Pharmacodynamic modeling of propofol-induced tidal volume depression in children

Journal of Clinical Monitoring and Computing

Volumn 25, Issue 4, 2011, Pages 275-284

  Hahn, Jin Oh ^a   Khosravi, Sara ^b   Dosani, Maryam ^b   Dumont, Guy A ^b   Ansermino, J Mark ^b  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Anesthesia; Pediatrics; Pharmacodynamics; Propofol; Respiratory depression; Tidal volume

Indexed keywords

ANESTHESIA; BODY WEIGHT; COVARIATES; GASTROINTESTINAL ENDOSCOPIES; MIXED EFFECTS; MODELING APPROACH; PERCENTAGE ERROR; PHARMACODYNAMIC MODELS; PHARMACOKINETIC MODEL; PLASMA CONCENTRATION; PREDICTIVE PERFORMANCE; PROPOFOL; REAL TIME; RESPIRATORY DEPRESSION; RESPIRATORY PARAMETERS; RESPIRATORY RATE; ROOT-MEAN-SQUARED; SPONTANEOUS BREATHING; TIDAL VOLUME;

ANTHROPOMETRY; ATMOSPHERIC COMPOSITION; CARBON DIOXIDE; ERRORS; PEDIATRICS;

PHARMACODYNAMICS;

PROPOFOL;

ADOLESCENT; AGE; ANALYTICAL ERROR; ARTICLE; BODY WEIGHT; BREATHING MECHANICS; BREATHING RATE; CHEMICAL MODEL; CHILD; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DOSE REGIMEN; DRUG EFFECT; DRUG INFUSION; END TIDAL CARBON DIOXIDE TENSION; GASTROINTESTINAL ENDOSCOPY; HUMAN; INFUSION RATE; LOADING DRUG DOSE; MAJOR CLINICAL STUDY; MINUTE VOLUME; PATIENT CODING; PEDIATRIC ANESTHESIA; PHARMACODYNAMICS; PHARMACOLOGICAL PARAMETERS; PREDICTION; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; RESIDUE ANALYSIS; RESPIRATION DEPRESSION; RESPIRATORY TRACT PARAMETERS; TIDAL VOLUME;

ADOLESCENT; ANESTHETICS, INTRAVENOUS; CARBON DIOXIDE; CHILD; DEPRESSION, CHEMICAL; HUMANS; INFUSIONS, INTRAVENOUS; MODELS, BIOLOGICAL; PROPOFOL; RESPIRATORY RATE; TIDAL VOLUME;

EID: 83155192182     PISSN: 13871307     EISSN: 15732614     Source Type: Journal    
DOI: 10.1007/s10877-011-9306-0     Document Type: Article

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