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Volumn 306, Issue 21, 2011, Pages 2367-2374

Antiplatelet and anticoagulant therapy in patients with gastrointestinal bleeding: An 86-year-old woman with peptic ulcer disease

Author keywords

[No Author keywords available]

Indexed keywords

ACETYLSALICYLIC ACID; CLOPIDOGREL; DABIGATRAN; ESOMEPRAZOLE; FAMOTIDINE; HEMOGLOBIN; HISTAMINE H2 RECEPTOR ANTAGONIST; MISOPROSTOL; PANTOPRAZOLE; PLACEBO; PROTON PUMP INHIBITOR; WARFARIN;

EID: 83055182078     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2011.1653     Document Type: Conference Paper
Times cited : (23)

References (79)
  • 1
    • 3042651139 scopus 로고    scopus 로고
    • Grading quality of evidence and strength of recommendations
    • GRADE Working Group
    • Atkins D, Best D, Briss PA, et al. GRADE Working Group. Grading quality of evidence and strength of recommendations. BMJ. 2004;328(7454):1490.
    • (2004) BMJ , vol.328 , Issue.7454 , pp. 1490
    • Atkins, D.1    Best, D.2    Briss, P.A.3
  • 2
    • 33646552429 scopus 로고    scopus 로고
    • Complicated and uncomplicated peptic ulcers in a Danish county 1993-2002: A population-based cohort study
    • DOI 10.1111/j.1572-0241.2006.00518.x
    • Lassen A, Hallas J, Schaffalitzky de Muckadell OB. Complicated and uncomplicated peptic ulcers in a Danish county 1993-2002: a population-based cohort study. Am J Gastroenterol. 2006;101(5):945-953. (Pubitemid 43725306)
    • (2006) American Journal of Gastroenterology , vol.101 , Issue.5 , pp. 945-953
    • Lassen, A.1    Hallas, J.2    De Muckadell, O.B.S.3
  • 3
    • 0036791745 scopus 로고    scopus 로고
    • Hospitalization and mortality rates from peptic ulcer disease and GI bleeding in the 1990s: Relationship to sales of nonsteroidal anti-inflammatory drugs and acid suppression medications
    • Lewis JD, Bilker WB, Brensinger C, Farrar JT, Strom BL. Hospitalization and mortality rates from peptic ulcer disease and GI bleeding in the 1990s: relationship to sales of nonsteroidal anti-inflammatory drugs and acid suppression medications. Am J Gastroenterol. 2002;97(10):2540-2549.
    • (2002) Am J Gastroenterol , vol.97 , Issue.10 , pp. 2540-2549
    • Lewis, J.D.1    Bilker, W.B.2    Brensinger, C.3    Farrar, J.T.4    Strom, B.L.5
  • 4
    • 74849114254 scopus 로고    scopus 로고
    • International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding
    • International Consensus Upper Gastrointestinal Bleeding Conference Group
    • Barkun AN, Bardou M, Kuipers EJ, et al. International Consensus Upper Gastrointestinal Bleeding Conference Group. International consensus recommendations on the management of patients with nonvariceal upper gastrointestinal bleeding. Ann Intern Med. 2010;152(2):101-113.
    • (2010) Ann Intern Med , vol.152 , Issue.2 , pp. 101-113
    • Barkun, A.N.1    Bardou, M.2    Kuipers, E.J.3
  • 6
    • 33845304337 scopus 로고    scopus 로고
    • Trends in management and outcomes of acute nonvariceal upper gastrointestinal bleeding: 1993-2003
    • Targownik LE, Nabalamba A. Trends in management and outcomes of acute nonvariceal upper gastrointestinal bleeding: 1993-2003. Clin Gastroenterol Hepatol. 2006;4(12):1459-1466.
    • (2006) Clin Gastroenterol Hepatol , vol.4 , Issue.12 , pp. 1459-1466
    • Targownik, L.E.1    Nabalamba, A.2
  • 7
    • 77954271262 scopus 로고    scopus 로고
    • Use of endoscopy for management of acute upper gastrointestinal bleeding in the UK: Results of a nationwide audit
    • Hearnshaw SA, Logan RF, Lowe D, Travis SP, Murphy MF, Palmer KR. Use of endoscopy for management of acute upper gastrointestinal bleeding in the UK: results of a nationwide audit. Gut. 2010;59(8):1022-1029.
    • (2010) Gut , vol.59 , Issue.8 , pp. 1022-1029
    • Hearnshaw, S.A.1    Logan, R.F.2    Lowe, D.3    Travis, S.P.4    Murphy, M.F.5    Palmer, K.R.6
  • 8
    • 3843104780 scopus 로고    scopus 로고
    • RUGBE Investigators. The Canadian Registry on Nonvariceal Upper Gastrointestinal Bleeding and Endoscopy (RUGBE): Endoscopic hemostasis and proton pump inhibition are associated with improved outcomes in a real-life setting
    • Barkun A, Sabbah S, Enns R, et al. RUGBE Investigators. The Canadian Registry on Nonvariceal Upper Gastrointestinal Bleeding and Endoscopy (RUGBE): endoscopic hemostasis and proton pump inhibition are associated with improved outcomes in a real-life setting. Am J Gastroenterol. 2004;99(7):1238- 1246.
    • (2004) Am J Gastroenterol , vol.99 , Issue.7 , pp. 1238-1246
    • Barkun, A.1    Sabbah, S.2    Enns, R.3
  • 9
    • 80052599858 scopus 로고    scopus 로고
    • Acute upper gastrointestinal bleeding in the UK: Patient characteristics, diagnoses and outcomes in the 2007 UK audit
    • Hearnshaw SA, Logan RF, Lowe D, Travis SP, Murphy MF, Palmer KR. Acute upper gastrointestinal bleeding in the UK: patient characteristics, diagnoses and outcomes in the 2007 UK audit. Gut. 2011;60(10):1327-1335.
    • (2011) Gut , vol.60 , Issue.10 , pp. 1327-1335
    • Hearnshaw, S.A.1    Logan, R.F.2    Lowe, D.3    Travis, S.P.4    Murphy, M.F.5    Palmer, K.R.6
  • 10
    • 33748316476 scopus 로고    scopus 로고
    • Review article: Gastrointestinal bleeding with low-dose aspirin - What's the risk?
    • DOI 10.1111/j.1365-2036.2006.03077.x
    • Laine L. Review article: gastrointestinal bleeding with low-dose aspirin-what's the risk? Aliment Pharmacol Ther. 2006;24(6):897-908. (Pubitemid 44326371)
    • (2006) Alimentary Pharmacology and Therapeutics , vol.24 , Issue.6 , pp. 897-908
    • Laine, L.1
  • 11
    • 0347416911 scopus 로고    scopus 로고
    • Risk of Bleeding Complications with Antiplatelet Agents: Meta-Analysis of 338,191 Patients Enrolled in 50 Randomized Controlled Trials
    • DOI 10.1002/ajh.10451
    • Serebruany VL, Malinin AI, Eisert RM, Sane DC. Risk of bleeding complications with antiplatelet agents: meta-analysis of 338 191 patients enrolled in 50 randomized controlled trials. Am J Hematol. 2004;75(1):40-47. (Pubitemid 38040166)
    • (2004) American Journal of Hematology , vol.75 , Issue.1 , pp. 40-47
    • Serebruany, V.L.1    Malinin, A.I.2    Eisert, R.M.3    Sane, D.C.4
  • 12
    • 33749681586 scopus 로고    scopus 로고
    • Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: Population based casecontrol study
    • Hallas J, Dall M, Andries A, et al. Use of single and combined antithrombotic therapy and risk of serious upper gastrointestinal bleeding: population based casecontrol study. BMJ. 2006;333(7571):726.
    • (2006) BMJ , vol.333 , Issue.7571 , pp. 726
    • Hallas, J.1    Dall, M.2    Andries, A.3
  • 13
    • 79955641250 scopus 로고    scopus 로고
    • Long-term use of aspirin and the risk of gastrointestinal bleeding
    • Huang ES, Strate LL, Ho WW, Lee SS, Chan AT. Long-term use of aspirin and the risk of gastrointestinal bleeding. Am J Med. 2011;124(5):426-433.
    • (2011) Am J Med , vol.124 , Issue.5 , pp. 426-433
    • Huang, E.S.1    Strate, L.L.2    Ho, W.W.3    Lee, S.S.4    Chan, A.T.5
  • 15
    • 72249105523 scopus 로고    scopus 로고
    • Reducing the gastrointestinal risks of low-dose aspirin
    • Cryer B. Reducing the gastrointestinal risks of low-dose aspirin. Gastroenterology. 2010;138(1):30-33.
    • (2010) Gastroenterology , vol.138 , Issue.1 , pp. 30-33
    • Cryer, B.1
  • 17
    • 77956899158 scopus 로고    scopus 로고
    • Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillation
    • Hansen ML, Sørensen R, Clausen MT, et al. Risk of bleeding with single, dual, or triple therapy with warfarin, aspirin, and clopidogrel in patients with atrial fibrillation. Arch Intern Med. 2010;170(16):1433-1441.
    • (2010) Arch Intern Med , vol.170 , Issue.16 , pp. 1433-1441
    • Hansen, M.L.1    Sørensen, R.2    Clausen, M.T.3
  • 19
    • 54049118496 scopus 로고    scopus 로고
    • ACCF/ACG/ AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: A report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents
    • American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents
    • Bhatt DL, Scheiman J, Abraham NS, et al. American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. ACCF/ACG/ AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use: a report of the American College of Cardiology Foundation Task Force on Clinical Expert Consensus Documents. J Am Coll Cardiol. 2008;52(18):1502-1517.
    • (2008) J Am Coll Cardiol , vol.52 , Issue.18 , pp. 1502-1517
    • Bhatt, D.L.1    Scheiman, J.2    Abraham, N.S.3
  • 20
    • 79953043171 scopus 로고    scopus 로고
    • Risk of upper gastrointestinal bleeding with low-dose acetylsalicylic acid alone and in combination with clopidogrel and other medications
    • García Rodríguez LA, Lin KJ, Hernández-Díaz S, Johansson S. Risk of upper gastrointestinal bleeding with low-dose acetylsalicylic acid alone and in combination with clopidogrel and other medications. Circulation. 2011;123(10):1108- 1115.
    • (2011) Circulation , vol.123 , Issue.10 , pp. 1108-1115
    • García Rodríguez, L.A.1    Lin, K.J.2    Hernández-Díaz, S.3    Johansson, S.4
  • 21
    • 79960256684 scopus 로고    scopus 로고
    • Cost-effectiveness analysis: Cardiovascular benefits of proton pump inhibitor co-therapy in patients using aspirin for secondary prevention
    • Saini SD, Fendrick AM, Scheiman JM. Cost-effectiveness analysis: cardiovascular benefits of proton pump inhibitor co-therapy in patients using aspirin for secondary prevention. Aliment Pharmacol Ther. 2011;34(2):243-251.
    • (2011) Aliment Pharmacol Ther , vol.34 , Issue.2 , pp. 243-251
    • Saini, S.D.1    Fendrick, A.M.2    Scheiman, J.M.3
  • 22
    • 0030590746 scopus 로고    scopus 로고
    • A randomised, blinded, trial of clopidogrel vs aspirin in patients at risk of ischaemic events (CAPRIE)
    • CAPRIE Steering Committee
    • CAPRIE Steering Committee. A randomised, blinded, trial of clopidogrel vs aspirin in patients at risk of ischaemic events (CAPRIE). Lancet. 1996;348(9038): 1329-1339.
    • (1996) Lancet , vol.348 , Issue.9038 , pp. 1329-1339
  • 23
    • 77953806506 scopus 로고    scopus 로고
    • CHARISMA Investigators. Bleeding complications with dual antiplatelet therapy among patients with stable vascular disease or risk factors for vascular disease: Results from the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial
    • Berger PB, Bhatt DL, Fuster V, et al. CHARISMA Investigators. Bleeding complications with dual antiplatelet therapy among patients with stable vascular disease or risk factors for vascular disease: results from the Clopidogrel for High Atherothrombotic Risk and Ischemic Stabilization, Management, and Avoidance (CHARISMA) trial. Circulation. 2010;121(23):2575-2583.
    • (2010) Circulation , vol.121 , Issue.23 , pp. 2575-2583
    • Berger, P.B.1    Bhatt, D.L.2    Fuster, V.3
  • 24
    • 34548314463 scopus 로고    scopus 로고
    • Drug-drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding
    • DOI 10.1503/cmaj.070186
    • Delaney JA, Opatrny L, Brophy JM, Suissa S. Drug drug interactions between antithrombotic medications and the risk of gastrointestinal bleeding. CMAJ. 2007; 177(4):347-351. (Pubitemid 47339530)
    • (2007) Canadian Medical Association Journal , vol.177 , Issue.4 , pp. 347-351
    • Delaney, J.A.1    Opatrny, L.2    Brophy, J.M.3    Suissa, S.4
  • 25
    • 33847328353 scopus 로고    scopus 로고
    • Effect of antisecretory drugs and nitrates on the risk of ulcer bleeding associated with nonsteroidal anti-inflammatory drugs, antiplatelet agents, and anticoagulants
    • Investigators of the Asociación Española de Gastroenterología
    • Lanas A, García-Rodríguez LA, Arroyo MT, et al. Investigators of the Asociación Española de Gastroenterologí a. Effect of antisecretory drugs and nitrates on the risk of ulcer bleeding associated with nonsteroidal anti-inflammatory drugs, antiplatelet agents, and anticoagulants. Am J Gastroenterol. 2007;102(3):507- 515.
    • (2007) Am J Gastroenterol , vol.102 , Issue.3 , pp. 507-515
    • Lanas, A.1    García-Rodríguez, L.A.2    Arroyo, M.T.3
  • 26
    • 63749112292 scopus 로고    scopus 로고
    • Combination antiplatelet therapy for secondary stroke prevention: Enhanced efficacy or double trouble?
    • Usman MH, Notaro LA, Nagarakanti R, et al. Combination antiplatelet therapy for secondary stroke prevention: enhanced efficacy or double trouble?AmJ Cardiol. 2009;103(8):1107-1112.
    • (2009) AmJ Cardiol , vol.103 , Issue.8 , pp. 1107-1112
    • Usman, M.H.1    Notaro, L.A.2    Nagarakanti, R.3
  • 27
    • 3242770664 scopus 로고    scopus 로고
    • MATCH Investigators. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): Randomised, doubleblind, placebo-controlled trial
    • Diener HC, Bogousslavsky J, Brass LM, et al. MATCH Investigators. Aspirin and clopidogrel compared with clopidogrel alone after recent ischaemic stroke or transient ischaemic attack in high-risk patients (MATCH): randomised, doubleblind, placebo-controlled trial. Lancet. 2004;364(9431):331-337.
    • (2004) Lancet , vol.364 , Issue.9431 , pp. 331-337
    • Diener, H.C.1    Bogousslavsky, J.2    Brass, L.M.3
  • 28
    • 33645861080 scopus 로고    scopus 로고
    • CHARISMA Investigators. Clopidogrel and aspirin vs aspirin alone for the prevention of atherothrombotic events
    • Bhatt DL, Fox KA, Hacke W, et al. CHARISMA Investigators. Clopidogrel and aspirin vs aspirin alone for the prevention of atherothrombotic events. N Engl J Med. 2006;354(16):1706-1717.
    • (2006) N Engl J Med , vol.354 , Issue.16 , pp. 1706-1717
    • Bhatt, D.L.1    Fox, K.A.2    Hacke, W.3
  • 29
    • 33646468354 scopus 로고    scopus 로고
    • Effect of study setting on anticoagulation control: A systematic review and metaregression
    • van Walraven C, Jennings A, Oake N, Fergusson D, Forster AJ. Effect of study setting on anticoagulation control: a systematic review and metaregression. Chest. 2006;129(5):1155-1166.
    • (2006) Chest , vol.129 , Issue.5 , pp. 1155-1166
    • Van Walraven, C.1    Jennings, A.2    Oake, N.3    Fergusson, D.4    Forster, A.J.5
  • 30
    • 44649185707 scopus 로고    scopus 로고
    • Warfarin-induced bleeding complications - clinical presentation and therapeutic options
    • DOI 10.1016/S0049-3848(08)70004-5, PII S0049384808700045
    • Wiedermann CJ, Stockner I. Warfarin-induced bleeding complications- clinical presentation and therapeutic options. Thromb Res. 2008;122(suppl 2): S13-S18. (Pubitemid 351783319)
    • (2008) Thrombosis Research , vol.122 , Issue.SUPPL. 2
    • Wiedermann, C.J.1    Stockner, I.2
  • 31
    • 4644293243 scopus 로고    scopus 로고
    • Hemorrhagic complications of anticoagulant treatment: The Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy
    • DOI 10.1378/chest.126.3-suppl.287S
    • Levine MN, Raskob G, Beyth RJ, Kearon C, Schulman S. Hemorrhagic complications of anticoagulant treatment: the Seventh ACCP Conference on Antithrombotic and Thrombolytic Therapy. Chest. 2004;126(3)(suppl):287S-310S. (Pubitemid 39297958)
    • (2004) Chest , vol.126 , Issue.3 SUPPL.
    • Levine, M.N.1    Raskob, G.2    Beyth, R.J.3    Kearon, C.4    Schulman, S.5
  • 33
    • 70349306707 scopus 로고    scopus 로고
    • Dabigatran vs warfarin in patients with atrial fibrillation
    • RE-LY Steering Committee and Investigators
    • Connolly SJ, Ezekowitz MD, Yusuf S, et al. RE-LY Steering Committee and Investigators. Dabigatran vs warfarin in patients with atrial fibrillation. N Engl J Med. 2009;361(12):1139-1151.
    • (2009) N Engl J Med , vol.361 , Issue.12 , pp. 1139-1151
    • Connolly, S.J.1    Ezekowitz, M.D.2    Yusuf, S.3
  • 34
    • 79952445042 scopus 로고    scopus 로고
    • 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (update on dabigatran): A report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines
    • Wann LS, Curtis AB, Ellenbogen KA, et al. 2011 ACCF/AHA/HRS focused update on the management of patients with atrial fibrillation (update on dabigatran): a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2011;57 (11):1330-1337.
    • (2011) J Am Coll Cardiol , vol.57 , Issue.11 , pp. 1330-1337
    • Wann, L.S.1    Curtis, A.B.2    Ellenbogen, K.A.3
  • 35
    • 65649145705 scopus 로고    scopus 로고
    • ACTIVE Investigators. Effect of clopidogrel added to aspirin in patients with atrial fibrillation
    • Connolly SJ, Pogue J, Hart RG, et al. ACTIVE Investigators. Effect of clopidogrel added to aspirin in patients with atrial fibrillation. N Engl J Med. 2009; 360(20):2066-2078.
    • (2009) N Engl J Med , vol.360 , Issue.20 , pp. 2066-2078
    • Connolly, S.J.1    Pogue, J.2    Hart, R.G.3
  • 36
    • 79551589662 scopus 로고    scopus 로고
    • Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation
    • Freeman JV, Zhu RP, Owens DK, et al. Cost-effectiveness of dabigatran compared with warfarin for stroke prevention in atrial fibrillation. Ann Intern Med. 2011; 154(1):1-11.
    • (2011) Ann Intern Med , vol.154 , Issue.1 , pp. 1-11
    • Freeman, J.V.1    Zhu, R.P.2    Owens, D.K.3
  • 38
    • 18044377421 scopus 로고    scopus 로고
    • Low-close aspirin for secondary cardiovascular prevention - Cardiovascular risks after its perioperative withdrawal versus bleeding risks with its continuation - Review and meta-analysis
    • DOI 10.1111/j.1365-2796.2005.01477.x
    • Burger W, Chemnitius JM, Kneissl GD, Rücker G. Low-dose aspirin for secondary cardiovascular prevention-cardiovascular risks after its perioperative withdrawal vs bleeding risks with its continuation-review and meta-analysis. J Intern Med. 2005;257(5):399-414. (Pubitemid 40604544)
    • (2005) Journal of Internal Medicine , vol.257 , Issue.5 , pp. 399-414
    • Burger, W.1    Chemnitius, J.-M.2    Kneissl, G.D.3    Rucker, G.4
  • 39
    • 74849120868 scopus 로고    scopus 로고
    • Continuation of low-dose aspirin therapy in peptic ulcer bleeding: A randomized trial
    • Sung JJ, Lau JY, Ching JY, et al. Continuation of low-dose aspirin therapy in peptic ulcer bleeding: a randomized trial. Ann Intern Med. 2010;152(1):1-9.
    • (2010) Ann Intern Med , vol.152 , Issue.1 , pp. 1-9
    • Sung, J.J.1    Lau, J.Y.2    Ching, J.Y.3
  • 40
    • 74849091358 scopus 로고    scopus 로고
    • Aspirin withdrawal in acute peptic ulcer bleeding: Are we harming patients?
    • Barkun AN, Bardou M. Aspirin withdrawal in acute peptic ulcer bleeding: are we harming patients? Ann Intern Med. 2010;152(1):52-53, W-12.
    • (2010) Ann Intern Med , vol.152 , Issue.1
    • Barkun, A.N.1    Bardou, M.2
  • 41
    • 78649823909 scopus 로고    scopus 로고
    • ACCF/ACG/AHA. ACCF/ACG/ AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: A focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use
    • Abraham NS, Hlatky MA, Antman EM, et al. ACCF/ACG/AHA. ACCF/ACG/ AHA 2010 expert consensus document on the concomitant use of proton pump inhibitors and thienopyridines: a focused update of the ACCF/ACG/AHA 2008 expert consensus document on reducing the gastrointestinal risks of antiplatelet therapy and NSAID use. Am J Gastroenterol. 2010;105(12):2533-2549.
    • (2010) Am J Gastroenterol , vol.105 , Issue.12 , pp. 2533-2549
    • Abraham, N.S.1    Hlatky, M.A.2    Antman, E.M.3
  • 42
    • 33846484956 scopus 로고    scopus 로고
    • Impact of anticoagulation on rebleeding following endoscopic therapy for nonvariceal upper gastrointestinal hemorrhage
    • DOI 10.1111/j.1572-0241.2006.00969.x
    • Wolf AT, Wasan SK, Saltzman JR. Impact of anticoagulation on rebleeding following endoscopic therapy for nonvariceal upper gastrointestinal hemorrhage. Am J Gastroenterol. 2007;102(2):290-296. (Pubitemid 46160542)
    • (2007) American Journal of Gastroenterology , vol.102 , Issue.2 , pp. 290-296
    • Wolf, A.T.1    Wasan, S.K.2    Saltzman, J.R.3
  • 44
    • 0028344714 scopus 로고
    • Acute gastrointestinal haemorrhage in anticoagulated patients: Diagnoses and response to endoscopic treatment
    • Choudari CP, Rajgopal C, Palmer KR. Acute gastrointestinal haemorrhage in anticoagulated patients: diagnoses and response to endoscopic treatment. Gut. 1994;35(4):464-466. (Pubitemid 24131240)
    • (1994) Gut , vol.35 , Issue.4 , pp. 464-466
    • Choudari, C.P.1    Rajgopal, C.2    Palmer, K.R.3
  • 45
    • 67649861111 scopus 로고    scopus 로고
    • Famotidine for the prevention of peptic ulcers and oesophagitis in patients taking low-dose aspirin (FAMOUS): A phase III, randomised, double-blind, placebo-controlled trial
    • Taha AS, McCloskey C, Prasad R, Bezlyak V. Famotidine for the prevention of peptic ulcers and oesophagitis in patients taking low-dose aspirin (FAMOUS): a phase III, randomised, double-blind, placebo-controlled trial. Lancet. 2009; 374(9684):119-125.
    • (2009) Lancet , vol.374 , Issue.9684 , pp. 119-125
    • Taha, A.S.1    McCloskey, C.2    Prasad, R.3    Bezlyak, V.4
  • 46
    • 53149116673 scopus 로고    scopus 로고
    • Efficacy of esomeprazole (20 mg once daily) for reducing the risk of gastroduodenal ulcers associated with continuous use of low-dose aspirin
    • Yeomans N, Lanas A, Labenz J, et al. Efficacy of esomeprazole (20 mg once daily) for reducing the risk of gastroduodenal ulcers associated with continuous use of low-dose aspirin. Am J Gastroenterol. 2008;103(10):2465-2473.
    • (2008) Am J Gastroenterol , vol.103 , Issue.10 , pp. 2465-2473
    • Yeomans, N.1    Lanas, A.2    Labenz, J.3
  • 47
    • 72249102783 scopus 로고    scopus 로고
    • Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions
    • Ng FH, Wong SY, Lam KF, et al. Famotidine is inferior to pantoprazole in preventing recurrence of aspirin-related peptic ulcers or erosions. Gastroenterology. 2010;138(1):82-88.
    • (2010) Gastroenterology , vol.138 , Issue.1 , pp. 82-88
    • Ng, F.H.1    Wong, S.Y.2    Lam, K.F.3
  • 48
    • 72249105864 scopus 로고    scopus 로고
    • A comparison of aspirin and clopidogrel with or without proton pump inhibitors for the secondary prevention of cardiovascular events in patients at high risk for gastrointestinal bleeding
    • Hsiao FY, Tsai YW, Huang WF, et al. A comparison of aspirin and clopidogrel with or without proton pump inhibitors for the secondary prevention of cardiovascular events in patients at high risk for gastrointestinal bleeding. Clin Ther. 2009; 31(9):2038-2047.
    • (2009) Clin Ther , vol.31 , Issue.9 , pp. 2038-2047
    • Hsiao, F.Y.1    Tsai, Y.W.2    Huang, W.F.3
  • 49
    • 0036985907 scopus 로고    scopus 로고
    • Prevention of NSAID-induced gastroduodenal ulcers
    • CD002296
    • Rostom A, Dube C, Wells G, et al. Prevention of NSAID-induced gastroduodenal ulcers. Cochrane Database Syst Rev. 2002;(4):CD002296.
    • (2002) Cochrane Database Syst Rev , Issue.4
    • Rostom, A.1    Dube, C.2    Wells, G.3
  • 51
    • 79952296065 scopus 로고    scopus 로고
    • Esomeprazole with clopidogrel reduces peptic ulcer recurrence, compared with clopidogrel alone, in patients with atherosclerosis
    • Hsu PI, Lai KH, Liu CP. Esomeprazole with clopidogrel reduces peptic ulcer recurrence, compared with clopidogrel alone, in patients with atherosclerosis. Gastroenterology. 2011;140(3):791-798.
    • (2011) Gastroenterology , vol.140 , Issue.3 , pp. 791-798
    • Hsu, P.I.1    Lai, K.H.2    Liu, C.P.3
  • 52
    • 69249219296 scopus 로고    scopus 로고
    • Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy
    • Shuldiner AR, O'Connell JR, Bliden KP, et al. Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy. JAMA. 2009;302(8):849-857.
    • (2009) JAMA , vol.302 , Issue.8 , pp. 849-857
    • Shuldiner, A.R.1    O'Connell, J.R.2    Bliden, K.P.3
  • 53
    • 58749094444 scopus 로고    scopus 로고
    • Cytochrome P-450 polymorphisms and response to clopidogrel
    • Mega JL, Close SL, Wiviott SD, et al. Cytochrome P-450 polymorphisms and response to clopidogrel. N Engl J Med. 2009;360(4):354-362.
    • (2009) N Engl J Med , vol.360 , Issue.4 , pp. 354-362
    • Mega, J.L.1    Close, S.L.2    Wiviott, S.D.3
  • 54
    • 58749090547 scopus 로고    scopus 로고
    • Genetic determinants of response to clopidogrel and cardiovascular events
    • French Registry of Acute STElevation and Non-ST-Elevation Myocardial Infarction Investigators
    • Simon T, Verstuyft C, Mary-Krause M, et al. French Registry of Acute STElevation and Non-ST-Elevation Myocardial Infarction Investigators. Genetic determinants of response to clopidogrel and cardiovascular events. N Engl J Med. 2009;360(4):363-375.
    • (2009) N Engl J Med , vol.360 , Issue.4 , pp. 363-375
    • Simon, T.1    Verstuyft, C.2    Mary-Krause, M.3
  • 55
    • 79951677465 scopus 로고    scopus 로고
    • Clinical events as a function of proton pump inhibitor use, clopidogrel use, and cytochrome P450 2C19 genotype in a large nationwide cohort of acute myocardial infarction: Results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) registry
    • Simon T, Steg PG, Gilard M, et al. Clinical events as a function of proton pump inhibitor use, clopidogrel use, and cytochrome P450 2C19 genotype in a large nationwide cohort of acute myocardial infarction: results from the French Registry of Acute ST-Elevation and Non-ST-Elevation Myocardial Infarction (FAST-MI) registry. Circulation. 2011;123(5):474-482.
    • (2011) Circulation , vol.123 , Issue.5 , pp. 474-482
    • Simon, T.1    Steg, P.G.2    Gilard, M.3
  • 57
    • 45249088224 scopus 로고    scopus 로고
    • The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: A possible mechanism for clopidogrel resistance
    • Kim KA, Park PW, Hong SJ, Park JY. The effect of CYP2C19 polymorphism on the pharmacokinetics and pharmacodynamics of clopidogrel: a possible mechanism for clopidogrel resistance. Clin Pharmacol Ther. 2008;84(2):236-242.
    • (2008) Clin Pharmacol Ther , vol.84 , Issue.2 , pp. 236-242
    • Kim, K.A.1    Park, P.W.2    Hong, S.J.3    Park, J.Y.4
  • 59
    • 70249139788 scopus 로고    scopus 로고
    • Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: An analysis of two randomised trials
    • O'Donoghue ML, Braunwald E, Antman EM, et al. Pharmacodynamic effect and clinical efficacy of clopidogrel and prasugrel with or without a proton-pump inhibitor: an analysis of two randomised trials. Lancet. 2009;374(9694):989- 997.
    • (2009) Lancet , vol.374 , Issue.9694 , pp. 989-997
    • O'Donoghue, M.L.1    Braunwald, E.2    Antman, E.M.3
  • 60
    • 78650958702 scopus 로고    scopus 로고
    • The potential interaction between clopidogrel and proton pump inhibitors: A systematic review
    • Lima JP, Brophy JM. The potential interaction between clopidogrel and proton pump inhibitors: a systematic review. BMC Med. 2010;8(1):81.
    • (2010) BMC Med , vol.8 , Issue.1 , pp. 81
    • Lima, J.P.1    Brophy, J.M.2
  • 61
    • 79952704502 scopus 로고    scopus 로고
    • Meta-analysis: Risk of fractures with acidsuppressing medication
    • Kwok CS, Yeong JK, Loke YK. Meta-analysis: risk of fractures with acidsuppressing medication. Bone. 2011;48(4):768-776.
    • (2011) Bone , vol.48 , Issue.4 , pp. 768-776
    • Kwok, C.S.1    Yeong, J.K.2    Loke, Y.K.3
  • 62
    • 77957669777 scopus 로고    scopus 로고
    • Increased use of acidsuppressing drugs before the occurrence of ischemic events: A potential source of confounding in recent observational studies
    • Blackburn DF, Lamb DA, Mcleod MM, Eurich DT. Increased use of acidsuppressing drugs before the occurrence of ischemic events: a potential source of confounding in recent observational studies. Pharmacotherapy. 2010;30(10): 985-993.
    • (2010) Pharmacotherapy , vol.30 , Issue.10 , pp. 985-993
    • Blackburn, D.F.1    Lamb, D.A.2    Mcleod, M.M.3    Eurich, D.T.4
  • 64
    • 79956336197 scopus 로고    scopus 로고
    • Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: Nationwide propensity score matched study
    • Charlot M, Grove EL, Hansen PR, et al. Proton pump inhibitor use and risk of adverse cardiovascular events in aspirin treated patients with first time myocardial infarction: nationwide propensity score matched study. BMJ. 2011;342:d2690.
    • (2011) BMJ , vol.342
    • Charlot, M.1    Grove, E.L.2    Hansen, P.R.3
  • 65
    • 74249102181 scopus 로고    scopus 로고
    • Do proton pump inhibitors attenuate the effect of aspirin on platelet aggregation? a randomized crossover study
    • Adamopoulos AB, Sakizlis GN, Nasothimiou EG, et al. Do proton pump inhibitors attenuate the effect of aspirin on platelet aggregation? a randomized crossover study. J Cardiovasc Pharmacol. 2009;54(2):163-168.
    • (2009) J Cardiovasc Pharmacol , vol.54 , Issue.2 , pp. 163-168
    • Adamopoulos, A.B.1    Sakizlis, G.N.2    Nasothimiou, E.G.3
  • 66
    • 77957347819 scopus 로고    scopus 로고
    • Conflicting evidence: What's a clinician to do?
    • de Aquino Lima JP, Brophy JM. Conflicting evidence: what's a clinician to do? Ann Intern Med. 2010;153(6):413-415.
    • (2010) Ann Intern Med , vol.153 , Issue.6 , pp. 413-415
    • De Aquino Lima, J.P.1    Brophy, J.M.2
  • 67
    • 79953849739 scopus 로고    scopus 로고
    • Systematic review of the epidemiology of complicated peptic ulcer disease: Incidence, recurrence, risk factors and mortality
    • Lau JY, Sung J, Hill C, Henderson C, Howden CW, Metz DC. Systematic review of the epidemiology of complicated peptic ulcer disease: incidence, recurrence, risk factors and mortality. Digestion. 2011;84(2):102-113.
    • (2011) Digestion , vol.84 , Issue.2 , pp. 102-113
    • Lau, J.Y.1    Sung, J.2    Hill, C.3    Henderson, C.4    Howden, C.W.5    Metz, D.C.6
  • 68
    • 0031578238 scopus 로고    scopus 로고
    • Expression of vascular endothelial growth factor at the human gastric ulcer margin and in cultured gastric fibroblasts: A new angiogenic factor for gastric ulcer healing
    • DOI 10.1006/bbrc.1997.5974
    • Takahashi M, Kawabe T, Ogura K, et al. Expression of vascular endothelial growth factor at the human gastric ulcer margin and in cultured gastric fibroblasts: a new angiogenic factor for gastric ulcer healing. Biochem Biophys Res Commun. 1997;234(2):493-498. (Pubitemid 27243932)
    • (1997) Biochemical and Biophysical Research Communications , vol.234 , Issue.2 , pp. 493-498
    • Takahashi, M.1    Kawabe, T.2    Ogura, K.3    Maeda, S.4    Mikami, Y.5    Kaneko, N.6    Terano, A.7    Omata, M.8
  • 69
    • 0019860370 scopus 로고
    • Arachidonic acid metabolites and the gastro-intestinal toxicity of anti-inflammatory agents
    • Whittle BJ. Arachidonic acid metabolites and the gastro-intestinal toxicity of anti-inflammatory agents. Prostaglandins. 1981;21(suppl):113-118. (Pubitemid 11019544)
    • (1981) Prostaglandins , vol.21 , Issue.SUPPL. , pp. 113-118
    • Whittle, B.J.R.1
  • 70
    • 35148859360 scopus 로고    scopus 로고
    • Association between genetic polymorphisms in the cyclooxygenase-1 gene promoter and peptic ulcers in Japan
    • Arisawa T, Tahara T, Shibata T, et al. Association between genetic polymorphisms in the cyclooxygenase-1 gene promoter and peptic ulcers in Japan. Int J Mol Med. 2007;20(3):373-378.
    • (2007) Int J Mol Med , vol.20 , Issue.3 , pp. 373-378
    • Arisawa, T.1    Tahara, T.2    Shibata, T.3
  • 71
    • 77951523654 scopus 로고    scopus 로고
    • Aspirin-induced peptic ulcer and genetic polymorphisms
    • Shiotani A, Sakakibara T, Nomura M, et al. Aspirin-induced peptic ulcer and genetic polymorphisms. J Gastroenterol Hepatol. 2010;25(suppl 1):S31-S34.
    • (2010) J Gastroenterol Hepatol , vol.25 , Issue.SUPPL. 1
    • Shiotani, A.1    Sakakibara, T.2    Nomura, M.3
  • 72
    • 21344459039 scopus 로고    scopus 로고
    • Host TNF-α-1031 and -863 promoter single nucleotide polymorphisms determine the risk of benign ulceration after H pylori infection
    • Lu CC, Sheu BS, Chen TW, et al. Host TNF-α-1031 and -863 promoter single nucleotide polymorphisms determine the risk of benign ulceration after H pylori infection. Am J Gastroenterol. 2005;100(6):1274-1282.
    • (2005) Am J Gastroenterol , vol.100 , Issue.6 , pp. 1274-1282
    • Lu, C.C.1    Sheu, B.S.2    Chen, T.W.3
  • 73
    • 78650343791 scopus 로고    scopus 로고
    • Modification in oxidative stress, inflammation, and lipoprotein assembly in response to hepatocyte nuclear factor 4α knockdown in intestinal epithelial cells
    • Marcil V, Seidman E, Sinnett D, et al. Modification in oxidative stress, inflammation, and lipoprotein assembly in response to hepatocyte nuclear factor 4α knockdown in intestinal epithelial cells. J Biol Chem. 2010;285(52):40448-40460.
    • (2010) J Biol Chem , vol.285 , Issue.52 , pp. 40448-40460
    • Marcil, V.1    Seidman, E.2    Sinnett, D.3
  • 74
    • 79953332012 scopus 로고    scopus 로고
    • Canadian Cardiovascular Society atrial fibrillation guidelines 2010: Prevention of stroke and systemic thromboembolism in atrial fibrillation and flutter
    • CCS Atrial Fibrillation Guidelines Committee
    • Cairns JA, Connolly S, McMurtry S, Stephenson M, Talajic M; CCS Atrial Fibrillation Guidelines Committee. Canadian Cardiovascular Society atrial fibrillation guidelines 2010: prevention of stroke and systemic thromboembolism in atrial fibrillation and flutter. Can J Cardiol. 2011;27(1):74-90.
    • (2011) Can J Cardiol , vol.27 , Issue.1 , pp. 74-90
    • Cairns, J.A.1    Connolly, S.2    McMurtry, S.3    Stephenson, M.4    Talajic, M.5
  • 75
    • 77955012467 scopus 로고    scopus 로고
    • Stroke in paroxysmal atrial fibrillation: Report from the Stockholm Cohort of Atrial Fibrillation
    • Friberg L, Hammar N, Rosenqvist M. Stroke in paroxysmal atrial fibrillation: report from the Stockholm Cohort of Atrial Fibrillation. Eur Heart J. 2010;31 (8):967-975.
    • (2010) Eur Heart J , vol.31 , Issue.8 , pp. 967-975
    • Friberg, L.1    Hammar, N.2    Rosenqvist, M.3
  • 77
    • 76749163232 scopus 로고    scopus 로고
    • Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: The Euro Heart Survey on Atrial Fibrillation
    • Lip GY, Nieuwlaat R, Pisters R, Lane DA, Crijns HJ. Refining clinical risk stratification for predicting stroke and thromboembolism in atrial fibrillation using a novel risk factor-based approach: the Euro Heart Survey on Atrial Fibrillation. Chest. 2010; 137(2):263-272.
    • (2010) Chest , vol.137 , Issue.2 , pp. 263-272
    • Lip, G.Y.1    Nieuwlaat, R.2    Pisters, R.3    Lane, D.A.4    Crijns, H.J.5
  • 78
    • 77955872745 scopus 로고    scopus 로고
    • A novel userfriendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: The Euro Heart Survey
    • Pisters R, Lane DA, Nieuwlaat R, de Vos CB, Crijns HJ, Lip GY. A novel userfriendly score (HAS-BLED) to assess 1-year risk of major bleeding in patients with atrial fibrillation: the Euro Heart Survey. Chest. 2010;138(5):1093-1100.
    • (2010) Chest , vol.138 , Issue.5 , pp. 1093-1100
    • Pisters, R.1    Lane, D.A.2    Nieuwlaat, R.3    De Vos, C.B.4    Crijns, H.J.5    Lip, G.Y.6
  • 79
    • 33749536913 scopus 로고    scopus 로고
    • Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications
    • Hernández-Díaz S, García Rodríguez LA. Cardioprotective aspirin users and their excess risk of upper gastrointestinal complications. BMC Med. 2006; 4:22.
    • (2006) BMC Med , vol.4 , pp. 22
    • Hernández-Díaz, S.1    García Rodríguez, L.A.2


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