MR Imaging of the Newborn: A Technical Perspective

Magnetic Resonance Imaging Clinics of North America

Volumn 20, Issue 1, 2012, Pages 63-79

  Hillenbrand, Claudia M ^a   Reykowski, Arne ^b  

^a ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

^b Invivo Corporation   (United States)

Author keywords

Magnetic resonance imaging; MR safety; MR compatible Incubator; Neonate; Newborn RF coil; NICU MR imaging

Indexed keywords

ARTIFICIAL VENTILATION; BODY TEMPERATURE MONITORING; EAR PROTECTION; FLUID THERAPY; HEART RATE; HUMAN; IMAGING SYSTEM; INCUBATOR; INFUSION PUMP; INTENSIVE CARE UNIT; MEDICAL INSTRUMENTATION; NEWBORN; NEWBORN MONITORING; NEWBORN SCREENING; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OXIMETER; OXYGEN SATURATION; PATIENT CARE; PATIENT TRANSPORT; PEDIATRICS; RADIATION EQUIPMENT; RADIATION EXPOSURE; RADIOFREQUENCY; RESUSCITATION; REVIEW; RISK FACTOR; SAFETY; SEDATION; VENTILATOR;

EQUIPMENT DESIGN; FEMALE; HUMANS; INFANT, NEWBORN; INFANT, NEWBORN, DISEASES; MAGNETIC RESONANCE IMAGING; MALE; NEONATAL SCREENING;

EID: 82455220953     PISSN: 10649689     EISSN: 15579786     Source Type: Journal    
DOI: 10.1016/j.mric.2011.10.002     Document Type: Review

References (72)

1. Mathur A.M., Neil J.J., McKinstry R.C., et al. Transport, monitoring, and successful brain MR imaging in unsedated neonates. Pediatr Radiol 2008, 38(3):260-264.
2. van Wezel-Meijler G., Leijser L.M., de Bruine F.T., et al. Magnetic resonance imaging of the brain in newborn infants: practical aspects. Early Hum Dev 2009, 85(2):85-92.
3. Counsell S.J., Rutherford M.A., Cowan F.M., et al. Magnetic resonance imaging of preterm brain injury. Arch Dis Child Fetal Neonatal Ed 2003, 88(4):F269-F274.
4. Rona Z., Klebermass K., Cardona F., et al. Comparison of neonatal MRI examinations with and without an MR-compatible incubator: advantages in examination feasibility and clinical decision-making. Eur J Paediatr Neurol 2010, 14(5):410-417.
5. Woodward L.J., Anderson P.J., Austin N.C., et al. Neonatal MRI to predict neurodevelopmental outcomes in preterm infants. N Engl J Med 2006, 355(7):685-694.
6. Ment L.R., Bada H.S., Barnes P., et al. Practice parameter: neuroimaging of the neonate: report of the Quality Standards Subcommittee of the American Academy of Neurology and the Practice Committee of the Child Neurology Society. Neurology 2002, 58(12):1726-1738.
7. O'Shea T.M., Counsell S.J., Bartels D.B., et al. Magnetic resonance and ultrasound brain imaging in preterm infants. Early Hum Dev 2005, 81(3):263-271.
8. Leijser L.M., Liauw L., Veen S., et al. Comparing brain white matter on sequential cranial ultrasound and MRI in very preterm infants. Neuroradiology 2008, 50(9):799-811.
9. Panigrahy A., Bluml S. Advances in magnetic resonance neuroimaging techniques in the evaluation of neonatal encephalopathy. Top Magn Reson Imaging 2007, 18(1):3-29.
10. Panigrahy A., Borzage M., Bluml S. Basic principles and concepts underlying recent advances in magnetic resonance imaging of the developing brain. Semin Perinatol 2010, 34(1):3-19.
11. Wilder R.T., Flick R.P., Sprung J., et al. Early exposure to anesthesia and learning disabilities in apopulation-based birth cohort. Anesthesiology 2009, 110(4):796-804.
12. Rutherford M., Srinivasan L., Dyet L., et al. Magnetic resonance imaging in perinatal brain injury: clinical presentation, lesions and outcome. Pediatr Radiol 2006, 36(7):582-592.
13. Kanal E., Barkovich A.J., Bell C., et al. ACR guidance document for safe MR practices: 2007. AJR Am J Roentgenol 2007, 188(6):1447-1474.
14. Stokowski L.A. Ensuring safety for infants undergoing magnetic resonance imaging. Adv Neonatal Care 2005, 5(1):14-27. [quiz: 52-14].
15. Benavente-Fernandez I., Lubian-Lopez P.S., Zuazo-Ojeda M.A., et al. Safety of magnetic resonance imaging in preterm infants. Acta Paediatr 2010, 99(6):850-853.
16. Pennock JM. Patient preparation, safety and hazards in imaging infants and children. In: Rutherford MA, editor. MRI of the neonatal brain. Saunders Ltd; 2001. Chapter 01. Available at: Accessed March 14, 2011. http://www.mrineonatalbrain.com.
17. Woods T.O. Guidance for industry and FDA staff: establishing safety and compatibility of passive implants in the magnetic resonance (MR) environment 2008, Food and Drug Administration, Rockville (MD).
18. ASTM Standard practice for marking medical devices and other items for safety in the magnetic resonance environment. Vol F2503-05 2005, ASTM International, West Conshohocken (PA).
19. Reykowski A. RF coil safety - weekend categorical course. Joint Annual Meeting ISMRM-ESMRMB. Berlin (Germany), May 19-25, 2007.
20. EN/IEC 60601-2-33-Medical Electrical Equipment - Part 2: particular requirements for the safety of magnetic resonance equipment for medical diagnosis. IEC 60601: International Standard.
21. Guidance for industry and FDA staff. Criteria for significant risk investigations of magnetic resonance diagnostic devices 2003, Food and Drug Administration, Rockville (MD).
22. Maalouf EF, Counsell SJ. Imaging the preterm infant: practical issues. In: Rutherford MA, editor. MRI of the neonatal brain. Saunders Ltd; 2001. Chapter 02. Available at: Accessed March 14, 2011. http://www.mrineonatalbrain.com.
23. Murkovic I., Steinberg M.D., Murkovic B. Sensors in neonatal monitoring: current practice and future trends. Technol Health Care 2003, 11(6):399-412.
24. Theobald K., Botwinski C., Albanna S., et al. Apnea of prematurity: diagnosis, implications for care, and pharmacologic management. Neonatal Netw 2000, 19(6):17-24.
25. Philbin M.K., Taber K.H., Hayman L.A. Preliminary report: changes in vital signs of term newborns during MR. AJNR Am J Neuroradiol 1996, 17(6):1033-1036.
26. Taber K.H., Hayman L.A., Northrup S.R., et al. Vital sign changes during infant magnetic resonance examinations. J Magn Reson Imaging 1998, 8(6):1252-1256.
27. Shellock F.G. Reference manual for magnetic resonance safety, implants, and devices: 2011 edition 2011, Biomedical Research Publishing Group, Los Angeles (CA).
28. ® IC installed units Available at:, Accessed September 24, 2011. http://lammersmedical.com/e/pages/about-us/customer.php.
29. Bluml S., Friedlich P., Erberich S., et al. MR imaging of newborns by using an MR-compatible incubator with integrated radiofrequency coils: initial experience. Radiology 2004, 231(2):594-601.
30. Erberich S.G., Friedlich P., Seri I., et al. Functional MRI in neonates using neonatal head coil and MR compatible incubator. Neuroimage 2003, 20(2):683-692.
31. Whitby E.H., Griffiths P.D., Lonneker-Lammers T., et al. Ultrafast magnetic resonance imaging of the neonate in a magnetic resonance-compatible incubator with a built-in coil. Pediatrics 2004, 113(2):e150-e152.
32. Dumoulin C.L., Rohling K.W., Piel J.E., et al. Magnetic resonance imaging compatible neonate incubator. Concept Magnetic Res 2002, 15(2):117-128.
33. Barkovich A.J. MR imaging of the neonatal brain. Neuroimaging Clin N Am 2006, 16(1):117-135. viii-ix.
34. Prager A., Roychowdhury S. Magnetic resonance imaging of the neonatal brain. Indian J Pediatr 2007, 74(2):173-184.
35. Greenberg S.B., Faerber E.N., Aspinall C.L., et al. High-dose chloral hydrate sedation for children undergoing MR imaging: safety and efficacy in relation to age. AJR Am J Roentgenol 1993, 161(3):639-641.
36. Bisset G.S., Ball W.S. Preparation, sedation, and monitoring of the pediatric patient in the magnetic resonance suite. Semin Ultrasound CT MR 1991, 12(5):376-378.
37. Rutherford M., Malamateniou C., McGuinness A., et al. Magnetic resonance imaging in hypoxic-ischaemic encephalopathy. Early Human Dev 2010, 86(6):351-360.
38. Litman R.S., Soin K., Salam A. Chloral hydrate sedation in term and preterm infants: an analysis of efficacy and complications. Anesth Analg 2010, 110(3):739-746.
39. Rutherford M.A., Ward P., Malamatentiou C. Advanced MR techniques in the term-born neonate with perinatal brain injury. Semin Fetal Neonatal Med 2005, 10(5):445-460.
40. Mason K.P. The pediatric sedation service: who is appropriate to sedate, which medications should I use, who should prescribe the drugs, how do I bill?. Pediatr Radiol 2008, 38(Suppl 2):S218-S224.
41. Shankar V.R. Sedating children for radiological procedures: an intensivist's perspective. Pediatr Radiol 2008, 38(Suppl 2):S213-S217.
42. Mellon R.D., Simone A.F., Rappaport B.A. Use of anesthetic agents in neonates and young children. Anesth Analg 2007, 104(3):509-520.
43. Vigneron D.B., Barkovich A.J., Noworolski S.M., et al. Three-dimensional proton MR spectroscopic imaging of premature and term neonates. AJNR Am J Neuroradiol 2001, 22(7):1424-1433.
44. Dagia C., Ditchfield M. 3T MRI in paediatrics: challenges and clinical applications. Eur J Radiol 2008, 68(2):309-319.
45. Kliegman M.R., Behrman R.E., Jenson H.B., et al. Nelson textbook of pediatrics e-dition, 18th edition & atlas of pediatric physical diagnosis, 5th edition package 2007, Saunders, Philadelphia. 18th edition.
46. Hoult D., Richards R. The signal-to-noise ratio of the nuclear magnetic resonance experiment. JMR 1976, 24:71-85.
47. Edelstein W.A., Glover G.H., Hardy C.J., et al. The intrinsic signal-to-noise ratio in NMR imaging. Magn Reson Med 1986, 3(4):604-618.
48. Arthur R. Magnetic resonance imaging in preterm infants. Pediatr Radiol 2006, 36(7):593-607.
49. Abragam A. The principles of nuclear magnetism 1983, Clarendon Press, Oxford (United Kingdom). 3rd edition.
50. Harrington R. Time-harmonic electromagnetic fields 1961, McGraw-Hill, New York.
51. Vesselle H. High-frequency electromagnetic effects and signal-to-noise ratios of surface coils for magnetic resonance imaging [PhD dissertation] 1990, Case Western Reserve University, Cleveland (OH).
52. Wang J., Reykowski A., Dickas J. Calculation of the signal-to-noise ratio for simple surface coils and arrays of coils. IEEE Trans Biomed Eng 1995, 42(9):908-917.
53. Roemer P, Edelstein WA. Ultimate sensitivity limit of surface coils. SMRM 6th Annual Meeting. New York (NY), 1987. p. 410.
54. Schnell W., Renz W., Vester M., et al. Ultimate signal-to-noise-ratio of surface and body antennas for magnetic resonance imaging. IEEE T Antenn Propag 2000, 48(3):418-428.
55. Ehrenkranz R.A., Younes N., Lemons J.A., et al. Longitudinal growth of hospitalized very low birth weight infants. Pediatrics 1999, 104(2 Pt 1):280-289.
56. Kuczmarski R.J., Ogden C.L., Grummer-Strawn L.M., et al. CDC growth charts: United States. Adv Data 2000, (314):1-27.
57. Fenton T.R. A new growth chart for preterm babies: Babson and Benda's chart updated with recent data and a new format. BMC Pediatr 2003, 3:13.
58. Keil B., Alagappan V., Mareyam A., et al. Size-optimized 32-channel brain arrays for 3 T pediatric imaging. Magn Reson Med 2011, [Epub ahead of print]. 10.1002/mrm.22961.
59. Parikh P.T., Sandhu G.S., Blackham K.A., et al. Evaluation of image quality of a 32-channel versus a 12-channel head coil at 1.5T for MR imaging of the brain. AJNR Am J Neuroradiol 2011, 32(2):365-373.
60. Pruessmann K.P., Weiger M., Scheidegger M.B., et al. Sensitivity encoding for fast MRI. Magn Reson Med 1999, 42(5):952-962.
61. Griswold M.A., Jakob P.M., Heidemann R.M., et al. Generalized autocalibrating partially parallel acquisitions (GRAPPA). Magn Reson Med 2002, 47(6):1202-1210.
62. Wiggins G.C., Triantafyllou C., Potthast A., et al. 32-channel 3 Tesla receive-only phased-array head coil with soccer-ball element geometry. Magn Reson Med 2006, 56(1):216-223.
63. Horbar J.D., Badger G.J., Carpenter J.H., et al. Trends in mortality and morbidity for very low birth weight infants, 1991-1999. Pediatrics 2002, 110(1 Pt 1):143-151.
64. Lin W., Huang F., Bornert P., et al. Motion correction using an enhanced floating navigator and GRAPPA operations. Magn Reson Med 2010, 63(2):339-348.
65. Reykowski A., Schnell W., Wang J. Simulation of SNR limit for SENSE related reconstruction techniques [abstract] 2002, ISMRM, Honolulu (HI), p. 2385.
66. Reykowski A. How to calculate the SNR limit of SENSE related reconstruction techniques [abstract] 2002, ISMRM, Honolulu (HI), p. 905.
67. Ohliger M.A., Grant A.K., Sodickson D.K. Ultimate intrinsic signal-to-noise ratio for parallel MRI: electromagnetic field considerations. Magn Reson Med 2003, 50(5):1018-1030.
68. Wiesinger F., Boesiger P., Pruessmann K.P. Electrodynamics and ultimate SNR in parallel MR imaging. Magn Reson Med 2004, 52(2):376-390.
69. Duensing G.R., Akao J., Saylor C., et al. Conductor losses in many channel RF coil arrays 2004, ISMRM, Kyoto (Japan), p. 1583.
70. Hall A.S., Young I.R., Davies F.J., et al. A dedicated magnetic resonance system in a neonatal intensive therapy unit. Advanced MR imaging techniques 1997, 281-289. Martin Dunitz, London. W.G. Bradley, G.M. Bydder (Eds.).
71. Whitby E.H., Paley M.N., Smith M.F., et al. Low field strength magnetic resonance imaging of the neonatal brain. Arch Dis Child Fetal Neonatal Ed 2003, 88(3):F203-F208.
72. Tkach JA, Giaquinto R, Loew W, et al. Imaging system for imaging neonates in the NICU. Paper presented at: 6th Congress and Exhibition of the Joint Societies of Paediatric Radiology. London, May 29, 2011.