The membrane localization of Ras2p and the association between Cdc25p and Ras2-GTP are regulated by protein kinase A (PKA) in the yeast Saccharomyces cerevisiae

FEBS Letters

Volumn 585, Issue 8, 2011, Pages 1127-1134

  Dong, Jian ^a   Bai, Xiaojia ^a  

^a TIANJIN UNIVERSITY   (China)

Author keywords

Cdc25p; Localization; Ras2 GTP; Ras2p; Saccharomyces cerevisiae

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; PROTEIN TYROSINE PHOSPHATASE; RAS PROTEIN; RAS PROTEIN 2; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME REGULATION; FEEDBACK SYSTEM; MEMBRANE TRANSPORT; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; PROTEIN LOCALIZATION; SACCHAROMYCES CEREVISIAE;

CELL MEMBRANE; CYCLIC AMP; CYCLIC AMP-DEPENDENT PROTEIN KINASE CATALYTIC SUBUNITS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; CYTOPLASM; GREEN FLUORESCENT PROTEINS; GUANOSINE TRIPHOSPHATE; IMMUNOBLOTTING; MICROSCOPY, FLUORESCENCE; MUTATION; PHOSPHORYLATION; PROTEIN BINDING; RAS GUANINE NUCLEOTIDE EXCHANGE FACTORS; RAS PROTEINS; RAS-GRF1; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

SACCHAROMYCES CEREVISIAE;

EID: 79954438971     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.03.057     Document Type: Article

References (29)

1. J.R. Broach, and R.J. Deschenes The function of Ras genes in Saccharomyces Cerevisiae Adv. Cancer Res. 54 1990 79 139 (Pubitemid 20088336)
2. A. Hall, C.J. Marshall, N.K. Spurr, and R.A. Weiss Identification of transforming gene in two human sarcoma cell lines as a new member of the ras gene family located on chromosome 1 Nature 303 1983 396 400 (Pubitemid 13094876)
3. J.M. Thevelein, and J.H. De Winde Novel sensing mechanisms and targets for the cAMP-protein kinase A pathway in the yeast Saccharomyces cerevisiae Mol. Microbiol. 33 1999 904 918 (Pubitemid 29425244)
4. K. Tanaka, M. Nakafuku, T. Satoh, M.S. Marshall, J.B. Gibbs, K. Matsumoto, Y. Kaziro, and A. Toh-e S. cerevisiae genes IRA1 and IRA2 encode proteins that may be functionally equivalent to mammalian ras GTPase activating protein Cell 60 1990 803 807
5. L.C. Robinson, J.B. Gibbs, M.S. Marshall, I.S. Sigal, and K. Tatchell CDC25: a component of the RAS-adenylate cyclase pathway in Saccharomyces cerevisiae Science 235 1987 1218 1221 (Pubitemid 17034010)
6. H. Garreau, J.H. Camonis, C. Guitton, and M. Jacquet The Saccharomyces cerevisiae CDC25 gene product is a 180 kDa polypeptide and is associated with a membrane fraction FEBS Lett. 269 1990 53 59 (Pubitemid 20245315)
7. J.L. Folch-Mallol, L.M. Martinez, S.J. Casas, R. Yang, C. Martínez-Anaya, L. López, A. Hernández, and J. Nieto-Sotelo New roles for CDC25 in growth control, galactose regulation and cellular differentiation in Saccharomyces cerevisiae Microbiology 150 2004 2865 2879 (Pubitemid 39317789)
8. E. Boy-Marcotte, P. Ikonomi, and M. Jacquet SDC25, a dispensable Ras guanine nucleotide exchange factor of Saccharomyces cerevisiae differs from CDC25 by its regulation Mol. Biol. Cell 7 1996 529 539 (Pubitemid 26112561)
9. D. Broek, N. Samiy, O. Fasano, A. Fujiyama, F. Tamanoi, J. Northup, and M. Wigler Differential activation of yeast adenylate cyclase by wild type and mutant RAS proteins Cell 41 1985 763 769 (Pubitemid 15243383)
10. J. Nikawa, P. Sass, and M. Wigler Cloning and characterization of the low-affinity cyclic AMP phosphodiesterase gene of Saccharomyces cerevisiae Mol. Cell. Biol. 7 1987 3629 3636
11. J.-I. Park, C.M. Grant, and I.W. Dawes The high-affinity cAMP phosphodiesterase of Saccharomyces cerevisiae is the major determinant of cAMP levels in stationary phase: involvement of different branches of the Ras-cyclic AMP pathway in stress responses Biochem. Biophys. Res. Commun. 327 2005 311 319 (Pubitemid 40051386)
12. T. Toda, S. Cameron, P. Sass, M. Zoller, and M. Wigler Three different genes in S. cerevisiae encode the catalytic subunits of the cAMP-dependent protein kinase Cell 50 1987 277 287
13. T. Toda, S. Cameron, P. Sass, M. Zoller, J.D. Scott, B. McMullen, M. Hurwitz, E.G. Krebs, and M. Wigler Cloning and characterization of BCY1, a locus encoding a regulatory subunit of the cyclic AMP-dependent protein kinase in Saccharomyces cerevisiae Mol. Cell. Biol. 7 1987 1371 1377 (Pubitemid 17045225)
14. J. Nikawa, S. Cameron, T. Toda, K.M. Ferguson, and M. Wigler Rigorous feedback control of cAMP levels in Saccharomyces cerevisiae Genes Dev. 1 1987 931 937
15. P. Ma, S. Wera, P. Van Dijck, and J.M. Thevelein The PDE1-encoded low-affinity phosphodiesterase in the yeast Saccharomyces cerevisiae Has a specific function in controlling agonist-induced cAMP signaling Mol. Biol. Cell 10 1999 91 104 (Pubitemid 29156929)
16. Y. Hu, E. Liu, X. Bai, and A. Zhang The localization and concentration of the PDE2-encoded high-affinity cAMP phosphodiesterase is regulated by cAMP-dependent protein kinase A in the yeast Saccharomyces cerevisiae FEMS Yeast Res. 10 2009 177 187
17. J.L. Whistler, and J. Rine Ras2 and Ras1 protein phosphorylation in Saccharomyces cerevisiae J. Biol. Chem. 272 1997 18790 18800 (Pubitemid 27318226)
18. S. Colombo, D. Ronchetti, J.M. Thevelein, J. Winderickx, and E. Martegani Activation state of the Ras2 protein and glucose-induced signaling in Saccharomyces cerevisiae J. Biol. Chem. 279 2004 46715 46722 (Pubitemid 39518319)
19. K. Tanaka, K. Matsumoto, and A. Toh-E IRA1, an inhibitory regulator of the RAS-cyclic AMP pathway in Saccharomyces cerevisiae Mol. Cell. Biol. 9 1989 757 768 (Pubitemid 19038876)
20. K. Tanaka, M. Nakafuku, F. Tamanoi, Y. Kaziro, K. Matsumoto, and A. Toh-e IRA2, a second gene of Saccharomyces cerevisiae that encodes a protein with a domain homologous to mammalian ras GTPase-activating protein Mol. Cell. Biol. 10 1990 4303 4313
21. E. Gross, D. Goldberg, and A. Levitzki Phosphorylation of the S. cerevisiae Cdc25 in response to glucose results in its dissociation from Ras Nature 360 1992 762 765 (Pubitemid 23012278)
22. D. Jian, Z. Aili, B. Xiaojia, Z. Huansheng, and H. Yun Feedback regulation of Ras2 guanine nucleotide exchange factor (Ras2-GEF) activity of Cdc25p by Cdc25p phosphorylation in the yeast Saccharomyces cerevisiae FEBS Lett. 584 2010 4745 4750
23. R.D. Gietz, and S. Akio New yeast-Escherichia coli shuttle vectors constructed with in vitro mutagenized yeast genes lacking six-base pair restriction sites Gene 74 1988 527 534 (Pubitemid 19060666)
24. S. Garrett, and J. Broach Loss of Ras activity in Saccharomyces cerevisiae is suppressed by disruptions of a new kinase gene, YAKI, whose product may act downstream of the cAMP-dependent protein kinase Genes Dev. 3 1989 1336 1348
25. J.B. Créchet, P. Poullet, J. Camonis, M. Jacquet, and A. Parmeggiani Different kinetic properties of the two mutants, RAS2Ile152 and RAS2Val19, that suppress the CDC25 requirement in RAS/adenylate cyclase pathway in Saccharomyces cerevisiae J. Biol. Chem. 265 1990 1563 1568
26. A. Smith, M.P. Ward, and S. Garrett Yeast PKA represses Msn2p/Msn4p-dependent gene expression to regulate growth, stress response and glycogen accumulation EMBO J. 17 1998 3556 3564 (Pubitemid 28327374)
27. B. Xiaojia, and D. Jian Serine214 of Ras2p plays a role in the feedback regulation of the Ras-cAMP pathway in the yeast Saccharomyces cerevisiae FEBS Lett. 584 2010 2333 2338
28. T. Munder, and P. Fürst The Saccharomyces cerevisiae CDC25 gene product binds specifically to catalytically inactive ras proteins in vivo Mol. Cell. Biol. 12 1992 2091 2099
29. S. Powers, K. O'Neill, and M. Wigler Dominant yeast and mammalian RAS mutants that interfere with the CDC25-dependent activation of wild-type RAS in Saccharomyces cerevisiae Mol. Cell. Biol. 9 1989 390 395 (Pubitemid 19038848)