메뉴 건너뛰기




Volumn 43, Issue 44, 2004, Pages 14064-14071

Characterization of the heptad repeat regions, HR1 and HR2, and design of a fusion core structure model of the spike protein from Severe Acute Respiratory Syndrome (SARS) coronavirus

Author keywords

[No Author keywords available]

Indexed keywords

BIOCHEMISTRY; ESCHERICHIA COLI; IMMUNOLOGY; PULMONARY DISEASES; VIRUSES;

EID: 8344260757     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi049101q     Document Type: Article
Times cited : (53)

References (32)
  • 3
    • 0021021580 scopus 로고
    • Coronavirus IBV: Structural characterization of the spike protein
    • Cavanagh, D. (1983) Coronavirus IBV: structural characterization of the spike protein, J. Gen. Virol. 64 (Part 12), 2577-2583.
    • (1983) J. Gen. Virol. , vol.64 , Issue.12 PART , pp. 2577-2583
    • Cavanagh, D.1
  • 4
    • 0020744820 scopus 로고
    • The biology of coronaviruses
    • Siddell, S., Wege, H., and Ter Meulen, V. (1983) The biology of coronaviruses, J. Gen. Virol. 64 (Part 4), 761-776.
    • (1983) J. Gen. Virol. , vol.64 , Issue.4 PART , pp. 761-776
    • Siddell, S.1    Wege, H.2    Ter Meulen, V.3
  • 5
    • 0032577550 scopus 로고    scopus 로고
    • HIV entry and its inhibition
    • Chan, D. C., and Kim, P. S. (1998) HIV entry and its inhibition, Cell 93, 681-684.
    • (1998) Cell , vol.93 , pp. 681-684
    • Chan, D.C.1    Kim, P.S.2
  • 6
    • 0034924823 scopus 로고    scopus 로고
    • Mechanisms of viral membrane fusion and its inhibition
    • Eckert, D. M., and Kim, P. S. (2001) Mechanisms of viral membrane fusion and its inhibition, Annu. Rev. Biochem. 70, 777-810.
    • (2001) Annu. Rev. Biochem. , vol.70 , pp. 777-810
    • Eckert, D.M.1    Kim, P.S.2
  • 7
    • 0035815282 scopus 로고    scopus 로고
    • The Fusion glycoprotein shell of Semliki Forest virus: An icosahedral assembly primed for fusogenic activation at endosomal pH
    • Lescar, J., Roussel, A., Wien, M. W., Navaza, J., Fuller, S. D., Wengler, G., and Rey, F. A. (2001) The Fusion glycoprotein shell of Semliki Forest virus: an icosahedral assembly primed for fusogenic activation at endosomal pH, Cell 105, 137-148.
    • (2001) Cell , vol.105 , pp. 137-148
    • Lescar, J.1    Roussel, A.2    Wien, M.W.3    Navaza, J.4    Fuller, S.D.5    Wengler, G.6    Rey, F.A.7
  • 8
    • 0030970693 scopus 로고    scopus 로고
    • Core structure of gp41 from the HIV envelope glycoprotein
    • Chan, D. C., Fass, D., Berger, J. M., and Kim, P. S. (1997) Core structure of gp41 from the HIV envelope glycoprotein, Cell 89, 263-273.
    • (1997) Cell , vol.89 , pp. 263-273
    • Chan, D.C.1    Fass, D.2    Berger, J.M.3    Kim, P.S.4
  • 9
    • 0035949493 scopus 로고    scopus 로고
    • Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region
    • Eckert, D. M., and Kim, P. S. (2001) Design of potent inhibitors of HIV-1 entry from the gp41 N-peptide region, Proc. Natl. Acad. Sci. U.S.A. 98, 11187-11192.
    • (2001) Proc. Natl. Acad. Sci. U.S.A. , vol.98 , pp. 11187-11192
    • Eckert, D.M.1    Kim, P.S.2
  • 10
    • 0035793406 scopus 로고    scopus 로고
    • Protein design of an HIV-1 entry inhibitor
    • Root, M. J., Kay, M. S., and Kim, P. S. (2001) Protein design of an HIV-1 entry inhibitor, Science 291, 884-888.
    • (2001) Science , vol.291 , pp. 884-888
    • Root, M.J.1    Kay, M.S.2    Kim, P.S.3
  • 11
    • 0028023726 scopus 로고
    • Structure of influenza haemagglutinin at the pH of membrane fusion
    • Bullough, P. A., Hughson, F. M., Skehel, J. J., and Wiley, D. C. (1994) Structure of influenza haemagglutinin at the pH of membrane fusion, Nature 371, 37-43.
    • (1994) Nature , vol.371 , pp. 37-43
    • Bullough, P.A.1    Hughson, F.M.2    Skehel, J.J.3    Wiley, D.C.4
  • 12
    • 0032214714 scopus 로고    scopus 로고
    • Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain
    • Weissenhorn, W., Carfi, A., Lee, K. H., Skehel, J. J., and Wiley, D. C. (1998) Crystal structure of the Ebola virus membrane fusion subunit, GP2, from the envelope glycoprotein ectodomain, Mol. Cell 2, 605-616.
    • (1998) Mol. Cell , vol.2 , pp. 605-616
    • Weissenhorn, W.1    Carfi, A.2    Lee, K.H.3    Skehel, J.J.4    Wiley, D.C.5
  • 14
    • 0034687711 scopus 로고    scopus 로고
    • Structural characterization of the human respiratory syncytial virus fusion protein core
    • Zhao, X., Singh, M., Malashkevich, V. N., and Kim, P. S. (2000) Structural characterization of the human respiratory syncytial virus fusion protein core, Proc. Natl. Acad. Sci. U.S.A. 97, 14172-14177.
    • (2000) Proc. Natl. Acad. Sci. U.S.A. , vol.97 , pp. 14172-14177
    • Zhao, X.1    Singh, M.2    Malashkevich, V.N.3    Kim, P.S.4
  • 16
    • 0042208243 scopus 로고    scopus 로고
    • The coronavirus spike protein is a class I virus fusion protein: Structural and functional characterization of the fusion core complex
    • Bosch, B. J., van der Zee, R., de Haan, C. A., and Rottier, P. J. (2003) The coronavirus spike protein is a class I virus fusion protein: structural and functional characterization of the fusion core complex, J. Virol. 77, 8801-8811.
    • (2003) J. Virol. , vol.77 , pp. 8801-8811
    • Bosch, B.J.1    Van Der Zee, R.2    De Haan, C.A.3    Rottier, P.J.4
  • 17
    • 0033214895 scopus 로고    scopus 로고
    • Inhibiting HIV-1 entry: Discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket
    • Eckert, D. M., Malashkevich, V. N., Hong, L. H., Carr, P. A., and Kim, P. S. (1999) Inhibiting HIV-1 entry: discovery of D-peptide inhibitors that target the gp41 coiled-coil pocket, Cell 99, 103-115.
    • (1999) Cell , vol.99 , pp. 103-115
    • Eckert, D.M.1    Malashkevich, V.N.2    Hong, L.H.3    Carr, P.A.4    Kim, P.S.5
  • 18
    • 0027959493 scopus 로고
    • Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection
    • Wild, C. T., Shugars, D. C., Greenwell, T. K., McDanal, C. B., and Matthews, T. J. (1994) Peptides corresponding to a predictive alpha-helical domain of human immunodeficiency virus type 1 gp41 are potent inhibitors of virus infection, Proc. Natl. Acad. Sci. U.S.A. 91, 9770-9774.
    • (1994) Proc. Natl. Acad. Sci. U.S.A. , vol.91 , pp. 9770-9774
    • Wild, C.T.1    Shugars, D.C.2    Greenwell, T.K.3    McDanal, C.B.4    Matthews, T.J.5
  • 20
    • 0033618320 scopus 로고    scopus 로고
    • LearnCoil-VMF: Computational evidence for coiled-coil-like motifs in many viral membrane-fusion proteins
    • Singh, M., Berger, B., and Kim, P. S. (1999) LearnCoil-VMF: computational evidence for coiled-coil-like motifs in many viral membrane-fusion proteins, J. Mol. Biol. 290, 1031-1041.
    • (1999) J. Mol. Biol. , vol.290 , pp. 1031-1041
    • Singh, M.1    Berger, B.2    Kim, P.S.3
  • 21
    • 2442705099 scopus 로고    scopus 로고
    • Following the rule: Formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors
    • Zhu, J., Xiao, G., Xu, Y., Yuan, F., Zheng, C., Liu, Y., Yan, H., Cole, D. K., Bell, J. I., Rao, Z., Tien, P. and Gao, G. F. (2004) Following the rule: formation of the 6-helix bundle of the fusion core from severe acute respiratory syndrome coronavirus spike protein and identification of potent peptide inhibitors, Biochem. Biophys. Res. Commun. 319, 283-288.
    • (2004) Biochem. Biophys. Res. Commun. , vol.319 , pp. 283-288
    • Zhu, J.1    Xiao, G.2    Xu, Y.3    Yuan, F.4    Zheng, C.5    Liu, Y.6    Yan, H.7    Cole, D.K.8    Bell, J.I.9    Rao, Z.10    Tien, P.11    Gao, G.F.12
  • 22
    • 0038268418 scopus 로고    scopus 로고
    • Biochemical and biophysical analysis of heptad repeat regions from the fusion protein of Menangle virus, a newly emergent paramyxovirus
    • Zhu, J. Q., Zhang, C. W., Rao, Z., Tien, P., and Gao, G. F. (2003) Biochemical and biophysical analysis of heptad repeat regions from the fusion protein of Menangle virus, a newly emergent paramyxovirus, Arch. Virol. 148, 1301-1316.
    • (2003) Arch. Virol. , vol.148 , pp. 1301-1316
    • Zhu, J.Q.1    Zhang, C.W.2    Rao, Z.3    Tien, P.4    Gao, G.F.5
  • 23
    • 1242340426 scopus 로고    scopus 로고
    • Basis for fusion inhibition by peptides: Analysis of the heptad repeat regions of the fusion proteins from Nipah and Hendra viruses, newly emergent zoonotic paramyxoviruses
    • Xu, Y., Gao, S., Cole, D. K., Zhu, J., Su, N., Wang, H., Gao, G. F., and Rao, Z. (2004) Basis for fusion inhibition by peptides: analysis of the heptad repeat regions of the fusion proteins from Nipah and Hendra viruses, newly emergent zoonotic paramyxoviruses, Biochem. Biophys. Res. Commun. 315, 664-670.
    • (2004) Biochem. Biophys. Res. Commun. , vol.315 , pp. 664-670
    • Xu, Y.1    Gao, S.2    Cole, D.K.3    Zhu, J.4    Su, N.5    Wang, H.6    Gao, G.F.7    Rao, Z.8
  • 24
    • 0036926562 scopus 로고    scopus 로고
    • The fusion protein core of measles virus forms stable coiled-coil trimer
    • Zhu, J., Zhang, C. W., Qi, Y., Tien, P., and Gao, G. F. (2002) The fusion protein core of measles virus forms stable coiled-coil trimer, Biochem. Biophys. Res. Commun. 299, 897-902.
    • (2002) Biochem. Biophys. Res. Commun. , vol.299 , pp. 897-902
    • Zhu, J.1    Zhang, C.W.2    Qi, Y.3    Tien, P.4    Gao, G.F.5
  • 25
    • 0032431055 scopus 로고    scopus 로고
    • Coiled coils in both intracellular vesicle and viral membrane fusion
    • Skehel, J. J., and Wiley, D. C. (1998) Coiled coils in both intracellular vesicle and viral membrane fusion, Cell 95, 871-874.
    • (1998) Cell , vol.95 , pp. 871-874
    • Skehel, J.J.1    Wiley, D.C.2
  • 26
    • 0032935886 scopus 로고    scopus 로고
    • The paramyxovirus fusion protein forms an extremely stable core trimer: Structural parallels to influenza virus haemagglutinin and HIV-1 gp41
    • Lamb, R. A., Joshi, S. B., and Dutch, R. E. (1999) The paramyxovirus fusion protein forms an extremely stable core trimer: structural parallels to influenza virus haemagglutinin and HIV-1 gp41, Mol. Membr. Biol. 16, 11-19.
    • (1999) Mol. Membr. Biol. , vol.16 , pp. 11-19
    • Lamb, R.A.1    Joshi, S.B.2    Dutch, R.E.3
  • 28
    • 0034120341 scopus 로고    scopus 로고
    • Membrane fusion mediated by coiled coils: A hypothesis
    • Bentz, J. (2000) Membrane fusion mediated by coiled coils: a hypothesis, Biophys. J. 78, 886-900.
    • (2000) Biophys. J. , vol.78 , pp. 886-900
    • Bentz, J.1
  • 29
    • 0033783032 scopus 로고    scopus 로고
    • Receptor binding and membrane fusion in virus entry: The influenza hemagglutinin
    • Skehel, J. J., and Wiley, D. C. (2000) Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin, Annu. Rev. Biochem. 69, 531-569.
    • (2000) Annu. Rev. Biochem. , vol.69 , pp. 531-569
    • Skehel, J.J.1    Wiley, D.C.2
  • 30
    • 12144287276 scopus 로고    scopus 로고
    • Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: Implications for virus fusogenic mechanism and identification of fusion inhibitors
    • Liu, S., Xiao, G., Chen, Y., He, Y., Niu, J., Escalante, C. R., Xiong, H., Farmar, J., Debnath, A. K., Tien, P., and Jiang, S. (2004) Interaction between heptad repeat 1 and 2 regions in spike protein of SARS-associated coronavirus: implications for virus fusogenic mechanism and identification of fusion inhibitors, Lancet 363, 938-947.
    • (2004) Lancet , vol.363 , pp. 938-947
    • Liu, S.1    Xiao, G.2    Chen, Y.3    He, Y.4    Niu, J.5    Escalante, C.R.6    Xiong, H.7    Farmar, J.8    Debnath, A.K.9    Tien, P.10    Jiang, S.11
  • 31
    • 3142663245 scopus 로고    scopus 로고
    • Structural basis for coronavirus-mediated membrane fusion: Crystal structure of MHV spike protein fusion core
    • Xu, Y., Liu, Y., Lou, Z., Qin, L., Li, X., Bai, Z., Pang, H., Tien, P., Gao, G. F., and Rao, Z. (2004) Structural basis for coronavirus-mediated membrane fusion: Crystal structure of MHV spike protein fusion core, J. Biol. Chem., M403760200.
    • (2004) J. Biol. Chem.
    • Xu, Y.1    Liu, Y.2    Lou, Z.3    Qin, L.4    Li, X.5    Bai, Z.6    Pang, H.7    Tien, P.8    Gao, G.F.9    Rao, Z.10
  • 32
    • 0033106334 scopus 로고    scopus 로고
    • Structural basis for paramyxovirus-mediated membrane fusion
    • Baker, K. A., Dutch, R. E., Lamb, R. A., and Jardetzky, T. S. (1999) Structural basis for paramyxovirus-mediated membrane fusion, Mol. Cell 3, 309-319.
    • (1999) Mol. Cell , vol.3 , pp. 309-319
    • Baker, K.A.1    Dutch, R.E.2    Lamb, R.A.3    Jardetzky, T.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.