Hypolipidemic and antioxidant activity of aqueous extract of monascus purpureus fermented indian rice in high cholesterol diet fed rats

Turkish Journal of Medical Sciences

Volumn 41, Issue 1, 2011, Pages 25-32

  Rajasekaran, Aiyalu ^a   Kalaivani, Muthusamy ^a  

^a KMCH COLLEGE OF PHARMACY   (India)

Author keywords

Antioxidant; DPPH; Hypolipidemic; Lipid peroxidation

Indexed keywords

ANTIOXIDANT; CATALASE; CHOLESTEROL; GLUTATHIONE; HIGH DENSITY LIPOPROTEIN; LOW DENSITY LIPOPROTEIN; METAL CHELATE; MEVINOLIN; MONASCUS PURPUREUS FERMENTED INDIAN RICE EXTRACT; SCAVENGER; SUPEROXIDE DISMUTASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; ARTICLE; CHELATION; CHOLESTEROL DIET; CONTROLLED STUDY; DOSE RESPONSE; DRUG ACTIVITY; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG SCREENING; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME BLOOD LEVEL; FERMENTED PRODUCT; HYPERCHOLESTEROLEMIA; HYPOLIPIDEMIC ACTIVITY; IC 50; IN VITRO STUDY; IN VIVO STUDY; LIPID PEROXIDATION; LIVER LEVEL; MALE; MONASCUS; NONHUMAN; OXIDATIVE STRESS; RAT; RICE;

EID: 83155172580     PISSN: 13000144     EISSN: None     Source Type: Journal    
DOI: 10.3906/sag-1001-533     Document Type: Article

References (25)

1. Botto N, Rizza A, Colombo MG. Evidence for DNA damage in patients with coronary artery disease. Mutation Research 2001; 493: 23-30.
2. Plachta H, Barmikowska E, Obara A. Lipid peroxides in blood from patients with atherosclerosis of coronary and peripheral artries. Clin Chim Acta 1992; 211: 101-12.
3. Sung Y-H. Chinese Technology in the Seventeenth Century. University Park: The Pennsylvania State University Press 1966.
4. Endo A, Monacolin K. A new hypocholesterolemic agent that specifically inhibits 3-hydroxy-3-methylglutaryl coenzyme A reductase. J Antibiotics 1980; 33930: 334-36.
5. Wong RWK, Rabie B. Chinese red yeast rice (Monascus purpureus- fermented rice) promotes bone formation. Chinese Medicine 2008; 3: 4.
6. Jeon T, Hwang SG, Hirai S, Matsui T, Yano H, Kawada T et al. Red yeast rice extracts suppress adipogenesis by downregulating adipogenic transcription factors and gene expression in 3T3-L1 cells. Life Sciences 2004; 75: 3195-203.
7. Singh SK, PK Rai, D Jaiswal, G Watal. Evidence-based critical evaluation of glycemic potential of Cynodon dactylon. eCAM 2008; 5: 415-20.
8. Potchoo Y, Guissou IP, Lompo M, Sakie E, Yaro B. Antioxidant activity of aqueous methanol and ethylacetate extract of leaves of Annona senegalensis pers from Togo versus the one originates from Burkina Faso. International Journal of Pharmacology 2008; 4: 120-24.
9. Malterud KE, Farbrot TL, Huse AE, Sund RB. Antioxidant and radical scavenging effects of anthraquinones and anthrones. Pharmacolog 1993; 47: 77-85.
10. Veerapur VP, Prabhakar KR, VK Parihar, Machendar Reddy Kandadi, Ramakrishana S, Mishra B et al. Ficus racemosa stem bark extract: a potent antioxidant and a probable natural radioprotector. eCAM 2009; 6: 317-24.
11. Psotová J, Lasovský J, Vičar J. Metal-chelating properties, electrochemical behavior, scavenging and cytoprotective activities of six natural phenolics. Biomed Papers 2003; 47: 147-53.
12. Ellman GL. Tissue sulfhydryl group. Arch Biochem Biophys. 1959; 82: 70-77.
13. Miller NJ, Rice-Evans C, Davies MJ, Gopinathan V, Milner A. A novel method for measuring antioxidant capacity and its application to monitoring the antioxidant status in premature neonates. Clin Sci (Lond) 1993; 84: 407-12.
14. Muralikrishnan D, Binu T, Bala VM. Antiparkinson Drug - Mucuna pruriens shows antioxidant and metal chelating activity. Phytother Res 2008; 22: 6-11.
15. Joharapurkar AA, Zambad SP, Wanjari MM, Umathe SN. In vivo evaluation of antioxidant activity of alcoholic extract of Rubia cordifolia linn. and its influence on ethanol-induced immunosuppression. Indian Journal of Pharmacology 2003; 35: 232-36.
16. Stocks J, Dormandy TL. Autooxidation of human red cell lipids induced by hydrogen peroxide. Br J Hematol 1971; 20: 95-111.
17. Kakkar P, Dos B, Viswnathan P. A modified spectrophotometric assay of superoxide dismutase. Indian J Biochem 1984; 21: 130-32.
18. Sinha AK. Colormetric assay of catalase. Anal Bioche 1972; 47: 389-94.
19. Gul M, Kutay FZ, Temocin S, Hanninen O. Cellular and clinical implications of glutathione. Indian J Exp Biol 2000; 38: 625-634.
20. Heber D, Yip I, Ashley JM, Elashoff DA, Elashoff RM, Go VL. Cholesterol-lowering effects of a proprietary Chinese red-yeastrice dietary supplement. American Journal of Clinical Nutrition 1999; 69: 231-36.
21. Czerwinski J, Bartnikowska E, Leotowiz H, Lange E, Leontowicz M, Katrich E et al. Oat (Avena sativa L.) and amaranth (Amaranthus hypochondriacus) meals positively affect plasma lipid profile in rats fed cholesterol containing diets. Journal of Nutritional Biochemistry 2004; 15: 622-29.
22. Kishida T, Nogami H, Ogawa H, Ebihara K. The hypocholesterolemic effect of high amylase corn starch in rats is mediated by an enlarged bile acid pool and increased fecal bile acid excretion, not by cecal fermented products. Journal of Nutrition 2002; 132: 2519-24.
23. Carew TE, Koschinsky T, Mayers SB, Steinberg D. A mechanism by which high-density lipoproteins may slow the atherogenic process. Lancet 1979; 1: 1315-17.
24. Bowry VW, Stanley KK, Stocker R. High density lipoprotein is the major of lipid hydroperoxides in human blood plasma fasting donors. Proceedings of the National Academy of Sciences of the United States of America 1992; 89: 10316-20.
25. Opoku AR, Maseko NF, Terblanche SE. The in vitro antioxidative activity of some traditional Zulu medicinal plants. Phytother Res 2002; 16: 51-56.