A low blood volume LC-MS/MS assay for the quantification of fentanyl and its major metabolites norfentanyl and despropionyl fentanyl in children

Journal of Separation Science

Volumn 34, Issue 24, 2011, Pages 3568-3577

  Clavijo, Claudia F ^a   Thomas, James Joseph ^a   Cromie, Meghan ^a   Schniedewind, Björn ^a   Hoffman, Keith L ^a   Christians, Uwe ^a   Galinkin, Jeffrey L ^a,b  

^a UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^b CHILDREN S HOSPITAL COLORADO   (United States)

Author keywords

Despropionyl fentanyl; Dried blood spots; Fentanyl; Human plasma; Norfentanyl

Indexed keywords

ACCEPTANCE CRITERIA; ACCURACY AND PRECISION; BLOOD CONCENTRATIONS; BLOOD SAMPLES; BLOOD VOLUMES; DRIED BLOOD SPOTS; FENTANYLS; FILTER PAPERS; HUMAN PLASMAS; LC-MS/MS; LOWER LIMITS; MATRIX; MINIMALLY INVASIVE; MULTIPLE REACTION MONITORING; NORFENTANYL; PHARMACOKINETIC STUDIES; SIMULTANEOUS ANALYSIS; SURGICAL PROCEDURES; WHOLE BLOOD;

BIOMOLECULES; BLOOD; HEMODYNAMICS; METABOLISM; METABOLITES; PHARMACOKINETICS; PLASMAS;

ANESTHETICS;

DESPROPIONYL FENTANYL; DRUG METABOLITE; FENTANYL; NORFENTANYL; UNCLASSIFIED DRUG;

ARTICLE; BLOOD SAMPLING; BLOOD VOLUME; CHILD; DRUG BLOOD LEVEL; DRUG STRUCTURE; HUMAN; HUMAN TISSUE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; PRIORITY JOURNAL; TANDEM MASS SPECTROMETRY;

BLOOD VOLUME; CHILD; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FENTANYL; HUMANS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY;

EID: 83455176022     PISSN: 16159306     EISSN: 16159314     Source Type: Journal    
DOI: 10.1002/jssc.201100422     Document Type: Article

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