Induction of prolonged, continuous slow-wave sleep by blocking cerebral H 1 histamine receptors in rats

British Journal of Pharmacology

Volumn 165, Issue 1, 2012, Pages 167-182

  Ikeda Sagara, Masami ^a   Ozaki, Tomoya ^a   Shahid, Mohammad ^a   Morioka, Eri ^a   Wada, Kazuma ^a   Honda, Kazuki ^b   Hori, Ayana ^c   Matsuya, Yuji ^c   Toyooka, Naoki ^a,c   Ikeda, Masayuki ^a  

^a UNIVERSITY OF TOYAMA   (Japan)

^b Hamri Co Ltd   (Japan)

^c UNIVERSITY OF TOYAMA   (Japan)

Author keywords

continuous micro infusion; intracellular calcium; preoptic sleep centres; second generation antihistamines; sleep encephalogram; third ventricle; yellow cameleon

Indexed keywords

CALCIUM ION; CETIRIZINE; CHLORPHENIRAMINE; HISTAMINE H1 RECEPTOR;

ADULT ANIMAL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTINUOUS INFUSION; CONTROLLED STUDY; DROWSINESS; DRUG ACTIVITY; DRUG DISTRIBUTION; DRUG DOSE COMPARISON; DRUG EFFECT; DRUG MECHANISM; MALE; NERVE CELL; NONHUMAN; NONREM SLEEP; PREOPTIC AREA; PRIORITY JOURNAL; RAT; REM SLEEP; SLOW WAVE SLEEP; WAKEFULNESS;

ANIMALS; CALCIUM; CETIRIZINE; CHLORPHENIRAMINE; FLUORESCENT DYES; HELA CELLS; HISTAMINE H1 ANTAGONISTS; HUMANS; MALE; MOLECULAR STRUCTURE; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, HISTAMINE H1; SLEEP; STAINING AND LABELING;

EID: 82955176989     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/j.1476-5381.2011.01547.x     Document Type: Article

References (66)

1. Adam K, Oswald I, (1986). The hypnotic effects of antihistamine: promethazine. Br J Clin Pharmacol 22: 715-717.
2. Alexander SPH, Mathie A, Peters JA, (2011). Guide to Receptors and Channels (GRAC), 5th edition. Br J Pharmacol 164: S1-S324.
3. Bassano JL, Caille EJ, (1979). Effects of two antihistaminic compounds (mequitazine, dexchlorpheniramine) on sleep. Sleep distortion by antihistaminics. Waking Sleeping 3: 57-61. (Pubitemid 9251186)
4. Bergman J, (1990). Psychomotor stimulant effects of the stereoisomers of chlorpheniramine. Psychopharmacology (Berl) 100: 132-134. (Pubitemid 20015685)
5. 1-receptors in guinea-pig central nervous system established by autoradiography with [125I] iodobolpyramine. Neuroscience 26: 553-600.
6. Boyle J, Eriksson M, Stanley N, Fujita T, Kumagi Y, (2006). Allergy medication in Japanese volunteers: treatment effect of single doses on nocturnal sleep architecture and next day residual effects. Curr Med Res Opin 22: 1343-1351. (Pubitemid 44085586)
7. 1-receptor antagonists in HL-60 cells, basophils, and mast cells. Biochem Pharmacol 51: 125-131. (Pubitemid 26020687)
8. Chou TC, Bjorkum AA, Gaus SE, Lu J, Scammell TE, Saper CB, (2002). Afferents to the ventrolateral preoptic nucleus. J Neurosci 22: 977-990. (Pubitemid 34141777)
9. Chu M, Huang ZL, Qu WM, Eguchi N, Yao MH, Urade Y, (2004). Extracellular histamine level in the frontal cortex is positively correlated with the amount of wakefulness in rats. Neurosci Res 49: 417-420. (Pubitemid 38953859)
10. Crochet S, Sakai K, (1999). Effects of microdialysis application of monoamines on the EEG and behavioural states in the cat mesopontine tegmentum. Eur J Neurosci 11: 3738-3752. (Pubitemid 29484269)
11. Crochet S, Onoe H, Sakai K, (2006). A potent non-monoaminergic paradoxical sleep inhibitory system: a reverse microdialysis and single-unit recording study. Eur J Neurosci 24: 1404-1412. (Pubitemid 44401663)
12. 1 receptor antagonist: lack of sedative potential on the EEG in the rodent. Neuropsychobiology 32: 214-221.
13. Gallopin T, Fort P, Eggermann E, Cauli B, Luppi PH, Rossier J, et al,. (2000). Identification of sleep-promoting neurons in vitro. Nature 40: 992-995. (Pubitemid 30243592)
14. 194. Mol Pharmacol 61: 391-399. (Pubitemid 34112814)
15. Gong H, Szymusiak R, King J, Steininger T, McGinty D, (2000). Sleep-related c-Fos protein expression in the preoptic hypothalamus: effects of ambient warming. Am J Physiol 279: R2079-R2088.
16. Gong H, McGinty D, Guzman-Marin R, Chew KT, Stewart D, Szymusiak R, (2004). Activation of c-fos in GABAergic neurones in the preoptic area during sleep and in response to sleep deprivation. J Physiol 556: 935-946. (Pubitemid 38660324)
17. Gupta A, Chatelain P, Massingham R, Jonsson EN, Hammarlund-Udenaes M, (2006). Brain distribution of cetirizine enantiomers: comparison of three different tissue-to-plasma partition coefficients: K(p), K(p,u), and K(p,uu). Drug Metab Dispos 34: 318-323. (Pubitemid 43145034)
18. Huang ZL, Qu WM, Li WD, Mochizuki T, Eguchi N, Watanabe T, et al,. (2001). Arousal effect of orexin A depends on activation of the histaminergic system. Proc Natl Acad Sci U S A 98: 9965-9970. (Pubitemid 32769411)
19. 1 receptor knockout mice. Proc Natl Acad Sci U S A 103: 4687-4692.
20. Huang ZL, Urade Y, Hayaishi O, (2007). Prostaglandins and adenosine in the regulation of sleep and wakefulness. Curr Opin Pharmacol 7: 33-38. (Pubitemid 46238038)
21. Ikeda M, Honda K, Inoué S, (1995). Circadian time-dependent modulation of sleep and brain temperature (Tbr) by methylcobalamine and resultant prolongation of Tbr freerunning period in rats. Biol Rhythm Res 26: 521-531.
22. Ikeda M, Sagara M, Sekino Y, Shirao T, Honda K, Yoshioka T, et al,. (2001). The sulphydryl reagent, N-ethylmaleimide, disrupts sleep and blocks A1 adenosine receptor-mediated inhibition of intracellular calcium signaling in the in vitro ventromedial preoptic nucleus. Neuroscience 106: 733-743. (Pubitemid 33000178)
23. 2+ in single suprachiasmatic nucleus neurons. Neuron 38: 253-263. (Pubitemid 36555651)
24. Ikeda M, Ikeda-Sagara M, Okada T, Clement P, Urade Y, Nagai T, et al,. (2005). Brain oxidation is an initial process in sleep induction. Neuroscience 130: 1029-1040. (Pubitemid 40094633)
25. Inagaki N, Yamatodani A, Ando-Yamamoto M, Tohyama M, Watanabe T, Wada H, (1988). Organization of histaminergic fibers in the rat brain. J Comp Neurol 273: 283-300.
26. Inoué S, (1993). Sleep-promoting substance (SPS) and physiological sleep regulation. Zool Sci 10: 557-576.
27. Jewett RE, (1968). Effects of promethazine on sleep stages in the cat. Exp Neurol 21: 368-382.
28. 1A receptors. Behav Brain Res 148: 199-208. (Pubitemid 37543668)
29. Khateb A, Serafin M, Mühlethaler M, (1990). Histamine excites pedunculopontine neurones in guinea pig brainstem slices. Neurosci Lett 112: 257-262.
30. Khateb A, Fort P, Pegna A, Jones BE, Mühlethaler M, (1995). Cholinergic nucleus basalis neurons are excited by histamine in vitro. Neuroscience 69: 495-506.
31. Kubo N, Shirakawa O, Kuno T, Tanaka C, (1987). Antimuscarinic effects of antihistamines: quantitative evaluation by receptor-binding assay. Jpn J Pharmacol 43: 277-282. (Pubitemid 17034958)
32. Lin JS, Sakai K, Jouvet M, (1988). Evidence for histaminergic arousal mechanisms in the hypothalamus of cat. Neuropharmacology 27: 111-122. (Pubitemid 18052351)
33. Lin JS, Sakai K, Jouvet M, (1994). Hypothalamo-preoptic histaminergic projections in sleep-wake control in the cat. Eur J Neurosci 6: 618-625. (Pubitemid 24106846)
34. Lin JS, Hou Y, Sakai K, Jouvet M, (1996). Histaminergic descending inputs to the mesopontine tegmentum and their role in the control of cortical activation and wakefulness in the cat. J Neurosci 16: 1523-1537. (Pubitemid 26145931)
35. Lu J, Sherman D, Devor M, Saper CB, (2006). A putative flip-flop switch for control of REM sleep. Nature 441: 589-594. (Pubitemid 43927285)
36. Lundius EG, Sanchez-Alavez M, Ghochani Y, Klaus J, Tabarean IV, (2010). Histamine influences body temperature by acting at H1 and H3 receptors on distinct populations of preoptic neurons. J Neurosci 30: 4369-4381.
37. Mahar Doan KM, Wring SA, Shampine LJ, Jordan KH, Bishop JP, Kratz J, et al,. (2004). Steady-state brain concentrations of antihistamines in rats: interplay of membrane permeability, P-glycoprotein efflux and plasma protein binding. Pharmacology 72: 92-98. (Pubitemid 39179257)
38. Marzanatti M, Monopoli A, Trampus M, Ongini E, (1989). Effects of nonsedating histamine H1-antagonists on EEG activity and behavior in the cat. Pharmacol Biochem Behav 32: 861-866. (Pubitemid 19210267)
39. McCormick DA, (1992). Neurotransmitter actions in the thalamus and cerebral cortex. J Clin Neurophysiol 9: 212-223.
40. Mochizuki T, Yamatodani A, Okakura K, Horii A, Inagaki N, Wada H, (1992). Circadian rhythm of histamine release from the hypothalamus of freely moving rats. Physiol Behav 51: 391-394.
41. 2-histamine receptor agonists and antagonists on sleep and wakefulness in the rat. J Neural Transm 66: 1-11. (Pubitemid 16011942)
42. Nicholson AN, (1983). Antihistamines and sedation. Lancet 2: 211-213.
43. 2 antagonists. Neuropharmacology 24: 245-250. (Pubitemid 15051593)
44. 2 receptors agonists and antagonists after intraventricular infusion in fowls. Res Commun Chem Pathol Pharmacol 27: 431-450. (Pubitemid 10131622)
45. Onodera K, Yamatodani A, Watanabe T, Wada H, (1994). Neuropharmacology of the histaminergic neuron system in the brain and its relationship with behavioral disorders. Prog Neurobiol 42: 685-702. (Pubitemid 24199522)
46. 1 receptor antagonists in two functional models. Eur J Pharmacol 506: 257-264. (Pubitemid 41071398)
47. Parmentier R, Ohtsu H, Djebbara-Hannas Z, Valatx JL, Watanabe T, Lin JS, (2002). Anatomical, physiological, and pharmacological characteristics of histidine decarboxylase knock-out mice: evidence for the role of brain histamine in behavioral and sleep-wake control. J Neurosci 22: 7695-7711. (Pubitemid 35386369)
48. Prast H, Dietl H, Philippu A, (1992). Pulsatile release of histamine in the hypothalamus of conscious rats. J Auton Nerv Syst 9: 105-110.
49. Ramesh V, Thakkar MM, Strecker RE, Basheer R, McCarley RW, (2004). Wakefulness-inducing effects of histamine in the basal forebrain of freely moving rats. Behav Brain Res 152: 271-278. (Pubitemid 38757898)
50. 1 receptor activation reduces a background leakage potassium current. Neuroscience 59: 579-588. (Pubitemid 24131513)
51. Reuse JJ, (1948). Comparison of various histamine antagonists. Br J Pharmacol Chemother 3: 174-180.
52. Risberg AM, Risberg J, Ingvar DH, (1975). Effects of promethazine on nocturnal sleep in normal men. Psychopharmacology 43: 279-284.
53. 1-antagonists. Biol Pharm Bull 22: 1079-1082. (Pubitemid 29507947)
54. 1 antagonists block M-currents in dissociated rat cortical neurons. Brain Res 1057: 81-87. (Pubitemid 41338090)
55. Seidel WF, Cohen S, Bliwise NG, Roth T, Dement WC, (1987). Cetirizine effects on objective measures of daytime sleepiness and performance. Ann Allergy 59: 58-62. (Pubitemid 18026406)
56. Sherin JE, Shiromani PJ, McCarley RW, Saper CB, (1996). Activation of ventrolateral preoptic neurons during sleep. Science 271: 216-219.
57. Sherrod TR, Loew ER, Schloemer HF, (1947). Pharmacological properties of antihistamine drugs, benadryl, pyribenzamine, and neoantergan. J Pharmacol Exp Ther 89: 247-255.
58. Slater JW, Zechnich AD, Haxby DG, (1999). Second-generation antihistamines: a comparative review. Drugs 57: 31-47.
59. Sunshine A, Zighelboim I, Laska E, (1978). Hypnotic activity of diphenhydramine, methapyrilene, and placebo. J Clin Pharmacol 18: 425-431. (Pubitemid 9003313)
60. Taglialatela M, Timmerman H, Annunziato L, (2000). Cardiotoxic potential and CNS effects of first-generation antihistamines. Trends Pharmacol Sci 21: 52-56. (Pubitemid 30100339)
61. Takahashi K, Lin JS, Sakai K, (2009). Characterization and mapping of sleep-waking specific neurons in the basal forebrain and preoptic hypothalamus in mice. Neuroscience 161: 269-292.
62. Tanda G, Kopajtic TA, Katz JL, (2008). Cocaine-like neurochemical effects of antihistaminic medications. J Neurochem 106: 147-157. (Pubitemid 351840210)
63. 1-antagonists on the sleep-wake cycle in sleep-disturbed rats. J Pharmacol Sci 103: 201-206. (Pubitemid 46294652)
64. Tsai CL, Matsumura K, Nakayama T, Itowi N, Yamatodani A, Wada H, (1989). Effects of histamine on thermosensitive neurons in rat preoptic slice preparations. Neurosci Lett 102: 297-302. (Pubitemid 19179807)
65. Wauquier A, Van den Broeck WA, Awouters F, Janssen PA, (1981). A comparison between astemizole and other antihistamines on sleep-wakefulness cycles in dogs. Neuropharmacology 20: 853-859. (Pubitemid 11061213)
66. White JM, Rumbold GR, (1988). Behavioural effects of histamine and its antagonists: a review. Psychopharmacology (Berl) 95: 1-14.