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Volumn 301, Issue 6, 2011, Pages

Rate of fall in blood glucose and recurrent hypoglycemia affect glucose dynamics and noradrenergic activation in the ventromedial hypothalamus

Author keywords

Glucose homeostasis; Hypoglycemia associated autonomic failure; Recurrent hypoglycemia; Sympathoadrenal response

Indexed keywords

INSULIN; NORADRENALIN;

EID: 82755186779     PISSN: 03636119     EISSN: 15221490     Source Type: Journal    
DOI: 10.1152/ajpregu.00171.2011     Document Type: Article
Times cited : (15)

References (31)
  • 1
    • 0023547663 scopus 로고
    • Rate of glucose fall does not affect counterregulatory hormone responses to hypoglycemia in normal and diabetic humans
    • Amiel SA, Simonson DC, Tamborlane WV, DeFronzo RA, Sherwin RS. Rate of glucose fall does not affect counterregulatory hormone responses to hypoglycemia in normal and diabetic humans. Diabetes 36: 518-522, 1987.
    • (1987) Diabetes , vol.36 , pp. 518-522
    • Amiel, S.A.1    Simonson, D.C.2    Tamborlane, W.V.3    Defronzo, R.A.4    Sherwin, R.S.5
  • 3
    • 0031038124 scopus 로고    scopus 로고
    • Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats
    • Borg MA, Sherwin RS, Borg WP, Tamborlane WV, Shulman GI. Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats. J Clin Invest 99: 361-365, 1997.
    • (1997) J Clin Invest , vol.99 , pp. 361-365
    • Borg, M.A.1    Sherwin, R.S.2    Borg, W.P.3    Tamborlane, W.V.4    Shulman, G.I.5
  • 4
    • 0028296222 scopus 로고
    • Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia
    • Borg WP, During MJ, Sherwin RS, Borg MA, Brines ML, Shulman GI. Ventromedial hypothalamic lesions in rats suppress counterregulatory responses to hypoglycemia. J Clin Invest 93: 1677-1682, 1994.
    • (1994) J Clin Invest , vol.93 , pp. 1677-1682
    • Borg, W.P.1    During, M.J.2    Sherwin, R.S.3    Borg, M.A.4    Brines, M.L.5    Shulman, G.I.6
  • 6
    • 0345074150 scopus 로고    scopus 로고
    • Effect of hypoglycemia on brain glycogen metabolism in vivo
    • Choi IY, Seaquist ER, Gruetter R. Effect of hypoglycemia on brain glycogen metabolism in vivo. J Neurosci Res 72: 25-32, 2003.
    • (2003) J Neurosci Res , vol.72 , pp. 25-32
    • Choi, I.Y.1    Seaquist, E.R.2    Gruetter, R.3
  • 8
    • 0242268888 scopus 로고    scopus 로고
    • Extracellular glucose in rat ventromedial hypothalamus during acute and recurrent hypoglycemia
    • de Vries MG, Arseneau LM, Lawson ME, Beverly JL. Extracellular glucose in rat ventromedial hypothalamus during acute and recurrent hypoglycemia. Diabetes 52: 2767-2773, 2003.
    • (2003) Diabetes , vol.52 , pp. 2767-2773
    • de Vries, M.G.1    Arseneau, L.M.2    Lawson, M.E.3    Beverly, J.L.4
  • 9
    • 1942487413 scopus 로고    scopus 로고
    • Dissociation of hypothalamic noradrenergic activity and sympathoadrenal responses to recurrent hypoglycemia
    • de Vries MG, Lawson MA, Beverly JL. Dissociation of hypothalamic noradrenergic activity and sympathoadrenal responses to recurrent hypoglycemia. Am J Physiol Regul Integr Comp Physiol 286: R910-R915, 2004.
    • (2004) Am J Physiol Regul Integr Comp Physiol , vol.286
    • de Vries, M.G.1    Lawson, M.A.2    Beverly, J.L.3
  • 10
    • 25844498847 scopus 로고    scopus 로고
    • Hypoglycemia-induced noradrenergic activation in the VMH is a result of decreased ambient glucose
    • de Vries MG, Lawson MA, Beverly JL. Hypoglycemia-induced noradrenergic activation in the VMH is a result of decreased ambient glucose. Am J Physiol Regul Integr Comp Physiol 289: R977-R981, 2005.
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.289
    • de Vries, M.G.1    Lawson, M.A.2    Beverly, J.L.3
  • 11
    • 0026027379 scopus 로고
    • Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia
    • Donovan CM, Halter JB, Bergman RN. Importance of hepatic glucoreceptors in sympathoadrenal response to hypoglycemia. Diabetes 40: 155-158, 1991.
    • (1991) Diabetes , vol.40 , pp. 155-158
    • Donovan, C.M.1    Halter, J.B.2    Bergman, R.N.3
  • 13
    • 0033378037 scopus 로고    scopus 로고
    • The role of astrocytes and noradrenaline in neuronal glucose metabolism
    • Fillenz Lowry Boutelle, Fray. The role of astrocytes and noradrenaline in neuronal glucose metabolism. Acta Physiol Scand 167: 275-284, 1999.
    • (1999) Acta Physiol Scand , vol.167 , pp. 275-284
    • Lowry, F.L.1
  • 14
    • 33748297796 scopus 로고    scopus 로고
    • Ibotenic acid lesions reduce noradrenergic activation in ventromedial hypothalamus during hypoglycemia
    • Fugo KR, Lawson MA, Lee Beverly J. Ibotenic acid lesions reduce noradrenergic activation in ventromedial hypothalamus during hypoglycemia. Brain Res 1111: 105-110, 2006.
    • (2006) Brain Res , vol.1111 , pp. 105-110
    • Fugo, K.R.1    Lawson, M.A.2    Lee Beverly, J.3
  • 15
    • 0026035949 scopus 로고
    • Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans
    • Heller SR, Cryer PE. Reduced neuroendocrine and symptomatic responses to subsequent hypoglycemia after 1 episode of hypoglycemia in nondiabetic humans. Diabetes 40: 223-226, 1991.
    • (1991) Diabetes , vol.40 , pp. 223-226
    • Heller, S.R.1    Cryer, P.E.2
  • 16
    • 0033957338 scopus 로고    scopus 로고
    • Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia
    • Hevener AL, Bergman RN, Donovan CM. Portal vein afferents are critical for the sympathoadrenal response to hypoglycemia. Diabetes 49: 8-12, 2000.
    • (2000) Diabetes , vol.49 , pp. 8-12
    • Hevener, A.L.1    Bergman, R.N.2    Donovan, C.M.3
  • 18
    • 0842309997 scopus 로고    scopus 로고
    • Effect of recurrent hypoglycemia on spatial cognition and cognitive metabolism in normal and diabetic rats
    • McNay EC, Sherwin RS. Effect of recurrent hypoglycemia on spatial cognition and cognitive metabolism in normal and diabetic rats. Diabetes 53: 418-425, 2004.
    • (2004) Diabetes , vol.53 , pp. 418-425
    • McNay, E.C.1    Sherwin, R.S.2
  • 21
    • 0036065157 scopus 로고    scopus 로고
    • Glucose-sensing neurons: Are they physiologically relevant?
    • Routh VH. Glucose-sensing neurons: are they physiologically relevant? Physiol Behav 76: 403-413, 2002.
    • (2002) Physiol Behav , vol.76 , pp. 403-413
    • Routh, V.H.1
  • 22
    • 48449097409 scopus 로고    scopus 로고
    • The locus for hypoglycemic detection shifts with the rate of fall in glycemia: The role of portal-superior mesenteric vein glucose sensing
    • Saberi M, Bohland M, Donovan CM. The locus for hypoglycemic detection shifts with the rate of fall in glycemia: the role of portal-superior mesenteric vein glucose sensing. Diabetes 57: 1380-1386, 2008.
    • (2008) Diabetes , vol.57 , pp. 1380-1386
    • Saberi, M.1    Bohland, M.2    Donovan, C.M.3
  • 24
    • 0035432605 scopus 로고    scopus 로고
    • Blood-to-brain glucose transport, cerebral glucose metabolism, and cerebral blood flow are not increased after hypoglycemia
    • Segel SA, Fanelli CG, Dence CS, Markham J, Videen TO, Paramore DS, Powers WJ, Cryer PE. Blood-to-brain glucose transport, cerebral glucose metabolism, and cerebral blood flow are not increased after hypoglycemia. Diabetes 50: 1911-1917, 2001.
    • (2001) Diabetes , vol.50 , pp. 1911-1917
    • Segel, S.A.1    Fanelli, C.G.2    Dence, C.S.3    Markham, J.4    Videen, T.O.5    Paramore, D.S.6    Powers, W.J.7    Cryer, P.E.8
  • 25
    • 0020530053 scopus 로고
    • Functional correlations between lateral hypothalamic glucose-sensitive neurons and hepatic portal glucose-sensitive units in rat
    • Shimizu N, Oomura Y, Novin D, Grijalva CV, Cooper PH. Functional correlations between lateral hypothalamic glucose-sensitive neurons and hepatic portal glucose-sensitive units in rat. Brain Res 265: 49-54, 1983.
    • (1983) Brain Res , vol.265 , pp. 49-54
    • Shimizu, N.1    Oomura, Y.2    Novin, D.3    Grijalva, C.V.4    Cooper, P.H.5
  • 27
    • 0026464807 scopus 로고
    • Suppression of central noradrenergic neuronal activity inhibits hyperglycemia
    • Smythe GA, Edwards SR. Suppression of central noradrenergic neuronal activity inhibits hyperglycemia. Am J Physiol Endocrinol Metab 263: E823-E827, 1992.
    • (1992) Am J Physiol Endocrinol Metab , vol.263
    • Smythe, G.A.1    Edwards, S.R.2
  • 29
    • 0035650534 scopus 로고    scopus 로고
    • Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus
    • Song Z, Levin BE, McArdle JJ, Bakhos N, Routh VH. Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus. Diabetes 50: 2673-2681, 2001.
    • (2001) Diabetes , vol.50 , pp. 2673-2681
    • Song, Z.1    Levin, B.E.2    McArdle, J.J.3    Bakhos, N.4    Routh, V.H.5
  • 30
    • 33751192694 scopus 로고    scopus 로고
    • Recurrent hypoglycemia reduces the glucose sensitivity of glucose-inhibited neurons in the ventromedial hypothalamus nucleus
    • Song Z, Routh VH. Recurrent hypoglycemia reduces the glucose sensitivity of glucose-inhibited neurons in the ventromedial hypothalamus nucleus. Am J Physiol Regul Integr Comp Physiol 291: R1283-R1287, 2006.
    • (2006) Am J Physiol Regul Integr Comp Physiol , vol.291
    • Song, Z.1    Routh, V.H.2
  • 31
    • 0024269669 scopus 로고
    • Hypothalamic food intake regulating areas are involved in the homeostasis of blood glucose and plasma FFA levels
    • Steffens AB, Scheurink AJ, Luiten PG, Bohus B. Hypothalamic food intake regulating areas are involved in the homeostasis of blood glucose and plasma FFA levels. Physiol Behav 44: 581-589, 1988.
    • (1988) Physiol Behav , vol.44 , pp. 581-589
    • Steffens, A.B.1    Scheurink, A.J.2    Luiten, P.G.3    Bohus, B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.