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Volumn 879, Issue 31, 2011, Pages 3728-3734
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Chlorpromazine quantification in human plasma by UPLC-electrospray ionization tandem mass spectrometry. Application to a comparative pharmacokinetic study
a,b
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Author keywords
Bioavailability; Chlorpromazine; Pharmacokinetics; UPLC MS MS
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Indexed keywords
ANALYTES;
ANALYTICAL METHOD;
BIOAVAILABILITY;
CHLORPROMAZINE;
CROSSOVER DESIGN;
DIETHYL ETHERS;
ELECTROSPRAYS;
FOOD AND DRUG ADMINISTRATION;
HUMAN PLASMAS;
INTER-ASSAY PRECISION;
INTERNAL STANDARDS;
INTRA-ASSAY PRECISION;
LINEAR CALIBRATION CURVE;
LIQUID-LIQUID EXTRACTION;
MOBILE PHASE;
PHARMACOKINETIC STUDIES;
PLASMA SAMPLES;
POSITIVE MODE;
RELATIVE BIOAVAILABILITY;
TANDEM MASS SPECTROMETRY;
TRIPLE-QUADRUPOLE MASS SPECTROMETER;
ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;
UPLC-MS/MS;
ACETONITRILE;
BIOCHEMISTRY;
FORMIC ACID;
LIQUID CHROMATOGRAPHY;
LIQUIDS;
MASS SPECTROMETRY;
PHARMACOKINETICS;
PLASMA (HUMAN);
PLASMAS;
SOLVENT EXTRACTION;
ELECTROSPRAY IONIZATION;
CHLORPROMAZINE;
DICHLOROMETHANE;
ETHER;
ADULT;
ARTICLE;
COMPARATIVE STUDY;
CROSSOVER PROCEDURE;
DRUG BIOAVAILABILITY;
ELECTROSPRAY MASS SPECTROMETRY;
HUMAN;
HUMAN EXPERIMENT;
LIQUID LIQUID EXTRACTION;
NORMAL HUMAN;
PLASMA;
PRIORITY JOURNAL;
RANDOMIZED CONTROLLED TRIAL;
SINGLE DRUG DOSE;
ULTRA PERFORMANCE LIQUID CHROMATOGRAPHY;
ADOLESCENT;
ADULT;
AMITRIPTYLINE;
AREA UNDER CURVE;
BIOLOGICAL AVAILABILITY;
CHLORPROMAZINE;
CHROMATOGRAPHY, HIGH PRESSURE LIQUID;
CROSS-OVER STUDIES;
DRUG STABILITY;
FEMALE;
HUMANS;
LIMIT OF DETECTION;
LINEAR MODELS;
MALE;
MIDDLE AGED;
RANDOM ALLOCATION;
REPRODUCIBILITY OF RESULTS;
SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;
TANDEM MASS SPECTROMETRY;
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EID: 82955222324
PISSN: 15700232
EISSN: 1873376X
Source Type: Journal
DOI: 10.1016/j.jchromb.2011.10.020 Document Type: Article |
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Times cited : (19)
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References (28)
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