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Volumn 119, Issue 3, 2011, Pages 179-186

Quantitative assessment of time dependent drug-use trends by the analysis of drugs and related metabolites in raw sewage

Author keywords

Cocaine; Drug epidemiology; Methamphetamine; Sewage analysis

Indexed keywords

CETIRIZINE; COCAINE; METHAMPHETAMINE; METOPROLOL;

EID: 82555189788     PISSN: 03768716     EISSN: 18790046     Source Type: Journal    
DOI: 10.1016/j.drugalcdep.2011.06.007     Document Type: Article
Times cited : (54)

References (62)
  • 1
    • 0022351370 scopus 로고
    • The urinary excretion of cocaine and metabolites in humans: a kinetic analysis of published data
    • Ambre J. The urinary excretion of cocaine and metabolites in humans: a kinetic analysis of published data. J. Anal. Toxicol. 1985, 9:241-245.
    • (1985) J. Anal. Toxicol. , vol.9 , pp. 241-245
    • Ambre, J.1
  • 2
    • 0021338468 scopus 로고
    • Urinary excretion of ecgonine methyl ester, a major metabolite of cocaine in humans
    • Ambre J. Urinary excretion of ecgonine methyl ester, a major metabolite of cocaine in humans. J. Anal. Toxicol. 1984, 8:23-25.
    • (1984) J. Anal. Toxicol. , vol.8 , pp. 23-25
    • Ambre, J.1
  • 3
    • 0023763293 scopus 로고
    • Urinary excretion of cocaine, benzoylecgonine, and ecgonine methyl ester in humans
    • Ambre J., Ruo T., Nelson J. Urinary excretion of cocaine, benzoylecgonine, and ecgonine methyl ester in humans. J. Anal. Toxicol. 1988, 12:301-306.
    • (1988) J. Anal. Toxicol. , vol.12 , pp. 301-306
    • Ambre, J.1    Ruo, T.2    Nelson, J.3
  • 4
    • 70349850740 scopus 로고    scopus 로고
    • The spatial epidemiology of cocaine, methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) use: a demonstration using a population measure of community drug load derived from municipal wastewater
    • Banta-Green C.J., Field J.A., Chiaia A.C., Sudakin D.L., Power L., de Montigny L. The spatial epidemiology of cocaine, methamphetamine and 3,4-methylenedioxymethamphetamine (MDMA) use: a demonstration using a population measure of community drug load derived from municipal wastewater. Addiction 2009, 104:1874-1880.
    • (2009) Addiction , vol.104 , pp. 1874-1880
    • Banta-Green, C.J.1    Field, J.A.2    Chiaia, A.C.3    Sudakin, D.L.4    Power, L.5    de Montigny, L.6
  • 5
    • 67549088432 scopus 로고    scopus 로고
    • Validity of the self-report on drug use by university students: correspondence between self-reported use and use detected in urine
    • Basurto F.Z., Montes J.M.G., Cubos P.F., Santed F.S., Rios F.L., Moreno A.M. Validity of the self-report on drug use by university students: correspondence between self-reported use and use detected in urine. Psicothema 2009, 21:213-219.
    • (2009) Psicothema , vol.21 , pp. 213-219
    • Basurto, F.Z.1    Montes, J.M.G.2    Cubos, P.F.3    Santed, F.S.4    Rios, F.L.5    Moreno, A.M.6
  • 6
    • 34347373034 scopus 로고    scopus 로고
    • Using environmental analytical data to estimate levels of community consumption of illicit drugs and abused pharmaceuticals
    • Bones J., Thomas K.V., Paull B. Using environmental analytical data to estimate levels of community consumption of illicit drugs and abused pharmaceuticals. J. Environ. Monit. 2007, 9:701.
    • (2007) J. Environ. Monit. , vol.9 , pp. 701
    • Bones, J.1    Thomas, K.V.2    Paull, B.3
  • 7
    • 0036909104 scopus 로고    scopus 로고
    • Cannabis use: consistency and validity of self-report, on-site urine testing and laboratory testing
    • Buchan B.J., Dennis M.L., Tims F.M., Diamond G.S. Cannabis use: consistency and validity of self-report, on-site urine testing and laboratory testing. Addiction 2002, 9:98-108.
    • (2002) Addiction , vol.9 , pp. 98-108
    • Buchan, B.J.1    Dennis, M.L.2    Tims, F.M.3    Diamond, G.S.4
  • 8
    • 33845528593 scopus 로고    scopus 로고
    • Identification and measurement of illicit drugs and their metabolites in urban wastewater by liquid chromatography-tandem mass spectrometry
    • Castiglioni S., Zuccato E., Crisci E., Chiabrando C., Fanelli R., Bagnati R. Identification and measurement of illicit drugs and their metabolites in urban wastewater by liquid chromatography-tandem mass spectrometry. Anal. Chem. 2006, 78:8421-8429.
    • (2006) Anal. Chem. , vol.78 , pp. 8421-8429
    • Castiglioni, S.1    Zuccato, E.2    Crisci, E.3    Chiabrando, C.4    Fanelli, R.5    Bagnati, R.6
  • 10
    • 0037437645 scopus 로고    scopus 로고
    • Enantioselective determination of metoprolol acidic metabolite in plasma and urine using liquid chromatography chiral columns: applications to pharmacokinetics
    • Cerqueira P.M., Boralli V.B., Coelho E.B., Lopes N.P., Guimaraes L.F.L., Bonato P.S., Lanchote V.L. Enantioselective determination of metoprolol acidic metabolite in plasma and urine using liquid chromatography chiral columns: applications to pharmacokinetics. J. Chromatogr. B. 2003, 783:433-441.
    • (2003) J. Chromatogr. B. , vol.783 , pp. 433-441
    • Cerqueira, P.M.1    Boralli, V.B.2    Coelho, E.B.3    Lopes, N.P.4    Guimaraes, L.F.L.5    Bonato, P.S.6    Lanchote, V.L.7
  • 11
    • 0036399169 scopus 로고    scopus 로고
    • Patterns of methamphetamine abuse and their consequences
    • Cho A.K., Melega W.P. Patterns of methamphetamine abuse and their consequences. J. Addict. Dis. 2002, 21:21-34.
    • (2002) J. Addict. Dis. , vol.21 , pp. 21-34
    • Cho, A.K.1    Melega, W.P.2
  • 12
    • 0029145959 scopus 로고
    • Pharmacokinetics and pharmacodynamics of cocaine
    • Cone E.J. Pharmacokinetics and pharmacodynamics of cocaine. J. Anal. Toxicol. 1995, 19:459-478.
    • (1995) J. Anal. Toxicol. , vol.19 , pp. 459-478
    • Cone, E.J.1
  • 13
    • 0032420755 scopus 로고    scopus 로고
    • Recent discoveries in pharmacokinetics of drugs of abuse
    • Cone E.J. Recent discoveries in pharmacokinetics of drugs of abuse. Toxicol. Lett. 1998, 102:97-101.
    • (1998) Toxicol. Lett. , vol.102 , pp. 97-101
    • Cone, E.J.1
  • 14
    • 0141682620 scopus 로고    scopus 로고
    • Urine testing for cocaine abuse: metabolic and excretion patterns following different routes of administration and methods for detection of false-negative results
    • Cone E.J., Sampson-Cone A., Darwin W., Huestis M., Oyler J. Urine testing for cocaine abuse: metabolic and excretion patterns following different routes of administration and methods for detection of false-negative results. J. Anal. Toxicol. 2003, 27:386-401.
    • (2003) J. Anal. Toxicol. , vol.27 , pp. 386-401
    • Cone, E.J.1    Sampson-Cone, A.2    Darwin, W.3    Huestis, M.4    Oyler, J.5
  • 15
    • 0031657546 scopus 로고    scopus 로고
    • Cocaine metabolism and urinary excretion after different routes of administration
    • Cone E.J., Tsadik A., Oyler J., Darwin W.D. Cocaine metabolism and urinary excretion after different routes of administration. Ther. Drug Monit. 1998, 20:556-560.
    • (1998) Ther. Drug Monit. , vol.20 , pp. 556-560
    • Cone, E.J.1    Tsadik, A.2    Oyler, J.3    Darwin, W.D.4
  • 17
    • 84857503254 scopus 로고    scopus 로고
    • European Monitoring Centre for Drugs and Drug Addiction. Analysis of the Drug Situation in Europe: Statistical Bulletin 2009. Available from:
    • European Monitoring Centre for Drugs and Drug Addiction, 2009. Analysis of the Drug Situation in Europe: Statistical Bulletin 2009. Available from: http://www.emcdda.europa.eu/stats09.
    • (2009)
  • 18
    • 84857508024 scopus 로고    scopus 로고
    • European Monitoring Centre for Drugs and Drug Addiction. The state of the drugs problem in Europe. EMCDDA Annual Report. Available from:
    • European Monitoring Centre for Drugs and Drug Addiction, 2010. The state of the drugs problem in Europe. EMCDDA Annual Report. Available from: http://www.emcdda.europa.eu/publications/annual-report/2010.
    • (2010)
  • 19
    • 0036735598 scopus 로고    scopus 로고
    • Cannabis use and psychosocial adjustment in adolescence and young adulthood
    • Fergusson D.M.L., Horwood J., Swain-Campbell N. Cannabis use and psychosocial adjustment in adolescence and young adulthood. Addiction 2002, 97:1123-1135. 10.1046/j.1360-0443.2002.00103.x.
    • (2002) Addiction , vol.97 , pp. 1123-1135
    • Fergusson, D.M.L.1    Horwood, J.2    Swain-Campbell, N.3
  • 20
    • 44349155325 scopus 로고    scopus 로고
    • Analysis of cocaine and its principal metabolites in waste and surface water using solid-phase extraction and liquid chromatography-ion trap tandem mass spectrometry
    • Gheorghe A., Nuijs A., Pecceu B., Bervoets L., Jorens P.G., Blust R., Neels H., Covaci A. Analysis of cocaine and its principal metabolites in waste and surface water using solid-phase extraction and liquid chromatography-ion trap tandem mass spectrometry. Anal. Bioanal. Chem. 2008, 391:1309-1319.
    • (2008) Anal. Bioanal. Chem. , vol.391 , pp. 1309-1319
    • Gheorghe, A.1    Nuijs, A.2    Pecceu, B.3    Bervoets, L.4    Jorens, P.G.5    Blust, R.6    Neels, H.7    Covaci, A.8
  • 21
    • 0033990589 scopus 로고    scopus 로고
    • Reductions in acquisitive crime and drug use after treatment of addiction problems: 1-year follow-up outcomes
    • Gossop M., Marsden J., Stewart D., Rolfe A. Reductions in acquisitive crime and drug use after treatment of addiction problems: 1-year follow-up outcomes. Drug Alcohol Depend. 2000, 58:165-172. 10.1016/S0376-8716(99)00077-0.
    • (2000) Drug Alcohol Depend. , vol.58 , pp. 165-172
    • Gossop, M.1    Marsden, J.2    Stewart, D.3    Rolfe, A.4
  • 23
    • 0242551164 scopus 로고    scopus 로고
    • The pharmacology of cocaethylene in humans following cocaine and ethanol administration
    • Harris D.S., Everhart E.T., Mendelson J., Jones R.T. The pharmacology of cocaethylene in humans following cocaine and ethanol administration. Drug Alcohol Depend. 2003, 72:169-182.
    • (2003) Drug Alcohol Depend. , vol.72 , pp. 169-182
    • Harris, D.S.1    Everhart, E.T.2    Mendelson, J.3    Jones, R.T.4
  • 24
    • 39849111051 scopus 로고    scopus 로고
    • Inconsistencies in self-reported drug use by adolescents in substance abuse treatment: implications for outcome and performance measurements
    • Harris K.M, Griffin B.A., McCaffrey D.F., Morral A.R. Inconsistencies in self-reported drug use by adolescents in substance abuse treatment: implications for outcome and performance measurements. J. Subst. Abuse Treat. 2008, 34:347-355.
    • (2008) J. Subst. Abuse Treat. , vol.34 , pp. 347-355
    • Harris, K.M.1    Griffin, B.A.2    McCaffrey, D.F.3    Morral, A.R.4
  • 25
    • 82555168716 scopus 로고    scopus 로고
    • Comparing Drug Testing and Self-Report of Drug Use among Youths and Young Adults in the General Population. Substance Abuse and Mental Health Services Administration. DHHS Publication No. SMA 07-4249, Rockville, MD.
    • Harrison, L.D., Martin, S.S., Enev, T., Harrington, D., 2007. Comparing Drug Testing and Self-Report of Drug Use among Youths and Young Adults in the General Population. Substance Abuse and Mental Health Services Administration. DHHS Publication No. SMA 07-4249, Rockville, MD.
    • (2007)
    • Harrison, L.D.1    Martin, S.S.2    Enev, T.3    Harrington, D.4
  • 26
    • 43049099967 scopus 로고    scopus 로고
    • Occurrence of psychoactive stimulatory drugs in wastewaters in north-eastern Spain
    • Huerta-Fontela M., Galceran M.T., Martin-Alonso J., Ventura F. Occurrence of psychoactive stimulatory drugs in wastewaters in north-eastern Spain. Sci. Total Environ. 2008, 397:31-40. 10.1016/j.scitotenv.2008.02.057.
    • (2008) Sci. Total Environ. , vol.397 , pp. 31-40
    • Huerta-Fontela, M.1    Galceran, M.T.2    Martin-Alonso, J.3    Ventura, F.4
  • 27
    • 51949109060 scopus 로고    scopus 로고
    • Stimulatory drugs of abuse in surface waters and their removal in a conventional drinking water treatment plant
    • Huerta-Fontela M., Galceran M.T., Ventura F. Stimulatory drugs of abuse in surface waters and their removal in a conventional drinking water treatment plant. Environ. Sci. Technol. 2008, 42:6809-6816. 10.1021/es800768h.
    • (2008) Environ. Sci. Technol. , vol.42 , pp. 6809-6816
    • Huerta-Fontela, M.1    Galceran, M.T.2    Ventura, F.3
  • 28
    • 0023919322 scopus 로고
    • Cocaine: analysis, pharmacokinetics, and metabolic disposition
    • Jatlow P. Cocaine: analysis, pharmacokinetics, and metabolic disposition. Yale J. Biol. Med. 1988, 61:105.
    • (1988) Yale J. Biol. Med. , vol.61 , pp. 105
    • Jatlow, P.1
  • 29
    • 2942687251 scopus 로고    scopus 로고
    • Protocols for stability and homogeneity studies of drugs for its application to doping control
    • Jiménez C., Ventura R., Segura J., de la Torre R. Protocols for stability and homogeneity studies of drugs for its application to doping control. Anal. Chim. Acta 2004, 515:323-331.
    • (2004) Anal. Chim. Acta , vol.515 , pp. 323-331
    • Jiménez, C.1    Ventura, R.2    Segura, J.3    de la Torre, R.4
  • 30
    • 77955697397 scopus 로고    scopus 로고
    • Estimation of illicit drugs consumption by wastewater analysis in Paris area (France)
    • Karolak S., Nefau T., Bailly E., Solgadi A., Levi Y. Estimation of illicit drugs consumption by wastewater analysis in Paris area (France). Forensic Sci. Int. 2010, 200:153-160. 10.1016/j.forsciint.2010.04.007.
    • (2010) Forensic Sci. Int. , vol.200 , pp. 153-160
    • Karolak, S.1    Nefau, T.2    Bailly, E.3    Solgadi, A.4    Levi, Y.5
  • 31
    • 64149101143 scopus 로고    scopus 로고
    • Illicit drugs and pharmaceuticals in the environment-forensic applications of environmental data. Part 1. Estimation of the usage of drugs in local communities
    • Kasprzyk-Hordern B., Dinsdale R.M., Guwy A.J. Illicit drugs and pharmaceuticals in the environment-forensic applications of environmental data. Part 1. Estimation of the usage of drugs in local communities. Environ. Pollut. 2009, 157:1773-1777.
    • (2009) Environ. Pollut. , vol.157 , pp. 1773-1777
    • Kasprzyk-Hordern, B.1    Dinsdale, R.M.2    Guwy, A.J.3
  • 32
    • 77952704879 scopus 로고    scopus 로고
    • Estimated drug use based on direct questioning and open-ended questions: responses in the 2006 National Survey on Drug Use and Health
    • Kroutil L.A., Vorburger M., Aldworth J., Colliver J.D. Estimated drug use based on direct questioning and open-ended questions: responses in the 2006 National Survey on Drug Use and Health. Int. J. Methods Psychiatr. Res. 2010, 19:74-87.
    • (2010) Int. J. Methods Psychiatr. Res. , vol.19 , pp. 74-87
    • Kroutil, L.A.1    Vorburger, M.2    Aldworth, J.3    Colliver, J.D.4
  • 34
    • 0038347311 scopus 로고    scopus 로고
    • Cocaethylene metabolism and interaction with cocaine and ethanol: role of carboxylesterases
    • Laizure C.S., Mandrell T., Gades N.M., Parker R.B. Cocaethylene metabolism and interaction with cocaine and ethanol: role of carboxylesterases. Drug Metab. Dispos. 2003, 31:16-20.
    • (2003) Drug Metab. Dispos. , vol.31 , pp. 16-20
    • Laizure, C.S.1    Mandrell, T.2    Gades, N.M.3    Parker, R.B.4
  • 39
    • 77956546379 scopus 로고    scopus 로고
    • Sampling for pharmaceuticals and personal care products (PPCPs) and illicit drugs in wastewater systems: are your conclusions valid? A critical review
    • Ort C., Lawrence M.G., Rieckermann J., Joss A. Sampling for pharmaceuticals and personal care products (PPCPs) and illicit drugs in wastewater systems: are your conclusions valid? A critical review. Environ. Sci. Technol. 2010, 44:6024-6035. 10.1021/es100779n.
    • (2010) Environ. Sci. Technol. , vol.44 , pp. 6024-6035
    • Ort, C.1    Lawrence, M.G.2    Rieckermann, J.3    Joss, A.4
  • 40
    • 0036792349 scopus 로고    scopus 로고
    • Duration of detectable methamphetamine and amphetamine excretion in urine after controlled oral administration of methamphetamine to humans
    • Oyler J.M., Cone E.J., Joseph R.E., Moolchan E.T., Huestis M.A. Duration of detectable methamphetamine and amphetamine excretion in urine after controlled oral administration of methamphetamine to humans. Clin. Chem. 2002, 48:1703-1714.
    • (2002) Clin. Chem. , vol.48 , pp. 1703-1714
    • Oyler, J.M.1    Cone, E.J.2    Joseph, R.E.3    Moolchan, E.T.4    Huestis, M.A.5
  • 41
    • 56449098373 scopus 로고    scopus 로고
    • Analysis of drugs of abuse and their human metabolites in water by LC-MS2: a non-intrusive tool for drug abuse estimation at the community level
    • Postigo C., Lopezdealda M., Barcelo D. Analysis of drugs of abuse and their human metabolites in water by LC-MS2: a non-intrusive tool for drug abuse estimation at the community level. Trends Anal. Chem. 2008, 27:1053-1069.
    • (2008) Trends Anal. Chem. , vol.27 , pp. 1053-1069
    • Postigo, C.1    Lopezdealda, M.2    Barcelo, D.3
  • 42
    • 78349308631 scopus 로고    scopus 로고
    • Evaluation of drugs of abuse use and trends in a prison through wastewater analysis
    • Postigo C., López de Alda M., Barceló D. Evaluation of drugs of abuse use and trends in a prison through wastewater analysis. Environ. Int. 2011, 37:49-55. 10.1016/j.envint.2010.06.012.
    • (2011) Environ. Int. , vol.37 , pp. 49-55
    • Postigo, C.1    López de Alda, M.2    Barceló, D.3
  • 43
    • 0019431991 scopus 로고
    • The effect of age on the pharmacokinetics of metoprolol and its metabolites
    • Quarterman C.P., Kendall M.J., Jack D.B. The effect of age on the pharmacokinetics of metoprolol and its metabolites. Br. J. Clin. Pharmacol. 1981, 11:287-294.
    • (1981) Br. J. Clin. Pharmacol. , vol.11 , pp. 287-294
    • Quarterman, C.P.1    Kendall, M.J.2    Jack, D.B.3
  • 44
    • 54349095319 scopus 로고    scopus 로고
    • Identification and structural characterization of biodegradation products of atenolol and glibenclamide by liquid chromatography coupled to hybrid quadrupole time-of-flight and quadrupole ion trap mass spectrometry
    • Radjenovic J., Perez S., Petrovic M., Barcelo D. Identification and structural characterization of biodegradation products of atenolol and glibenclamide by liquid chromatography coupled to hybrid quadrupole time-of-flight and quadrupole ion trap mass spectrometry. J. Chromatogr. A. 2008, 1210:142-153.
    • (2008) J. Chromatogr. A. , vol.1210 , pp. 142-153
    • Radjenovic, J.1    Perez, S.2    Petrovic, M.3    Barcelo, D.4
  • 46
    • 80052022245 scopus 로고    scopus 로고
    • Analysis and interpretation of specific ethanol metabolites, ethyl sulfate and ethyl glucuronide, in sewage effluent for the quantitative measurement of regional alcohol consumption
    • Reid M.J., Langford K.H., Mørland J., Thomas K.V. Analysis and interpretation of specific ethanol metabolites, ethyl sulfate and ethyl glucuronide, in sewage effluent for the quantitative measurement of regional alcohol consumption. Alcohol. Clin. Exp. Res. 2011, 35(9):1-7. 10.1111/j.1530-0277.2011.01505.x.
    • (2011) Alcohol. Clin. Exp. Res. , vol.35 , Issue.9 , pp. 1-7
    • Reid, M.J.1    Langford, K.H.2    Mørland, J.3    Thomas, K.V.4
  • 47
    • 73449147015 scopus 로고    scopus 로고
    • Cytotoxic drugs in drinking water: a prediction and risk assessment exercise for the Thames catchment in the United Kingdom
    • Rowney N.C., Johnson A.C., Williams R.J. Cytotoxic drugs in drinking water: a prediction and risk assessment exercise for the Thames catchment in the United Kingdom. Environ. Toxicol. Chem. 2009, 28:2733-2743.
    • (2009) Environ. Toxicol. Chem. , vol.28 , pp. 2733-2743
    • Rowney, N.C.1    Johnson, A.C.2    Williams, R.J.3
  • 49
    • 33646593148 scopus 로고    scopus 로고
    • Urinary excretion of the main metabolites of methamphetamine, including p-hydroxymethamphetamine-sulfate and p-hydroxymethamphetamine-glucuronide, in humans and rats
    • Shima N., Kamata H.T., Katagi M., Tsuchihashi H. Urinary excretion of the main metabolites of methamphetamine, including p-hydroxymethamphetamine-sulfate and p-hydroxymethamphetamine-glucuronide, in humans and rats. Xenobiotica 2006, 36:259-267.
    • (2006) Xenobiotica , vol.36 , pp. 259-267
    • Shima, N.1    Kamata, H.T.2    Katagi, M.3    Tsuchihashi, H.4
  • 50
    • 0024160710 scopus 로고
    • Urinary excretion of p-hydroxylated methamphetamine metabolites in man. II. Effect of alcohol intake on methamphetamine metabolism
    • Shimosato K. Urinary excretion of p-hydroxylated methamphetamine metabolites in man. II. Effect of alcohol intake on methamphetamine metabolism. Pharmacol. Biochem. Behav. 1988, 29:733-740.
    • (1988) Pharmacol. Biochem. Behav. , vol.29 , pp. 733-740
    • Shimosato, K.1
  • 51
    • 0023763373 scopus 로고
    • Biphasic effects of alcohol drinking on methamphetamine metabolism in man
    • Shimosato K., Oda H., Ohmae M., Tomita M., Doi Y. Biphasic effects of alcohol drinking on methamphetamine metabolism in man. Alcohol Alcohol. 1988, 23:351-357.
    • (1988) Alcohol Alcohol. , vol.23 , pp. 351-357
    • Shimosato, K.1    Oda, H.2    Ohmae, M.3    Tomita, M.4    Doi, Y.5
  • 54
    • 82555193167 scopus 로고    scopus 로고
    • Substance Abuse and Mental Health Services Administration. Results from the 2008 National Survey on Drug Use and Health: National Findings. Office of Applied Studies NSDUH Series H-36. Office of Applied Studies, NSDUH Series H-36, Rockville, MD.
    • Substance Abuse and Mental Health Services Administration, 2009. Results from the 2008 National Survey on Drug Use and Health: National Findings. Office of Applied Studies NSDUH Series H-36. Office of Applied Studies, NSDUH Series H-36, Rockville, MD.
    • (2009)
  • 55
    • 77953356047 scopus 로고    scopus 로고
    • Relating environmental concentrations of pharmaceuticals to consumption: a mass balance approach for the river Rhine
    • ter Laak T.L., van der Aa M., Houtman C.J., Stoks P.G., van Wezel A.P. Relating environmental concentrations of pharmaceuticals to consumption: a mass balance approach for the river Rhine. Environ. Int. 2010, 36:403-409.
    • (2010) Environ. Int. , vol.36 , pp. 403-409
    • ter Laak, T.L.1    van der Aa, M.2    Houtman, C.J.3    Stoks, P.G.4    van Wezel, A.P.5
  • 56
    • 55349146810 scopus 로고    scopus 로고
    • Nova Publishers, New York, G.H. Toolaney (Ed.)
    • New Research on Methamphetamine Abuse 2007, Nova Publishers, New York. G.H. Toolaney (Ed.).
    • (2007) New Research on Methamphetamine Abuse
  • 58
    • 61849154198 scopus 로고    scopus 로고
    • Spatial and temporal variations in the occurrence of cocaine and benzoylecgonine in waste-and surface water from Belgium and removal during wastewater treatment
    • van Nuijs A., Pecceu B., Theunis L., Dubois N., Charlier C., Jorens P.G., Bercoets L., Blust R., Neels H., Covaci A. Spatial and temporal variations in the occurrence of cocaine and benzoylecgonine in waste-and surface water from Belgium and removal during wastewater treatment. Water Res. 2009, 43:1341-1349.
    • (2009) Water Res. , vol.43 , pp. 1341-1349
    • van Nuijs, A.1    Pecceu, B.2    Theunis, L.3    Dubois, N.4    Charlier, C.5    Jorens, P.G.6    Bercoets, L.7    Blust, R.8    Neels, H.9    Covaci, A.10
  • 60
    • 0024431327 scopus 로고
    • Cetirizine: a pharmacokinetic and pharmacodynamic evaluation in children with seasonal allergic rhinitis
    • Watson W.T.A., Simons K.J., Chen X.Y., Simons F.E.R. Cetirizine: a pharmacokinetic and pharmacodynamic evaluation in children with seasonal allergic rhinitis. J. Allergy Clin. Immunol. 1989, 84:457-464.
    • (1989) J. Allergy Clin. Immunol. , vol.84 , pp. 457-464
    • Watson, W.T.A.1    Simons, K.J.2    Chen, X.Y.3    Simons, F.E.R.4
  • 61
    • 0023465461 scopus 로고
    • The metabolism and pharmacokinetics of 14C-cetirizine in humans
    • Wood S.G., Chasseaud L.F., Yeh J., Chung M. The metabolism and pharmacokinetics of 14C-cetirizine in humans. Ann. Allergy 1987, 59:31-34.
    • (1987) Ann. Allergy , vol.59 , pp. 31-34
    • Wood, S.G.1    Chasseaud, L.F.2    Yeh, J.3    Chung, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.