Novel Rhein Analogues as Potential Anticancer Agents

ChemMedChem

Volumn 6, Issue 12, 2011, Pages 2294-2301

  Yang, Xiaochuan ^a   Sun, Guojing ^a   Yang, Chunhao ^a,b   Wang, Binghe ^a  

^a GEORGIA STATE UNIVERSITY   (United States)

^b SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Alkylating agents; Anthraquinones; Anticancer agents; Cytotoxicity; DNA intercalators; Rhein analogues

Indexed keywords

1,8 DIHYDROXY 3 (2' CHLORO ACETAMIDO)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (2' DIETHYLAMINOACETAMIDO)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (2' MORPHOLINO ACETAMIDO)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (2' PIPERIDINYL ACETAMIDO)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (3',5' DIMETHYL ISOXAZOL 4' YL)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (4' DIMETHYLAMINO 3' METHYLPHENYL)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (4' HYDROXYPHENYL)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (4' METHOXYPHENYL)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (4' TERT BUTOXYMETHYL PHENYL)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (6' PHENYLTHIO PYRIDIN 3' YL)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (PHENYLTHIO)ANTHRAQUINONE; 1,8 DIHYDROXY 3 (THIOPHEN 2' YL)ANTHRAQUINONE; 1,8 DIHYDROXY 3 [2' (4'' METHYLPIPERAZIN 1'' YL)ACETAMIDO]ANTHRAQUINONE; 1,8 DIHYDROXY 3 AMINOANTHRAQUINONE; 1,8 DIMETHOXY 3 (3',5' DIMETHYL ISOXAZOL 4' YL)ANTHRAQUINONE; 1,8 DIMETHOXY 3 (4' ACETYLPHENYL)ANTHRAQUINONE; 1,8 DIMETHOXY 3 (4' DIMETHYLAMINO 3' METHYLPHENYL)ANTHRAQUINONE; 1,8 DIMETHOXY 3 (4' METHOXYPHENYL)ANTHRAQUINONE; 1,8 DIMETHOXY 3 (4' TERT BUTOXYMETHYL PHENYL)ANTHRAQUINONE; 1,8 DIMETHOXY 3 (6' FLUOROPYRIDIN 3' YL)ANTHRAQUINONE; 1,8 DIMETHOXY 3 (FURAN 2' YL)ANTHRAQUINONE; 1,8 DIMETHOXY 3 (PYRIDIN 3' YL)ANTHRAQUINONE; 1,8 DIMETHOXY 3 (THIOPHEN 2' YL)ANTHRAQUINONE; 1,8 DIMETHOXY 3 AMINOANTHRAQUINONE; 1,8 DIMETHOXY 3 CARBOXY ANTHRAQUINONE; 1,8 DIMETHOXY 3 IODO ANTHRAQUINONE; 1,8 DIMETHOXY 3 METHYLCARBOXYLATE ANTHRAQUINONE; 1,8 DIMETHOXY ANTHRAQUINONE 3 CARBOXYL AZIDE; ANTINEOPLASTIC AGENT; RHEIN DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; DEMETHYLATION; DRUG POTENCY; DRUG SYNTHESIS; EVALUATION; HELA CELL; HUMAN; HUMAN CELL; IC 50; NITROBLUE TETRAZOLIUM TEST; PRIORITY JOURNAL;

ANTHRAQUINONES; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; HUMANS; NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 82955165635     PISSN: 18607179     EISSN: 18607187     Source Type: Journal    
DOI: 10.1002/cmdc.201100384     Document Type: Article

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