Human anti-V3 HIV-1 monoclonal antibodies encoded by the VH5-51/VL lambda genes define a conserved antigenic structure

PLoS ONE

Volumn 6, Issue 12, 2011, Pages

  Gorny, Miroslaw K ^a   Sampson, Jared ^a   Li, Huiguang ^a   Jiang, Xunqing ^a   Totrov, Maxim ^b   Wang, Xiao Hong ^c   Williams, Constance ^a   O'Neal, Timothy ^a   Volsky, Barbara ^a   Li, Liuzhe ^a   Cardozo, Timothy ^a   Nyambi, Phillipe ^a,c   Zolla Pazner, Susan ^a,c   Kong, Xiang Peng ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b MOLSOFT LLC   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN F(AB) FRAGMENT; IMMUNOGLOBULIN HEAVY CHAIN; IMMUNOGLOBULIN LAMBDA CHAIN; MONOCLONAL ANTIBODY; MONOCLONAL ANTIBODY V3; UNCLASSIFIED DRUG; EPITOPE; HUMAN IMMUNODEFICIENCY VIRUS ANTIBODY; IMMUNOGLOBULIN; IMMUNOGLOBULIN FRAGMENT; NEUTRALIZING ANTIBODY; PEPTIDE;

AMINO ACID SEQUENCE; ANTIBODY COMBINING SITE; ANTIBODY SPECIFICITY; ANTIGEN STRUCTURE; ARTICLE; COMPLEMENTARITY DETERMINING REGION; CONTROLLED STUDY; CRYSTALLOGRAPHY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; IMMUNOGLOBULIN GENE; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; PROTEIN DOMAIN; B LYMPHOCYTE; BINDING SITE; CHEMICAL STRUCTURE; CHEMISTRY; CONFORMATION; METHODOLOGY; MOLECULAR GENETICS; PROTEIN TERTIARY STRUCTURE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VIROLOGY; X RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANTIBODIES, MONOCLONAL; ANTIBODIES, NEUTRALIZING; ANTIBODY SPECIFICITY; B-LYMPHOCYTES; BINDING SITES; COMPLEMENTARITY DETERMINING REGIONS; CRYSTALLOGRAPHY, X-RAY; EPITOPES; HIV ANTIBODIES; HUMANS; IMMUNOGLOBULIN FRAGMENTS; IMMUNOGLOBULINS; MODELS, MOLECULAR; MOLECULAR CONFORMATION; MOLECULAR SEQUENCE DATA; PEPTIDES; PROTEIN STRUCTURE, TERTIARY; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION;

EID: 82555170601     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0027780     Document Type: Article

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