Identification of Inhibitors of the Leishmania cdc2-Related Protein Kinase CRK3

ChemMedChem

Volumn 6, Issue 12, 2011, Pages 2214-2224

  Cleghorn, Laura A T ^a   Woodland, Andrew ^a   Collie, Iain T ^a   Torrie, Leah S ^a   Norcross, Neil ^a   Luksch, Torsten ^a   Mpamhanga, Chido ^a   Walker, Roderick G ^b   Mottram, Jeremy C ^b   Brenk, Ruth ^a   Frearson, Julie A ^a   Gilbert, Ian H ^a   Wyatt, Paul G ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b UNIVERSITY OF GLASGOW   (United Kingdom)

Author keywords

CRK3; Cyclin dependent cdc2 related kinases; Leishmaniasis; Triazolopyridines; Ureas

Indexed keywords

CYCLIN DEPENDENT KINASE 2 INHIBITOR; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE CRK3 INHIBITOR; UNCLASSIFIED DRUG;

ARTICLE; DRUG IDENTIFICATION; DRUG POTENCY; FOLLOW UP; LEISHMANIA; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

BINDING SITES; CDC2 PROTEIN KINASE; COMPUTER SIMULATION; DRUG EVALUATION, PRECLINICAL; HUMANS; LEISHMANIA; LEISHMANIASIS; PROTEIN KINASE INHIBITORS; PROTEIN STRUCTURE, TERTIARY; PROTOZOAN PROTEINS; PYRAZOLES; PYRIMIDINES; STRUCTURE-ACTIVITY RELATIONSHIP; UREA;

EID: 82955186879     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100344     Document Type: Article

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