Endometrial and subendometrial perfusion are impaired in women with unexplained subfertility

Human Reproduction

Volumn 19, Issue 11, 2004, Pages 2605-2614

  Raine Fenning, Nick J ^a   Campbell, B K ^b   Kendall, N R ^b   Clewes, J S ^b   Johnson, I R ^b  

^a QUEEN S MEDICAL CENTRE   (United Kingdom)

^b UNIVERSITY OF NOTTINGHAM   (United Kingdom)

Author keywords

Endometrial perfussion; Menstrual cycle; Power Doppler; Three dimentional ultrasound; Unexplained subfertility

Indexed keywords

ESTRADIOL; PROGESTERONE;

ADULT; ANGIOGRAPHY; ARTICLE; CLINICAL ARTICLE; COMPUTER ANALYSIS; CONTROLLED STUDY; ENDOMETRIUM; ESTRADIOL BLOOD LEVEL; FEMALE; FEMALE INFERTILITY; FOLLICULAR PHASE; HUMAN; IMAGE ANALYSIS; LUTEAL PHASE; MENSTRUAL CYCLE; MENSTRUATION; MORPHOMETRICS; ORGANOGENESIS; OVULATION; PROGESTERONE BLOOD LEVEL; SIGNAL DETECTION; SUBFERTILITY; THREE DIMENSIONAL IMAGING; TISSUE PERFUSION; VASCULARIZATION;

EID: 8344274283     PISSN: 02681161     EISSN: None     Source Type: Journal    
DOI: 10.1093/humrep/deh459     Document Type: Article

References (56)

1. Achiron R, Levran D, Sivan E, Lipitz S, Dor J and Mashiach S (1995) Endometrial blood flow response to hormone replacement therapy in women with premature ovarian failure: a transvaginal Doppler study. Fertil Steril 63,550-554.
2. Amso NN, Watermeyer SR, Pugh N, O'Brien S and D'Angelo A (2001) Quantification of power Doppler energy, its future potential. Fertil Steril 76,583-587.
3. Applebaum M (1995) The uterine biophysical profile. Ultrasound Obstet Gynecol 5,67-68.
4. Azrin M (2001) Angiogenesis, protein and gene delivery. Br Med Bull 59,211-225.
5. Battaglia C, Larocca E, Lanzani A, Valentini M and Genazzani AR (1990) Doppler ultrasound studies of the uterine arteries in spontaneous and IVF stimulated ovarian cycles. Gynecol Endocrinol 4,245-250.
6. Bourne TH, Hagstrom HG, Granberg S, Josefsson B, Hahlin M, Hellberg P, Hamberger L and Collins WP (1996) Ultrasound studies of vascular and morphological changes in the human uterus after a positive self-test for the urinary luteinizing hormone surge. Hum Reprod 11,369-375.
7. Campbell S, Bourne TH, Tan SL and Collins WP (1994) Hysterosalpingo contrast sonography (HyCoSy) and its future role within the investigation of infertility in Europe. Ultrasound Obstet Gynecol 4,245-253.
8. Collins W, Jurkovic D, Bourne T, Kurjak A and Campbell S (1991) Ovarian morphology, endocrine function and intra-follicular blood flow during the peri-ovulatory period. Hum Reprod 6,319-324.
9. Coulam CB, Bustillo M, Soenksen DM and Britten S (1994) Ultrasonographic predictors of implantation after assisted reproduction. Fertil Steril 62,1004-1010.
10. de Ziegler D, Bulletti C, Fanchin R, Epiney M and Brioschi PA (2001) Contractility of the nonpregnant uterus: the follicular phase. Ann NY Acad Sci 943,172-184.
11. Donnelly EF, Geng L, Wojcicki WE, Fleischer AC and Hallahan DE (2001) Quantified power Doppler US of tumor blood flow correlates with microscopic quantification of tumor blood vessels. Radiology 219,166-170.
12. Ferenczy A, Bertrand G and Gelfand MM (1979) Proliferation kinetics of human endometrium during the normal menstrual cycle. Am J Obstet Gynecol 133,859-867.
13. Fleischer AC (1991) Ultrasound imaging - 2000: assessment of utero-ovarian blood flow with transvaginal color Doppler sonography; potential clinical applications in infertility. Fertil Steril 55,684-691.
14. Fleischer AC (2001) New developments in the sonographic assessment of ovarian, uterine and breast vascularity. Semin Ultrasound CT MR 22, 42-49.
15. discussion 1831-1833 Fortunato SJ (1996) The use of power Doppler and color power angiography in fetal imaging. Am J Obstet Gynecol 174, 1828-1831.
16. Friedler S, Schenker JG, Herman A and Lewin A (1996) The role of ultrasonography in the evaluation of endometrial receptivity following assisted reproductive treatments: a critical review. Hum Reprod Update 2, 323-335.
17. Gargett CE and Rogers PA (2001) Human endometrial angiogenesis. Reproduction 121,181-186.
18. Goswamy RK and Steptoe PC (1988) Doppler ultrasound studies of the uterine artery in spontaneous ovarian cycles. Hum Reprod 3,721-726.
19. Goswamy RK, Williams G and Steptoe PC (1988) Decreased uterine perfusion-a cause of infertility. Hum Reprod 3,955-959.
20. Graham CH, Fitzpatrick TE and McCrae KR (1998) Hypoxia stimulates urokinase receptor expression through a heme protein-dependent pathway. Blood 91,3300-3307.
21. Graham CH, Postovit LM, Park H, Canning MT and Fitzpatrick TE (2000) Adriana and Luisa Castellucci award lecture 1999: role of oxygen in the regulation of trophoblast gene expression and invasion. Placenta 21, 443-450.
22. Hsieh YY, Chang FC and Tsai HD (2000) Doppler evaluation of the uterine and spiral arteries from different sampling sites and phases of the menstrual cycle during controlled ovarian hyperstimulation. Ultrasound Obstet Gynecol 16,192-196.
23. Hull MG, Glazener CM, Kelly NJ, Conway DI, Foster PA, Hinton RA, Coulson C, Lambert PA, Watt EM and Desai KM (1985) Population study of causes, treatment and outcome of infertility. Br Med J (Clin Res Ed) 291,1693-1697.
24. Jarvela IY, Sladkevicius P, Tekay AH, Campbell S and Nargund G (2003) Intraobserver and interobserver variability of ovarian volume, gray-scale and color flow indices obtained using transvaginal three-dimensional power Doppler ultrasonography. Ultrasound Obstet Gynecol 21,277-282.
25. Jun WS, Lee KH, Koo K, Kim D, Kim JH, Kim SH, Choi BI and Han JK (2002) A straightforward algorithm for the quantification of power Doppler signals. Invest Radiol 37,343-348.
26. Kupesic S and Kurjak A (1993) Uterine and ovarian perfusion during the periovulatory period assessed by transvaginal color Doppler. Fertil Steril 60,439-443.
27. Kurjak A, Kupesic-Urek S, Schulman H and Zalud I (1991) Transvaginal color flow Doppler in the assessment of ovarian and uterine blood flow in infertile women. Fertil Steril 56,870-873.
28. Lessey BA (2000) The role of the endometrium during embryo implantation. Hum Reprod 15 (Suppl 6),39-50.
29. Levi-Setti PE, Rognoni G, Bozzo M, Ragusa G, Sulpizio P, Ferrazzi E and Pardi G (1995) Color-Doppler velocimetry of uterine arteries in pregnant and nonpregnant patients during multiovulation induction for IVF. J Assist Reprod Genet 12,413-417.
30. Lyons EA, Taylor PJ, Zheng XH, Ballard G, Levi CS and Kredentser JV (1991) Characterization of subendometrial myometrial contractions throughout the menstrual cycle in normal fertile women. Fertil Steril 55,771-774.
31. Meyerowitz CB, Fleischer AC, Pickens DR, Thurman GB, Borowsky AD, Thirsk G and Hellerqvist CG (1996) Quantification of tumor vascularity and flow with amplitude color Doppler sonography in an experimental model: preliminary results. J Ultrasound Med 15,827-833.
32. Pairleitner H, Steiner H, Hasenoehrl G and Staudach A (1999) Three-dimensional power Doppler sonography: imaging and quantifying blood flow and vascularization. Ultrasound Obstet Gynecol 14,139-143.
33. Peek M, Landgren BM and Johannisson E (1992) The endometrial capillaries during the normal menstrual cycle: a morphometric study. Hum Reprod 7,906-911.
34. Raine-Fenning NJ, Campbell BK, Clewes JS, Kendall NR and Johnson IR (2003) The reliability of virtual organ computer-aided analysis (VOCAL) for the semiquantification of ovarian, endometrial and subendometrial perfusion. Ultrasound Obstet Gynecol 22,633-639.
35. Raine-Fenning NJ, Campbell BK, Kendall NR, Clewes JS and Johnson IR (2004a) Quantifying the changes in endometrial vascularity throughout the normal menstrual cycle with three-dimensional power Doppler angiography. Hum Reprod 19,330-338.
36. Raine-Fenning NJ, Campbell BK, Clewes JS, Kendall NR and Johnson IR (2004b) The interobserver reliability of three-dimensional power Doppler data aquisition with the female pelvis. Ultrasound obstet Gynecol 23, 501-508.
37. Rubin JM and Adler RS (1993) Power Doppler expands standard color capability. Diagn Imaging (San Franc) 15,66-69.
38. Rubin JM, Bude RO, Carson PL, Bree RL and Adler RS (1994) Power Doppler US: a potentially useful alternative to mean frequency- based color Doppler US. Radiology 190,853-856.
39. Rubinstein M, Marazzi A and Polak de Fried E (1999) Low-dose aspirin treatment improves ovarian responsiveness, uterine and ovarian blood flow velocity, implantation and pregnancy rates in patients undergoing in vitro fertilization: a prospective, randomized, double-blind placebo-controlled assay. Fertil Steril 71,825-829.
40. Santolaya-Forgas J (1992) Physiology of the menstrual cycle by ultrasonography. J Ultrasound Med 11,139-142.
41. Scholtes MC, Wladimiroff JW, van Rijen HJ and Hop WC (1989) Uterine and ovarian flow velocity waveforms in the normal menstrual cycle: a transvaginal Doppler study. Fertil Steril 52,981-985.
42. Schwartz LB, Chiu AS, Courtney M, Krey L and Schmidt-Sarosi C (1997) The embryo versus endometrium controversy revisited as it relates to predicting pregnancy outcome in in-vitro fertilization-embryo transfer cycles. Hum Reprod 12,45-50.
43. Sharkey AM, Day K, McPherson A, Malik S, Licence D, Smith SK and Charnock-Jones DS (2000) Vascular endothelial growth factor expression in human endometrium is regulated by hypoxia. J Clin Endocrinol Metab 85,402-409.
44. Sher G and Fisch JD (2000) Vaginal sildenafil (Viagra): a preliminary report of a novel method to improve uterine artery blood flow and endometrial development in patients undergoing IVF. Hum Reprod 15,806-809.
45. Sher G and Fisch JD (2002) Effect of vaginal sildenafil on the outcome of in vitro fertilization (IVF) after multiple IVF failures attributed to poor endometrial development. Fertil Steril 78,1073-1076.
46. Sladkevicius P, Valentin L and Marsal K (1993) Blood flow velocity in the uterine and ovarian arteries during the normal menstrual cycle. Ultrasound Obstet Gynecol 3,199-208.
47. Steer CV, Campbell S, Pampiglione JS, Kingsland CR, Mason BA and Collins WP (1990) Transvaginal colour flow imaging of the uterine arteries during the ovarian and menstrual cycles. Hum Reprod 5,391-395.
48. Steer CV, Campbell S, Tan SL, Crayford T, Mills C, Mason BA and Collins WP (1992) The use of transvaginal color flow imaging after in vitro fertilization to identify optimum uterine conditions before embryo transfer. Fertil Steril 57,372-376.
49. Sterzik K, Grab D, Sasse V, Hutter W, Rosenbusch B and Terinde R (1989) Doppler sonographic findings and their correlation with implantation in an in vitro fertilization program. Fertil Steril 52,825-828.
50. Tan SL, Zaidi J, Campbell S, Doyle P and Collins W (1996) Blood flow changes in the ovarian and uterine arteries during the normal menstrual cycle. Am J Obstet Gynecol 175,625-631.
51. Tinkanen H, Kujansuu E and Laippala P (1994) Vascular resistance in uterine and ovarian arteries: its association with infertility and the prognosis of infertility. Eur J Obstet Gynecol Reprod Biol 57,111-115.
52. Turnbull LW, Lesny P and Killick SR (1995) Assessment of uterine receptivity prior to embryo transfer: a review of currently available imaging modalities. Hum Reprod Update 1,505-514.
53. World Health Organization (1999) WHO Laboratory Manual for the Examination of Human Semen and Sperm-Cervical Mucus Interaction. Cambridge Press, New York.
54. Yaron Y, Botchan A, Amit A, Peyser MR, David MP and Lessing JB (1994) Endometrial receptivity in the light of modern assisted reproductive technologies. Fertil Steril 62,225-232.
55. Zaidi J (2000) Blood flow changes in the ovarian and uterine arteries in women with normal and polycystic ovaries. Hum Fertil 3,194-198.
56. Zaidi J, Campbell S, Pittrof R and Tan SL (1995) Endometrial thickness, morphology, vascular penetration and velocimetry in predicting implantation in an in vitro fertilization program. Ultrasound Obstet Gynecol 6, 191-198.