Estrogen receptor-beta variants are associated with increased risk of Alzheimer's disease in women with Down syndrome

Dementia and Geriatric Cognitive Disorders

Volumn 32, Issue 4, 2012, Pages 241-249

  Zhao, Qi ^a   Lee, Joseph H ^a,b   Pang, Deborah ^a,c   Temkin, Alexis ^a   Park, Naeun ^a   Janicki, Sarah C ^a,b   Zigman, Warren B ^c   Silverman, Wayne ^d   Tycko, Benjamin ^a   Schupf, Nicole ^a  

^a NewYork Presbyterian Hospital   (United States)

^b Taub Institute for Research on Alzheimer's Disease and the Aging Brain and the Gertrude H Sergievsky Center   (United States)

^c NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^d JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Alzheimer's disease; Down syndrome; Estrogen; Estrogen receptor beta

Indexed keywords

ESTROGEN RECEPTOR BETA;

ADULT; AGED; ALZHEIMER DISEASE; ARTICLE; DISEASE PREDISPOSITION; DNA POLYMORPHISM; DOWN SYNDROME; ESTROGEN ACTIVITY; FEMALE; GENETIC VARIABILITY; GENOTYPE; HUMAN; MAJOR CLINICAL STUDY; POSTMENOPAUSE; PRIORITY JOURNAL; SINGLE NUCLEOTIDE POLYMORPHISM;

ADULT; AGED; ALLELES; ALZHEIMER DISEASE; APOLIPOPROTEINS E; BODY MASS INDEX; COHORT STUDIES; DEMENTIA; DNA; DOWN SYNDROME; ESTROGEN RECEPTOR BETA; ETHNIC GROUPS; FEMALE; GENETIC VARIATION; GENOTYPE; HAPLOTYPES; HUMANS; INTELLECTUAL DISABILITY; INTRONS; LINKAGE DISEQUILIBRIUM; MENOPAUSE; MIDDLE AGED; POLYMORPHISM, SINGLE NUCLEOTIDE; PROPORTIONAL HAZARDS MODELS; RISK;

EID: 82955165876     PISSN: 14208008     EISSN: 14219824     Source Type: Journal    
DOI: 10.1159/000334522     Document Type: Article

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