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Volumn 8, Issue 6, 2011, Pages 2142-2150

Functional characterization of apical transporters expressed in rat proximal tubular cells (PTCs) in primary culture

Author keywords

ABC transporter; kidney; proximal tubules; renal reabsorption; SLC transporter

Indexed keywords

ALPHA METHYLGLUCOSIDE; CARNITINE; CARRIER PROTEIN; CEFALEXIN; GLYCYLSARCOSINE; PEPTIDE TRANSPORTER 1; PEPTIDE TRANSPORTER 2; PROTEIN; PROTEIN OCTN1; PROTEIN OCTN2; SODIUM GLUCOSE COTRANSPORTER 1; SODIUM GLUCOSE COTRANSPORTER 2; THIONEINE; UNCLASSIFIED DRUG;

EID: 82955169678     PISSN: 15438384     EISSN: 15438392     Source Type: Journal    
DOI: 10.1021/mp200096r     Document Type: Article
Times cited : (17)

References (38)
  • 1
    • 42049122112 scopus 로고    scopus 로고
    • Apical Transporters for Neutral Amino Acids: Physiology and Pathophysiology
    • Broer, S. Apical Transporters for Neutral Amino Acids: Physiology and Pathophysiology Physiology 2008, 23, 95-103
    • (2008) Physiology , vol.23 , pp. 95-103
    • Broer, S.1
  • 2
    • 25644448895 scopus 로고    scopus 로고
    • Role and relevance of peptide transporter 2 (PEPT2) in the kidney and choroid plexus: In vivo studies with glycylsarcosine in wild-type and PEPT2 knockout mice
    • DOI 10.1124/jpet.105.089359
    • Ocheltree, S. M.; Shen, H.; Hu, Y.; Keep, R. F.; Smith, D. E. Role and Relevance of Peptide Transporter 2 (Pept2) in the Kidney and Choroid Plexus: In Vivo Studies with Glycylsarcosine in Wild-Type and Pept2 Knockout Mice J. Pharmacol. Exp. Ther. 2005, 315, 240-247 (Pubitemid 41380517)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.315 , Issue.1 , pp. 240-247
    • Ocheltree, S.M.1    Shen, H.2    Hu, Y.3    Keep, R.F.4    Smith, D.E.5
  • 3
    • 0032493741 scopus 로고    scopus 로고
    • Molecular and functional identification of sodium ion-dependent, high affinity human carnitine transporter OCTN2
    • DOI 10.1074/jbc.273.32.20378
    • Tamai, I.; Ohashi, R.; Nezu, J.-i.; Yabuuchi, H.; Oku, A.; Shimane, M.; Sai, Y.; Tsuji, A. Molecular and Functional Identification of Sodium Ion-Dependent, High Affinity Human Carnitine Transporter Octn2 J. Biol. Chem. 1998, 273, 20378-20382 (Pubitemid 28377603)
    • (1998) Journal of Biological Chemistry , vol.273 , Issue.32 , pp. 20378-20382
    • Tamai, I.1    Ohashi, R.2    Nezu, J.-I.3    Yabuuchi, H.4    Oku, A.5    Shimane, M.6    Sai, Y.7    Tsujit, A.8
  • 6
    • 33845887252 scopus 로고    scopus 로고
    • Concentration-dependent mode of interaction of angiotensin II receptor blockers with uric acid transporter
    • DOI 10.1124/jpet.106.112755
    • Iwanaga, T.; Sato, M.; Maeda, T.; Ogihara, T.; Tamai, I. Concentration-Dependent Mode of Interaction of Angiotensin II Receptor Blockers with Uric Acid Transporter J. Pharmacol. Exp. Ther. 2007, 320, 211-217 (Pubitemid 46025736)
    • (2007) Journal of Pharmacology and Experimental Therapeutics , vol.320 , Issue.1 , pp. 211-217
    • Iwanaga, T.1    Sato, M.2    Maeda, T.3    Ogihara, T.4    Tamai, I.5
  • 8
    • 0031434178 scopus 로고    scopus 로고
    • Cloning and characterization of a novel human pH-dependent organic cation transporter, OCTN1
    • DOI 10.1016/S0014-5793(97)01441-5, PII S0014579397014415
    • Tamai, I.; Yabuuchi, H.; Nezu, J.; Sai, Y.; Oku, A.; Shimane, M.; Tsuji, A. Cloning and Characterization of a Novel Human ph-Dependent Organic Cation Transporter, Octn1 FEBS Lett. 1997, 419, 107-111 (Pubitemid 28011227)
    • (1997) FEBS Letters , vol.419 , Issue.1 , pp. 107-111
    • Tamai, I.1    Yabuuchi, H.2    Nezu, J.-I.3    Sai, Y.4    Oku, A.5    Shimane, M.6    Tsuji, A.7
  • 9
    • 0025355827 scopus 로고
    • In vivo evidence for carrier-mediated uptake of β-lactam antibiotics through organic anion transport systems in rat kidney and liver
    • Tsuji, A.; Terasaki, T.; Tamai, I.; Takeda, K. In Vivo Evidence for Carrier-Mediated Uptake of Beta-Lactam Antibiotics through Organic Anion Transport Systems in Rat Kidney and Liver J. Pharmacol. Exp. Ther. 1990, 253, 315-320 (Pubitemid 20141516)
    • (1990) Journal of Pharmacology and Experimental Therapeutics , vol.253 , Issue.1 , pp. 315-320
    • Tsuji, A.1    Terasaki, T.2    Tamai, I.3    Takeda, K.4
  • 11
    • 15744368796 scopus 로고    scopus 로고
    • Physiological, pharmacological and clinical features of the multidrug resistance protein 2
    • DOI 10.1016/j.biopha.2005.01.005
    • Fardel, O.; Jigorel, E.; Le Vee, M.; Payen, L. Physiological, Pharmacological and Clinical Features of the Multidrug Resistance Protein 2 Biomed. Pharmacother. 2005, 59, 104-114 (Pubitemid 40417519)
    • (2005) Biomedicine and Pharmacotherapy , vol.59 , Issue.3 , pp. 104-114
    • Fardel, O.1    Jigorel, E.2    Le Vee, M.3    Payen, L.4
  • 13
    • 0034927304 scopus 로고    scopus 로고
    • P-glycoprotein in HK-2 proximal tubule cell line
    • DOI 10.1081/JDI-100104717
    • Tramonti, G.; Romiti, N.; Norpth, M.; Chieli, E. P-Glycoprotein in HK-2 Proximal Tubule Cell Line Renal Failure 2001, 23, 331-337 (Pubitemid 32692269)
    • (2001) Renal Failure , vol.23 , Issue.3-4 , pp. 331-337
    • Tramonti, G.1    Romiti, N.2    Norpoth, M.3    Chieli, E.4
  • 15
    • 34547169521 scopus 로고    scopus 로고
    • Expression of thirty-six drug transporter genes in human intestine, liver, kidney, and organotypic cell lines
    • DOI 10.1124/dmd.107.014902
    • Hilgendorf, C.; Ahlin, G.; Seithel, A.; Artursson, P.; Ungell, A.-L.; Karlsson, J. Expression of Thirty-Six Drug Transporter Genes in Human Intestine, Liver, Kidney, and Organotypic Cell Lines Drug Metab. Dispos. 2007, 35, 1333-1340 (Pubitemid 47121774)
    • (2007) Drug Metabolism and Disposition , vol.35 , Issue.8 , pp. 1333-1340
    • Hilgendorf, C.1    Ahlin, G.2    Seithel, A.3    Artursson, P.4    Ungell, A.-L.5    Karlsson, J.6
  • 16
    • 33750011601 scopus 로고    scopus 로고
    • Mitochondrial glutathione transport: Physiological, pathological and toxicological implications
    • DOI 10.1016/j.cbi.2006.03.001, PII S0009279706000536
    • Lash, L. H. Mitochondrial Glutathione Transport: Physiological, Pathological and Toxicological Implications Chem.-Biol. Interact. 2006, 163, 54-67 (Pubitemid 44572210)
    • (2006) Chemico-Biological Interactions , vol.163 , Issue.1-2 , pp. 54-67
    • Lash, L.H.1
  • 18
    • 0023892643 scopus 로고
    • Transport of Tetraethylammonium by a Kidney Epithelial Cell Line (LLC-PK1)
    • Fauth, C.; Rossier, B.; Roch-Ramel, F. Transport of Tetraethylammonium by a Kidney Epithelial Cell Line (LLC-PK1) Am. J. Physiol. 1988, 254, F351-F357
    • (1988) Am. J. Physiol. , vol.254
    • Fauth, C.1    Rossier, B.2    Roch-Ramel, F.3
  • 20
    • 0031105408 scopus 로고    scopus 로고
    • Cell lines with extended in vitro growth potential from human renal proximal tubule: Characterization, response to inducers, and comparison with established cell lines
    • Racusen, L. C.; Monteil, C.; Sgrignoli, A.; Lucskay, M.; Marouillat, S.; Rhim, J. G. S.; Morin, J.-p. Cell Lines with Extended in Vitro Growth Potential from Human Renal Proximal Tubule: Characterization, Response to Inducers, and Comparison with Established Cell Lines J. Lab. Clin. Med. 1997, 129, 318-329 (Pubitemid 27169434)
    • (1997) Journal of Laboratory and Clinical Medicine , vol.129 , Issue.3 , pp. 318-329
    • Racusen, L.C.1    Monteil, C.2    Sgrignoli, A.3    Lucskay, M.4    Marouillat, S.5    Rhim, J.G.S.6    Morin, J.-P.7
  • 21
    • 0024455217 scopus 로고
    • Isolation of two distinct populations of cells from rat kidney cortex and their use in the study of chemical-induced toxicity
    • Lash, L. H.; Tokarz, J. Isolation of Two Distinct Populations of Cells from Rat Kidney Cortex and Their Use in the Study of Chemical-Induced Toxicity Anal. Biochem. 1989, 182, 271-279 (Pubitemid 19277103)
    • (1989) Analytical Biochemistry , vol.182 , Issue.2 , pp. 271-279
    • Lash, L.H.1    Tokarz, J.J.2
  • 22
    • 0017184389 scopus 로고
    • A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding
    • Bradford, M. M. A Rapid and Sensitive Method for the Quantitation of Microgram Quantities of Protein Utilizing the Principle of Protein-Dye Binding Anal. Biochem. 1976, 72, 248-54
    • (1976) Anal. Biochem. , vol.72 , pp. 248-54
    • Bradford, M.M.1
  • 23
    • 0028234548 scopus 로고
    • +/Glucose Cotransporter. Re-Evaluation of Function and Distribution of Expression
    • +/Glucose Cotransporter. Re-Evaluation of Function and Distribution of Expression J. Biol. Chem. 1994, 269, 12032-12039
    • (1994) J. Biol. Chem. , vol.269 , pp. 12032-12039
    • Lee, W.S.1    Kanai, Y.2    Wells, R.G.3    Hediger, M.A.4
  • 28
    • 33847213858 scopus 로고    scopus 로고
    • Octn2-Mediated Carnitine Uptake in a Newly Discovered Human Proximal Tubule Cell Line (Caki-1)
    • Glube, N.; Closs, E.; Langguth, P. Octn2-Mediated Carnitine Uptake in a Newly Discovered Human Proximal Tubule Cell Line (Caki-1) Mol. Pharmaceutics 2007, 4, 160-168
    • (2007) Mol. Pharmaceutics , vol.4 , pp. 160-168
    • Glube, N.1    Closs, E.2    Langguth, P.3
  • 29
    • 0024466413 scopus 로고
    • Primary rabbit kidney proximal tubule cell cultures maintain differentiated functions when cultured in a hormonally defined serum-free medium
    • Taub, M.; Yang, I.; Wang, Y. Primary Rabbit Kidney Proximal Tubule Cell Cultures Maintain Differentiated Functions When Cultured in a Hormonally Defined Serum-Free Medium In Vitro Cell. Dev. Biol. 1989, 25, 770-775 (Pubitemid 19249944)
    • (1989) In Vitro Cellular and Developmental Biology - Animal , vol.25 , Issue.9 , pp. 770-775
    • Taub, M.L.1    Yang, I.S.2    Wang, Y.3
  • 30
    • 0029034922 scopus 로고
    • Consecutive Use of Hormonally Defined Serum-Free Media to Establish Highly Differentiated Human Renal Proximal Tubule Cells in Primary Culture
    • Courjault-Gautier, F.; Chevalier, J.; Abbou, C. C.; Chopin, D. K.; Toutain, H. J. Consecutive Use of Hormonally Defined Serum-Free Media to Establish Highly Differentiated Human Renal Proximal Tubule Cells in Primary Culture J. Am. Soc. Nephrol. 1995, 5, 1949-1963
    • (1995) J. Am. Soc. Nephrol. , vol.5 , pp. 1949-1963
    • Courjault-Gautier, F.1    Chevalier, J.2    Abbou, C.C.3    Chopin, D.K.4    Toutain, H.J.5
  • 31
    • 0025361522 scopus 로고
    • Primary culture of proximal tubular cells from normal rat kidney as an in vitro model to study mechanisms of nephrotoxicity: toxicity of nephrotoxicants at low concentrations during prolonged exposure
    • DOI 10.1016/0006-2952(90)90010-I
    • Boogaard, P. J.; Zoeteweij, J. P.; Van Berkel, T. J. C.; Van't Noordende, J. M.; Mulder, G. J.; Nagelkerke, J. F. Primary Culture of Proximal Tubular Cells from Normal Rat Kidney as an in Vitro Model to Study Mechanisms of Nephrotoxicity: Toxicity of Nephrotoxicants at Low Concentrations During Prolonged Exposure Biochem. Pharmacol. 1990, 39, 1335-1345 (Pubitemid 20119209)
    • (1990) Biochemical Pharmacology , vol.39 , Issue.8 , pp. 1335-1345
    • Boogaard, P.J.1    Zoeteweij, J.P.2    Van Berkel, T.J.C.3    Van't Noordende, J.M.4    Mulder, G.J.5    Nagelkerke, J.F.6
  • 32
    • 0035897142 scopus 로고    scopus 로고
    • Characterization of biotransformation enzyme activities in primary rat proximal tubular cells
    • DOI 10.1016/S0009-2797(01)00151-X, PII S000927970100151X
    • Schaaf, G. J.; de Groene, E. M.; Maas, R. F.; Commandeur, J. N. M.; Fink-Gremmels, J. Characterization of Biotransformation Enzyme Activities in Primary Rat Proximal Tubular Cells Chem.-Biol. Interact. 2001, 134, 167-190 (Pubitemid 32304509)
    • (2001) Chemico-Biological Interactions , vol.134 , Issue.2 , pp. 167-190
    • Schaaf, G.J.1    De Groene, E.M.2    Maas, R.F.3    Commandeur, J.N.M.4    Fink-Gremmels, J.5
  • 33
    • 0033659819 scopus 로고    scopus 로고
    • Physiological and Pharmacological Implications of Peptide Transporters, Pept1 and Pept2
    • Inui, K.-i.; Terada, T.; Masuda, S.; Saito, H. Physiological and Pharmacological Implications of Peptide Transporters, Pept1 and Pept2 Nephrol., Dial., Transplant. 2000, 15, 11-13
    • (2000) Nephrol., Dial., Transplant. , vol.15 , pp. 11-13
    • Inui, K.-I.1    Terada, T.2    Masuda, S.3    Saito, H.4
  • 35
    • 48849114009 scopus 로고    scopus 로고
    • Functional Characterization of Ergothioneine Transport by Rat Organic Cation/Carnitine Transporter Octn1 (Slc22a4)
    • Nakamura, T.; Yoshida, K.; Yabuuchi, H.; Maeda, T.; Tamai, I. Functional Characterization of Ergothioneine Transport by Rat Organic Cation/Carnitine Transporter Octn1 (Slc22a4) Biol. Pharm. Bull. 2008, 31, 1580-1584
    • (2008) Biol. Pharm. Bull. , vol.31 , pp. 1580-1584
    • Nakamura, T.1    Yoshida, K.2    Yabuuchi, H.3    Maeda, T.4    Tamai, I.5


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