Identification of selective class II histone deacetylase inhibitors using a novel dual-parameter binding assay based on fluorescence anisotropy and lifetime

Journal of Biomolecular Screening

Volumn 16, Issue 10, 2011, Pages 1206-1216

  Haus, Patricia ^a   Korbus, Michael ^a   Schröder, Michael ^a   Meyer Almes, Franz Josef ^a  

^a DARMSTADT UNIVERSITY OF APPLIED SCIENCES   (Germany)

Author keywords

binding assay; fluorescence lifetime; HDAC; HDAH; Histone deacetylase; inhibitor

Indexed keywords

HISTONE DEACETYLASE 2; HISTONE DEACETYLASE 6; ROMIDEPSIN; VORINOSTAT;

ANISOTROPY; ARTICLE; BINDING ASSAY; BORDETELLA; CONTROLLED STUDY; CUTANEOUS T CELL LYMPHOMA; DRUG IDENTIFICATION; DRUG SCREENING; ENZYME ASSAY; FLUORESCENCE; FLUORESCENCE LIFETIME; HIGH THROUGHPUT SCREENING; HUMAN; NONHUMAN; PARAMETERS OF MEASUREMENT AND ANALYSIS; PRIORITY JOURNAL; PROTEIN DOMAIN;

BINDING, COMPETITIVE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DISCOVERY; ENZYME ACTIVATION; FLUORESCENCE POLARIZATION; HISTONE DEACETYLASE INHIBITORS; HISTONE DEACETYLASES; HUMANS; PROTEIN BINDING; REPRODUCIBILITY OF RESULTS; SMALL MOLECULE LIBRARIES;

EID: 83455178133     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111424605     Document Type: Article

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