Novel pathogenic mechanism and therapeutic approaches to angioedema associated with C1 inhibitor deficiency

Journal of Allergy and Clinical Immunology

Volumn 124, Issue 6, 2009, Pages

  Bossi, Fleur ^a   Fischetti, Fabio ^a   Regoli, Domenico ^b   Durigutto, Paolo ^a   Frossi, Barbara ^c   Gobeil Jr , Fernand ^d   Ghebrehiwet, Berhane ^e   Peerschke, Ellinor I ^f   Cicardi, Marco ^g   Tedesco, Francesco ^a  

^a UNIVERSITY OF TRIESTE   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

^c UNIVERSITY OF UDINE   (Italy)

^d UNIVERSITÉ DE SHERBROOKE   (Canada)

^e STONY BROOK UNIVERSITY   (United States)

^f MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^g UNIVERSITY OF MILAN   (Italy)

Author keywords

Angioedema; B1R; B2R; bradykinin; C1 inhibitor; complement; endothelial cells; gC1QR; leakage assay; vascular leakage

Indexed keywords

ALBUMIN; BRADYKININ; BRADYKININ B1 RECEPTOR; BRADYKININ B1 RECEPTOR ANTAGONIST; BRADYKININ DERIVATIVE; BREFELDIN A; COMPLEMENT COMPONENT C1Q; COMPLEMENT COMPONENT C1S INHIBITOR; COMPLEMENT RECEPTOR; HIGH MOLECULAR WEIGHT KININOGEN; ICATIBANT; INTERLEUKIN 1BETA; R 954; UNCLASSIFIED DRUG;

ANGIONEUROTIC EDEMA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; C1 INHIBITOR DFICIENCY; COMPLEMENT DEFICIENCY; CONTROLLED STUDY; DISEASE ASSOCIATION; DRUG EFFECT; ENDOTHELIUM CELL; HUMAN; HUMAN CELL; MALE; NONHUMAN; PATHOGENESIS; PLASMA; PRIORITY JOURNAL; RAT;

EID: 71249105731     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jaci.2009.08.007     Document Type: Article

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