PKA-dependent regulation of Cdc25 RasGEF localization in budding yeast

FEBS Letters

Volumn 585, Issue 24, 2011, Pages 3914-3920

  Belotti, Fiorella ^a   Tisi, Renata ^a   Paiardi, Chiara ^a,b   Groppi, Silvia ^a   Martegani, Enzo ^a  

^a UNIVERSITY OF MILANO BICOCCA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

Endoplasmic reticulum; Phosphorylation; Saccharomyces cerevisiae

Indexed keywords

ADENYLATE CYCLASE; ALANINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; GUANINE NUCLEOTIDE EXCHANGE FACTOR; GUANOSINE TRIPHOSPHATASE ACTIVATING PROTEIN; PROTEIN TYROSINE PHOSPHATASE; RAS PROTEIN; SERINE;

ARTICLE; CARBOXY TERMINAL SEQUENCE; CATALYSIS; CELL MEMBRANE; CELL VOLUME; CYTOSOL; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME REGULATION; EPIFLUORESCENCE MICROSCOPY; FUNGUS GROWTH; GLYCOGEN ANALYSIS; NONHUMAN; NUCLEAR EXPORT SIGNAL; NUCLEAR LOCALIZATION SIGNAL; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SACCHAROMYCES CEREVISIAE; SEQUENCE ANALYSIS;

ACTIVE TRANSPORT, CELL NUCLEUS; CATALYTIC DOMAIN; CELL MEMBRANE; CELL NUCLEUS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; GENE EXPRESSION REGULATION, FUNGAL; PHOSPHORYLATION; RAS-GRF1; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE; SACCHAROMYCETALES;

EID: 82555187069     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.10.032     Document Type: Article

References (28)

1. J. Thevelein, and J. de Winde Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae Mol. Microbiol. 33 1999 904 918 (Pubitemid 29425244)
2. S. Jones, M. Vignais, and J. Broach The CDC25 protein of Saccharomyces cerevisiae promotes exchange of guanine nucleotides bound to ras Mol. Cell. Biol. 11 1991 2641 2646 (Pubitemid 21895643)
3. K. Tanaka, M. Nakafuku, F. Tamanoi, Y. Kaziro, K. Matsumoto, and A. Toh-e IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein Mol. Cell. Biol. 10 1990 4303 4313
4. M. Vanoni, M. Vavassori, G. Frascotti, E. Martegani, and L. Alberghina Overexpression of the CDC25 gene, an upstream element of the RAS/adenylyl cyclase pathway in Saccharomyces cerevisiae, allows immunological identification and characterization of its gene product Biochem. Biophys. Res. Commun. 172 1990 61 69 (Pubitemid 20352500)
5. H. Garreau, M. Geymonat, G. Renault, and M. Jacquet Membrane-anchoring domains of Cdc25p, a Saccharomyces cerevisiae ras exchange factor Biol. Cell 86 1996 93 102 (Pubitemid 26345716)
6. E. Gross, D. Goldberg, and A. Levitzki Phosphorylation of the S. cerevisiae Cdc25 in response to glucose results in its dissociation from Ras Nature 360 1992 762 765 (Pubitemid 23012278)
7. J. Dong, and X. Bai The membrane localization of Ras2p and the association between Cdc25p and Ras2-GTP are regulated by protein kinase A (PKA) in the yeast Saccharomyces cerevisiae FEBS Lett. 585 2011 1127 1134
8. D. Jian, Z. Aili, B. Xiaojia, Z. Huansheng, and H. Yun Feedback regulation of Ras2 guanine nucleotide exchange factor (Ras2-GEF) activity of Cdc25p by Cdc25p phosphorylation in the yeast Saccharomyces cerevisiae FEBS Lett. 584 2010 4745 4750
9. S.J. Deminoff, V. Ramachandran, and P.K. Herman Distal recognition sites in substrates are required for efficient phosphorylation by the cAMP-dependent protein kinase Genetics 182 2009 529 539
10. R. Tisi, F. Belotti, C. Paiardi, F. Brunetti, and E. Martegani The budding yeast RasGEF Cdc25 reveals an unexpected nuclear localization Biochim. Biophys. Acta 1783 2008 2363 2374
11. A. Wach, A. Brachat, R. Pöhlmann, and P. Philippsen New heterologous modules for classical or PCR-based gene disruptions in Saccharomyces cerevisiae Yeast 10 1994 1793 1808
12. F. Tripodi, V. Zinzalla, M. Vanoni, L. Alberghina, and P. Coccetti In CK2 inactivated cells the cyclin dependent kinase inhibitor Sic1 is involved in cell-cycle arrest before the onset of S phase Biochem. Biophys. Res. Commun. 359 2007 921 927 (Pubitemid 46946905)
13. A. Gross, S. Winograd, I. Marbach, and A. Levitzki The N-terminal half of Cdc25 is essential for processing glucose signaling in Saccharomyces cerevisiae Biochemistry 38 1999 13252 13262
14. D. Broek, T. Toda, T. Michaeli, L. Levin, C. Birchmeier, M. Zoller, S. Powers, and M. Wigler The S. cerevisiae CDC25 gene product regulates the RAS/adenylate cyclase pathway Cell 48 1987 789 799
15. F. Belotti, R. Tisi, and E. Martegani The N-terminal region of the Saccharomyces cerevisiae RasGEF Cdc25 is required for nutrient-dependent cell-size regulation Microbiology 152 2006 1231 1242
16. S. Colombo, P. Ma, L. Cauwenberg, J. Winderickx, M. Crauwels, A. Teunissen, D. Nauwelaers, J.H. de Winde, M.F. Gorwa, D. Colavizza, and J.M. Thevelein Involvement of distinct G-proteins, Gpa2 and Ras, in glucose- and intracellular acidification-induced cAMP signalling in the yeast Saccharomyces cerevisiae EMBO J. 17 1998 3326 3341 (Pubitemid 28279507)
17. F. Sidoux-Walter, N. Pettersson, and S. Hohmann The Saccharomyces cerevisiae aquaporin Aqy1 is involved in sporulation Proc. Natl. Acad. Sci. USA 101 2004 17422 17427 (Pubitemid 39657420)
18. L. Popolo, and M. Vai The Gas1 glycoprotein, a putative wall polymer cross-linker Biochim. Biophys. Acta 1426 1999 385 400 (Pubitemid 29027953)
19. J. Jungmann, and S. Munro Multi-protein complexes in the cis Golgi of Saccharomyces cerevisiae with alpha-1,6-mannosyltransferase activity EMBO J. 17 1998 423 434 (Pubitemid 28045483)
20. C. Meisinger, T. Sommer, and N. Pfanner Purification of Saccharomcyes cerevisiae mitochondria devoid of microsomal and cytosolic contaminations Anal. Biochem. 287 2000 339 342 (Pubitemid 32006247)
21. D. Klionsky, and S. Emr Membrane protein sorting: biosynthesis, transport and processing of yeast vacuolar alkaline phosphatase EMBO J. 8 1989 2241 2250 (Pubitemid 19273302)
22. J. Fuchs, and J. Loidl Behaviour of nucleolus organizing regions (NORs) and nucleoli during mitotic and meiotic divisions in budding yeast Chromosome Res. 12 2004 427 438
23. R. Serrano Structure, function and regulation of plasma membrane H(+)-ATPase FEBS Lett. 325 1993 108 111 (Pubitemid 23201870)
24. T. Kaplon, and M. Jacquet The cellular content of Cdc25p, the Ras exchange factor in Saccharomyces cerevisiae, is regulated by destabilization through a cyclin destruction box J. Biol. Chem. 270 1995 20742 20747
25. H. Chautard, M. Jacquet, F. Schoentgen, N. Bureaud, and H. Bénédetti Tfs1p, a member of the PEBP family, inhibits the Ira2p but not the Ira1p Ras GTPase-activating protein in Saccharomyces cerevisiae Eukaryot. Cell 3 2004 459 470 (Pubitemid 38497984)
26. J. Leadsham, K. Miller, K. Ayscough, S. Colombo, E. Martegani, P. Sudbery, and C. Gourlay Whi2p links nutritional sensing to actin-dependent Ras-cAMP-PKA regulation and apoptosis in yeast J. Cell Sci. 122 2009 706 715
27. K. Mintzer, and J. Field The SH3 domain of the S. cerevisiae Cdc25p binds adenylyl cyclase and facilitates Ras regulation of cAMP signalling Cell. Signal. 11 1999 127 135 (Pubitemid 29056170)
28. S. Bhattacharya, L. Chen, J. Broach, and S. Powers Ras membrane targeting is essential for glucose signaling but not for viability in yeast Proc. Natl. Acad. Sci. USA 92 1995 2984 2988