Double-Blind, Placebo-Controlled, Randomized Pilot Study of Cerebral Blood Flow Patterns Employing SPECT Imaging in Dental Postsurgical Pain Patients With and Without Pain Relief

Clinical Therapeutics

Volumn 33, Issue 12, 2011, Pages 1894-1903

  Newberg, Andrew B ^a   Hersh, Elliot V ^b   Levin, Lawrence M ^b   Giannakopoulos, Helen ^b   Secreto, Stacey A ^b   Wintering, Nancy A ^a   Farrar, John T ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b UNIVERSITY OF PENNSYLVANIA SCHOOL OF DENTAL MEDICINE   (United States)

Author keywords

Acute pain; Cerebral blood flow; Ibuprofen; Ketorolac; Placebo; SPECT

Indexed keywords

CYSTEINE ETHYL ESTER TC 99M; IBUPROFEN; KETOROLAC; PARACETAMOL; PLACEBO;

ADULT; ANALGESIA; ANTERIOR CINGULATE; ARTICLE; BRAIN ASYMMETRY; BRAIN BLOOD FLOW; CAUDATE NUCLEUS; CLINICAL ARTICLE; CONTROLLED STUDY; DOUBLE BLIND PROCEDURE; FEMALE; HUMAN; LEFT HEMISPHERE; LOCAL ANESTHESIA; MALE; MOLAR TOOTH; PAIN ASSESSMENT; PILOT STUDY; POSTOPERATIVE PAIN; PREFRONTAL CORTEX; RANDOMIZED CONTROLLED TRIAL; RATING SCALE; RIGHT HEMISPHERE; SENSORIMOTOR CORTEX; SINGLE PHOTON EMISSION COMPUTER TOMOGRAPHY; THALAMUS; TOOTH DISEASE; TOOTH EXTRACTION; TOOTH PAIN; TREATMENT OUTCOME; TREATMENT RESPONSE;

ACUTE PAIN; ADULT; ANALGESICS; BRAIN MAPPING; CEREBROVASCULAR CIRCULATION; CYSTEINE; DOUBLE-BLIND METHOD; FEMALE; HUMANS; MALE; MOLAR, THIRD; ORGANOTECHNETIUM COMPOUNDS; PAIN MEASUREMENT; PAIN PERCEPTION; PAIN, POSTOPERATIVE; PENNSYLVANIA; PILOT PROJECTS; PLACEBOS; RADIOPHARMACEUTICALS; TIME FACTORS; TOMOGRAPHY, EMISSION-COMPUTED, SINGLE-PHOTON; TOOTH EXTRACTION; TREATMENT OUTCOME; YOUNG ADULT;

EID: 83455220121     PISSN: 01492918     EISSN: 1879114X     Source Type: Journal    
DOI: 10.1016/j.clinthera.2011.10.013     Document Type: Article

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