A modified and highly useful protocol for the Brønsted acid catalyzed, enantioselective, vinylogous Mannich reaction with aliphatic aldimines

Synthesis

Volumn , Issue 24, 2011, Pages 4050-4058

  Abels, Falko ^a   Schneider, Christoph ^a  

^a UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

BINOL; contact ion pair; dienolate; organocatalyis; phosphoric acid; vinylogous Mannich reaction

Indexed keywords

BINOL; CONTACT ION PAIR; DIENOLATE; ORGANOCATALYIS; VINYLOGOUS MANNICH REACTION;

ENANTIOSELECTIVITY; PHOSPHORIC ACID;

CHEMICAL REACTIONS;

1 (4 METHOXYPHENYL) 2 PROPYLPIPERIDINE; 1 (4 METHOXYPHENYL) 6 PROPYLPIPERIDIN 2 ONE; ACETAL DERIVATIVE; ALDEHYDE DERIVATIVE; ALIPHATIC ALDIMINE DERIVATIVE; BRONSTED ACID; CONIINE HYDROCHLORIDE; DIETHYL 5 (4 METHOXYPHENYLAMINO)OCT 2 ENEDIOATE; ETHYL 10 CHLORO 5 (4 METHOXYPHENYLAMINO)DEC 2 ENOATE; ETHYL 5 (4 METHOXYPHENYLAMINO) 4 METHYLHEPT 2 ENOATE; ETHYL 5 (4 METHOXYPHENYLAMINO) 4,7 DIMETHYLOCT 2 ENOATE; ETHYL 5 (4 METHOXYPHENYLAMINO) 6 METHYLEPT 2 ENOATE; ETHYL 5 (4 METHOXYPHENYLAMINO) 7 METHYLOC 2 ENOATE; ETHYL 5 (4 METHOXYPHENYLAMINO)DODEC 2 ENOATE; ETHYL 5 (4 METHOXYPHENYLAMINO)HEPT 2 ENOATE; ETHYL 5 (4 METHOXYPHENYLAMINO)OCT 2 ENOATE; ETHYL 5 (4 METHOXYPHENYLAMINO)OCTANOATE; ETHYL 5 (4 METHOXYPHENYLAMINO)PENTADEC 2 EN 14 YNOATE; ETHYL 5 (4 METHOXYPHENYLAMINO)TETRADEC 2 ENOATE; ETHYL 5 CYCLOHEXYL 5 (4 METHOXYPHENYLAMINO)PENT 2 ENOATE; O,O SILYLKETENE ACETAL DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYSIS; CHEMICAL STRUCTURE; ENANTIOSELECTIVITY; MANNICH REACTION; STEREOCHEMISTRY; VINYLOGOUS MANNICH REACTION;

EID: 82955203220     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0031-1289303     Document Type: Article

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