Identification of bound nitro musk-protein adducts in fish liver by gas chromatography-mass spectrometry: Biotransformation, dose-response and toxicokinetics of nitro musk metabolites protein adducts in trout liver as biomarkers of exposure

Aquatic Toxicology

Volumn 106-107, Issue , 2012, Pages 164-172

  Mottaleb, M Abdul ^a   Osemwengie, Lantis I ^b   Islam, M Rafiq ^a   Sovocool, G Wayne ^b  

^a NORTHWEST MISSOURI STATE UNIVERSITY   (United States)

^b U S ENVIRONMENTAL PROTECTION AGENCY   (United States)

Author keywords

Biotransformation; Dose response and toxicokinetics biomarker of exposure; Fish liver; GC MS; Nitro musk proteins adduct

Indexed keywords

CYSTEINE; HEXANE; MUSK KETONE; MUSK XYLENE;

AMINO ACID; BIOMARKER; BIOTRANSFORMATION; FISH; GAS CHROMATOGRAPHY; HYDROLYSIS; MASS SPECTROMETRY; METABOLITE; POLLUTION EXPOSURE; PROTEIN;

ALKALINITY; ARTICLE; BIOTRANSFORMATION; COMPLEX FORMATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GAS CHROMATOGRAPHY; HALF LIFE TIME; HYDROLYSIS; ION MONITORING; LIMIT OF DETECTION; LIVER TOXICITY; MASS SPECTROMETRY; METABOLITE; NONHUMAN; PRIORITY JOURNAL; PROTEIN ADDUCT; PROTEIN BINDING; REDUCTION; SIGNAL NOISE RATIO; STANDARD; TOXICOKINETICS; TROUT;

BIOLOGICAL MARKERS; BIOTRANSFORMATION; DOSE-RESPONSE RELATIONSHIP, DRUG; ENVIRONMENTAL EXPOSURE; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; LIMIT OF DETECTION; LIVER; WATER POLLUTANTS, CHEMICAL; XYLENES;

SALMONIDAE;

EID: 83255163177     PISSN: 0166445X     EISSN: 18791514     Source Type: Journal    
DOI: 10.1016/j.aquatox.2011.11.010     Document Type: Article

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