Development of a UHPLC method for the assessment of the metabolic profile of cinitapride

Journal of Separation Science

Volumn 34, Issue 24, 2011, Pages 3502-3508

  Marquez, Helena ^a   Albertí, Joan ^a   Salvà, Miquel ^a   Saurina, Javier ^b   Sentellas, Sonia ^a  

^a Department of Pharmacokinetics and Drug Metabolism ^*  (Spain)

^b UNIVERSITY OF BARCELONA   (Spain)

Author keywords

Cinitapride; Experimental design; Human liver microsomes; Metabolic profile; UHPLC

Indexed keywords

ANALYSIS TIME; CHROMATOGRAPHIC CONDITIONS; CHROMATOGRAPHIC METHODS; CINITAPRIDE; ELUTION GRADIENT; FIGURES OF MERITS; HUMAN LIVER MICROSOMES; IN-VITRO; LIMITS OF DETECTION; METABOLIC PROFILES; MOBILE PHASE; MULTI CRITERIA DECISION MAKING; RETENTION TIME; REVERSED PHASE; UHPLC;

ACETONITRILE; CHROMATOGRAPHIC ANALYSIS; CHROMATOGRAPHY; DESIGN OF EXPERIMENTS; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; METABOLITES; OPTIMIZATION; PHYSIOLOGY; STATISTICS;

METABOLISM;

ACETONITRILE; CINITAPRIDE; DRUG METABOLITE;

ACCURACY; AQUEOUS SOLUTION; ARTICLE; CONCENTRATION (PARAMETERS); DECISION MAKING; DRUG METABOLISM; EXPERIMENTAL DESIGN; HUMAN; HUMAN CELL; IN VITRO STUDY; LIMIT OF DETECTION; LIVER MICROSOME; PH; PRIORITY JOURNAL; ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;

BENZAMIDES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; HUMANS; MICROSOMES, LIVER;

EID: 83455176064     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201100073     Document Type: Article

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