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Volumn 4, Issue 6, 2011, Pages 361-373

Natural toxins implicated in the development of Parkinson's disease

Author keywords

animal models; natural toxins; Parkinson's disease; therapeutic testing

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ANNONACIN; DOPAMINE; EPOXOMICIN; GLUCOSIDE; LEUCINE RICH REPEAT KINASE 2; NEUROTOXIN; OXIDOPAMINE; PARAQUAT; PESTICIDE; ROTENONE; STEROL;

EID: 82955164026     PISSN: 17562856     EISSN: 17562864     Source Type: Journal    
DOI: 10.1177/1756285611413004     Document Type: Article
Times cited : (19)

References (79)
  • 1
    • 77951909047 scopus 로고    scopus 로고
    • Environmental toxins and Parkinson's disease: putative roles of impaired electron transport chain and oxidative stress
    • Abdulwahid Arif I. Ahmad Khan H. (2010) Environmental toxins and Parkinson's disease: putative roles of impaired electron transport chain and oxidative stress. Toxicol Ind Health 26: 121–128.
    • (2010) Toxicol Ind Health , vol.26 , pp. 121-128
    • Abdulwahid Arif, I.1    Ahmad Khan, H.2
  • 4
    • 65549147233 scopus 로고    scopus 로고
    • Cycad seeds and chronic neurologic disease (Cycas species)
    • Barceloux D.G. (2009) Cycad seeds and chronic neurologic disease (Cycas species). Dis Mon 55: 353–360.
    • (2009) Dis Mon , vol.55 , pp. 353-360
    • Barceloux, D.G.1
  • 5
    • 33846849430 scopus 로고    scopus 로고
    • Nocardia asteroides strain GUH-2 induces proteasome inhibition and apoptotic death of cultured cells
    • Barry D.P. Beaman B.L. (2007) Nocardia asteroides strain GUH-2 induces proteasome inhibition and apoptotic death of cultured cells. Res Microbiol 158: 86–96.
    • (2007) Res Microbiol , vol.158 , pp. 86-96
    • Barry, D.P.1    Beaman, B.L.2
  • 6
    • 45849106495 scopus 로고    scopus 로고
    • An unusual murine behavior following infection with log-phase Nocardia asteroides type 6 strain GUH-2 (Nocardia cyriacigeorgica GUH-2)
    • Beaman B.L. Tam S. (2008) An unusual murine behavior following infection with log-phase Nocardia asteroides type 6 strain GUH-2 (Nocardia cyriacigeorgica GUH-2). Microbes Infect 10: 840–843.
    • (2008) Microbes Infect , vol.10 , pp. 840-843
    • Beaman, B.L.1    Tam, S.2
  • 7
    • 61649121516 scopus 로고    scopus 로고
    • The UPS and autophagy in chronic neurodegenerative disease: six of one and half a dozen of the other–or not?
    • Bedford L. Paine S. Rezvani N. Mee M. Lowe J. Mayer R.J. (2009) The UPS and autophagy in chronic neurodegenerative disease: six of one and half a dozen of the other–or not?. Autophagy 5: 224–227.
    • (2009) Autophagy , vol.5 , pp. 224-227
    • Bedford, L.1    Paine, S.2    Rezvani, N.3    Mee, M.4    Lowe, J.5    Mayer, R.J.6
  • 9
    • 0034993599 scopus 로고    scopus 로고
    • Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease
    • Blum D. Torch S. Lambeng N. Nissou M. Benabid A.L. Sadoul R. et al. (2001) Molecular pathways involved in the neurotoxicity of 6-OHDA, dopamine and MPTP: contribution to the apoptotic theory in Parkinson's disease. Prog Neurobiol 65: 135–172.
    • (2001) Prog Neurobiol , vol.65 , pp. 135-172
    • Blum, D.1    Torch, S.2    Lambeng, N.3    Nissou, M.4    Benabid, A.L.5    Sadoul, R.6
  • 11
    • 74549175646 scopus 로고    scopus 로고
    • Beyond Guam: the cyanobacteria / BMAA hypothesis of the cause of ALS and other neurodegenerative diseases
    • Bradley W.G. Mash D.C. (2009) Beyond Guam: the cyanobacteria / BMAA hypothesis of the cause of ALS and other neurodegenerative diseases. Amyotroph Lateral Scler 10(Suppl. 2): 7–20.
    • (2009) Amyotroph Lateral Scler , vol.10 , pp. 7-20
    • Bradley, W.G.1    Mash, D.C.2
  • 12
    • 70350230121 scopus 로고    scopus 로고
    • Investigating bacterial sources of toxicity as an environmental contributor to dopaminergic neurodegeneration
    • Caldwell K.A. Tucci M.L. Armagost J. Hodges T.W. Chen J. Memon S.B. et al. (2009) Investigating bacterial sources of toxicity as an environmental contributor to dopaminergic neurodegeneration. PloS ONE 4:e7227.
    • (2009) PloS ONE , vol.4 , pp. e7227
    • Caldwell, K.A.1    Tucci, M.L.2    Armagost, J.3    Hodges, T.W.4    Chen, J.5    Memon, S.B.6
  • 13
    • 26444595713 scopus 로고    scopus 로고
    • Atypical unclassifiable Parkinsonism on Guadeloupe: an environmental toxic hypothesis
    • Caparros-Lefebvre D. Lees A.J. (2005) Atypical unclassifiable Parkinsonism on Guadeloupe: an environmental toxic hypothesis. Mov Disord 20(Suppl. 12): S114–S118.
    • (2005) Mov Disord , vol.20 , pp. S114-S118
    • Caparros-Lefebvre, D.1    Lees, A.J.2
  • 14
    • 33751559873 scopus 로고    scopus 로고
    • Cycad neurotoxin, consumption of flying foxes, and ALS / PDC disease in Guam
    • author reply 1664-1665
    • Chen K.M. Craig U.K. Lee C.T. Haddock R. (2002) Cycad neurotoxin, consumption of flying foxes, and ALS / PDC disease in Guam. Neurology 59: 1664, author reply 1664-1665.
    • (2002) Neurology , vol.59 , pp. 1664
    • Chen, K.M.1    Craig, U.K.2    Lee, C.T.3    Haddock, R.4
  • 15
    • 0345255588 scopus 로고    scopus 로고
    • Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam
    • Cox P.A. Banack S.A. Murch S.J. (2003) Biomagnification of cyanobacterial neurotoxins and neurodegenerative disease among the Chamorro people of Guam. Proc Natl Acad Sci U S A 100: 13380–13383.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 13380-13383
    • Cox, P.A.1    Banack, S.A.2    Murch, S.J.3
  • 16
    • 0037177086 scopus 로고    scopus 로고
    • Cycad neurotoxins, consumption of flying foxes, and ALS-PDC disease in Guam
    • Cox P.A. Sacks O.W. (2002) Cycad neurotoxins, consumption of flying foxes, and ALS-PDC disease in Guam. Neurology 58: 956–959.
    • (2002) Neurology , vol.58 , pp. 956-959
    • Cox, P.A.1    Sacks, O.W.2
  • 17
    • 77950990463 scopus 로고    scopus 로고
    • Metabotropic glutamate receptor 1 mediates the electrophysiological and toxic actions of the cycad derivative beta-N-Methylamino-L-alanine on substantia nigra pars compacta DAergic neurons
    • Cucchiaroni M.L. Viscomi M.T. Bernardi G. Molinari M. Guatteo E. Mercuri N.B. (2010) Metabotropic glutamate receptor 1 mediates the electrophysiological and toxic actions of the cycad derivative beta-N-Methylamino-L-alanine on substantia nigra pars compacta DAergic neurons. J Neurosci 30: 5176–5188.
    • (2010) J Neurosci , vol.30 , pp. 5176-5188
    • Cucchiaroni, M.L.1    Viscomi, M.T.2    Bernardi, G.3    Molinari, M.4    Guatteo, E.5    Mercuri, N.B.6
  • 18
    • 77953666105 scopus 로고    scopus 로고
    • Genetic animal models of Parkinson's disease
    • Dawson T.M. Ko H.S. Dawson V.L. (2010) Genetic animal models of Parkinson's disease. Neuron 66: 646–661.
    • (2010) Neuron , vol.66 , pp. 646-661
    • Dawson, T.M.1    Ko, H.S.2    Dawson, V.L.3
  • 20
  • 22
    • 5644293405 scopus 로고    scopus 로고
    • Evaluation of animal models of Parkinson's disease for neuroprotective strategies
    • Emborg M.E. (2004) Evaluation of animal models of Parkinson's disease for neuroprotective strategies. J Neurosci Methods 139: 121–143.
    • (2004) J Neurosci Methods , vol.139 , pp. 121-143
    • Emborg, M.E.1
  • 24
    • 69149089036 scopus 로고    scopus 로고
    • Molecular pathogenesis of Parkinson disease: insights from genetic studies
    • Gasser T. (2009) Molecular pathogenesis of Parkinson disease: insights from genetic studies. Expert Rev Mol Med 11: e22.
    • (2009) Expert Rev Mol Med , vol.11 , pp. e22
    • Gasser, T.1
  • 25
    • 23744438056 scopus 로고    scopus 로고
    • Swim-test as a function of motor impairment in MPTP model of Parkinson's disease: a comparative study in two mouse strains
    • Haobam R. Sindhu K.M. Chandra G. Mohanakumar K.P. (2005) Swim-test as a function of motor impairment in MPTP model of Parkinson's disease: a comparative study in two mouse strains. Behav Brain Res 163: 159–167.
    • (2005) Behav Brain Res , vol.163 , pp. 159-167
    • Haobam, R.1    Sindhu, K.M.2    Chandra, G.3    Mohanakumar, K.P.4
  • 26
    • 77957905690 scopus 로고    scopus 로고
    • Genetic analysis of pathways to Parkinson disease
    • Hardy J. (2010) Genetic analysis of pathways to Parkinson disease. Neuron 68: 201–206.
    • (2010) Neuron , vol.68 , pp. 201-206
    • Hardy, J.1
  • 27
    • 34249709931 scopus 로고    scopus 로고
    • TDP-43 is deposited in the Guam Parkinsonism-dementia complex brains
    • Hasegawa M. Arai T. Akiyama H. Nonaka T. Mori H. Hashimoto T. et al. (2007) TDP-43 is deposited in the Guam Parkinsonism-dementia complex brains. Brain 130: 1386–1394.
    • (2007) Brain , vol.130 , pp. 1386-1394
    • Hasegawa, M.1    Arai, T.2    Akiyama, H.3    Nonaka, T.4    Mori, H.5    Hashimoto, T.6
  • 28
    • 73049132762 scopus 로고
    • Parkinsonism-dementia complex, an endemic disease on the island of Guam: 1. Clinical features
    • Hirano A. Kurland L.T. Krooth R.S. Lessel S. (1961) Parkinsonism-dementia complex, an endemic disease on the island of Guam: 1. Clinical features. Brain 84: 642–661.
    • (1961) Brain , vol.84 , pp. 642-661
    • Hirano, A.1    Kurland, L.T.2    Krooth, R.S.3    Lessel, S.4
  • 29
    • 79952133911 scopus 로고    scopus 로고
    • Toxin-induced and genetic animal models of Parkinson's disease
    • Hisahara S. Shimohama S. (2010) Toxin-induced and genetic animal models of Parkinson's disease. Parkinsons Dis 2011: 951709.
    • (2010) Parkinsons Dis , vol.2011 , pp. 951709
    • Hisahara, S.1    Shimohama, S.2
  • 30
    • 33750289169 scopus 로고    scopus 로고
    • The rotenone model of Parkinsonism–the five years inspection
    • Höglinger G.U. Oertel W.H. Hirsch E.C. (2006) The rotenone model of Parkinsonism–the five years inspection. J Neural Transm Suppl 70: 269–272.
    • (2006) J Neural Transm Suppl , vol.70 , pp. 269-272
    • Höglinger, G.U.1    Oertel, W.H.2    Hirsch, E.C.3
  • 31
    • 70349798628 scopus 로고    scopus 로고
    • Natural lipophilic inhibitors of mitochondrial complex I are candidate toxins for sporadic neurodegenerative tau pathologies
    • Höllerhage M. Matusch A. Champy P. Lombes A. Ruberg M. Oertel W.H. et al. (2009) Natural lipophilic inhibitors of mitochondrial complex I are candidate toxins for sporadic neurodegenerative tau pathologies. Exp Neurol 220: 133–142.
    • (2009) Exp Neurol , vol.220 , pp. 133-142
    • Höllerhage, M.1    Matusch, A.2    Champy, P.3    Lombes, A.4    Ruberg, M.5    Oertel, W.H.6
  • 32
    • 0034110714 scopus 로고    scopus 로고
    • Monoamine changes in the brain of BALB / c mice following sub-lethal infection with Nocardia asteroides (GUH-2)
    • Hyland K. Beaman B.L. LeWitt P.A. de Maggio A.J. (2000) Monoamine changes in the brain of BALB / c mice following sub-lethal infection with Nocardia asteroides (GUH-2). Neurochem Res 25: 443–448.
    • (2000) Neurochem Res , vol.25 , pp. 443-448
    • Hyland, K.1    Beaman, B.L.2    LeWitt, P.A.3    de Maggio, A.J.4
  • 33
    • 9344235042 scopus 로고    scopus 로고
    • 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned model of Parkinson's disease, with emphasis on mice and nonhuman primates
    • Jakowec M.W. Petzinger G.M. (2004) 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-lesioned model of Parkinson's disease, with emphasis on mice and nonhuman primates. Comp Med 54: 497–513.
    • (2004) Comp Med , vol.54 , pp. 497-513
    • Jakowec, M.W.1    Petzinger, G.M.2
  • 34
    • 77952691532 scopus 로고    scopus 로고
    • Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure
    • Jonasson S. Eriksson J. Berntzon L. Spacil Z. Ilag L.L. Ronnevi L.O. et al. (2010) Transfer of a cyanobacterial neurotoxin within a temperate aquatic ecosystem suggests pathways for human exposure. Proc Natl Acad Sci U S A 107: 9252–9257.
    • (2010) Proc Natl Acad Sci U S A , vol.107 , pp. 9252-9257
    • Jonasson, S.1    Eriksson, J.2    Berntzon, L.3    Spacil, Z.4    Ilag, L.L.5    Ronnevi, L.O.6
  • 35
    • 38349089902 scopus 로고    scopus 로고
    • Animal models of BMAA neurotoxicity: a critical review
    • Karamyan V.T. Speth R.C. (2008) Animal models of BMAA neurotoxicity: a critical review. Life Sci 82: 233–246.
    • (2008) Life Sci , vol.82 , pp. 233-246
    • Karamyan, V.T.1    Speth, R.C.2
  • 36
    • 71549147550 scopus 로고    scopus 로고
    • Vertical grid test and modified horizontal grid test are sensitive methods for evaluating motor dysfunctions in the MPTP mouse model of Parkinson's disease
    • Kim S.T. Son H.J. Choi J.H. Ji I.J. Hwang O. (2010) Vertical grid test and modified horizontal grid test are sensitive methods for evaluating motor dysfunctions in the MPTP mouse model of Parkinson's disease. Brain Res 1306: 176–183.
    • (2010) Brain Res , vol.1306 , pp. 176-183
    • Kim, S.T.1    Son, H.J.2    Choi, J.H.3    Ji, I.J.4    Hwang, O.5
  • 37
    • 0026098843 scopus 로고
    • L-dopa-responsive movement disorder caused by Nocardia asteroides localized in the brains of mice
    • Kohbata S. Beaman B.L. (1991) L-dopa-responsive movement disorder caused by Nocardia asteroides localized in the brains of mice. Infect Immun 59: 181–191.
    • (1991) Infect Immun , vol.59 , pp. 181-191
    • Kohbata, S.1    Beaman, B.L.2
  • 38
    • 0037320211 scopus 로고    scopus 로고
    • A clinical and pathological study of a Japanese case of Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex with family history
    • Konagaya M. Kato T. Sakai M. Kuru S. Matsuoka Y. Konagaya Y. et al. (2003) A clinical and pathological study of a Japanese case of Amyotrophic Lateral Sclerosis/Parkinsonism-Dementia Complex with family history. J Neurol 250: 164–170.
    • (2003) J Neurol , vol.250 , pp. 164-170
    • Konagaya, M.1    Kato, T.2    Sakai, M.3    Kuru, S.4    Matsuoka, Y.5    Konagaya, Y.6
  • 39
    • 33746851988 scopus 로고    scopus 로고
    • Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys
    • Kordower J.H. Kanaan N.M. Chu Y. Suresh Babu R. Stansell J. III Terpstra B.T. et al. (2006) Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys. Ann Neurol 60: 264–268.
    • (2006) Ann Neurol , vol.60 , pp. 264-268
    • Kordower, J.H.1    Kanaan, N.M.2    Chu, Y.3    Suresh Babu, R.4    Stansell, J.5    Terpstra, B.T.6
  • 40
    • 46649111324 scopus 로고    scopus 로고
    • Animal models of Parkinson's disease and L-dopa induced dyskinesia: how close are we to the clinic?
    • Lane E. Dunnett S. (2008) Animal models of Parkinson's disease and L-dopa induced dyskinesia: how close are we to the clinic?. Psychopharmacology (Berl) 199: 303–312.
    • (2008) Psychopharmacology (Berl) , vol.199 , pp. 303-312
    • Lane, E.1    Dunnett, S.2
  • 41
    • 68649114338 scopus 로고    scopus 로고
    • Genetic models of Parkinson disease
    • Lim K.L. Ng C.H. (2009) Genetic models of Parkinson disease. Biochim Biophys Acta 1792: 604–615.
    • (2009) Biochim Biophys Acta , vol.1792 , pp. 604-615
    • Lim, K.L.1    Ng, C.H.2
  • 42
    • 33846318576 scopus 로고    scopus 로고
    • Beta-N-methylamino-L-alanine enhances neurotoxicity through multiple mechanisms
    • Lobner D. Piana P.M. Salous A.K. Peoples R.W. (2007) Beta-N-methylamino-L-alanine enhances neurotoxicity through multiple mechanisms. Neurobiol Dis 25: 360–366.
    • (2007) Neurobiol Dis , vol.25 , pp. 360-366
    • Lobner, D.1    Piana, P.M.2    Salous, A.K.3    Peoples, R.W.4
  • 43
    • 74149088770 scopus 로고    scopus 로고
    • Clinical neuroprotection in Parkinson's disease - still waiting for the breakthrough
    • Lohle M. Reichmann H. (2010) Clinical neuroprotection in Parkinson's disease - still waiting for the breakthrough. J Neurol Sci 289: 104–114.
    • (2010) J Neurol Sci , vol.289 , pp. 104-114
    • Lohle, M.1    Reichmann, H.2
  • 44
    • 0034624017 scopus 로고    scopus 로고
    • The Parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity
    • Lotharius J. O'Malley K.L. (2000) The Parkinsonism-inducing drug 1-methyl-4-phenylpyridinium triggers intracellular dopamine oxidation. A novel mechanism of toxicity. J Biol Chem 275: 38581–38588.
    • (2000) J Biol Chem , vol.275 , pp. 38581-38588
    • Lotharius, J.1    O'Malley, K.L.2
  • 45
    • 34548400209 scopus 로고    scopus 로고
    • Model fusion, the next phase in developing animal models for Parkinson's disease
    • Manning-Bog A.B. Langston J.W. (2007) Model fusion, the next phase in developing animal models for Parkinson's disease. Neurotox Res 11: 219–240.
    • (2007) Neurotox Res , vol.11 , pp. 219-240
    • Manning-Bog, A.B.1    Langston, J.W.2
  • 46
    • 77956568458 scopus 로고    scopus 로고
    • Proteasome inhibition in medaka brain induces the features of Parkinson's disease
    • Matsui H. Ito H. Taniguchi Y. Inoue H. Takeda S. Takahashi R. (2010) Proteasome inhibition in medaka brain induces the features of Parkinson's disease. J Neurochem 115: 178–187.
    • (2010) J Neurochem , vol.115 , pp. 178-187
    • Matsui, H.1    Ito, H.2    Taniguchi, Y.3    Inoue, H.4    Takeda, S.5    Takahashi, R.6
  • 47
    • 0037933427 scopus 로고    scopus 로고
    • From neurodegeneration to neurohomeostasis: the role of ubiquitin
    • Mayer R.J. (2003) From neurodegeneration to neurohomeostasis: the role of ubiquitin. Drug News Perspect 16: 103–108.
    • (2003) Drug News Perspect , vol.16 , pp. 103-108
    • Mayer, R.J.1
  • 48
    • 0036075892 scopus 로고    scopus 로고
    • Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat
    • McCormack A.L. Thiruchelvam M. Manning-Bog A.B. Thiffault C. Langston J.W. Cory-Slechta D.A. et al. (2002) Environmental risk factors and Parkinson's disease: selective degeneration of nigral dopaminergic neurons caused by the herbicide paraquat. Neurobiol Dis 10: 119–127.
    • (2002) Neurobiol Dis , vol.10 , pp. 119-127
    • McCormack, A.L.1    Thiruchelvam, M.2    Manning-Bog, A.B.3    Thiffault, C.4    Langston, J.W.5    Cory-Slechta, D.A.6
  • 49
    • 3042794162 scopus 로고    scopus 로고
    • Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease
    • McNaught K.S. Perl D.P. Brownell A.L. Olanow C.W. (2004) Systemic exposure to proteasome inhibitors causes a progressive model of Parkinson's disease. Ann Neurol 56: 149–162.
    • (2004) Ann Neurol , vol.56 , pp. 149-162
    • McNaught, K.S.1    Perl, D.P.2    Brownell, A.L.3    Olanow, C.W.4
  • 52
    • 4344626578 scopus 로고    scopus 로고
    • A mechanism for slow release of biomagnified cyanobacterial neurotoxins and neurodegenerative disease in Guam
    • Murch S.J. Cox P.A. Banack S.A. (2004) A mechanism for slow release of biomagnified cyanobacterial neurotoxins and neurodegenerative disease in Guam. Proc Natl Acad Sci U S A 101: 12228–12231.
    • (2004) Proc Natl Acad Sci U S A , vol.101 , pp. 12228-12231
    • Murch, S.J.1    Cox, P.A.2    Banack, S.A.3
  • 55
    • 78650789638 scopus 로고    scopus 로고
    • The neurotoxicity of DOPAL:behavioral and stereological evidence for its role in Parkinson disease pathogenesis
    • Panneton W.M. Kumar V.B. Gan Q. Burke W.J. Galvin J.E. (2010) The neurotoxicity of DOPAL:behavioral and stereological evidence for its role in Parkinson disease pathogenesis. PloS ONE 5: e15251.
    • (2010) PloS ONE , vol.5 , pp. e15251
    • Panneton, W.M.1    Kumar, V.B.2    Gan, Q.3    Burke, W.J.4    Galvin, J.E.5
  • 56
    • 23844483173 scopus 로고    scopus 로고
    • Superoxide dismutase / catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease
    • Peng J. Stevenson F.F. Doctrow S.R. Andersen J.K. (2005) Superoxide dismutase / catalase mimetics are neuroprotective against selective paraquat-mediated dopaminergic neuron death in the substantial nigra: implications for Parkinson disease. J Biol Chem 280: 29194–29198.
    • (2005) J Biol Chem , vol.280 , pp. 29194-29198
    • Peng, J.1    Stevenson, F.F.2    Doctrow, S.R.3    Andersen, J.K.4
  • 57
    • 77953367451 scopus 로고    scopus 로고
    • Risk factors for Parkinson disease: an epidemiologic study
    • Pereira D. Garrett C. (2010) [Risk factors for Parkinson disease: an epidemiologic study]. Acta Med Port 23: 15–24.
    • (2010) Acta Med Port , vol.23 , pp. 15-24
    • Pereira, D.1    Garrett, C.2
  • 58
    • 0035960066 scopus 로고    scopus 로고
    • Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP / probenecid treatment
    • Petroske E. Meredith G.E. Callen S. Totterdell S. Lau Y.S. (2001) Mouse model of Parkinsonism: a comparison between subacute MPTP and chronic MPTP / probenecid treatment. Neuroscience 106: 589–601.
    • (2001) Neuroscience , vol.106 , pp. 589-601
    • Petroske, E.1    Meredith, G.E.2    Callen, S.3    Totterdell, S.4    Lau, Y.S.5
  • 59
    • 33644648172 scopus 로고    scopus 로고
    • The role of oxidative stress in the dysregulation of gene expression and protein metabolism in neurodegenerative disease
    • Potashkin J.A. Meredith G.E. (2006) The role of oxidative stress in the dysregulation of gene expression and protein metabolism in neurodegenerative disease. Antioxid Redox Signal 8: 144–151.
    • (2006) Antioxid Redox Signal , vol.8 , pp. 144-151
    • Potashkin, J.A.1    Meredith, G.E.2
  • 61
    • 33747191785 scopus 로고    scopus 로고
    • BMAA selectively injures motor neurons via AMPA / kainate receptor activation
    • Rao S.D. Banack S.A. Cox P.A. Weiss J.H. (2006) BMAA selectively injures motor neurons via AMPA / kainate receptor activation. Exp Neurol 201: 244–252.
    • (2006) Exp Neurol , vol.201 , pp. 244-252
    • Rao, S.D.1    Banack, S.A.2    Cox, P.A.3    Weiss, J.H.4
  • 62
    • 37349085745 scopus 로고    scopus 로고
    • Moderate degeneration of nigral neurons after repeated but not after single intrastriatal injections of low doses of 6-hydroxydopamine in mice
    • Richter F. Hamann M. Richter A. (2008) Moderate degeneration of nigral neurons after repeated but not after single intrastriatal injections of low doses of 6-hydroxydopamine in mice. Brain Res 1188: 148–156.
    • (2008) Brain Res , vol.1188 , pp. 148-156
    • Richter, F.1    Hamann, M.2    Richter, A.3
  • 63
    • 0036316022 scopus 로고    scopus 로고
    • Cycads: their evolution, toxins, herbivores and insect pollinators
    • Schneider D. Wink M. Sporer F. Lounibos P. (2002) Cycads: their evolution, toxins, herbivores and insect pollinators. Naturwissenschaften 89: 281–294.
    • (2002) Naturwissenschaften , vol.89 , pp. 281-294
    • Schneider, D.1    Wink, M.2    Sporer, F.3    Lounibos, P.4
  • 64
    • 5544229693 scopus 로고    scopus 로고
    • Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP
    • Schober A. (2004) Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP. Cell Tissue Res 318: 215–224.
    • (2004) Cell Tissue Res , vol.318 , pp. 215-224
    • Schober, A.1
  • 65
    • 33645225002 scopus 로고    scopus 로고
    • Cycad toxins, Helicobacter pylori and Parkinsonism: cholesterol glucosides as the common denomenator
    • Schulz J.D. Hawkes E.L. Shaw C.A. (2006) Cycad toxins, Helicobacter pylori and Parkinsonism: cholesterol glucosides as the common denomenator. Med Hypotheses 66: 1222–1226.
    • (2006) Med Hypotheses , vol.66 , pp. 1222-1226
    • Schulz, J.D.1    Hawkes, E.L.2    Shaw, C.A.3
  • 66
    • 49249112467 scopus 로고    scopus 로고
    • Neurodegenerative diseases: neurotoxins as sufficient etiologic agents?
    • Shaw C.A. Hoglinger G.U. (2008) Neurodegenerative diseases: neurotoxins as sufficient etiologic agents?. Neuromolecular Med 10: 1–9.
    • (2008) Neuromolecular Med , vol.10 , pp. 1-9
    • Shaw, C.A.1    Hoglinger, G.U.2
  • 69
    • 0036716889 scopus 로고    scopus 로고
    • MPTP: insights into Parkinsonian neurodegeneration
    • Speciale S.G. (2002) MPTP: insights into Parkinsonian neurodegeneration. Neurotoxicol Teratol 24: 607–620.
    • (2002) Neurotoxicol Teratol , vol.24 , pp. 607-620
    • Speciale, S.G.1
  • 70
    • 0023181410 scopus 로고
    • Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin
    • Spencer P.S. Nunn P.B. Hugon J. Ludolph A.C. Ross S.M. Roy D.N. et al. (1987) Guam amyotrophic lateral sclerosis-parkinsonism-dementia linked to a plant excitant neurotoxin. Science 237 (4814): 517–522.
    • (1987) Science , vol.237 , Issue.4814 , pp. 517-522
    • Spencer, P.S.1    Nunn, P.B.2    Hugon, J.3    Ludolph, A.C.4    Ross, S.M.5    Roy, D.N.6
  • 71
    • 61549123659 scopus 로고    scopus 로고
    • The ALS / PDC syndrome of Guam and the cycad hypothesis
    • author reply 475-476
    • Spencer P.S. Palmer V. Kisby G. (2009) The ALS / PDC syndrome of Guam and the cycad hypothesis. Neurology 72: 474–476, author reply 475-476.
    • (2009) Neurology , vol.72 , pp. 474-476
    • Spencer, P.S.1    Palmer, V.2    Kisby, G.3
  • 72
    • 26444509015 scopus 로고    scopus 로고
    • On the decline and etiology of high-incidence motor system disease in West Papua (southwest New Guinea)
    • Spencer P.S. Palmer V.S. Ludolph A.C. (2005) On the decline and etiology of high-incidence motor system disease in West Papua (southwest New Guinea). Mov Disord 20(Suppl. 12): S119–S126.
    • (2005) Mov Disord , vol.20 , pp. S119-S126
    • Spencer, P.S.1    Palmer, V.S.2    Ludolph, A.C.3
  • 73
    • 0036436244 scopus 로고    scopus 로고
    • Neuroinvasive Nocardia asteroides GUH-2 induces apoptosis in the substantia nigra in vivo and dopaminergic cells in vitro
    • Tam S. Barry D.P. Beaman L. Beaman B.L. (2002) Neuroinvasive Nocardia asteroides GUH-2 induces apoptosis in the substantia nigra in vivo and dopaminergic cells in vitro. Exp Neurol 177: 453–460.
    • (2002) Exp Neurol , vol.177 , pp. 453-460
    • Tam, S.1    Barry, D.P.2    Beaman, L.3    Beaman, B.L.4
  • 74
    • 77953468252 scopus 로고    scopus 로고
    • Advances in environmental epidemiology
    • Tanner C.M. (2010) Advances in environmental epidemiology. Mov Disord 25(Suppl. 1): S58–S62.
    • (2010) Mov Disord , vol.25 , pp. S58-S62
    • Tanner, C.M.1
  • 75
    • 0037445497 scopus 로고    scopus 로고
    • Grid performance test to measure behavioral impairment in the MPTP-treated-mouse model of Parkinsonism
    • Tillerson J.L. Miller G.W. (2003) Grid performance test to measure behavioral impairment in the MPTP-treated-mouse model of Parkinsonism. J Neurosci Methods 123: 189–200.
    • (2003) J Neurosci Methods , vol.123 , pp. 189-200
    • Tillerson, J.L.1    Miller, G.W.2
  • 76
    • 27744491956 scopus 로고    scopus 로고
    • Pathological tau: a loss of normal function or a gain in toxicity?
    • Trojanowski J.Q. Lee V.M. (2005) Pathological tau: a loss of normal function or a gain in toxicity?. Nat Neurosci 8: 1136–1137.
    • (2005) Nat Neurosci , vol.8 , pp. 1136-1137
    • Trojanowski, J.Q.1    Lee, V.M.2
  • 77
    • 0014376793 scopus 로고
    • 6-Hydroxy-dopamine induced degeneration of central monoamine neurons
    • Ungerstedt U. (1968) 6-Hydroxy-dopamine induced degeneration of central monoamine neurons. Eur J Pharmacol 5: 107–110.
    • (1968) Eur J Pharmacol , vol.5 , pp. 107-110
    • Ungerstedt, U.1
  • 78
    • 5444255433 scopus 로고    scopus 로고
    • Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration
    • Uversky V.N. (2004) Neurotoxicant-induced animal models of Parkinson's disease: understanding the role of rotenone, maneb and paraquat in neurodegeneration. Cell Tissue Res 318: 225–241.
    • (2004) Cell Tissue Res , vol.318 , pp. 225-241
    • Uversky, V.N.1
  • 79
    • 33750370804 scopus 로고    scopus 로고
    • Understanding the molecular causes of Parkinson's disease
    • Wood-Kaczmar A. Gandhi S. Wood N.W. (2006) Understanding the molecular causes of Parkinson's disease. Trends Mol Med 12: 521–528.
    • (2006) Trends Mol Med , vol.12 , pp. 521-528
    • Wood-Kaczmar, A.1    Gandhi, S.2    Wood, N.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.