Negative epistasis between α + thalassaemia and sickle cell trait can explain interpopulation variation in South Asia

Evolution

Volumn 65, Issue 12, 2011, Pages 3625-3632

  Penman, Bridget S ^a   Habib, Saman ^b   Kanchan, Kanika ^b   Gupta, Sunetra ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

Epistasis; Human evolution; Malaria; Population genetics; Sickle cell; South Asia

Indexed keywords

BLOOD SYSTEM DISORDER; DISEASE INCIDENCE; DISEASE PREVALENCE; EPISTASIS; HEMOGLOBIN; HERITABILITY; HUMAN EVOLUTION; INTERPOPULATION VARIATION; MALARIA; POPULATION GENETICS;

ALPHA THALASSEMIA; ARTICLE; ASIA; DISEASE RESISTANCE; EVOLUTION; GENETIC EPISTASIS; GENETIC SELECTION; GENETICS; HUMAN; MALARIA; SICKLE CELL TRAIT;

ALPHA-THALASSEMIA; ASIA; BIOLOGICAL EVOLUTION; DISEASE RESISTANCE; EPISTASIS, GENETIC; HUMANS; MALARIA; SELECTION, GENETIC; SICKLE CELL TRAIT;

GHANA; KENYA;

EID: 82755182805     PISSN: 00143820     EISSN: 15585646     Source Type: Journal    
DOI: 10.1111/j.1558-5646.2011.01408.x     Document Type: Article

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