343-1346 (Pubitemid 20370444)
16. Karagiannis A, Balaska K, Tziomalos K, Tokalaki-Nikolaidou L, Papayeoryiou A, Zamboulis C. Lack of an association between angiotensin- converting enzyme gene insertion/deletion polymorphism and ischaemic stroke. Eur Neurol. 2004 ; 51: 148-152 (Pubitemid 38608314)
17. Zee RY, Ridker PM, Stampfer MJ, Hennekens CH, Lindpaintner K. Prospective evaluation of the angiotensin-converting enzyme insertion/deletion polymorphism and the risk of stroke. Circulation. 1999 ; 26 (99). 331-333
18. Ueda S, Weir CJ, Inglis GC, Murray GD, Muir KW, Lees KR. Lack of association between angiotensin converting enzyme gene insertion/deletion polymorphism and stroke. J Hypertension. 1995 ; 13: 1597-1601 (Pubitemid 26015782)
19. Agerholm-Larsen B, Nordestgaard BG, Tybjaerg-Hansen A. ACE gene polymorphism in cardiovascular disease: meta-analyses of small and large studies in whites. Arterioscler Thromb Vasc Biol. 2000 ; 20: 484-492 (Pubitemid 30086107)
20. Bielinski SJ, Lynch AI, Miller MB, Weder A, Cooper R, Oberman A, et al. Genome-wide linkage analysis for loci affecting pulse pressure: the Family Blood Pressure Program. Hypertension. 2005 ; 46: 1286-1293 (Pubitemid 43189725)
21. Lucarini L, Sticchi E, Sofi F, Pratesi G, Pratesi C, Pulli R, et al. ACE and TGFBR1 genes interact in influencing the susceptibility to abdominal aortic aneurysm. Atherosclerosis.. 2009 ; 202: 205-210
22. Reyes-Engel A, Morcillo L, Aranda FJ, Ruiz M, Gaitan MJ, Mayor-Olea A, et al. Influence of gender and genetic variability on plasma angiotensin peptides. J Renin Angiotensin Aldosterone Syst. 2006 ; 7: 92-97 (Pubitemid 44383503)
23. Lynch AI, Arnett DK, Davis BR, Boerwinkle E, Ford CE, Eckfeldt JH, et al. Sex-specific effects of AGT-6 and ACE I/D on pulse pressure after 6 months on antihypertensive treatment: the GenHAT study. Ann Hum Genet. 2007 ; 71: 735-745 (Pubitemid 47517257)
24. Danser AH, Derkx FH, Schalekamp MA, Hense HW, Riegger GA, Schunkert H. Determinants of interindividual variation of renin and prorenin concentrations: evidence for a sexual dimorphism of (pro)renin levels in humans. Hypertension. 1998 ; 16: 853-862 (Pubitemid 28247969)
25. Gallagher PE, Li P, Lenhart JR, Chappell MC, Brosnihan KB. Estrogen regulation of angiotensin-converting enzyme mRNA. Hypertension. 1999 ; 33: 323-328 (Pubitemid 29065679)
26. Tiret L, Rigat B, Visvikis S, Breda C, Corvol P, Cambien F, et al. Evidence, from combined segregation and linkage analysis, that a variant of the angiotensin I-converting enzyme (ACE) gene controls plasma ACE levels. Am J Hum Genet. 1992 ; 51: 197-205
27. Ay C, Bencur P, Vormittag R, Jungbauer C, Vukovich T, Mannhalter C, et al. The angiotensin-converting enzyme insertion/deletion polymorphism and serum levels of angiotensin-converting enzyme in venous thromboembolism. Data from a case control study. Thromb Haemost. 2007 ; 98: 777-782 (Pubitemid 47555069)
28. Bos MJ, Schuit SC, Koudstaal PJ, Hofman A, Uitterlinden AG, Breteler MM. Variation in the estrogen receptor alpha gene and risk of stroke: the Rotterdam Study. Stroke. 2008 ; 39: 1324-1326 (Pubitemid 351440709)
29. Lazaros L, Markoula S, Xita N, Giannopoulos S, Gogou P, Lagos G, et al. Association of estrogen receptor-alpha gene polymorphisms with stroke risk in patients with metabolic syndrome. Acta Neurol Scand. 2008 ; 117: 186-190 (Pubitemid 351190149)
30. González Ordóñez AJ, Fernández Carreira JM, Medina Rodríguez JM, Martín Sánchez L, Alvarez Díaz R, Alvarez Martinez MV, et al. Risk of venous thromboembolism associated with the insertion/deletion polymorphism in the angiotensin-converting enzyme gene. Blood Coagul Fibrinolysis. 2000 ; 11: 485-490 (Pubitemid 30618528)
31. Ruggenenti P, Perna A, Zoccali C, Gherardi G, Benini R, Testa A, et al. Chronic proteinuric nephropathies. II. Outcomes and response to treatment in a prospective cohort of 352 patients: differences between women and men in relation to the ACE gene polymorphism. Gruppo Italiano di Studi Epidemologici in Nefrologia (Gisen). J Am Soc Nephrol. 2000 ; 11: 88-96 (Pubitemid 30020430)
32. Hagberg JM, McCole SD, Brown MD, Ferrell RE, Wilund KR, Huberty A, et al. ACE insertion/deletion polymorphism and submaximal exercise hemodynamics in postmenopausal women. J Appl Physiol. 2002 ; 92: 1083-1088 (Pubitemid 34670964)