Functional analysis of interaction sites on the N-terminal domain of clathrin heavy chain

Traffic

Volumn 13, Issue 1, 2012, Pages 70-81

  Willox, Anna K ^a   Royle, Stephen J ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

Adaptors; AP 2; Beta propeller; Clathrin; Clathrin box motifs; Endocytosis; Transferrin; Vesicle

Indexed keywords

ADAPTOR PROTEIN; CLATHRIN HEAVY CHAIN; COMPLEMENTARY DNA; GREEN FLUORESCENT PROTEIN; SHORT HAIRPIN RNA;

ARTICLE; BINDING SITE; CELL MEMBRANE TRANSPORT; CELL STRAIN HEK293; CONTROLLED STUDY; ENDOCYTOSIS; FLOW CYTOMETRY; HELA CELL; HUMAN; HUMAN CELL; MEMBRANE VESICLE; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; RNA INTERFERENCE; SEQUENCE ANALYSIS;

ADAPTOR PROTEIN COMPLEX 2; AMINO ACID SEQUENCE; ANIMALS; BINDING SITES; CELL MEMBRANE; CLATHRIN HEAVY CHAINS; ENDOCYTOSIS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; GREEN FLUORESCENT PROTEINS; HEK293 CELLS; HELA CELLS; HUMANS; MICROSCOPY, CONFOCAL; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN TRANSPORT; RECOMBINANT FUSION PROTEINS; SEQUENCE ALIGNMENT; TRANSFECTION;

EID: 83255187157     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2011.01289.x     Document Type: Article

References (47)

1. Brodsky FM, Chen CY, Knuehl C, Towler MC, Wakeham DE. Biological basket weaving: formation and function of clathrin-coated vesicles. Annu Rev Cell Dev Biol 2001;17:517-568.
2. Traub LM. Tickets to ride: selecting cargo for clathrin-regulated internalization. Nat Rev Mol Cell Biol 2009;10:583-596.
3. Unanue ER, Ungewickell E, Branton D. The binding of clathrin triskelions to membranes from coated vesicles. Cell 1981;26:439-446.
4. Hirst J, Robinson MS. Clathrin and adaptors. Biochim Biophys Acta 1998;1404:173-193.
5. Vigers GP, Crowther RA, Pearse BM. Location of the 100 kd-50 kd accessory proteins in clathrin coats. EMBO J 1986;5:2079-2085.
6. Vigers GP, Crowther RA, Pearse BM. Three-dimensional structure of clathrin cages in ice. EMBO J 1986;5:529-534.
7. Cheng Y, Boll W, Kirchhausen T, Harrison SC, Walz T. Cryo-electron tomography of clathrin-coated vesicles: structural implications for coat assembly. J Mol Biol 2007;365:892-899.
8. Motley A, Bright NA, Seaman MN, Robinson MS. Clathrin-mediated endocytosis in AP-2-depleted cells. J Cell Biol 2003;162:909-918.
9. Reider A, Wendland B. Endocytic adaptors-social networking at the plasma membrane. J Cell Sci 2011;124:1613-1622.
10. ter Haar E, Musacchio A, Harrison SC, Kirchhausen T. Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker. Cell 1998;95:563-573.
11. Fotin A, Cheng Y, Sliz P, Grigorieff N, Harrison SC, Kirchhausen T, Walz T. Molecular model for a complete clathrin lattice from electron cryomicroscopy. Nature 2004;432:573-579.
12. ter Haar E, Harrison SC, Kirchhausen T. Peptide-in-groove interactions link target proteins to the beta-propeller of clathrin. Proc Natl Acad Sci U S A 2000;97:1096-1100.
13. Goodman OB Jr, Krupnick JG, Gurevich VV, Benovic JL, Keen JH. Arrestin/clathrin interaction. Localization of the arrestin binding locus to the clathrin terminal domain. J Biol Chem 1997;272: 15017-15022.
14. Drake MT, Traub LM. Interaction of two structurally distinct sequence types with the clathrin terminal domain beta-propeller. J Biol Chem 2001;276:28700-28709.
15. Miele AE, Watson PJ, Evans PR, Traub LM, Owen DJ. Two distinct interaction motifs in amphiphysin bind two independent sites on the clathrin terminal domain beta-propeller. Nat Struct Mol Biol 2004;11:242-248.
16. Kang DS, Kern RC, Puthenveedu MA, von Zastrow M, Williams JC, Benovic JL. Structure of an arrestin2-clathrin complex reveals a novel clathrin binding domain that modulates receptor trafficking. J Biol Chem 2009;284:29860-29872.
17. Kirchhausen T. Clathrin adaptors really adapt. Cell 2002;109:413-416.
18. Dell'Angelica EC, Klumperman J, Stoorvogel W, Bonifacino JS. Association of the AP-3 adaptor complex with clathrin. Science 1998;280:431-434.
19. Krupnick JG, Goodman OB Jr, Keen JH, Benovic JL. Arrestin/clathrin interaction. Localization of the clathrin binding domain of nonvisual arrestins to the carboxy terminus. J Biol Chem 1997;272: 15011-15016.
20. Dell'Angelica EC. Clathrin-binding proteins: got a motif? Join the network! Trends Cell Biol 2001;11:315-318.
21. Edeling MA, Mishra SK, Keyel PA, Steinhauser AL, Collins BM, Roth R, Heuser JE, Owen DJ, Traub LM. Molecular switches involving the AP-2 beta2 appendage regulate endocytic cargo selection and clathrin coat assembly. Dev Cell 2006;10:329-342.
22. Keyel PA, Thieman JR, Roth R, Erkan E, Everett ET, Watkins SC, Heuser JE, Traub LM. The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis. Mol Biol Cell 2008;19: 5309-5326.
23. Lundmark R, Carlsson SR. The beta-appendages of the four adaptor-protein (AP) complexes: structure and binding properties, and identification of sorting nexin 9 as an accessory protein to AP-2. Biochem J 2002;362:597-607.
24. Owen DJ, Vallis Y, Pearse BM, McMahon HT, Evans PR. The structure and function of the beta 2-adaptin appendage domain. EMBO J 2000; 19:4216-4227.
25. Knuehl C, Chen CY, Manalo V, Hwang PK, Ota N, Brodsky FM. Novel binding sites on clathrin and adaptors regulate distinct aspects of coat assembly. Traffic 2006;7:1688-1700.
26. Schmid EM, McMahon HT. Integrating molecular and network biology to decode endocytosis. Nature 2007;448:883-888.
27. Collette JR, Chi RJ, Boettner DR, Fernandez-Golbano IM, Plemel R, Merz AJ, Geli MI, Traub LM, Lemmon SK. Clathrin functions in the absence of the terminal domain binding site for adaptor-associated clathrin-box motifs. Mol Biol Cell 2009;20:3401-3413.
28. Baggett JJ, Wendland B. Clathrin function in yeast endocytosis. Traffic 2001;2:297-302.
29. Yeung BG, Phan HL, Payne GS. Adaptor complex-independent clathrin function in yeast. Mol Biol Cell 1999;10:3643-3659.
30. Hood FE, Royle SJ. Functional equivalence of the clathrin heavy chains CHC17 and CHC22 in endocytosis and mitosis. J Cell Sci 2009;122:2185-2190.
31. Royle SJ, Bright NA, Lagnado L. Clathrin is required for the function of the mitotic spindle. Nature 2005;434:1152-1157.
32. Royle SJ, Lagnado L. Trimerisation is important for the function of clathrin at the mitotic spindle. J Cell Sci 2006;119:4071-4078.
33. Borner GH, Harbour M, Hester S, Lilley KS, Robinson MS. Comparative proteomics of clathrin-coated vesicles. J Cell Biol 2006;175:571-578.
34. Nesterov A, Carter RE, Sorkina T, Gill GN, Sorkin A. Inhibition of the receptor-binding function of clathrin adaptor protein AP-2 by dominant-negative mutant mu2 subunit and its effects on endocytosis. EMBO J 1999;18:2489-2499.
35. Motley AM, Berg N, Taylor MJ, Sahlender DA, Hirst J, Owen DJ, Robinson MS. Functional analysis of AP-2 {alpha} and {micro}2 subunits. Mol Biol Cell 2006;17:5298-5308.
36. Glaser F, Pupko T, Paz I, Bell RE, Bechor-Shental D, Martz E, Ben-Tal N. ConSurf: identification of functional regions in proteins by surface-mapping of phylogenetic information. Bioinformatics 2003; 19:163-164.
37. Brodsky FM. Living with clathrin: its role in intracellular membrane traffic. Science 1988;242:1396-1402.
38. Li Q, Lau A, Morris TJ, Guo L, Fordyce CB, Stanley EF. A syntaxin 1, Galpha(o), and N-type calcium channel complex at a presynaptic nerve terminal: analysis by quantitative immunocolocalization. J Neurosci 2004;24:4070-4081.
39. Taylor MJ, Perrais D, Merrifield CJ. A high precision survey of the molecular dynamics of mammalian clathrin-mediated endocytosis. PLoS Biol 2011;9:e1000604.
40. Liu SH, Marks MS, Brodsky FM. A dominant-negative clathrin mutant differentially affects trafficking of molecules with distinct sorting motifs in the class II major histocompatibility complex (MHC) pathway. J Cell Biol 1998;140:1023-1037.
41. Wilde A, Beattie EC, Lem L, Riethof DA, Liu SH, Mobley WC, Soriano P, Brodsky FM. EGF receptor signaling stimulates SRC kinase phosphorylation of clathrin, influencing clathrin redistribution and EGF uptake. Cell 1999;96:677-687.
42. Moskowitz HS, Yokoyama CT, Ryan TA. Highly cooperative control of endocytosis by clathrin. Mol Biol Cell 2005;16:1769-1776.
43. Doyon JB, Zeitler B, Cheng J, Cheng AT, Cherone JM, Santiago Y, Lee AH, Vo TD, Doyon Y, Miller JC, Paschon DE, Zhang L, Rebar EJ, Gregory PD, Urnov FD, et al. Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells. Nat Cell Biol 2011;13:331-337.
44. von Kleist L, Stahlschmidt W, Bulut H, Gromova K, Puchkov D, Robertson MJ, Macgregor KA, Tomlin N, Pechstein A, Chau N, Chircop M, Sakoff J, von Kries JP, Saenger W, Krausslich HG, et al. Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition. Cell 2011;146:471-484.
45. Zhuo Y, Ilangovan U, Schirf V, Demeler B, Sousa R, Hinck AP, Lafer EM. Dynamic interactions between clathrin and locally structured elements in a disordered protein mediate clathrin lattice assembly. J Mol Biol 2010;404:274-290.
46. Morgan JR, Prasad K, Hao W, Augustine GJ, Lafer EM. A conserved clathrin assembly motif essential for synaptic vesicle endocytosis. J Neurosci 2000;20:8667-8676.
47. Booth DG, Hood FE, Prior IA, Royle SJ. A TACC3/ch-TOG/clathrin complex stabilises kinetochore fibres by inter-microtubule bridging. EMBO J 2011;30:906-919.