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Volumn 94, Issue 3, 2011, Pages 434-441

Circulating leptin and insulin in obese patients with and without type 2 diabetes mellitus: Relation to ghrelin and oxidative stress

Author keywords

Ghrelin; Leptin; Obesity; Oxidative stress; Type 2 diabetes mellitus

Indexed keywords

GHRELIN; GLUCOSE; INSULIN; LEPTIN; LIPID PEROXIDE; NITRIC OXIDE;

EID: 82955186986     PISSN: 01688227     EISSN: 18728227     Source Type: Journal    
DOI: 10.1016/j.diabres.2011.08.023     Document Type: Article
Times cited : (38)

References (48)
  • 1
    • 73749083481 scopus 로고    scopus 로고
    • Global estimates of the prevalence of diabetes for 2010 and 2030
    • Shaw J.E., Sicree R.A., Zimmet P.Z. Global estimates of the prevalence of diabetes for 2010 and 2030. Diabetes Res Clin Pract 2010, 87:4-14.
    • (2010) Diabetes Res Clin Pract , vol.87 , pp. 4-14
    • Shaw, J.E.1    Sicree, R.A.2    Zimmet, P.Z.3
  • 2
    • 72449186547 scopus 로고    scopus 로고
    • The role of gut hormones in the regulation of body weight and energy homeostasis
    • Karra E., Batterham R.L. The role of gut hormones in the regulation of body weight and energy homeostasis. Mol Cell Endocrinol 2010, 316(2):120-128.
    • (2010) Mol Cell Endocrinol , vol.316 , Issue.2 , pp. 120-128
    • Karra, E.1    Batterham, R.L.2
  • 3
    • 33845405222 scopus 로고    scopus 로고
    • Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy
    • Kahn S.E., Haffner S.M., Heise M.A., Herman W.H., Holman R.R., Jones N.P., et al. Glycemic durability of rosiglitazone, metformin, or glyburide monotherapy. N Engl J Med 2006, 355(23):2427-2443.
    • (2006) N Engl J Med , vol.355 , Issue.23 , pp. 2427-2443
    • Kahn, S.E.1    Haffner, S.M.2    Heise, M.A.3    Herman, W.H.4    Holman, R.R.5    Jones, N.P.6
  • 4
    • 0036157858 scopus 로고    scopus 로고
    • Ghrelin and leptin pulse discharge in fed and fasted rats
    • Bagnasco M., Kalra P.S., Kalra S.P. Ghrelin and leptin pulse discharge in fed and fasted rats. Endocrinology 2002, 143:726-729.
    • (2002) Endocrinology , vol.143 , pp. 726-729
    • Bagnasco, M.1    Kalra, P.S.2    Kalra, S.P.3
  • 5
    • 33748664379 scopus 로고    scopus 로고
    • Drug insight: the functions of ghrelin and its potential as a multitherapeutic hormone
    • Kojima M., Kangawa K. Drug insight: the functions of ghrelin and its potential as a multitherapeutic hormone. Nat Clin Pract Endocrinol Metab 2006, 2:80-88.
    • (2006) Nat Clin Pract Endocrinol Metab , vol.2 , pp. 80-88
    • Kojima, M.1    Kangawa, K.2
  • 6
    • 0036720528 scopus 로고    scopus 로고
    • Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin
    • Ariyasu H., Takaya K., Hosoda H., Iwakura H., Ebihara K., Mori K., et al. Delayed short-term secretory regulation of ghrelin in obese animals: evidenced by a specific RIA for the active form of ghrelin. Endocrinology 2002, 143:3341-3350.
    • (2002) Endocrinology , vol.143 , pp. 3341-3350
    • Ariyasu, H.1    Takaya, K.2    Hosoda, H.3    Iwakura, H.4    Ebihara, K.5    Mori, K.6
  • 8
    • 0033711116 scopus 로고    scopus 로고
    • The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion
    • Wren A.M., Small C.J., Ward H.L., Murphy K.G., Dakin C.L., Taheri S., et al. The novel hypothalamic peptide ghrelin stimulates food intake and growth hormone secretion. Endocrinology 2002, 141:4325-4328.
    • (2002) Endocrinology , vol.141 , pp. 4325-4328
    • Wren, A.M.1    Small, C.J.2    Ward, H.L.3    Murphy, K.G.4    Dakin, C.L.5    Taheri, S.6
  • 9
    • 0035940390 scopus 로고    scopus 로고
    • Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: relationships between ghrelin and anabolic/catabolic factors
    • Nagaya N., Uematsu M., Kojima M., Date Y., Nakazato M., Okumura H., et al. Elevated circulating level of ghrelin in cachexia associated with chronic heart failure: relationships between ghrelin and anabolic/catabolic factors. Circulation 2001, 104:2034-2038.
    • (2001) Circulation , vol.104 , pp. 2034-2038
    • Nagaya, N.1    Uematsu, M.2    Kojima, M.3    Date, Y.4    Nakazato, M.5    Okumura, H.6
  • 11
    • 0037243646 scopus 로고    scopus 로고
    • Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women
    • Tolle V., Kadem M., Bluet-Pajot M.T., Frere D., Foulon C., Bossu C., et al. Balance in ghrelin and leptin plasma levels in anorexia nervosa patients and constitutionally thin women. J Clin Endocrinol Metab 2003, 88:109-116.
    • (2003) J Clin Endocrinol Metab , vol.88 , pp. 109-116
    • Tolle, V.1    Kadem, M.2    Bluet-Pajot, M.T.3    Frere, D.4    Foulon, C.5    Bossu, C.6
  • 12
    • 0036097362 scopus 로고    scopus 로고
    • Ghrelin is present in pancreatic β-cells of humans and rats and stimulates insulin secretion
    • Date Y., Nakazato M., Hashiguchi S., Dezaki K., Mondal M.S., Hosoda H., et al. Ghrelin is present in pancreatic β-cells of humans and rats and stimulates insulin secretion. Diabetes 2002, 51:124-129.
    • (2002) Diabetes , vol.51 , pp. 124-129
    • Date, Y.1    Nakazato, M.2    Hashiguchi, S.3    Dezaki, K.4    Mondal, M.S.5    Hosoda, H.6
  • 13
    • 33747077266 scopus 로고    scopus 로고
    • Plasma leptin and its relationship with lipid peroxidation and nitric oxide in obese female patients with or without hypertension
    • Konukoglu D., Serin O., Turhan M.S. Plasma leptin and its relationship with lipid peroxidation and nitric oxide in obese female patients with or without hypertension. Arch Med Res 2006, 37:602-606.
    • (2006) Arch Med Res , vol.37 , pp. 602-606
    • Konukoglu, D.1    Serin, O.2    Turhan, M.S.3
  • 15
    • 0037085391 scopus 로고    scopus 로고
    • Ghrelin modulates the downstream molecules of insulin signaling in hepatoma cells
    • Murata M., Okimura Y., Iida K., Matsumoto M., Sowa H., Kaji H., et al. Ghrelin modulates the downstream molecules of insulin signaling in hepatoma cells. J Biol Chem 2002, 277:5667-5674.
    • (2002) J Biol Chem , vol.277 , pp. 5667-5674
    • Murata, M.1    Okimura, Y.2    Iida, K.3    Matsumoto, M.4    Sowa, H.5    Kaji, H.6
  • 16
    • 34247098895 scopus 로고    scopus 로고
    • Ghrelin, the peripheral hunger hormone
    • Higgins S.C., Gueorguiev M., Korbonits M. Ghrelin, the peripheral hunger hormone. Ann Med 2007, 39:116-136.
    • (2007) Ann Med , vol.39 , pp. 116-136
    • Higgins, S.C.1    Gueorguiev, M.2    Korbonits, M.3
  • 17
    • 17844403548 scopus 로고    scopus 로고
    • Differential association of basal and postprandial plasma ghrelin with leptin, insulin, and type 2 diabetes
    • Erdmann J., Lippl F., Wagenpfeil S., Schusdziarra V. Differential association of basal and postprandial plasma ghrelin with leptin, insulin, and type 2 diabetes. Diabetes 2005, 54:1371-1378.
    • (2005) Diabetes , vol.54 , pp. 1371-1378
    • Erdmann, J.1    Lippl, F.2    Wagenpfeil, S.3    Schusdziarra, V.4
  • 18
    • 0038583808 scopus 로고    scopus 로고
    • Leptin levels in type 2 diabetes: associations with measures of insulin resistance and insulin secretion
    • Wauters M., Considine R.V., Yudkin J.S., Peiffer F., De Leeuw I., Van Gaal L.F. Leptin levels in type 2 diabetes: associations with measures of insulin resistance and insulin secretion. Horm Metab Res 2003, 35:92-96.
    • (2003) Horm Metab Res , vol.35 , pp. 92-96
    • Wauters, M.1    Considine, R.V.2    Yudkin, J.S.3    Peiffer, F.4    De Leeuw, I.5    Van Gaal, L.F.6
  • 19
    • 21444454887 scopus 로고    scopus 로고
    • Molecular targets of diabetic cardiovascular complications
    • Ahmad F.K., Zhiheng H., King G.L. Molecular targets of diabetic cardiovascular complications. Curr Drug Targets 2005, 6:487-494.
    • (2005) Curr Drug Targets , vol.6 , pp. 487-494
    • Ahmad, F.K.1    Zhiheng, H.2    King, G.L.3
  • 20
    • 77953509678 scopus 로고    scopus 로고
    • Adipose tissue, inflammation and atherosclerosis
    • Gustafson B. Adipose tissue, inflammation and atherosclerosis. J Atheroscler Thromb 2010, 17:332-341.
    • (2010) J Atheroscler Thromb , vol.17 , pp. 332-341
    • Gustafson, B.1
  • 21
    • 0037164747 scopus 로고    scopus 로고
    • Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT
    • Baldanzi G., Filigheddu N., Cutrupi S., Catapano F., Bonissoni S., Fubini A., et al. Ghrelin and des-acyl ghrelin inhibit cell death in cardiomyocytes and endothelial cells through ERK1/2 and PI 3-kinase/AKT. J Cell Biol 2002, 159:1029-1039.
    • (2002) J Cell Biol , vol.159 , pp. 1029-1039
    • Baldanzi, G.1    Filigheddu, N.2    Cutrupi, S.3    Catapano, F.4    Bonissoni, S.5    Fubini, A.6
  • 22
    • 0033795281 scopus 로고    scopus 로고
    • Lipid hydroperoxide determination in dark chicken meat through a ferrous oxidation-xylenol orange method
    • Grau A., Codony R., Rafecas M., Barroeta A.C., Guardiola F. Lipid hydroperoxide determination in dark chicken meat through a ferrous oxidation-xylenol orange method. J Agric Food Chem 2000, 48(9):4136-4143.
    • (2000) J Agric Food Chem , vol.48 , Issue.9 , pp. 4136-4143
    • Grau, A.1    Codony, R.2    Rafecas, M.3    Barroeta, A.C.4    Guardiola, F.5
  • 23
    • 0023706894 scopus 로고
    • Release of reactive nitrogen intermediate from mouse peritoneal macrophage comparison of activating cytokines and evidence for independent production
    • Ding A.H., Nathan C.F., Stuchr D.J. Release of reactive nitrogen intermediate from mouse peritoneal macrophage comparison of activating cytokines and evidence for independent production. J Immunol 1988, 141(7):2407-2412.
    • (1988) J Immunol , vol.141 , Issue.7 , pp. 2407-2412
    • Ding, A.H.1    Nathan, C.F.2    Stuchr, D.J.3
  • 24
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and b-cell function from fasting plasma glucose and insulin concentrations in man
    • Matthews D.R., Hosker J.P., Rudenski A.S., Naylor B.A., Treacher D.F., Turner R.C. Homeostasis model assessment: insulin resistance and b-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 1985, 28:412-419.
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 25
    • 0021995003 scopus 로고
    • Increased plasma levels of immunoreactive beta-endorphin and corticotropin in non-insulin-dependent diabetes
    • Vermes I., Steinmetz E., Schoorl J., van der Veen E.A., Tilders F.J. Increased plasma levels of immunoreactive beta-endorphin and corticotropin in non-insulin-dependent diabetes. Lancet 1985, 2(8457):725-726.
    • (1985) Lancet , vol.2 , Issue.8457 , pp. 725-726
    • Vermes, I.1    Steinmetz, E.2    Schoorl, J.3    van der Veen, E.A.4    Tilders, F.J.5
  • 27
    • 0037220691 scopus 로고    scopus 로고
    • Plasma ghrelin concentrations are not regulated by glucose or insulin: a double-blind, placebo-controlled crossover clamp study
    • Schaller G., Schmidt A., Pleiner J., Woloszczuk W., Wolzt M., Luger A. Plasma ghrelin concentrations are not regulated by glucose or insulin: a double-blind, placebo-controlled crossover clamp study. Diabetes 2003, 52:16-20.
    • (2003) Diabetes , vol.52 , pp. 16-20
    • Schaller, G.1    Schmidt, A.2    Pleiner, J.3    Woloszczuk, W.4    Wolzt, M.5    Luger, A.6
  • 28
    • 1842735215 scopus 로고    scopus 로고
    • Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach
    • Lippl F., Kircher F., Erdmann J., Allescher H.D., Schusdziarra V. Effect of GIP, GLP-1, insulin and gastrin on ghrelin release in the isolated rat stomach. Regul Pept 2004, 119:93-98.
    • (2004) Regul Pept , vol.119 , pp. 93-98
    • Lippl, F.1    Kircher, F.2    Erdmann, J.3    Allescher, H.D.4    Schusdziarra, V.5
  • 30
    • 4344675633 scopus 로고    scopus 로고
    • Leptin modulates orexigenic effects of ghrelin and attenuates adiponectin and insulin levels and selectively the dark-phase feeding as revealed by central leptin gene therapy
    • Ueno H., Dube M.G., Inui A., Kalra P.S., Kalra S.P. Leptin modulates orexigenic effects of ghrelin and attenuates adiponectin and insulin levels and selectively the dark-phase feeding as revealed by central leptin gene therapy. Endocrinology 2004, 145:4176-4184.
    • (2004) Endocrinology , vol.145 , pp. 4176-4184
    • Ueno, H.1    Dube, M.G.2    Inui, A.3    Kalra, P.S.4    Kalra, S.P.5
  • 31
    • 0037509943 scopus 로고    scopus 로고
    • Hyperleptinemia prevents increased plasma ghrelin concentration during shortterm moderate caloric restriction in rats
    • Barazzoni R., Zanetti M., Stebel M., Biolo G., Cattin L., Guarnieri G. Hyperleptinemia prevents increased plasma ghrelin concentration during shortterm moderate caloric restriction in rats. Gastroenterology 2003, 124:1188-1192.
    • (2003) Gastroenterology , vol.124 , pp. 1188-1192
    • Barazzoni, R.1    Zanetti, M.2    Stebel, M.3    Biolo, G.4    Cattin, L.5    Guarnieri, G.6
  • 33
    • 0842269756 scopus 로고    scopus 로고
    • Ghrelin levels are not regulated by recombinant leptin administration and/or three days of fasting in healthy subjects
    • Chan J.L., Bullen J., Lee J.H., Yiannakouris N., Mantzoros C.S. Ghrelin levels are not regulated by recombinant leptin administration and/or three days of fasting in healthy subjects. J Clin Endocrinol Metab 2004, 89:335-343.
    • (2004) J Clin Endocrinol Metab , vol.89 , pp. 335-343
    • Chan, J.L.1    Bullen, J.2    Lee, J.H.3    Yiannakouris, N.4    Mantzoros, C.S.5
  • 35
    • 44949195830 scopus 로고    scopus 로고
    • Centrally located body fat is related to appetitive hormones in healthy postmenopausal women
    • Ritland L.M., Alekel D.L., Matvienko O.A., Hanson K.B., Stewart J.W., Hanson L.N., et al. Centrally located body fat is related to appetitive hormones in healthy postmenopausal women. Eur J Endocrinol 2008, 158(6):889-897.
    • (2008) Eur J Endocrinol , vol.158 , Issue.6 , pp. 889-897
    • Ritland, L.M.1    Alekel, D.L.2    Matvienko, O.A.3    Hanson, K.B.4    Stewart, J.W.5    Hanson, L.N.6
  • 36
    • 82955205347 scopus 로고    scopus 로고
    • Impacting obesity and glycemic control using a culturally-sensitive diabetes education program in Hispanic patients with type 2 diabetes
    • Peterson R.M., Beeson L., Shulz E., Firek A., De Leon M., Balcazar H., et al. Impacting obesity and glycemic control using a culturally-sensitive diabetes education program in Hispanic patients with type 2 diabetes. Int J Body Compos Res 2010, 8(3):85-94.
    • (2010) Int J Body Compos Res , vol.8 , Issue.3 , pp. 85-94
    • Peterson, R.M.1    Beeson, L.2    Shulz, E.3    Firek, A.4    De Leon, M.5    Balcazar, H.6
  • 38
    • 4644301777 scopus 로고    scopus 로고
    • Ghrelin - update on a novel hormonal system
    • Korbonits M., Grossman A.B. Ghrelin - update on a novel hormonal system. Eur J Endocrinol 2004, 151(Suppl. 1):S67-S70.
    • (2004) Eur J Endocrinol , vol.151 , Issue.SUPPL. 1
    • Korbonits, M.1    Grossman, A.B.2
  • 39
    • 68349150756 scopus 로고    scopus 로고
    • CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
    • Nishimura S., Manabe I., Nagasaki M., Eto K., Yamashita H., Ohsugi M., et al. CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity. Nat Med 2009, 15:914-920.
    • (2009) Nat Med , vol.15 , pp. 914-920
    • Nishimura, S.1    Manabe, I.2    Nagasaki, M.3    Eto, K.4    Yamashita, H.5    Ohsugi, M.6
  • 41
    • 0034871316 scopus 로고    scopus 로고
    • Leptin concentrations in the United States: relations with demographic and anthropometric measures
    • Ruhl C.E., Everhart J.E. Leptin concentrations in the United States: relations with demographic and anthropometric measures. Am J Clin Nutr 2001, 74:295-301.
    • (2001) Am J Clin Nutr , vol.74 , pp. 295-301
    • Ruhl, C.E.1    Everhart, J.E.2
  • 42
    • 4544256147 scopus 로고    scopus 로고
    • Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling
    • Shi H., Tzameli I., Bjørbaek C., Flier J.S. Suppressor of cytokine signaling 3 is a physiological regulator of adipocyte insulin signaling. J Biol Chem 2004, 279:34733-34740.
    • (2004) J Biol Chem , vol.279 , pp. 34733-34740
    • Shi, H.1    Tzameli, I.2    Bjørbaek, C.3    Flier, J.S.4
  • 44
    • 55549100240 scopus 로고    scopus 로고
    • Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome
    • Gomes V.A., Casella-Filho A., Chagas A.C., Tanus-Santos J.E. Enhanced concentrations of relevant markers of nitric oxide formation after exercise training in patients with metabolic syndrome. Nitric Oxide 2008, 19:345-350.
    • (2008) Nitric Oxide , vol.19 , pp. 345-350
    • Gomes, V.A.1    Casella-Filho, A.2    Chagas, A.C.3    Tanus-Santos, J.E.4
  • 45
    • 0025289049 scopus 로고
    • Free radical antioxidant enzymes and carcinogenesis
    • Sun Y. Free radical antioxidant enzymes and carcinogenesis. Free Radic Biol Med 1990, 8:583-599.
    • (1990) Free Radic Biol Med , vol.8 , pp. 583-599
    • Sun, Y.1
  • 46
    • 0030114516 scopus 로고    scopus 로고
    • Photocarcinogenesis: mechanisms, models and human health implications
    • Mukhtar H., Elmets C.A. Photocarcinogenesis: mechanisms, models and human health implications. Photochem Photobiol 1996, 63:355-447.
    • (1996) Photochem Photobiol , vol.63 , pp. 355-447
    • Mukhtar, H.1    Elmets, C.A.2
  • 47
    • 12944299790 scopus 로고    scopus 로고
    • A protective effect of adinopectin against oxidative stress in Japanese Americans: the association between adinopectin or leptin and urinary isoprostane
    • Nakanishi S., Yamane K., Kamei N., Hideki N., Okubo M., Kohno N. A protective effect of adinopectin against oxidative stress in Japanese Americans: the association between adinopectin or leptin and urinary isoprostane. Metabolism 2005, 54:194-199.
    • (2005) Metabolism , vol.54 , pp. 194-199
    • Nakanishi, S.1    Yamane, K.2    Kamei, N.3    Hideki, N.4    Okubo, M.5    Kohno, N.6
  • 48
    • 0032999682 scopus 로고    scopus 로고
    • Leptin induces oxidative stress in human endothelial cells
    • Bouloumi{dotless}e A., Marumo T., Lafontan M., Busse R. Leptin induces oxidative stress in human endothelial cells. FASEB J 1999, 13:1231-1238.
    • (1999) FASEB J , vol.13 , pp. 1231-1238
    • Bouloumie, A.1    Marumo, T.2    Lafontan, M.3    Busse, R.4


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