A dual role for diacylglycerol kinase generated phosphatidic acid in autoantibody-induced neutrophil exocytosis

Molecular Medicine

Volumn 17, Issue 11, 2011, Pages 1242-1252

  Holden, Neil J ^a   Savage, Caroline O S ^a   Young, Stephen P ^a   Wakelam, Michael J ^b   Harper, Lorraine ^a   Williams, Julie M ^c  

^a UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^b BABRAHAM INSTITUTE   (United Kingdom)

^c WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

6 [2 [4 [(4 FLUOROPHENYL)PHENYLMETHYLENE] 1 PIPERIDYL]ETHYL] 7 METHYL 5H THIAZOLO[3,2 A]PYRIMIDIN 5 ONE; AUTOANTIBODY; CALCIUM; DIACYLGLYCEROL KINASE; NEUTROPHIL CYTOPLASMIC ANTIBODY; PHOSPHATIDIC ACID;

ARTICLE; CALCIUM CELL LEVEL; CELL MEMBRANE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG TARGETING; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INHIBITION; EXOCYTOSIS; HUMAN; HUMAN CELL; IMMUNOMODULATION; IMMUNOREACTIVITY; IN VITRO STUDY; LIPOGENESIS; MEMBRANE FUSION; NEUTROPHIL; PRIORITY JOURNAL; SIGNAL TRANSDUCTION;

ACTIN CYTOSKELETON; ACTINS; ANTIBODIES, ANTINEUTROPHIL CYTOPLASMIC; ANTIGENS, CD63; CALCIUM; CYTOPLASMIC GRANULES; DIACYLGLYCEROL KINASE; ENZYME ACTIVATION; EXOCYTOSIS; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; IMMUNOGLOBULIN G; INTRACELLULAR SPACE; IONOMYCIN; LYSOPHOSPHATIDYLCHOLINES; MEMBRANE FUSION; NEUTROPHILS; PEROXIDASE; PHOSPHATIDIC ACIDS; PYRIMIDINONES; THIAZOLES;

EID: 82855164054     PISSN: 10761551     EISSN: None     Source Type: Journal    
DOI: 10.2119/molmed.2011.00028     Document Type: Article

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