PH-responsive interpenetrating network hydrogel beads of poly(acrylamide)-g-carrageenan and sodium alginate for intestinal targeted drug delivery: Synthesis, in vitro and in vivo evaluation

Journal of Colloid and Interface Science

Volumn 367, Issue 1, 2012, Pages 509-517

  Kulkarni, Raghavendra V ^a   Boppana, Rashmi ^a,d   Krishna Mohan, G ^b   Mutalik, Srinivas ^c   Kalyane, Navanath V ^a  

^a BLDE UNIVERSITY   (India)

^b JAWAHARLAL NEHRU TECHNOLOGICAL UNIVERSITY   (India)

^c MANIPAL COLLEGE OF PHARMACEUTICAL SCIENCES   (India)

^d University College of Engineering   (India)

Author keywords

Drug targeting; Interpenetrating polymer network; Ketoprofen; Polymer grafting; Stomach histopathology

Indexed keywords

DRUG-TARGETING; INTERPENETRATING POLYMERS; KETOPROFEN; POLYMER GRAFTING; STOMACH HISTOPATHOLOGY;

ALKALINITY; AMIDES; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY; FOURIER TRANSFORM INFRARED SPECTROSCOPY; FREE RADICAL POLYMERIZATION; FREE RADICALS; GRAFTING (CHEMICAL); INTERPENETRATING POLYMER NETWORKS; NITROGEN; POLYMERS; SCANNING ELECTRON MICROSCOPY; SODIUM; THERMOGRAVIMETRIC ANALYSIS; X RAY DIFFRACTION;

HYDROGELS;

ALGINIC ACID; CARRAGEENAN; KETOPROFEN; NITROGEN; POLYACRYLAMIDE;

ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; CROSS LINKING; DIFFERENTIAL SCANNING CALORIMETRY; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG TARGETING; GELATION; HISTOPATHOLOGY; HYDROGEL; HYDROLYSIS; IN VITRO STUDY; IN VIVO STUDY; INFRARED SPECTROSCOPY; INTERPENETRATING NETWORK HYDROGEL BEAD; INTESTINE; MALE; NONHUMAN; PH; POLYMERIZATION; PRIORITY JOURNAL; RAT; RISK REDUCTION; SCANNING ELECTRON MICROSCOPY; STOMACH EROSION; STOMACH HEMORRHAGE; STOMACH ULCER; SYNTHESIS; THERMOGRAVIMETRY; X RAY DIFFRACTION;

ACRYLAMIDES; ALGINATES; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CARRAGEENAN; DELAYED-ACTION PREPARATIONS; GLUCURONIC ACID; HEXURONIC ACIDS; HYDROGEL; HYDROGEN-ION CONCENTRATION; INTESTINES; KETOPROFEN; MALE; RATS;

EID: 83355163246     PISSN: 00219797     EISSN: 10957103     Source Type: Journal    
DOI: 10.1016/j.jcis.2011.10.025     Document Type: Article

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