Enteral tube feeding alters the oral indigenous microbiota in elderly adults

Applied and Environmental Microbiology

Volumn 77, Issue 19, 2011, Pages 6739-6745

  Takeshita, Toru ^a   Yasui, Masaki ^a   Tomioka, Mikiko ^a   Nakano, Yoshio ^b   Shimazaki, Yoshihiro ^a   Yamashita, Yoshihisa ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b NIHON UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

16S RRNA GENE; BACTERIAL GENUS; CORYNEBACTERIUM; ENTERAL FEEDING; MICROBIOTAS; MULTIVARIATE ANALYSIS OF VARIANCES; PERMANOVA; PYROSEQUENCING; STREPTOCOCCUS AGALACTIAE; STRIATUM; TERMINAL RESTRICTION FRAGMENT LENGTH POLYMORPHISMS;

FEEDING; GENES; MULTIVARIANT ANALYSIS; RNA;

TUBES (COMPONENTS);

BACTERIAL DNA; RIBOSOME DNA; RNA 16S;

ADULT; BACTERIUM; ELDERLY POPULATION; FEEDING; MICROORGANISM; ORAL HEALTH; PATHOGEN; PUBLIC HEALTH;

ADULT; AGED; ARTICLE; BACTERIUM; BIODIVERSITY; CHEMISTRY; CLASSIFICATION; CLUSTER ANALYSIS; DNA SEQUENCE; ENTERIC FEEDING; GENETICS; HUMAN; ISOLATION AND PURIFICATION; MICROBIOLOGY; PHYLOGENY; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; TONGUE;

ADULT; AGED; BACTERIA; BIODIVERSITY; CLUSTER ANALYSIS; DNA, BACTERIAL; DNA, RIBOSOMAL; ENTERAL NUTRITION; HUMANS; PHYLOGENY; POLYMORPHISM, RESTRICTION FRAGMENT LENGTH; RNA, RIBOSOMAL, 16S; SEQUENCE ANALYSIS, DNA; TONGUE;

EID: 82955202642     PISSN: 00992240     EISSN: 10985336     Source Type: Journal    
DOI: 10.1128/AEM.00651-11     Document Type: Article

References (36)

1. Abuksis, G., et al. 2000. Percutaneous endoscopic gastrostomy: high mortality rates in hospitalized patients. Am. J. Gastroenterol. 95:128-132.
2. Bartlett, J. G. 1987. Anaerobic bacterial infections of the lung. Chest 91: 901-909.
3. Bartlett, J. G. 2005. The role of anaerobic bacteria in lung abscess. Clin. Infect. Dis. 40:923-925.
4. Caporaso, J. G., et al. 2010. PyNAST: a flexible tool for aligning sequences to a template alignment. Bioinformatics 26:266-267.
5. Cole, J. R., et al. 2009. The Ribosomal Database Project: improved alignments and new tools for rRNA analysis. Nucleic Acids Res. 37:D141-D145.
6. Costello, E. K., et al. 2009. Bacterial community variation in human body habitats across space and time. Science 326:1694-1697.
7. Dahlen, G. 2009. Bacterial infections of the oral mucosa. Periodontol. 2000 49:13-38.
8. DeSantis, T. Z., et al. 2006. Greengenes, a chimera-checked 16S rRNA gene database and workbench compatible with ARB. Appl. Environ. Microbiol. 72:5069-5072.
9. Dewhirst, F. E., et al. 2010. The human oral microbiome. J. Bacteriol. 192:5002-5017.
10. Edwards, M. S., and C. J. Baker. 2005. Group B streptococcal infections in elderly adults. Clin. Infect. Dis. 41:839-847.
11. El-Solh, A. A., et al. 2003. Microbiology of severe aspiration pneumonia in institutionalized elderly. Am. J. Respir. Crit. Care Med. 167:1650-1654.
12. Finucane, T. E., and J. P. Bynum. 1996. Use of tube feeding to prevent aspiration pneumonia. Lancet 348:1421-1424.
13. Haas, B. J., et al. 2011. Chimeric 16S rRNA sequence formation and detection in Sanger and 454-pyrosequenced PCR amplicons. Genome Res. 21: 494-504.
14. Hamady, M., C. Lozupone, and R. Knight. 2010. Fast UniFrac: facilitating high-throughput phylogenetic analyses of microbial communities including analysis of pyrosequencing and PhyloChip data. ISME J. 4:17-27.
15. Janssens, J. P., and K. H. Krause. 2004. Pneumonia in the very old. Lancet Infect. Dis. 4:112-124.
16. Kuo, S., R. L. Rhodes, S. L. Mitchell, V. Mor, and J. M. Teno. 2009. Natural history of feeding-tube use in nursing home residents with advanced dementia. J. Am. Med. Dir. Assoc. 10:264-270.
17. Leibovitz, A., G. Plotnikov, B. Habot, M. Rosenberg, and R. Segal. 2003. Pathogenic colonization of oral flora in frail elderly patients fed by nasogastric tube or percutaneous enterogastric tube. J. Gerontol. A Biol. Sci. Med. Sci. 58:52-55.
18. Leibovitz, A., et al. 2003. Saliva secretion and oral flora in prolonged nasogastric tube-fed elderly patients. Isr. Med. Assoc. J. 5:329-332.
19. Ling, Z., et al. 2010. Molecular analysis of the diversity of vaginal microbiota associated with bacterial vaginosis. BMC Genomics 11:488.
20. Lozupone, C., and R. Knight. 2005. UniFrac: a new phylogenetic method for comparing microbial communities. Appl. Environ. Microbiol. 71:8228-8235.
21. Marik, P. E., and D. Kaplan. 2003. Aspiration pneumonia and dysphagia in the elderly. Chest 124:328-336.
22. Mitchell, S. L., J. M. Teno, J. Roy, G. Kabumoto, and V. Mor. 2003. Clinical and organizational factors associated with feeding tube use among nursing home residents with advanced cognitive impairment. JAMA 290:73-80.
23. Murphy, L. M., and T. O. Lipman. 2003. Percutaneous endoscopic gastrostomy does not prolong survival in patients with dementia. Arch. Intern. Med. 163:1351-1353.
24. Otsuka, Y., et al. 2006. Emergence of multidrug-resistant Corynebacterium striatum as a nosocomial pathogen in long-term hospitalized patients with underlying diseases. Diagn. Microbiol. Infect. Dis. 54:109-114.
25. Price, M. N., P. S. Dehal, and A. P. Arkin. 2009. FastTree: computing large minimum evolution trees with profiles instead of a distance matrix. Mol. Biol. Evol. 26:1641-1650.
26. R Development Core Team. 2007. R: a language and environment for statistical computing. R Foundation for Statistical Computing, Vienna, Austria.
27. Renom, F., et al. 2007. Nosocomial outbreak of Corynebacterium striatum infection in patients with chronic obstructive pulmonary disease. J. Clin. Microbiol. 45:2064-2067.
28. Rothan-Tondeur, M., et al. 2003. Risk factors for nosocomial pneumonia in a geriatric hospital: a control-case one-center study. J. Am. Geriatr. Soc. 51:997-1001.
29. Sartor, R. B. 2008. Therapeutic correction of bacterial dysbiosis discovered by molecular techniques. Proc. Natl. Acad. Sci. U. S. A. 105:16413-16414.
30. Tada, A., N. Hanada, and H. Tanzawa. 2002. The relation between tube feeding and Pseudomonas aeruginosa detection in the oral cavity. J. Gerontol. A Biol. Sci. Med. Sci. 57:M71-M72.
31. Takeshita, T., et al. 2010. Microfloral characterization of the tongue coating and associated risk for pneumonia-related health problems in institutionalized older adults. J. Am. Geriatr. Soc. 58:1050-1057.
32. Tamboli, C. P., C. Neut, P. Desreumaux, and J. F. Colombel. 2004. Dysbiosis in inflammatory bowel disease. Gut 53:1-4.
33. Terpenning, M., and K. Shay. 2002. Oral health is cost-effective to maintain but costly to ignore. J. Am. Geriatr. Soc. 50:584-585.
34. Tsai, T. H., J. S. Jerng, K. Y. Chen, C. J. Yu, and P. C. Yang. 2005. Community-acquired thoracic empyema in older people. J. Am. Geriatr. Soc. 53:1203-1209.
35. van Vliet, M. J., H. J. Harmsen, E. S. de Bont, and W. J. Tissing. 2010. The role of intestinal microbiota in the development and severity of chemotherapy-induced mucositis. PLoS Pathog. 6:e1000879.
36. Yoneyama, T., et al. 2002. Oral care reduces pneumonia in older patients in nursing homes. J. Am. Geriatr. Soc. 50:430-433.