Antiulcer effect of epoxy-carvone

Revista Brasileira de Farmacognosia

Volumn 22, Issue 1, 2011, Pages 144-149

  Siqueira, Bruna P J ^a   Menezes, Crislaine T ^a   Silva, Jaciara P ^a   de Sousa, Damião P ^a   Batista, Josemar S ^a  

^a FEDERAL UNIVERSITY OF SERGIPE   (Brazil)

Author keywords

Epoxy carvone essential oil ethanol induced gastric ulcer gastroprotective activity indomethacin induced gastric ulcer monoterpene

Indexed keywords

ANTIULCER AGENT; CARVONE; EPOXYCARVONE; ESSENTIAL OIL; INDOMETACIN; N(G) NITROARGININE METHYL ESTER; NITRIC OXIDE; PROSTAGLANDIN; RANITIDINE; TERPENE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIULCER ACTIVITY; ARTICLE; CHEMICAL MODIFICATION; COMPETITIVE INHIBITION; CONTROLLED STUDY; DRUG ACTIVITY; DRUG EFFICACY; MALE; NONHUMAN; PROSTAGLANDIN SYNTHESIS; PROTECTION; PYLORUS LIGATION; RAT; STOMACH MUCOSA; STOMACH SECRETION; STOMACH ULCER; THERAPY EFFECT;

EID: 83155175693     PISSN: 0102695X     EISSN: None     Source Type: Journal    
DOI: 10.1590/S0102-695X2011005000172     Document Type: Article

References (26)

1. Alkohafi A, Atta AH 1999. Pharmacological screening of the anti-ulcerogenic effects of some Jordanian medicinal plants in rats. J Ethnopharmacol 67: 341-345.
2. Arruda TA, Antunes RMP, Catão RMR, Lima EO, De Sousa DP, Nunes XP, Pereira MSV, Barbosa-Filho JM, Da Cunha EVL 2006. Preliminary study of the antimicrobial activity of Mentha x villosa Hudson essential oil, rotundifolone and its analogues. Rev Bras Farmacogn 16: 307-311.
3. Barbosa PPP, Ramos CP 1992. Studies on the antiulcer activity of the essential oil of Hyptis mutabilis Briq. in rats. Phytother Res 62: 114-115.
4. De Sousa DP, Nóbrega FFF, Claudino FS, Almeida RN, Leite JR, Mattei R 2007. Pharmacological effects of the monoterpene α,β-epoxy-carvone in mice. Rev Bras Farmacogn 17: 170-175.
5. Esteves I, Souza IR, Rodrigues M, Cardoso LGV, Santos LS, Sertie JAA, Perazzo FF, Lima LM, Schneedorf JM, Bastos JK, Carvalho JCT 2005. Gastric antiulcer and anti-inflammatory activities of the essential oil from Casearia sylvestris Sw. J Ethnopharmacol 101: 191-196.
6. Falcão HS, Mariath IR, Diniz MF, Batista LM, Barbosa-Filho JM 2008. Plants of the American continent with antiulcer activity. Phytomedicine 15: 132-146.
7. Hiruma-Lima CA, Gracioso JS, Nunnes DS, Brito ARMS 1999. Effects of an essential oil from the bark of Croton cajucara Benth on experimental gastric ulcer models in rats and mice. J Pharm Pharmacol 51: 341-346.
8. Iacobellis NS, Cantore PL, Capasso F, Senatore F 2005. Antibacterial activity of Cuminum cyminum L. and Carum carvi L. essential oils. J Agr Food Chem 53: 57-61.
9. Jirovetz L, Buchbauer G, Shafi PM, Abraham GT 2001. Analysis of the essential oil of the roots of the medicinal plant Kaempferia galanga L. (Zingiberaceae) from South-India. Acta Pharm Turcica 43: 107-110.
10. Lindquist N, Battiste MA, Whitten WM, Williams NH, Strekowski L 1985. Trans-carvone oxide, a monoterpene epoxide from the fragrance of Catasetum. Phytochemistry 24: 863-865.
11. Maria AO, Donadel O, Wendel GH, Guzman JA, Guerreiro E, Giordano OS 2000. Gastric anti-ulcer activity of several α,β-unsaturated carbonyl compounds in rats. Biol Pharmac Bull 23: 555-557.
12. Matsuda H, Pongpiriyadacha Y, Morikawa T, Ochi M, Yoshikawa M 2003. Gastroprotective effects of phenylpropanoids from the rhizomes of Alpinia galanga in rats: structural requirements and mode of action. Eur J Pharmacol 471: 59-67.
13. Matsunaga T, Hasegawa C, Kawasuji T, Suzuki H, Saito H, Takahashi R, Tsukanoto H, Morikawa T, Akiyama T 2000. Isolation of the antiulcer compound in essential oil from the leaves of Cryptomeria japonica. Biol Pharm Bull 23: 595-598.
14. Moraes TM, Kushima H, Moleiro FC, Santos RC, Rocha LR, Marques MO, Vilegas W, Hiruma-Lima CA 2009. Effects of limonene and essential oil from Citrus aurantium on gastric mucosa: role of prostaglandins and gastric mucus secretion. Chem Biol Interact 180: 499-505.
15. Murakami I, Satoh H, Asano S, Maeda R 1996. Role of capsaicinsensitive sensory and nitric oxide in the protective effect of lansoprazole, a prompt pump inhibitor, on the gastric mucosa in rats. Jpn J Pharmacol 72: 137-147.
16. Rees DD, Palmer RM, Schulz R, Hodson, HF, Moncada S 1990. Characterization of three inhibitors of endothelial nitric oxide in vitro and in vivo. Br J Pharmacol 101: 746-752.
17. Robert A, Nezamis JE, Lancaster C, Hanchar AJ 1979. Cytoprotection by prostaglandins in rats. Prevention of gastric necrosis produced by alcohol, HCl, NaOH, hypertonic NaCl, and thermal injury. Gastroenterology 77: 433-443.
18. Santin JR, Lemos M, Klein-Júnior LC, Machado ID, Costa P, de Oliveira AP, Tilia C, de Souza JP, de Sousa JP, Bastos JK, De Andrade SF 2011. Gastroprotective activity of essential oil of the Syzygium aromaticum and its major component eugenol in different animal models. Naunyn Schmiedebergs Arch Pharmacol 383: 149-158.
19. Santos FA, Silva RM, Campos AR, De Araujo RP, Lima-Junior RC, Rao VS 2004. 1,8-cineole (eucalyptol), a monoterpene oxide attenuates the colonic damage in rats on acute TNBS-colitis. Food Chem Toxicol 42: 579-584.
20. Santos RB, Brocksom TJ, Broksom U 1997. A convenient deoxygenation of α,β-epoxy ketones to enones. Tetrahedron Lett 38: 745-748.
21. Shay H, Komarov SA, Fels SS, Meranze D, Gruenstein M, Siplet H 1945. A simple method for the uniform production of gastric ulceration in the rat. Gastroenterology 5: 43-61.
22. Silva MI, Moura BA, Neto MR, Tomé AR, Rocha NF, de Carvalho AM, Macêdo DS, Vasconcelos SM, de Sousa DP, Viana GS, de Sousa FC 2009. Gastroprotective activity of isopulegol on experimentally induced gastric lesions in mice: investigation of possible mechanisms of action. Naunyn Schmiedebergs Arch Pharmacol 380: 233-245.
23. Szabo S, Brown A 1987. Prevention of ethanol-induced vascular injury and gastric mucosal lesions by sucralfate and its components: possible role of endogenous sulfhydryls. Proc Soc Exp Biol Med 185: 493-497.
24. Szabo S, Trier JS, Frankel PW 1981. Sulfhydryl compounds may mediate gastric cytoprotection. Science 214: 200-202.
25. Wallace JL, Granger DN 1996. The cellular and molecular basis of gastric mucosal defense. FASEB J 10: 731-740.
26. Yang YX, Lewis JD, Epstein S, Metz DC 2006. Long-term proton pump inhibitor therapy and risk of hip fracture. JAMA 296: 2947-2953.