Cyclosporine A-loaded and stem cell-seeded electrospun nanofibers for cell-based therapy and local immunosuppression

Journal of Controlled Release

Volumn 156, Issue 3, 2011, Pages 406-412

  Holan, Vladimir ^a,b   Chudickova, Milada ^a,b   Trosan, Peter ^a,b   Svobodova, Eliska ^a,b   Krulova, Magdalena ^a,b   Kubinova, Sarka ^c   Sykova, Eva ^c   Sirc, Jakub ^d   Michalek, Jiri ^d   Juklickova, Martina ^e   Munzarova, Marcela ^e   Zajicova, Alena ^a  

^a INSTITUTE OF MOLECULAR GENETICS   (Czech Republic)

^b CHARLES UNIVERSITY   (Czech Republic)

^c INSTITUTE OF EXPERIMENTAL MEDICINE   (Czech Republic)

^d INSTITUTE OF MACROMOLECULAR CHEMISTRY   (Czech Republic)

^e Elmarco   (Czech Republic)

Author keywords

Cyclosporine A; Immunosuppression; Inflammation; Nanofibers; Poly(L lactic acid)

Indexed keywords

CELL-BASED THERAPY; CONCANAVALIN A; CULTURE MEDIUM; CYCLOSPORINE A; DRUG CARRIER; ELECTROSPINNING PROCESS; ELECTROSPUN NANOFIBERS; IMMUNOSUPPRESSION; IMMUNOSUPPRESSIVE DRUGS; IN-VIVO; INFLAMMATION; INFLAMMATORY REACTION; LOCAL PRODUCTION; LOW WATER; PHARMACOLOGICAL ACTIVITY; POLY L LACTIC ACID; PROINFLAMMATORY CYTOKINES; RELEASE BEHAVIORS; SPLEEN CELLS; T CELLS; TOPICAL APPLICATION;

CELL PROLIFERATION; DRUG THERAPY; ELECTROSPINNING; LACTIC ACID; NANOFIBERS; POPULATION STATISTICS; SCAFFOLDS (BIOLOGY); STEM CELLS;

CELL CULTURE;

CONCANAVALIN A; CYCLOSPORIN A; GAMMA INTERFERON; INTERLEUKIN 17; INTERLEUKIN 2; NANOCARRIER; NANOFIBER; POLYLACTIC ACID;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG RELEASE; DRUG RETENTION; ELECTROSPINNING; FEMALE; IMMUNOSUPPRESSIVE TREATMENT; IN VIVO STUDY; MACROPHAGE ACTIVATION; MALE; MOUSE; NANOFABRICATION; NONHUMAN; PRIORITY JOURNAL; SKIN ALLOGRAFT; SPLEEN CELL; STEM CELL TRANSPLANTATION; TOPICAL TREATMENT;

ANIMALS; CELL PROLIFERATION; CELLS, CULTURED; CYCLOSPORINE; CYTOKINES; DRUG CARRIERS; IMMUNOSUPPRESSIVE AGENTS; LACTIC ACID; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; NANOFIBERS; POLYMERS; SKIN TRANSPLANTATION; T-LYMPHOCYTES;

EID: 82755197882     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2011.07.022     Document Type: Article

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