Rescue of ATP7B function in hepatocyte-like cells from Wilson's disease induced pluripotent stem cells using gene therapy or the chaperone drug curcumin

Human Molecular Genetics

Volumn 20, Issue 16, 2011, Pages 3176-3187

  Zhang, Shiqiang ^a   Chen, Shen ^a   Li, Wen ^a   Guo, Xiangpeng ^a   Zhao, Ping ^a   Xu, Jianyong ^a   Chen, Yan ^b   Pan, Qiong ^b   Liu, Xiaorong ^b   Zychlinski, Daniela ^c   Lu, Hai ^d   Tortorella, Micky D ^b   Schambach, Axel ^c   Wang, Yan ^d   Pei, Duanqing ^a   Esteban, Miguel A ^a  

^a South China Institute for Stem Cell Biology and Regenerative Medicine   (China)

^b GUANGZHOU INSTITUTES OF BIOMEDICINE AND HEALTH   (China)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d SOUTHERN MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CHAPERONE; COPPER; CURCUMIN; LENTIVIRUS VECTOR; WILSON DISEASE PROTEIN;

ADULT; ARTICLE; CASE REPORT; CELL DIFFERENTIATION; CELL LINE; CELLULAR DISTRIBUTION; CHINESE; CODON; CONTROLLED STUDY; CYTOPLASM; GENE MUTATION; GENE THERAPY; GENETIC STABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIVER CELL; MALE; PLURIPOTENT STEM CELL; PRIORITY JOURNAL; PROTEIN FUNCTION; WILSON DISEASE;

ADENOSINE TRIPHOSPHATASES; BASE SEQUENCE; CATION TRANSPORT PROTEINS; COPPER; CURCUMIN; GENE THERAPY; HEPATOCYTES; HEPATOLENTICULAR DEGENERATION; HUMANS; INDUCED PLURIPOTENT STEM CELLS; MALE; MIDDLE AGED; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; MUTATION; PROTEIN TRANSPORT; SUBCELLULAR FRACTIONS;

EID: 79960831061     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddr223     Document Type: Article

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