Sulfatide-activated type II NKT cells prevent allergic airway inflammation by inhibiting type I NKT cell function in a mouse model of asthma

American Journal of Physiology - Lung Cellular and Molecular Physiology

Volumn 301, Issue 6, 2011, Pages

  Zhang, Guqin ^a   Nie, Hanxiang ^b   Yang, Jiong ^a   Ding, Xuhong ^b   Huang, Yi ^b   Yu, Hongying ^b   Li, Ruyou ^b   Yuan, Zhuqing ^b   Hu, Suping ^b  

^a ZHONGNAN HOSPITAL OF WUHAN UNIVERSITY   (China)

^b RENMIN HOSPITAL OF WUHAN UNIVERSITY   (China)

Author keywords

Natural killer t cell

Indexed keywords

IMMUNOGLOBULIN E; IMMUNOGLOBULIN G1; INTERLEUKIN 4; INTERLEUKIN 5; OVALBUMIN; SULFATIDE;

ALLERGIC AIRWAY INFLAMMATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; CELL FUNCTION; CELL HYPERPLASIA; CELL INFILTRATION; CONTROLLED STUDY; FEMALE; GOBLET CELL; GOBLET CELL HYPERPLASIA; LUNG LAVAGE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PRIORITY JOURNAL; RESPIRATORY TRACT ALLERGY; TYPE 2 NATURAL KILLER T;

ADOPTIVE TRANSFER; ANIMALS; ASTHMA; BRONCHOALVEOLAR LAVAGE FLUID; FEMALE; GOBLET CELLS; HYPERPLASIA; IMMUNOGLOBULIN E; IMMUNOGLOBULIN G; INTERLEUKIN-4; INTERLEUKIN-5; LUNG; MICE; MICE, INBRED BALB C; NATURAL KILLER T-CELLS; OVALBUMIN; RESPIRATORY MUCOSA; SULFOGLYCOSPHINGOLIPIDS;

EID: 82855167203     PISSN: 10400605     EISSN: 15221504     Source Type: Journal    
DOI: 10.1152/ajplung.00114.2011     Document Type: Article

References (29)

1. Akbari O, Faul JL, Hoyte EG, Berry GJ, Wahlstrom J, Kronenberg M, DeKruyff RH, Umetsu DT. CD4+ invariant T-cell-receptor+ natural killer T cells in bronchial asthma. N Engl J Med 354: 1117-1129, 2006.
2. Akbari O, Stock P, Meyer E, Kronenberg M, Sidobre S, Nakayama T, Taniguchi M, Grusby MJ, DeKruyff RH, Umetsu DT. Essential role of NKT cells producing IL-4 and IL-13 in the development of allergeninduced airway hyperreactivity. Nat Med 9: 582-588, 2003.
3. Ambrosino E, Terabe M, Halder RC, Peng J, Takaku S, Miyake S, Yamamura T, Kumar V, Berzofsky JA. Cross-regulation between type I and type II NKT cells in regulating tumor immunity: a new immunoregulatory axis. J Immunol 179: 5126-5136, 2007.
4. Arrenberg P, Halder R, Dai Y, Maricic I, Kumar V. Oligoclonality and innate-like features in the TCR repertoire of type II NKT cells reactive to a beta-linked self-glycolipid. Proc Natl Acad Sci USA 107: 10984-10989, 2010.
5. Arrenberg P, Maricic I, Kumar V. Sulfatide-mediated activation of type II natural killer T cells prevents hepatic ischemic reperfusion injury in mice. Gastroenterology 140: 646-655, 2011.
6. Balato A, Unutmaz D, Gaspari AA. Natural killer T cells: an unconventional T-cell subset with diverse effector and regulatory functions. J Invest Dermatol 129: 1628-1642, 2009.
7. Blomqvist M, Rhost S, Teneberg S, Lofbom L, Osterbye T, Brigl M, Mansson JE, Cardell SL. Multiple tissue-specific isoforms of sulfatide activate CD1d-restricted type II NKT cells. Eur J Immunol 39: 1726-1735, 2009.
8. Burrows B, Martinez FD, Halonen M, Barbee RA, Cline MG. Association of asthma with serum IgE levels and skin-test reactivity to allergens. N Engl J Med 320: 271-277, 1989.
9. Busse WW, Lemanske Jr RF. Asthma. N Engl J Med 344: 350-362, 2001.
10. Duarte N, Stenstrom M, Campino S, Bergman ML, Lundholm M, Holmberg D, Cardell SL. Prevention of diabetes in nonobese diabetic mice mediated by CD1d-restricted nonclassical NKT cells. J Immunol 173: 3112-3118, 2004.
11. Duthie MS, Kahn M, White M, Kapur RP, Kahn SJ. Critical proinflammatory and anti-inflammatory functions of different subsets of CD1drestricted natural killer T cells during Trypanosoma cruzi infection. Infect Immun 73: 181-192, 2005.
12. Halder RC, Aguilera C, Maricic I, Kumar V. Type II NKT cellmediated anergy induction in type I NKT cells prevents inflammatory liver disease. J Clin Invest 117: 2302-2312, 2007.
13. Illi S, von Mutius E, Lau S, Nickel R, Niggemann B, Sommerfeld C, Wahn U. The pattern of atopic sensitization is associated with the development of asthma in childhood. J Allergy Clin Immunol 108: 709-714, 2001.
14. Iwamura C, Nakayama T. Role of NKT cells in allergic asthma. Curr Opin Immunol 22: 807-813, 2010.
15. Jahng A, Maricic I, Aguilera C, Cardell S, Halder RC, Kumar V. Prevention of autoimmunity by targeting a distinct, noninvariant CD1dreactive T cell population reactive to sulfatide. J Exp Med 199: 947-957, 2004.
16. Kim HY, DeKruyff RH, Umetsu DT. The many paths to asthma: phenotype shaped by innate and adaptive immunity. Nat Immunol 11: 577-584, 2010.
17. Koyasu S, Moro K. Type 2 innate immune responses and the natural helper cell. Immunology 132: 475-481, 2011.
18. Liu Y, Goff RD, Zhou D, Mattner J, Sullivan BA, Khurana A, Cantu C 3rd, Ravkov EV, Ibegbu CC, Altman JD, Teyton L, Bendelac A, Savage PB. A modified-galactosyl ceramide for staining and stimulating natural killer T cells. J Immunol Methods 312: 34-39, 2006.
19. Lisbonne M, Diem S, de Castro Keller A, Lefort J, Araujo LM, Hachem P, Fourneau JM, Sidobre S, Kronenberg M, Taniguchi M, Van Endert P, Dy M, Askenase P, Russo M, Vargaftig BB, Herbelin A, Leite-de-Moraes MC. Cutting edge: invariant V alpha 14 NKT cells are required for allergen-induced airway inflammation and hyperreactivity in an experimental asthma model. J Immunol 171: 1637-1641, 2003.
20. Matangkasombut P, Marigowda G, Ervine A, Idris L, Pichavant M, Kim HY, Yasumi T, Wilson SB, DeKruyff RH, Faul JL, Israel E, Akbari O, Umetsu DT. Natural killer T cells in the lungs of patients with asthma. J Allergy Clin Immunol 123: 1181-1185, 2009.
21. Martinez FD, Wright AL, Taussig LM, Holberg CJ, Halonen M, Morgan WJ. Asthma and wheezing in the first six years of life. The Group Health Medical Associates. N Engl J Med 332: 133-138, 1995.
22. Meyer EH, Goya S, Akbari O, Berry GJ, Savage PB, Kronenberg M, Nakayama T, DeKruyff RH, Umetsu DT. Glycolipid activation of invariant T cell receptor+ NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4+ T cells. Proc Natl Acad Sci USA 103: 2782-2787, 2006.
23. Reynolds C, Barkans J, Clark P, Kariyawasam H, Altmann D, Kay B, Boyton R. Natural killer T cells in bronchial biopsies from human allergen challenge model of allergic asthma. J Allergy Clin Immunol 124: 860-862, 2009.
24. Rolf J, Berntman E, Stenstrom M, Smith EM, Månsson R, Stenstad H, Yamagata T, Agace W, Sigvardsson M, Cardell SL. Molecular profiling reveals distinct functional attributes of CD1d-restricted natural killer (NK) T cell subsets. Mol Immunol 45: 2607-2620, 2008.
25. Stenstrom M, Skold M, Ericsson A, Beaudoin L, Sidobre S, Kronenberg M, Lehuen A, Cardell S. Surface receptors identify mouse NK1.1+ T cell subsets distinguished by function and T cell receptor type. Eur J Immunol 34: 56-65, 2004.
26. Terabe M, Swann J, Ambrosino E, Sinha P, Takaku S, Hayakawa Y, Godfrey DI, Ostrand-Rosenberg S, Smyth MJ, Berzofsky JA. A nonclassical non-Valpha14Jalpha18 CD1d-restricted (type II) NKT cell is sufficient for down-regulation of tumor immunosurveillance. J Exp Med 202: 1627-1633, 2005.
27. Watarai H, Nakagawa R, Omori-Miyake M, Dashtsoodol N, Taniguchi M. Methods for detection, isolation and culture of mouse and human invariant NKT cells. Nat Protoc 3: 70-78, 2008.
28. Yamamoto H, Okamoto Y, Horiguchi S, Kunii N, Yonekura S, Nakayama T. Detection of natural killer T cells in the sinus mucosa from asthmatics with chronic sinusitis. Allergy 62: 1451-1455, 2007.
29. Yang SH, Lee JP, Jang HR, Cha RH, Han SS, Jeon US, Kim DK, Song J, Lee DS, Kim YS. Sulfatide-reactive Natural Killer T Cells Abrogate Ischemia-Reperfusion Injury. J Am Soc Nephrol 22: 1305-1314, 2011.