-
1
-
-
77956316577
-
Safety and efficacy of ghrelin agonist TZP-101 in relieving symptoms in patients with diabetic gastroparesis: a randomized, placebo-controlled study
-
Ejskjaer N., Dimcevski G., Wo J., Hellstrom P.M., Gormsen L.C., Sarosiek I., et al. Safety and efficacy of ghrelin agonist TZP-101 in relieving symptoms in patients with diabetic gastroparesis: a randomized, placebo-controlled study. Neurogastroenterol Motil 2010, 22:1069-e281.
-
(2010)
Neurogastroenterol Motil
, vol.22
-
-
Ejskjaer, N.1
Dimcevski, G.2
Wo, J.3
Hellstrom, P.M.4
Gormsen, L.C.5
Sarosiek, I.6
-
2
-
-
0033540056
-
Ghrelin is a growth-hormone-releasing acylated peptide from stomach
-
Kojima M., Hosoda H., Date Y., Nakazato M., Matsuo H., Kangawa K. Ghrelin is a growth-hormone-releasing acylated peptide from stomach. Nature 1999, 402:656-660.
-
(1999)
Nature
, vol.402
, pp. 656-660
-
-
Kojima, M.1
Hosoda, H.2
Date, Y.3
Nakazato, M.4
Matsuo, H.5
Kangawa, K.6
-
3
-
-
0033867587
-
Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide
-
Tomasetto C., Karam S.M., Ribieras S., Masson R., Lefebvre O., Staub A., et al. Identification and characterization of a novel gastric peptide hormone: the motilin-related peptide. Gastroenterology 2000, 119:395-405.
-
(2000)
Gastroenterology
, vol.119
, pp. 395-405
-
-
Tomasetto, C.1
Karam, S.M.2
Ribieras, S.3
Masson, R.4
Lefebvre, O.5
Staub, A.6
-
4
-
-
0035083549
-
Growth hormone secretagogue receptor family members and ligands
-
Smith R.G., Leonard R., Bailey A.R., Palyha O., Feighner S., Tan C., et al. Growth hormone secretagogue receptor family members and ligands. Endocrine 2001, 14:9-14.
-
(2001)
Endocrine
, vol.14
, pp. 9-14
-
-
Smith, R.G.1
Leonard, R.2
Bailey, A.R.3
Palyha, O.4
Feighner, S.5
Tan, C.6
-
5
-
-
0033679897
-
Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
-
Date Y., Kojima M., Hosoda H., Sawaguchi A., Mondal M.S., Suganuma T., et al. Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans. Endocrinology 2000, 141:4255-4261.
-
(2000)
Endocrinology
, vol.141
, pp. 4255-4261
-
-
Date, Y.1
Kojima, M.2
Hosoda, H.3
Sawaguchi, A.4
Mondal, M.S.5
Suganuma, T.6
-
6
-
-
72249112599
-
Localization of acyl ghrelin- and des-acyl ghrelin-immunoreactive cells in the rat stomach and their responses to intragastric pH
-
Mizutani M., Atsuchi K., Asakawa A., Matsuda N., Fujimura M., Inui A., et al. Localization of acyl ghrelin- and des-acyl ghrelin-immunoreactive cells in the rat stomach and their responses to intragastric pH. Am J Physiol Gastrointest Liver Physiol 2009, 297:G974-G980.
-
(2009)
Am J Physiol Gastrointest Liver Physiol
, vol.297
-
-
Mizutani, M.1
Atsuchi, K.2
Asakawa, A.3
Matsuda, N.4
Fujimura, M.5
Inui, A.6
-
7
-
-
0034731310
-
Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue
-
Hosoda H., Kojima M., Matsuo H., Kangawa K. Ghrelin and des-acyl ghrelin: two major forms of rat ghrelin peptide in gastrointestinal tissue. Biochem Biophys Res Commun 2000, 279:909-913.
-
(2000)
Biochem Biophys Res Commun
, vol.279
, pp. 909-913
-
-
Hosoda, H.1
Kojima, M.2
Matsuo, H.3
Kangawa, K.4
-
8
-
-
33645857375
-
Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor
-
Toshinai K., Yamaguchi H., Sun Y., Smith R.G., Yamanaka A., Sakurai T., et al. Des-acyl ghrelin induces food intake by a mechanism independent of the growth hormone secretagogue receptor. Endocrinology 2006, 147:2306-2314.
-
(2006)
Endocrinology
, vol.147
, pp. 2306-2314
-
-
Toshinai, K.1
Yamaguchi, H.2
Sun, Y.3
Smith, R.G.4
Yamanaka, A.5
Sakurai, T.6
-
9
-
-
17944379112
-
Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans
-
Ariyasu H., Takaya K., Tagami T., Ogawa Y., Hosoda K., Akamizu T., et al. Stomach is a major source of circulating ghrelin, and feeding state determines plasma ghrelin-like immunoreactivity levels in humans. J Clin Endocrinol Metab 2001, 86:4753-4758.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 4753-4758
-
-
Ariyasu, H.1
Takaya, K.2
Tagami, T.3
Ogawa, Y.4
Hosoda, K.5
Akamizu, T.6
-
10
-
-
0346995397
-
Nutrient inhibition of ghrelin secretion in the fasted rat
-
Gomez G., Englander E.W., Greeley G.H. Nutrient inhibition of ghrelin secretion in the fasted rat. Regul Pept 2004, 117:33-36.
-
(2004)
Regul Pept
, vol.117
, pp. 33-36
-
-
Gomez, G.1
Englander, E.W.2
Greeley, G.H.3
-
11
-
-
77957107899
-
Altered fasting and postprandial plasma ghrelin levels in patients with liver failure are normalized after liver transplantation
-
Diz-Lois M.T., Garcia-Buela J., Suarez F., Sangiao-Alvarellos S., Vidal O., Cordido F. Altered fasting and postprandial plasma ghrelin levels in patients with liver failure are normalized after liver transplantation. Eur J Endocrinol 2010, 163:609-616.
-
(2010)
Eur J Endocrinol
, vol.163
, pp. 609-616
-
-
Diz-Lois, M.T.1
Garcia-Buela, J.2
Suarez, F.3
Sangiao-Alvarellos, S.4
Vidal, O.5
Cordido, F.6
-
12
-
-
0036141195
-
Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations
-
Lee H.M., Wang G., Englander E.W., Kojima M., Greeley G.H. Ghrelin, a new gastrointestinal endocrine peptide that stimulates insulin secretion: enteric distribution, ontogeny, influence of endocrine, and dietary manipulations. Endocrinology 2002, 143:185-190.
-
(2002)
Endocrinology
, vol.143
, pp. 185-190
-
-
Lee, H.M.1
Wang, G.2
Englander, E.W.3
Kojima, M.4
Greeley, G.H.5
-
13
-
-
0035433977
-
A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
-
Cummings D.E., Purnell J.Q., Frayo R.S., Schmidova K., Wisse B.E., Weigle D.S. A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans. Diabetes 2001, 50:1714-1719.
-
(2001)
Diabetes
, vol.50
, pp. 1714-1719
-
-
Cummings, D.E.1
Purnell, J.Q.2
Frayo, R.S.3
Schmidova, K.4
Wisse, B.E.5
Weigle, D.S.6
-
14
-
-
0035082265
-
Circulating ghrelin levels are decreased in human obesity
-
Tschop M., Weyer C., Tataranni P.A., Devanarayan V., Ravussin E., Heiman M.L. Circulating ghrelin levels are decreased in human obesity. Diabetes 2001, 50:707-709.
-
(2001)
Diabetes
, vol.50
, pp. 707-709
-
-
Tschop, M.1
Weyer, C.2
Tataranni, P.A.3
Devanarayan, V.4
Ravussin, E.5
Heiman, M.L.6
-
15
-
-
51149115320
-
Ghrelin secretion is not reduced by increased fat mass during diet-induced obesity
-
Qi X., Reed J.T., Wang G., Han S., Englander E.W., Greeley G.H. Ghrelin secretion is not reduced by increased fat mass during diet-induced obesity. Am J Physiol Regul Integr Comp Physiol 2008, 295:R429-R435.
-
(2008)
Am J Physiol Regul Integr Comp Physiol
, vol.295
-
-
Qi, X.1
Reed, J.T.2
Wang, G.3
Han, S.4
Englander, E.W.5
Greeley, G.H.6
-
16
-
-
14644415905
-
Thiazolidinediones upregulate fatty acid uptake and oxidation in adipose tissue of diabetic patients
-
Boden G., Homko C., Mozzoli M., Showe L.C., Nichols C., Cheung P. Thiazolidinediones upregulate fatty acid uptake and oxidation in adipose tissue of diabetic patients. Diabetes 2005, 54:880-885.
-
(2005)
Diabetes
, vol.54
, pp. 880-885
-
-
Boden, G.1
Homko, C.2
Mozzoli, M.3
Showe, L.C.4
Nichols, C.5
Cheung, P.6
-
17
-
-
70350495216
-
Potent antidiabetic effects of rivoglitazone, a novel peroxisome proliferator-activated receptor-gamma agonist, in obese diabetic rodent models
-
Kanda S., Nakashima R., Takahashi K., Tanaka J., Ogawa J., Ogata T., et al. Potent antidiabetic effects of rivoglitazone, a novel peroxisome proliferator-activated receptor-gamma agonist, in obese diabetic rodent models. J Pharmacol Sci 2009, 111:155-166.
-
(2009)
J Pharmacol Sci
, vol.111
, pp. 155-166
-
-
Kanda, S.1
Nakashima, R.2
Takahashi, K.3
Tanaka, J.4
Ogawa, J.5
Ogata, T.6
-
18
-
-
33745869049
-
Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues
-
LeBrasseur N.K., Kelly M., Tsao T.S., Farmer S.R., Saha A.K., Ruderman N.B., et al. Thiazolidinediones can rapidly activate AMP-activated protein kinase in mammalian tissues. Am J Physiol Endocrinol Metab 2006, 291:E175-E181.
-
(2006)
Am J Physiol Endocrinol Metab
, vol.291
-
-
LeBrasseur, N.K.1
Kelly, M.2
Tsao, T.S.3
Farmer, S.R.4
Saha, A.K.5
Ruderman, N.B.6
-
19
-
-
33750880400
-
Rosiglitazone treatment enhances acute AMP-activated protein kinase-mediated muscle and adipose tissue glucose uptake in high-fat-fed rats
-
Ye J.M., Dzamko N., Hoy A.J., Iglesias M.A., Kemp B., Kraegen E. Rosiglitazone treatment enhances acute AMP-activated protein kinase-mediated muscle and adipose tissue glucose uptake in high-fat-fed rats. Diabetes 2006, 55:2797-2804.
-
(2006)
Diabetes
, vol.55
, pp. 2797-2804
-
-
Ye, J.M.1
Dzamko, N.2
Hoy, A.J.3
Iglesias, M.A.4
Kemp, B.5
Kraegen, E.6
-
20
-
-
33645399063
-
Effect of chronic hyperghrelinemia on ingestive action of ghrelin
-
Wei W., Qi X., Reed J., Ceci J., Wang H.Q., Wang G., et al. Effect of chronic hyperghrelinemia on ingestive action of ghrelin. Am J Physiol Regul Integr Comp Physiol 2006, 290:R803-R808.
-
(2006)
Am J Physiol Regul Integr Comp Physiol
, vol.290
-
-
Wei, W.1
Qi, X.2
Reed, J.3
Ceci, J.4
Wang, H.Q.5
Wang, G.6
-
21
-
-
65649151443
-
Increased expression of receptors for orexigenic factors in nodose ganglion of diet-induced obese rats
-
Paulino G., Barbier de la Serre C., Knotts T.A., Oort P.J., Newman J.W., Adams S.H., et al. Increased expression of receptors for orexigenic factors in nodose ganglion of diet-induced obese rats. Am J Physiol Endocrinol Metab 2009, 296:E898-E903.
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Paulino, G.1
Barbier de la Serre, C.2
Knotts, T.A.3
Oort, P.J.4
Newman, J.W.5
Adams, S.H.6
-
22
-
-
0036787457
-
The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats
-
Date Y., Murakami N., Toshinai K., Matsukura S., Niijima A., Matsuo H., et al. The role of the gastric afferent vagal nerve in ghrelin-induced feeding and growth hormone secretion in rats. Gastroenterology 2002, 123:1120-1128.
-
(2002)
Gastroenterology
, vol.123
, pp. 1120-1128
-
-
Date, Y.1
Murakami, N.2
Toshinai, K.3
Matsukura, S.4
Niijima, A.5
Matsuo, H.6
-
23
-
-
23944474572
-
Ghrelin increases food intake in obese as well as lean subjects
-
Druce M.R., Wren A.M., Park A.J., Milton J.E., Patterson M., Frost G., et al. Ghrelin increases food intake in obese as well as lean subjects. Int J Obes (Lond) 2005, 29:1130-1136.
-
(2005)
Int J Obes (Lond)
, vol.29
, pp. 1130-1136
-
-
Druce, M.R.1
Wren, A.M.2
Park, A.J.3
Milton, J.E.4
Patterson, M.5
Frost, G.6
-
24
-
-
31044451759
-
Mice lacking ghrelin receptors resist the development of diet-induced obesity
-
Zigman J.M., Nakano Y., Coppari R., Balthasar N., Marcus J.N., Lee C.E., et al. Mice lacking ghrelin receptors resist the development of diet-induced obesity. J Clin Invest 2005, 115:3564-3572.
-
(2005)
J Clin Invest
, vol.115
, pp. 3564-3572
-
-
Zigman, J.M.1
Nakano, Y.2
Coppari, R.3
Balthasar, N.4
Marcus, J.N.5
Lee, C.E.6
-
25
-
-
77957274035
-
Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons
-
Briggs D.I., Enriori P.J., Lemus M.B., Cowley M.A., Andrews Z.B. Diet-induced obesity causes ghrelin resistance in arcuate NPY/AgRP neurons. Endocrinology 2010, 151:4745-4755.
-
(2010)
Endocrinology
, vol.151
, pp. 4745-4755
-
-
Briggs, D.I.1
Enriori, P.J.2
Lemus, M.B.3
Cowley, M.A.4
Andrews, Z.B.5
-
26
-
-
77952685648
-
The hyperphagic effect of ghrelin is inhibited in mice by a diet high in fat
-
(76 e1)
-
Gardiner J.V., Campbell D., Patterson M., Kent A., Ghatei M.A., Bloom S.R., et al. The hyperphagic effect of ghrelin is inhibited in mice by a diet high in fat. Gastroenterology 2010, 138:2468-2476. (76 e1).
-
(2010)
Gastroenterology
, vol.138
, pp. 2468-2476
-
-
Gardiner, J.V.1
Campbell, D.2
Patterson, M.3
Kent, A.4
Ghatei, M.A.5
Bloom, S.R.6
-
27
-
-
3442898563
-
Resistance to the orexigenic effect of ghrelin in dietary-induced obesity in mice: reversal upon weight loss
-
Perreault M., Istrate N., Wang L., Nichols A.J., Tozzo E., Stricker-Krongrad A. Resistance to the orexigenic effect of ghrelin in dietary-induced obesity in mice: reversal upon weight loss. Int J Obes Relat Metab Disord 2004, 28:879-885.
-
(2004)
Int J Obes Relat Metab Disord
, vol.28
, pp. 879-885
-
-
Perreault, M.1
Istrate, N.2
Wang, L.3
Nichols, A.J.4
Tozzo, E.5
Stricker-Krongrad, A.6
-
28
-
-
0035514596
-
Ghrelin causes hyperphagia and obesity in rats
-
Wren A.M., Small C.J., Abbott C.R., Dhillo W.S., Seal L.J., Cohen M.A., et al. Ghrelin causes hyperphagia and obesity in rats. Diabetes 2001, 50:2540-2547.
-
(2001)
Diabetes
, vol.50
, pp. 2540-2547
-
-
Wren, A.M.1
Small, C.J.2
Abbott, C.R.3
Dhillo, W.S.4
Seal, L.J.5
Cohen, M.A.6
-
29
-
-
0036347936
-
Insulin regulates plasma ghrelin concentration
-
Saad M.F., Bernaba B., Hwu C.M., Jinagouda S., Fahmi S., Kogosov E., et al. Insulin regulates plasma ghrelin concentration. J Clin Endocrinol Metab 2002, 87:3997-4000.
-
(2002)
J Clin Endocrinol Metab
, vol.87
, pp. 3997-4000
-
-
Saad, M.F.1
Bernaba, B.2
Hwu, C.M.3
Jinagouda, S.4
Fahmi, S.5
Kogosov, E.6
-
30
-
-
42149092589
-
Changes of ghrelin following oral glucose tolerance test in obese children with insulin resistance
-
Wang X.M., Jiang Y.J., Liang L., Du L.Z. Changes of ghrelin following oral glucose tolerance test in obese children with insulin resistance. World J Gastroenterol 2008, 14:1919-1924.
-
(2008)
World J Gastroenterol
, vol.14
, pp. 1919-1924
-
-
Wang, X.M.1
Jiang, Y.J.2
Liang, L.3
Du, L.Z.4
-
31
-
-
4644276618
-
Effect of uncontrolled diabetes on plasma ghrelin concentrations and ghrelin-induced feeding
-
Gelling R.W., Overduin J., Morrison C.D., Morton G.J., Frayo R.S., Cummings D.E., et al. Effect of uncontrolled diabetes on plasma ghrelin concentrations and ghrelin-induced feeding. Endocrinology 2004, 145:4575-4582.
-
(2004)
Endocrinology
, vol.145
, pp. 4575-4582
-
-
Gelling, R.W.1
Overduin, J.2
Morrison, C.D.3
Morton, G.J.4
Frayo, R.S.5
Cummings, D.E.6
-
32
-
-
76049105515
-
Preprandial single oral dose of sitagliptin does not affect circulating ghrelin and gastrin levels in normal subjects
-
Huang C.L., Hsu C.H., Huang K.C., Su H.Y., Weng S.F. Preprandial single oral dose of sitagliptin does not affect circulating ghrelin and gastrin levels in normal subjects. Pharmacology 2010, 85:131-135.
-
(2010)
Pharmacology
, vol.85
, pp. 131-135
-
-
Huang, C.L.1
Hsu, C.H.2
Huang, K.C.3
Su, H.Y.4
Weng, S.F.5
|