메뉴 건너뛰기




Volumn 22, Issue 1, 2012, Pages 39-43

Toxicity of local anesthetic drugs: A pediatric perspective

Author keywords

adverse events; age; child; complications; drugs; lipid rescue; local anesthetics

Indexed keywords

ADRENALIN; BUPIVACAINE; LEVOBULIVACAINE; LIDOCAINE; LOCAL ANESTHETIC AGENT; ROPIVACAINE; SODIUM CHANNEL; UNCLASSIFIED DRUG;

EID: 82655172575     PISSN: 11555645     EISSN: 14609592     Source Type: Journal    
DOI: 10.1111/j.1460-9592.2011.03631.x     Document Type: Review
Times cited : (49)

References (34)
  • 1
    • 0022647879 scopus 로고
    • Cardiotoxicity of local anaesthetic agents
    • Reiz S, Nath S,. Cardiotoxicity of local anaesthetic agents. Br J Anaesth 1986; 58: 736-746. (Pubitemid 16098078)
    • (1986) British Journal of Anaesthesia , vol.58 , Issue.7 , pp. 736-746
    • Reiz, S.1    Nath, S.2
  • 2
    • 0034760364 scopus 로고    scopus 로고
    • Systemic toxicity of levobupivacaine, bupivacaine, and ropivacaine during continuous intravenous infusion to nonpregnant and pregnant Ewes
    • Santos AC, DeArmas PI,. Systemic toxicity of levobupivacaine, bupivacaine, and ropivacaine during continuous intravenous infusion to nonpregnant and pregnant ewes. Anesthesiology 2001; 95: 1256-1264. (Pubitemid 33043244)
    • (2001) Anesthesiology , vol.95 , Issue.5 , pp. 1256-1264
    • Santos, A.C.1    DeArmas, P.I.2
  • 3
    • 0031742311 scopus 로고    scopus 로고
    • Epidural pain relief in labour: Potencies of levobupivacaine and racemic bupivacaine
    • Lyons G, Columb M, Wilson RC, et al. Epidural pain relief in labour: potencies of levobupivacaine and racemic bupivacaine. Br J Anaesth 1998; 81: 899-901. (Pubitemid 28561323)
    • (1998) British Journal of Anaesthesia , vol.81 , Issue.6 , pp. 899-901
    • Lyons, G.1    Columb, M.2    Wilson, R.C.3    Johnson, R.V.4
  • 4
    • 0032944027 scopus 로고    scopus 로고
    • Relative analgesic potencies of ropivacaine and bupivacaine for epidural analgesia in labor: Implications for therapeutic indexes
    • DOI 10.1097/00000542-199904000-00003
    • Polley LS, Columb MO, Naughton NN, et al. Relative analgesic potencies of ropivacaine and bupivacaine for epidural analgesia in labor: implications for therapeutic indexes. Anesthesiology 1999; 90: 944-950. (Pubitemid 29159747)
    • (1999) Anesthesiology , vol.90 , Issue.4 , pp. 944-950
    • Polley, L.S.1    Columb, M.O.2    Naughton, N.N.3    Wagner, D.S.4    Van De Ven, C.J.M.5
  • 5
    • 0028817743 scopus 로고
    • Stereoselective block of cardiac sodium channels by bupivacaine in guinea pig ventricular myocytes
    • Valenzuela C, Snyders DJ, Bennett PB, et al. Stereoselective block of cardiac sodium channels by bupivacaine in guinea pig ventricular myocytes. Circulation 1995; 92: 3014-3024.
    • (1995) Circulation , vol.92 , pp. 3014-3024
    • Valenzuela, C.1    Snyders, D.J.2    Bennett, P.B.3
  • 6
    • 0026704465 scopus 로고
    • Seizures occurring in pediatric patients receiving continuous infusion of bupivacaine
    • Agarwal R, Gutlove DP, Lockhart CH,. Seizures occurring in pediatric patients receiving continuous infusion of bupivacaine. Anesth Analg 1992; 75: 284-286.
    • (1992) Anesth Analg , vol.75 , pp. 284-286
    • Agarwal, R.1    Gutlove, D.P.2    Lockhart, C.H.3
  • 7
    • 0026742062 scopus 로고
    • Bupivacaine toxicity secondary to continuous caudal epidural infusion in children
    • McCloskey JJ, Haun SE, Deshpande JK,. Bupivacaine toxicity secondary to continuous caudal epidural infusion in children. Anesth Analg 1992; 75: 287-290.
    • (1992) Anesth Analg , vol.75 , pp. 287-290
    • McCloskey, J.J.1    Haun, S.E.2    Deshpande, J.K.3
  • 8
    • 0028331370 scopus 로고
    • Bupivacaine-induced cardiac toxicity in neonates: Successful treatment with intravenous phenytoin
    • Maxwell LG, Martin LD, Yaster M,. Bupivacaine-induced cardiac toxicity in neonates: successful treatment with intravenous phenytoin. Anesthesiology 1994; 80: 682-686. (Pubitemid 24097702)
    • (1994) Anesthesiology , vol.80 , Issue.3 , pp. 682-686
    • Maxwell, L.G.1    Martin, L.D.2    Yaster, M.3
  • 9
    • 0027160264 scopus 로고
    • Toxicity of local anesthetics in infants and children
    • Berde CB,. Toxicity of local anesthetics in infants and children. J Pediatr 1993; 122: S14-S20. (Pubitemid 23132077)
    • (1993) Journal of Pediatrics , vol.122 , Issue.SUPPL.
    • Berde, C.B.1
  • 11
    • 0034947046 scopus 로고    scopus 로고
    • Pharmacokinetics and analgesic effect of ropivacaine following ilioinguinal/iliohypogastric nerve block in children
    • DOI 10.1046/j.1460-9592.2001.00691.x
    • Dalens B, Ecoffey C, Joly A, et al. Pharmacokinetics and analgesic effect of ropivacaine following ilioinguinal/iliohypogastric nerve block in children. Paediatr Anaesth 2001; 11: 415-420. (Pubitemid 32635318)
    • (2001) Paediatric Anaesthesia , vol.11 , Issue.4 , pp. 415-420
    • Dalens, B.1    Ecoffey, C.2    Joly, A.3    Giaufre, E.4    Gustafsson, U.5    Huledal, G.6    Larsson, L.E.7
  • 14
    • 0022647189 scopus 로고
    • Pharmacokinetics of local anaesthetics
    • Tucker GT,. Pharmacokinetics of local anaesthetics. Br J Anaesth 1986; 58: 717-731. (Pubitemid 16098076)
    • (1986) British Journal of Anaesthesia , vol.58 , Issue.7 , pp. 717-731
    • Tucker, G.T.1
  • 15
    • 0442291790 scopus 로고    scopus 로고
    • Pharmacokinetics of Local Anaesthetics in Infants and Children
    • DOI 10.2165/00003088-200443010-00002
    • Mazoit JX, Dalens BJ,. Pharmacokinetics of local anaesthetics in infants and children. Clin Pharmacokinet 2004; 43: 17-32. (Pubitemid 38186931)
    • (2004) Clinical Pharmacokinetics , vol.43 , Issue.1 , pp. 17-32
    • Mazoit, J.-X.1    Dalens, B.J.2
  • 16
    • 0034943235 scopus 로고    scopus 로고
    • Pharmacokinetics of bupivacaine after continuous epidural infusion in infants with and without biliary atresia
    • Meunier JF, Goujard E, Dubousset AM, et al. Pharmacokinetics of bupivacaine after continuous epidural infusion in infants with and without biliary atresia. Anesthesiology 2001; 95: 87-95. (Pubitemid 32623001)
    • (2001) Anesthesiology , vol.95 , Issue.1 , pp. 87-95
    • Meunier, J.-F.1    Goujard, E.2    Dubousset, A.-M.3    Samii, K.4    Mazoit, J.X.5
  • 17
    • 0025175012 scopus 로고
    • Efficacy of an epidural test dose in children anesthetized with halothane
    • Desparmet J, Mateo J, Ecoffey C, et al. Efficacy of an epidural test dose in children anesthetized with halothane. Anesthesiology 1990; 72: 249-251. (Pubitemid 20057989)
    • (1990) Anesthesiology , vol.72 , Issue.2 , pp. 249-251
    • Desparmet, J.1    Mateo, J.2    Ecoffey, C.3    Mazoit, X.4
  • 18
    • 0031960886 scopus 로고    scopus 로고
    • Simulation of an epidural test dose with intravenous epinephrine in sevoflurane-anesthetized children
    • Tanaka M, Nishikawa T,. Simulation of an epidural test dose with intravenous epinephrine in sevoflurane-anesthetized children. Anesth Analg 1998; 86: 952-957.
    • (1998) Anesth Analg , vol.86 , pp. 952-957
    • Tanaka, M.1    Nishikawa, T.2
  • 19
    • 0032871089 scopus 로고    scopus 로고
    • The efficacy of a simulated intravascular test dose in sevoflurane- anesthetized children: A dose-response study
    • DOI 10.1097/00000539-199909000-00016
    • Tanaka M, Nishikawa T,. The efficacy of a simulated intravascular test dose in sevoflurane-anesthetized children: a dose-response study. Anesth Analg 1999; 89: 632-637. (Pubitemid 29409809)
    • (1999) Anesthesia and Analgesia , vol.89 , Issue.3 , pp. 632-637
    • Tanaka, M.1    Nishikawa, T.2
  • 21
    • 74049085377 scopus 로고    scopus 로고
    • Positive intravascular test dose criteria in children during total intravenous anesthesia with propofol and remifentanil are different than during inhaled anesthesia
    • Polaner DM, Zuk J, Luong K, et al. Positive intravascular test dose criteria in children during total intravenous anesthesia with propofol and remifentanil are different than during inhaled anesthesia. Anesth Analg 2010; 110: 41-45.
    • (2010) Anesth Analg , vol.110 , pp. 41-45
    • Polaner, D.M.1    Zuk, J.2    Luong, K.3
  • 22
    • 0032037916 scopus 로고    scopus 로고
    • Early signs of toxicity and "subtoxic" conditions in infant monitoring. Bupivacaine plasma levels following caudal anesthesia
    • Breschan C, Hellstrand E, Likar R, et al. Early signs of toxicity and "subtoxic" conditions in infant monitoring. Bupivacaine plasma levels following caudal anesthesia. Anaesthesist 1998; 47: 290-294.
    • (1998) Anaesthesist , vol.47 , pp. 290-294
    • Breschan, C.1    Hellstrand, E.2    Likar, R.3
  • 23
    • 77952404394 scopus 로고    scopus 로고
    • Treatment of local anesthetic systemic toxicity (LAST)
    • Weinberg GL,. Treatment of local anesthetic systemic toxicity (LAST). Reg Anesth Pain Med 2010; 35: 188-193.
    • (2010) Reg Anesth Pain Med , vol.35 , pp. 188-193
    • Weinberg, G.L.1
  • 24
    • 0037686712 scopus 로고    scopus 로고
    • Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity
    • DOI 10.1053/rapm.2003.50041
    • Weinberg G, Ripper R, Feinstein DL, et al. Lipid emulsion infusion rescues dogs from bupivacaine-induced cardiac toxicity. Reg Anesth Pain Med 2003; 28: 198-202. (Pubitemid 36618312)
    • (2003) Regional Anesthesia and Pain Medicine , vol.28 , Issue.3 , pp. 198-202
    • Weinberg, G.1    Ripper, R.2    Feinstein, D.L.3    Hoffman, W.4
  • 25
    • 33746864495 scopus 로고    scopus 로고
    • Lipid infusion resuscitation for local anesthetic toxicity: Proof of clinical efficacy
    • DOI 10.1097/00000542-200607000-00005, PII 0000054220060700000005
    • Weinberg G,. Lipid infusion resuscitation for local anesthetic toxicity: proof of clinical efficacy. Anesthesiology 2006; 105: 7-8. (Pubitemid 44305184)
    • (2006) Anesthesiology , vol.105 , Issue.1 , pp. 7-8
    • Weinberg, G.1
  • 26
    • 79551628916 scopus 로고    scopus 로고
    • Lipid resuscitation: A life-saving antidote for local anesthetic toxicity
    • Bern S, Akpa BS, Kuo I, et al. Lipid resuscitation: a life-saving antidote for local anesthetic toxicity. Curr Pharm Biotechnol 2011; 12: 313-319.
    • (2011) Curr Pharm Biotechnol , vol.12 , pp. 313-319
    • Bern, S.1    Akpa, B.S.2    Kuo, I.3
  • 27
    • 78049428899 scopus 로고    scopus 로고
    • Partitioning effect in lipid resuscitation: Further evidence for the lipid sink
    • Weinberg G, Lin B, Zheng S, et al. Partitioning effect in lipid resuscitation: further evidence for the lipid sink. Crit Care Med 2010; 38: 2268-2269.
    • (2010) Crit Care Med , vol.38 , pp. 2268-2269
    • Weinberg, G.1    Lin, B.2    Zheng, S.3
  • 28
    • 69549120141 scopus 로고    scopus 로고
    • Epinephrine impairs lipid resuscitation from bupivacaine overdose: A threshold effect
    • Hiller DB, Gregorio GD, Ripper R, et al. Epinephrine impairs lipid resuscitation from bupivacaine overdose: a threshold effect. Anesthesiology 2009; 111: 498-505.
    • (2009) Anesthesiology , vol.111 , pp. 498-505
    • Hiller, D.B.1    Gregorio, G.D.2    Ripper, R.3
  • 29
    • 70349582312 scopus 로고    scopus 로고
    • Lipid emulsion improves recovery from bupivacaine-induced cardiac arrest, but not from ropivacaine- or mepivacaine-induced cardiac arrest
    • Zausig YA, Zink W, Keil M, et al. Lipid emulsion improves recovery from bupivacaine-induced cardiac arrest, but not from ropivacaine- or mepivacaine-induced cardiac arrest. Anesth Analg 2009; 109: 1323-1326.
    • (2009) Anesth Analg , vol.109 , pp. 1323-1326
    • Zausig, Y.A.1    Zink, W.2    Keil, M.3
  • 30
    • 42449100412 scopus 로고    scopus 로고
    • Successful resuscitation after ropivacaine and lidocaine-induced ventricular arrhythmia following posterior lumbar plexus block in a child
    • DOI 10.1213/01.ane.0000286176.55971.f0, PII 0000053920080500000041
    • Ludot H, Tharin JY, Belouadah M, et al. Successful resuscitation after ropivacaine and lidocaine-induced ventricular arrhythmia following posterior lumbar plexus block in a child. Anesth Analg 2008; 106: 1572-1574. (Pubitemid 351571095)
    • (2008) Anesthesia and Analgesia , vol.106 , Issue.5 , pp. 1572-1574
    • Ludot, H.1    Tharin, J.-Y.2    Belouadah, M.3    Mazoit, J.-X.4    Malinovsky, J.-M.5
  • 31
    • 79954463946 scopus 로고    scopus 로고
    • Intravenous lipid emulsion: Why wait to save a life?
    • Weinberg GL,. Intravenous lipid emulsion: why wait to save a life? Emerg Med Australas 2011; 23: 113-115.
    • (2011) Emerg Med Australas , vol.23 , pp. 113-115
    • Weinberg, G.L.1
  • 33
    • 3242876818 scopus 로고    scopus 로고
    • Local anesthetic myotoxicity
    • DOI 10.1016/j.rapm.2004.02.008, PII S1098733904000719
    • Zink W, Graf BM,. Local anesthetic myotoxicity. Reg Anesth Pain Med 2004; 29: 333-340. (Pubitemid 39055660)
    • (2004) Regional Anesthesia and Pain Medicine , vol.29 , Issue.4 , pp. 333-340
    • Zink, W.1    Graf, B.M.2
  • 34
    • 50649101153 scopus 로고    scopus 로고
    • Intramuscular beta2-agonist administration enhances early regeneration and functional repair in rat skeletal muscle after myotoxic injury
    • Ryall JG, Schertzer JD, Alabakis TM, et al. Intramuscular beta2-agonist administration enhances early regeneration and functional repair in rat skeletal muscle after myotoxic injury. J Appl Physiol 2008; 105: 165-172.
    • (2008) J Appl Physiol , vol.105 , pp. 165-172
    • Ryall, J.G.1    Schertzer, J.D.2    Alabakis, T.M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.